Lactulose combined with Zolpidem

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 8/24/2004 65 9/12/2005 Physician United States
Primary
Concomitant
Shock Other Serious 46 Male 176 lb 7/31/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Shock Death 46 Male 176 lb 5/15/2007 Sweden
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 8/29/2007 52 Male 9/28/2007 Pharmacist Japan
Primary
Concomitant
Parkinsonism Other Serious 6/9/2007 64 Male 12/27/2007 Physician Germany
Primary
Concomitant
Interacting
Pneumonia Aspiration Hospitalization 8/9/2007 Male 91 lb 1/9/2008 Physician Korea, Republic Of
Primary
Concomitant
Suicidal Ideation Hospitalization 11/7/2006 Male 177 lb 2/20/2008 Consumer United States
Primary
Concomitant
Postnasal Drip Hospitalization 1/1/2007 83 Female 12/18/2007 Physician United States
Primary
Concomitant
Rash Other Serious 11/24/2007 Female 3/24/2008 Pharmacist United States
Primary
Concomitant
Respiratory Distress Life Threatening 3/2/2008 76 Male 6/2/2008 Other Health Professional France
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious Male 6/16/2008 Other Health Professional United Kingdom
Primary
Concomitant
Gastric Perforation Hospitalization 9/5/2008 Male 115 lb 9/16/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Tremor Other Serious 1/9/2003 34 Male 9/18/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Gastric Perforation Hospitalization 9/5/2008 Male 115 lb 9/30/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Ventricular Dysfunction Hospitalization 9/28/2008 Male 200 lb 10/6/2008 Consumer United States
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Hospitalization 1/21/2009 Female 101 lb 5/6/2009 United States
Primary
Concomitant
Vision Blurred Other Serious 1/21/2002 44 Female 144 lb 7/16/2009 United States
Primary
Concomitant
Social Problem Death 81 Female 7/14/2009 United States
Primary
Concomitant
Social Avoidant Behaviour Death 80 Female 7/20/2009 United States
Primary
Concomitant
Non-small Cell Lung Cancer Hospitalization 1/21/2009 Female 101 lb 8/17/2009 United States
Primary
Concomitant
Non-small Cell Lung Cancer Hospitalization 1/21/2009 Female 104 lb 8/24/2009 United States
Primary
Concomitant
Suicidal Ideation Hospitalization 11/7/2006 Male 177 lb 11/30/2009 Consumer United States
Primary
Concomitant
Patella Fracture Hospitalization 12/24/2009 Male 2/17/2010
Primary
Concomitant
Patella Fracture Hospitalization 12/24/2009 Male 2/25/2010
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 Male 3/4/2010 Lawyer United States
Primary
Concomitant
Vomiting Life Threatening 12/14/2007 69 Male 3/4/2010 Lawyer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/29/2008 86 Male 141 lb 2/26/2010 Other Health Professional United States
Primary
Concomitant
Uterine Cancer Hospitalization 29 Female 276 lb 2/24/2010 United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 3/23/2010 United States
Primary
Concomitant
Shock Hospitalization 12/19/2008 Male 141 lb 3/30/2010 Physician Taiwan, Province Of China
Primary
Concomitant
Weight Increased Hospitalization 11/29/2008 86 Male 141 lb 4/8/2010 Other Health Professional United States
Primary
Concomitant
Somnolence Hospitalization 5/16/2009 94 Male 5/5/2010 Other Health Professional Israel
Primary
Secondary
Concomitant
Somnolence Hospitalization 5/16/2009 94 Male 5/5/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Interacting
Suicidal Ideation Hospitalization Male 5/6/2010 Physician United Kingdom
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 6/3/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 9/30/2009 60 Male 205 lb 5/26/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 1/2/2007 69 Male 187 lb 6/7/2010 Lawyer United States
Primary
Secondary
Concomitant
Wheezing Other Serious 29 Female 125 lb 6/14/2010 United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Pain Hospitalization 7/7/2010 48 Male 148 lb 8/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pain Hospitalization 7/7/2010 48 Male 153 lb 8/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 12/14/2007 69 Male 187 lb 10/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Shock Hospitalization 12/19/2008 86 Male 141 lb 10/25/2010 Physician Taiwan, Province Of China
