Lamictal combined with Topiramate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hippocampal Sclerosis Other Serious 12 Female 2/21/2006 Switzerland
Primary
Secondary
Tonic Convulsion Other Serious 15 Male 6/15/2006 United Kingdom
Primary
Secondary
Tonic Convulsion 29 Male 212 lb 1/30/2006 Pharmacist United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2006 31 Male 8/4/2006 Consumer United States
Primary
Concomitant
Mental Impairment Other Serious 10/11/2004 17 Female 107 lb 10/3/2006 France
Primary
Concomitant
Rash 26 Female 2/28/2007 Consumer United States
Primary
Concomitant
Joint Sprain Other Serious 10/11/2004 17 Female 107 lb 5/2/2007 Physician France
Primary
Concomitant
Tremor Hospitalization 9/1/2007 57 Female 10/17/2007 Consumer South Africa
Primary
Concomitant
Radiculopathy Other Serious 10/11/2004 17 Female 107 lb 11/14/2007 Physician France
Primary
Concomitant
Tremor Hospitalization 9/1/2007 57 Female 12/14/2007 Consumer South Africa
Primary
Concomitant
Vomiting Hospitalization 12/5/2007 18 Female 12/6/2007 United States
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 1/1/2008 Female 176 lb 4/18/2008 Physician Austria
Primary
Secondary
Pulmonary Embolism Hospitalization 2/20/2008 Male 7/28/2008 Physician France
Primary
Secondary
Neonatal Disorder Required Intervention Male 9/2/2008 United Kingdom
Primary
Secondary
Maternal Drugs Affecting Foetus Required Intervention Female 9/2/2008 United Kingdom
Primary
Secondary
Maternal Drugs Affecting Foetus Required Intervention Male 9/2/2008 United Kingdom
Primary
Secondary
Neonatal Disorder Required Intervention Female 9/2/2008 United Kingdom
Primary
Secondary
Small For Dates Baby Congenital Anomaly Male 6 lb 9/2/2008 United Kingdom
Primary
Secondary
Talipes Required Intervention Male 9/2/2008 United Kingdom
Primary
Secondary
Maternal Drugs Affecting Foetus Required Intervention Female 9/2/2008 United Kingdom
Primary
Secondary
Maternal Drugs Affecting Foetus Required Intervention Male 9/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Maternal Drugs Affecting Foetus Required Intervention Male 9/2/2008 United Kingdom
Primary
Secondary
Retrognathia Congenital Anomaly 1/1/2008 Female 8 lb 12/12/2008 Other Health Professional France
Primary
Secondary
Retrognathia Congenital Anomaly 1/1/2008 Female 12/15/2008 Consumer France
Primary
Secondary
Retrognathia Other Serious Female 12/16/2008 Other Health Professional France
Primary
Secondary
Therapeutic Response Decreased Life Threatening 11/19/2008 46 Female 12/19/2008 Other Health Professional France
Primary
Concomitant
Vomiting Other Serious 51 Female 198 lb 2/11/2009 Consumer United States
Primary
Secondary
Concomitant
Viral Infection Hospitalization 2/18/2009 Male 4/7/2009 Physician Japan
Primary
Concomitant
Viral Infection Hospitalization 2/18/2009 Male 4/20/2009 Physician Japan
Primary
Concomitant
Product Substitution Issue Other Serious 4/15/2009 65 Female 155 lb 4/16/2009 Other Health Professional United States
Primary
Concomitant
Viral Infection Hospitalization 2/18/2009 Male 4/21/2009 Physician Japan
Primary
Concomitant
Inguinal Hernia Other Serious 3/5/2009 Female 7 lb 5/11/2009 Physician United States
Primary
Concomitant
Muscle Spasms Other Serious 7/16/2007 31 Female 5/12/2009 Consumer United States
Primary
Concomitant
Status Epilepticus Other Serious 4/14/2009 12 Male 62 lb 5/18/2009 Physician Japan
Primary
Concomitant
Viral Infection Hospitalization 2/18/2009 Male 5/21/2009 Physician Japan
Primary
Concomitant
Status Epilepticus Other Serious 4/14/2009 12 Male 62 lb 5/27/2009 Physician Japan
Primary
Concomitant
Myalgia Hospitalization 5/16/2009 Male 6/3/2009 Physician Japan
Primary
Concomitant
Product Substitution Issue Other Serious 5/1/2009 Female 77 lb 6/10/2009 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 4/1/2009 Female 6/26/2009 Physician Japan
