Lactulose combined with Zopiclone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hyperglycaemia Hospitalization 6/1/2004 Female 161 lb 1/27/2006 Physician United Kingdom
Primary
Concomitant
Weight Decreased Life Threatening 11/1/2005 Male 4/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 4/8/2006 84 Male 5/3/2006 Physician France
Primary
Concomitant
Pyrexia Hospitalization 4/8/2006 84 Male 5/16/2006 Physician France
Primary
Concomitant
Feeling Drunk Hospitalization 5/10/2005 52 Female 152 lb 5/25/2006 Pharmacist United Kingdom
Primary
Concomitant
Hypomagnesaemia Life Threatening 6/9/2006 62 Female 7/6/2006 Pharmacist United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 3/18/2006 85 Male 7/14/2006 Physician France
Primary
Concomitant
White Blood Cell Count Increased Other Serious 5/12/2006 36 Female 8/16/2006 Physician United Kingdom
Primary
Secondary
Grand Mal Convulsion Disability 2/1/2005 52 Female 8/29/2006
Primary
Concomitant
Blood Potassium Decreased Life Threatening 6/9/2006 Female 9/1/2006 Consumer United Kingdom
Primary
Concomitant
Hypoglycaemia Other Serious 1/16/2006 23 Female 196 lb 9/12/2006 Consumer United Kingdom
Primary
Concomitant
Thrombocythaemia Hospitalization 1/1/2006 79 Female 10/6/2006 Physician France
Primary
Concomitant
White Blood Cell Count Increased Other Serious 5/12/2006 36 Female 10/24/2006 Pharmacist United Kingdom
Primary
Secondary
Thrombocythaemia Hospitalization 1/1/2006 79 Female 10/30/2006 Physician France
Primary
Concomitant
White Blood Cell Count Increased Other Serious 5/12/2006 36 Female 11/10/2006 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/1/2006 85 Male 11/9/2006 Physician France
Primary
Concomitant
Vertigo Hospitalization 5/1/2006 91 Male 11/28/2006 Sweden
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/5/2007
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/8/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/9/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/11/2007 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/17/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/11/2007 United Kingdom
Primary
Secondary
Concomitant
Myocardial Ischaemia Death 84 Male 105 lb 2/5/2007 Physician United Kingdom
Primary
Concomitant
Vision Blurred Other Serious 77 Male 4/2/2007 Physician Sweden
Primary
Concomitant
Hallucination, Visual Hospitalization 3/14/2007 Female 126 lb 4/17/2007 Other Health Professional France
Primary
Secondary
Concomitant
Speech Disorder Other Serious 3/15/2007 39 Female 132 lb 4/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Small Intestinal Haemorrhage Life Threatening 4/24/2005 44 Female 5/9/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Haemorrhage Hospitalization 4/22/2007 Female 168 lb 5/25/2007 Norway
Primary
Concomitant
Renal Haemorrhage Hospitalization 4/22/2007 Female 168 lb 5/29/2007 Norway
Primary
Concomitant
Vision Blurred Other Serious 77 Male 6/1/2007 Physician Sweden
Primary
Concomitant
Thrombocytopenia Death 72 Male 6/4/2007 Consumer Canada
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/1/2007 53 Female 141 lb 6/15/2007 Pharmacist Germany
Primary
Concomitant
Pancreatitis Acute Hospitalization 6/1/2006 Male 7/6/2007 Physician France
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9 Male 7/10/2007 Other Health Professional Sweden
Primary
Concomitant
Visual Disturbance Other Serious 6/27/2007 69 Male 8/1/2007 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9 Male 8/3/2007 Other Health Professional Sweden
Primary
Concomitant
Postoperative Wound Infection Hospitalization 2/5/2004 75 Female 176 lb 8/1/2007 Other Health Professional Germany
Primary
Concomitant
Wound Infection Bacterial Hospitalization 2/5/2004 75 Female 176 lb 9/10/2007 Consumer Germany
Primary
Concomitant
Wound Infection Bacterial Hospitalization 2/5/2004 75 Female 176 lb 9/18/2007 Consumer Germany
Primary
Concomitant
Toxic Epidermal Necrolysis Required Intervention 10 Male 9/17/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Ulcer Hospitalization 9/24/2007 Male 10/8/2007 United Kingdom
Primary
Concomitant
Wound Infection Bacterial Hospitalization 2/5/2004 75 Female 176 lb 10/10/2007 Consumer Germany
Primary
Concomitant
Underweight Hospitalization 19 Female 11/7/2007 United Kingdom
Primary
Concomitant
Pancreatitis Acute Hospitalization 6/1/2006 Male 11/12/2007 Physician France
Primary
Concomitant
General Physical Health Deterioration Life Threatening 11/6/2006 82 11/16/2007 Physician Germany
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 10 Male 11/8/2007 Sweden
Primary
Secondary
Concomitant
General Physical Health Deterioration Life Threatening 11/6/2006 82 Female 11/15/2007 Germany
Primary
Secondary
Bowel Movement Irregularity Hospitalization 8/29/2007 71 Male 11/30/2007 Physician Sweden