Primary
Concomitant
Rash Hospitalization 6/1/2009 Female 7/16/2009 Pharmacist Japan
Primary
Concomitant
Rash Hospitalization 6/1/2009 10 Female 35 lb 8/6/2009 Pharmacist Japan
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2006 15 Male 113 lb 8/13/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2006 15 Male 113 lb 8/5/2009 United States
Primary
Secondary
Concomitant
Viral Infection Hospitalization 2/18/2009 Male 9/14/2009 Physician Japan
Primary
Concomitant
Grand Mal Convulsion Other Serious 6/12/2009 62 Female 9/8/2009 United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/20/2004 46 Male 234 lb 10/5/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 4/1/2009 Female 10/7/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 4/1/2009 Female 11/23/2009 Physician Japan
Primary
Concomitant
Stomatitis Hospitalization 8/7/2009 35 Female 11/25/2009 Physician Japan
Primary
Concomitant
Retrognathia Congenital Anomaly 1/1/2008 Female 12/10/2009 France
Primary
Secondary
Hallucination, Visual Other Serious 8/5/2009 30 Male 117 lb 1/4/2010 Japan
Primary
Secondary
Concomitant
Rash Maculo-papular Other Serious 1/9/2010 Female 179 lb 2/10/2010 Consumer Australia
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 35 Female 5/7/2010 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 3/30/2010 78 Male 5/18/2010 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 1/1/2009 12 Female 101 lb 6/1/2010 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 4/1/2009 14 Female 6/25/2010 Physician Japan
Primary
Concomitant
Status Epilepticus Hospitalization 3/18/2009 7 Female 7/2/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 3/30/2010 78 Male 7/9/2010 Physician Japan
Primary
Secondary
Concomitant
Hyperlipasaemia Hospitalization 7/7/2010 19 Female 8/2/2010 Physician France
Primary
Secondary
Concomitant
Hyperlipasaemia Hospitalization 7/7/2010 19 Female 8/3/2010 Physician France
Primary
Secondary
Concomitant
Drug Withdrawal Syndrome 6/23/2010 35 Female 230 lb 8/5/2010 United States
Primary
Concomitant
Drug Withdrawal Syndrome 6/23/2010 35 Female 230 lb 8/19/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 10/11/2004 17 Female 107 lb 9/1/2010 France
Primary
Concomitant
Encephalopathy Hospitalization 4/20/2010 2 Female 26 lb 9/8/2010 Physician Japan
Primary
Concomitant
Rash Other Serious 1/1/2009 12 Female 90 lb 9/24/2010 Physician France
Primary
Secondary
Concomitant
Nausea Other Serious 47 Female 10/13/2010 Consumer United States
Primary
Secondary
Concomitant
Optic Neuropathy Hospitalization 10/1/2009 22 Female 10/15/2010 Physician France
Primary
Secondary
Optic Neuropathy Other Serious 10/1/2009 22 Female 10/21/2010 Other Health Professional France
Primary
Secondary
Optic Neuropathy Hospitalization 10/1/2009 22 Female 10/21/2010 Other Health Professional France
Primary
Secondary
Vision Blurred Hospitalization 10/1/2009 22 Female 10/22/2010 Consumer France
Primary
Secondary
Visual Field Defect Hospitalization 10/1/2009 22 Female 10/25/2010 Other Health Professional France
Primary
Secondary
Concomitant
Nausea Other Serious 10/1/2010 47 Female 10/29/2010 Consumer United States
Primary
Secondary
Concomitant
Status Epilepticus Hospitalization 4/20/2010 2 Female 26 lb 11/1/2010 Physician Japan
Primary
Concomitant
Tongue Ulceration Hospitalization 8/28/2010 48 Female 11/5/2010 Physician Japan
Primary
Concomitant
Status Epilepticus Hospitalization 4/20/2010 2 Female 26 lb 11/9/2010 Physician Japan
Primary
Concomitant
Optic Neuropathy Hospitalization 10/1/2009 22 Female 11/10/2010 Other Health Professional France
Primary
Secondary
Concomitant
Mental Impairment Disability 6/10/2010 27 Male 11/18/2010 Physician Japan
Primary
Concomitant
Tongue Ulceration Hospitalization 8/28/2010 48 Female 11/22/2010 Physician Japan
Primary
Concomitant
Encephalitis Herpes Hospitalization 9/15/2010 14 Male 150 lb 12/6/2010 Physician Japan
Primary
Concomitant
Hallucination, Visual Hospitalization 11/2/2010 67 Male 12/10/2010 Other Health Professional Japan
Primary
Concomitant
Encephalitis Herpes Hospitalization 9/15/2010 14 Male 150 lb 12/13/2010 Physician Japan
Primary
Concomitant
Withdrawal Syndrome Other Serious 47 Female 12/17/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 23 Female 110 lb 12/21/2010 Physician Denmark
Primary
Secondary
Hallucination Hospitalization 12/1/2010 33 Female 84 lb 1/21/2011 Consumer Japan
Primary
Secondary
Influenza Like Illness 1/1/2010 52 Female 262 lb 1/29/2011 Consumer United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 1/31/2011 52 Female 163 lb 2/7/2011 Consumer United States
Primary
Concomitant
Muscle Tightness Hospitalization 10/26/2010 63 Female 140 lb 11/17/2010 Pharmacist United States
Primary
Concomitant
Drug Interaction Hospitalization 11/16/2010 33 Female 80 lb 2/15/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Hallucination, Visual Hospitalization 11/2/2010 67 Male 3/7/2011 Other Health Professional Japan
Primary
Concomitant
Myoclonic Epilepsy Hospitalization 7/1/2005 6 Male 49 lb 2/24/2011 Other Health Professional Germany
Primary
Concomitant
Anxiety Disability 1/1/2009 12 Female 90 lb 3/10/2011 Physician France
Primary
Secondary
Concomitant
Visual Field Defect Hospitalization 10/1/2009 22 Female 3/25/2011 Other Health Professional France
Primary
Secondary
Concomitant
Hallucination Hospitalization 12/9/2010 33 Female 84 lb 3/29/2011 Physician Japan
Primary
Secondary
Product Taste Abnormal Other Serious 11/22/2010 22 Female 3/24/2011 Other Health Professional United States
Primary
Concomitant
Fanconi Syndrome Acquired Other Serious 9/21/2010 Male 4/14/2011 Physician Japan
Primary
Secondary
Concomitant
Altered State Of Consciousness Hospitalization 8/26/2010 73 Male 4/19/2011 Other Health Professional Japan
Primary
Concomitant
Optic Neuropathy Hospitalization 10/1/2009 22 Female 5/4/2011 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Other Serious 6/15/2010 27 Male 196 lb 5/20/2011 Physician Japan
Primary
Concomitant
Status Epilepticus Hospitalization 8/26/2010 73 Male 5/23/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Tracheostomy Other Serious 9/21/2008 16 Female 5/27/2011 Consumer United States
Primary
Secondary
Concomitant
Dermatitis Contact Female 5/3/2011 Physician United States
Primary
Concomitant
Inguinal Hernia Other Serious 3/5/2009 Female 7 lb 6/20/2011 Physician United States
Primary
Secondary
Status Epilepticus Other Serious 9/20/2010 48 Female 6/21/2011 Physician France
Primary
Concomitant
Haematocrit Decreased Other Serious 9/10/2009 21 Female 6/24/2011 Physician Japan
Primary
Concomitant
Menometrorrhagia Hospitalization 10/1/2010 36 Female 183 lb 7/1/2011 Physician Germany
Primary
Secondary
Hypokalaemia Hospitalization 6/27/2011 16 Female 8/12/2011 Physician France
Primary
Secondary
Concomitant
Convulsion Other Serious 67 Male 8/15/2011 Other Health Professional Japan
Primary
Concomitant
Drug Intolerance Hospitalization 6/27/2011 16 Female 8/16/2011 Other Health Professional France
Primary
Secondary
Concomitant
Hypokalaemia Other Serious 6/29/2011 16 Female 8/18/2011 Other Health Professional France
Primary
Secondary
Concomitant
Gingival Bleeding Disability 1/1/2008 59 Female 193 lb 8/19/2011 Consumer France
Primary
Concomitant
Oculomucocutaneous Syndrome Hospitalization 51 Female 8/19/2011 Physician Japan
Primary
Concomitant
Product Adhesion Issue 6/1/2011 48 Female 186 lb 8/23/2011 Consumer United States
Primary
Concomitant
Guillain-barre Syndrome Hospitalization 10/11/2004 17 Female 107 lb 8/30/2011 Physician France
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 7/17/2011 53 Male 9/1/2011 Physician Japan
Primary
Concomitant