Primary
Secondary
Concomitant
Rectal Cancer Metastatic Hospitalization 6/1/2007 87 Male 143 lb 11/30/2007 Consumer Germany
Primary
Concomitant
Constipation Hospitalization 8/29/2007 71 Male 12/6/2007 Physician Sweden
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 10 Male 12/14/2007 Sweden
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/1/2007 87 Male 143 lb 12/14/2007 Consumer Germany
Primary
Concomitant
Respiratory Arrest Life Threatening 9/1/1998 76 Female 1/18/2008 Other Health Professional Finland
Primary
Concomitant
Constipation Hospitalization 8/29/2007 71 Male 1/23/2008 Physician Sweden
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 87 Male 3/17/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 5/1/2007 87 Male 143300 lb 3/14/2008 Physician Germany
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 3/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 87 Male 3/28/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 87 Male 3/31/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Death Female 4/16/2008 Ireland
Primary
Concomitant
Cerebral Haematoma Hospitalization 8/10/2006 Female 5/13/2008 France
Primary
Concomitant
Renal Failure Hospitalization 5/1/2007 87 Male 143 lb 6/11/2008 Consumer Germany
Primary
Concomitant
Post Procedural Haemorrhage Hospitalization 4/20/2008 63 Male 119 lb 6/23/2008 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Hospitalization 8/6/2004 66 Male 151 lb 6/20/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Hypotension Hospitalization 7/22/2008 Female 9/2/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 6/24/2008 Male 188 lb 8/27/2008 Canada
Primary
Secondary
Concomitant
Hypotension Hospitalization 7/22/2008 Female 9/4/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 8/4/2008 Female 93 lb 9/5/2008 United Kingdom
Primary
Secondary
Concomitant
Alveolitis Allergic Hospitalization 5/8/2008 Female 10/14/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 2/5/2008 Male 10/16/2008 Consumer Germany
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 10/1/2006 91 Male 11/18/2008 Consumer Canada
Primary
Secondary
Concomitant
Postmenopausal Haemorrhage Hospitalization 9/1/2008 12/19/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Postmenopausal Haemorrhage Hospitalization 9/1/2008 77 Female 12/24/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Grand Mal Convulsion Other Serious 37 Male 176 lb 1/23/2009 Pharmacist Canada
Primary
Secondary
Concomitant
Muscle Twitching Other Serious 11/14/2008 60 Male 2/5/2009 Physician Norway
Primary
Secondary
Concomitant
Muscle Twitching Other Serious 11/14/2008 60 Male 2/25/2009 Physician Norway
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 80 Male 2/26/2009 Other Health Professional United Kingdom
Primary
Concomitant
Confusional State Other Serious 12/16/2008 33 Male 3/6/2009 Physician Netherlands
Primary
Secondary
Concomitant
Muscle Twitching Other Serious 11/14/2008 3/11/2009 Physician Norway
Primary
Secondary
Concomitant
Unresponsive To Stimuli Life Threatening 1/2/2009 78 Male 3/26/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Interacting
Purpura Hospitalization 3/17/2009 75 Male 3/27/2009 Physician France
Primary
Concomitant
Pulmonary Oedema Other Serious 10/1/2006 Male 4/5/2009 Consumer Canada
Primary
Concomitant
Spinal Column Stenosis Hospitalization 2/5/2004 75 Female 176 lb 4/2/2009 Other Health Professional Germany
Primary
Concomitant
Metastases To Liver Other Serious Female 145 lb 4/16/2009 Canada
Primary
Concomitant
Hypertensive Crisis Life Threatening 1/19/2009 Male 4/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 8/4/2008 5/5/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 7/12/2006 36 Female 6/15/2009 Other Health Professional United Kingdom
Primary
Secondary
Somnolence Other Serious 4/30/2009 Female 6/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 5/12/2006 Female 6/19/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 7/12/2006 36 Female 6/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/12/2006 36 Female 6/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/4/2008 56 6/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 7/1/2006 36 Female 6/24/2009 United Kingdom
Primary
Secondary
Concomitant
Rash Other Serious 7/6/2009 75 Male 139 lb 7/31/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Other Serious 7/6/2009 75 Male 138 lb 8/6/2009 Physician United Kingdom
Primary
Concomitant
Leukocytoclastic Vasculitis Hospitalization 3/16/2009 75 Male 287 lb 8/27/2009 Physician France
Primary
Concomitant
Vitreous Haemorrhage Other Serious 4/1/2009 65 Male 9/15/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 9/16/2009 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 9/16/2009 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 7/12/2006 36 Female 11/4/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 5/12/2006 35 Female 11/4/2009 United Kingdom