Feeling Abnormal Other Serious 1/1/2008 67 Male 9/2/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Band Neutrophil Percentage Increased Hospitalization 8/4/2011 51 Female 9/2/2011 Physician Japan
Primary
Concomitant
Feeling Abnormal Other Serious 1/1/2008 67 Male 9/6/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Rash Hospitalization 6/20/2010 7 Female 33 lb 9/13/2011 Physician Japan
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 7/27/2011 19 Female 9/14/2011 Physician Japan
Primary
Concomitant
Haematocrit Increased Hospitalization 8/4/2011 51 Female 9/19/2011 Physician Japan
Primary
Concomitant
Myocarditis Hospitalization 6/20/2010 7 Female 33 lb 9/21/2011 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/4/2011 51 Female 9/23/2011 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 9/1/2011 2 Female 42 lb 9/30/2011 Physician Germany
Primary
Secondary
Mucosal Erosion Hospitalization 8/4/2011 51 Female 10/5/2011 Physician Japan
Primary
Concomitant
Drug Eruption Hospitalization 4/1/2011 6 Female 51 lb 10/12/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Attention Deficit/hyperactivity Disorder Hospitalization 8/23/2011 52 Female 10/26/2011 Physician Switzerland
Primary
Concomitant
Calculus Urinary Hospitalization 5/11/2009 10 Male 11/9/2011 Other Health Professional Japan
Primary
Concomitant
Inguinal Hernia Other Serious 3/5/2009 Female 7 lb 11/15/2011 Physician United States
Primary
Secondary
Suicidal Ideation Hospitalization 1/14/2003 34 Male 11/21/2011 Consumer United States
Primary
Concomitant
Status Epilepticus Hospitalization 9/20/2010 47 Female 154 lb 11/24/2011 Physician France
Primary
Concomitant
Hypercalciuria Other Serious 1/1/2003 60 Female 12/2/2011 Physician France
Primary
Concomitant
Pyelonephritis Acute Other Serious 5/11/2009 10 Male 44 lb 12/2/2011 Other Health Professional Japan
Primary
Concomitant
Schizophrenia Other Serious 1/19/2011 20 Female 105 lb 12/19/2011 Physician Japan
Primary
Concomitant
Rash Hospitalization 11/17/2011 41 Female 12/28/2011 Physician Japan
Primary
Concomitant
Blood Immunoglobulin G Decreased Hospitalization 4/1/2009 14 Female 1/4/2012 Physician Japan
Primary
Concomitant
Cardiomegaly Hospitalization 6/20/2010 7 Female 33 lb 1/6/2012 Physician Japan
Primary
Secondary
Concomitant
C-reactive Protein Increased Hospitalization 11/27/2011 18 Female 57 lb 1/24/2012 Physician Japan
Primary
Concomitant
Sleep Paralysis Hospitalization 2/22/2009 22 Female 155 lb 1/26/2012 Physician United States
Primary
Concomitant
Injection Site Erythema 11/1/2008 35 Female 1/27/2012 Consumer United States
Primary
Concomitant
Thyroid Function Test Abnormal Hospitalization 6/20/2010 7 Female 33 lb 2/1/2012 Physician Japan
Primary
Secondary
Concomitant
Blood Creatine Phosphokinase Increased Hospitalization 6/20/2010 7 Female 33 lb 2/15/2012 Physician Japan
Primary
Secondary
Concomitant
Schizophrenia Other Serious 1/19/2011 20 Female 105 lb 2/17/2012 Physician Japan
Primary
Concomitant
Dermatitis Bullous Other Serious 1/3/2012 3 Male 40 lb 2/21/2012 Physician France
Primary
Concomitant
Blood Calcium Decreased Other Serious 7/16/2011 15 Male 2/29/2012 Physician Japan
Primary
Concomitant
Product Substitution Issue Life Threatening 3/30/2010 Male 7/19/2011 Other Health Professional United States
Primary
Concomitant
Skin Disorder Hospitalization 2/20/2012 34 Female 3/1/2012 Physician Japan
Primary
Secondary
Concomitant
Adverse Drug Reaction Hospitalization 1/1/2009 39 Female 12/13/2011 United States
Primary
Concomitant
Blood Alkaline Phosphatase Increased Other Serious 7/15/2011 15 Male 3/13/2012 Physician Japan
Primary
Concomitant
Eosinophilia Hospitalization 2/1/2010 84 Female 110 lb 4/13/2012 Physician France
Primary
Concomitant
Abscess Hospitalization 7/27/2009 9 Male 35 lb 5/30/2012 Physician Japan
Primary
Concomitant

Drug Data