Primary
Secondary
Platelet Count Increased Other Serious 12/16/2008 Female 11/10/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 5/12/2006 Female 11/17/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Required Intervention 5/12/2006 36 Female 11/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 7/12/2006 36 Female 11/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 11/2/2006 79 Female 11/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Life Threatening 1/2/2009 78 Male 12/3/2009 Other Health Professional France
Primary
Secondary
Concomitant
Interacting
Pruritus Other Serious 10/1/2009 60 Male 265 lb 12/12/2009 Other Health Professional
Primary
Concomitant
Influenza Other Serious 12/5/2009 Male 12/22/2009 Pharmacist Canada
Primary
Concomitant
Neoplasm Progression Other Serious 12/5/2009 Male 1/4/2010 Physician Canada
Primary
Concomitant
Swelling Face Hospitalization 1/16/2010 75 Female 102 lb 2/10/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Swelling Face Other Serious 1/16/2010 75 Female 102 lb 2/16/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Swelling Face Other Serious 1/16/2010 75 Female 102 lb 2/18/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pruritus Other Serious 10/1/2009 60 Male 265 lb 2/25/2010 Other Health Professional
Primary
Concomitant
Sepsis Hospitalization 12/1/2009 Male 3/2/2010 Other Health Professional New Zealand
Primary
Concomitant
Swelling Face Hospitalization 1/16/2010 75 Female 102 lb 3/2/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Death Hospitalization Female 3/5/2010 Physician Canada
Primary
Concomitant
Ventricular Extrasystoles Other Serious 10/22/2009 Male 3/8/2010 Other Health Professional New Zealand
Primary
Concomitant
General Physical Health Deterioration Hospitalization 3/3/2010 Male 3/10/2010 Consumer United States
Primary
Concomitant
General Physical Health Deterioration Hospitalization 3/3/2010 57 Male 4/9/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 7/12/2006 36 Female 5/10/2010 Other Health Professional United Kingdom
Primary
Secondary
Pulmonary Oedema Other Serious 10/1/2006 89 Male 5/7/2010 Consumer Canada
Primary
Concomitant
Cerebral Haematoma Hospitalization 8/10/2006 61 Female 5/18/2010 Physician France
Primary
Concomitant
General Physical Health Deterioration Hospitalization 3/3/2010 57 Male 5/21/2010 Consumer United States
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 6/3/2010 Other Health Professional Italy
Primary
Concomitant
Intestinal Perforation Hospitalization 7/25/2010 74 Male 120 lb 8/2/2010 Consumer United States
Primary
Secondary
Concomitant
Skin Turgor Decreased Hospitalization 11/25/2009 99 Female 8/23/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Intestinal Perforation Hospitalization 7/25/2010 74 Male 120 lb 8/30/2010 Consumer United States
Primary
Secondary
Concomitant
Ulcer Hospitalization 9/24/2007 46 Female 9/1/2010 Physician United Kingdom
Primary
Concomitant
Rectal Haemorrhage Other Serious 8/8/2010 81 Female 165 lb 9/8/2010 Pharmacist Canada
Primary
Concomitant
Self Injurious Behaviour Hospitalization 74 Female 9/10/2010 Physician United Kingdom
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 8/29/2010 59 Female 110 lb 9/13/2010 Canada
Primary
Secondary
Concomitant
Peritonitis Hospitalization 7/25/2010 73 Male 119 lb 9/16/2010 Consumer United States
Primary
Secondary
Concomitant
Lung Consolidation Hospitalization 7/25/2010 74 Male 120 lb 9/10/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Intestinal Perforation Hospitalization 7/25/2010 74 Male 120 lb 9/22/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Peritonitis Hospitalization 7/25/2010 73 Male 119 lb 9/28/2010 Consumer United States
Primary
Secondary
Concomitant
Aphasia Other Serious 72 Male 161 lb 10/8/2010 Other Health Professional Canada
Primary
Concomitant
Psychotic Disorder Other Serious 1/1/2010 30 Female 10/20/2010 Pharmacist United Kingdom
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2010 35 Male 159 lb 10/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Treatment Noncompliance Hospitalization 5/27/2010 30 Male 10/28/2010 Physician United Kingdom
Primary
Concomitant
Intestinal Perforation Hospitalization 7/25/2010 74 Male 120 lb 10/26/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Intestinal Perforation Hospitalization 7/25/2010 74 Male 120 lb 10/27/2010 Consumer United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 3/16/2010 68 Male 11/19/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Haemorrhagic Stroke Hospitalization 11/4/2010 12/22/2010 Other Health Professional United Kingdom
Primary
Concomitant

Drug Data