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 10/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 11/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 12/19/2008 86 Male 141 lb 11/5/2010 Other Health Professional United States
Primary
Concomitant
Wound Infection Other Serious 29 Female 276 lb 11/17/2010 United States
Primary
Concomitant
Liver Injury Life Threatening 12/16/2010 Physician Netherlands
Primary
Secondary
Concomitant
Myocardial Ischaemia Life Threatening 9/30/2010 67 Female 159 lb 12/17/2010 Consumer Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 29 Female 276 lb 12/15/2010 United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/1/2005 40 Male 12/29/2010 Other Health Professional United States
Primary
Concomitant
Hydronephrosis Other Serious 5/30/1996 48 Female 1/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Liver Injury Life Threatening 9/23/2010 1/12/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Leg Amputation Other Serious 29 Female 276 lb 1/5/2011 United States
Primary
Concomitant
Vomiting Hospitalization 12/14/2007 69 Male 187 lb 1/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Atrophy Other Serious 5/30/1996 48 Female 2/10/2011 United States
Primary
Secondary
Concomitant
Anxiety Other Serious 5/30/1996 48 Female 2/14/2011 Physician United States
Primary
Secondary
Concomitant
Spinal Compression Fracture Other Serious 1/17/2006 77 3/16/2011 United States
Primary
Concomitant
Diabetic Ketoacidosis Hospitalization 44 Female 243 lb 4/14/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Diabetic Ketoacidosis Hospitalization 44 Female 243 lb 4/14/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Diabetic Ketoacidosis Hospitalization 44 Female 243 lb 4/14/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Arrhythmia Other Serious 12/1/2007 54 Male 163 lb 4/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Myocardial Infarction Hospitalization 9/27/2010 67 Female 157 lb 5/3/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Varices Oesophageal Hospitalization 1/1/2010 54 Male 152 lb 5/23/2011 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Depression Other Serious 1/17/2006 77 6/1/2011 Physician United States
Primary
Concomitant
Varices Oesophageal Hospitalization 10/4/2010 54 Male 152 lb 6/6/2011 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Leukocytosis Hospitalization 1/1/2005 40 Male 6/7/2011 Lawyer United States
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 9/27/2010 67 Female 157 lb 6/16/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Death Death 2/2/2011 65 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Acute Myocardial Infarction Life Threatening 9/30/2010 67 Female 157 lb 7/20/2011 Consumer Germany
Primary
Secondary
Concomitant
Thrombocytopenia Death 12/1/2007 54 Male 163 lb 7/22/2011 Lawyer United States
Primary
Secondary
Concomitant
Cardiac Output Decreased Other Serious 12/1/2007 54 Male 163 lb 7/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Metastases To Bone Other Serious 1/1/2005 40 Male 8/1/2011 Lawyer United States
Primary
Concomitant
Breakthrough Pain Hospitalization 4/1/2011 52 Female 125 lb 8/19/2011 Consumer United States
Primary
Concomitant
Fall Other Serious 7/27/2011 94 Female 8/25/2011 Physician Spain
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 11/1/2009 61 Female 8/26/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Confusional State Hospitalization 9/14/2011 64 Female 163 lb 9/28/2011 Consumer Australia
Primary
Secondary
Concomitant
Metastases To Peritoneum Other Serious 11/1/2009 61 Female 9/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Confusional State Hospitalization 9/14/2011 64 Female 163 lb 10/5/2011 Physician Australia
Primary
Secondary
Concomitant
Headache Disability 6/17/2008 69 Female 150 lb 10/25/2011 Lawyer United States
Primary
Concomitant
Anaemia Life Threatening 69 Male 187 lb 10/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cholelithiasis Death 12/1/2007 54 Male 163 lb 11/16/2011 Lawyer United States
Primary
Secondary
Concomitant
Oliguria Death 8/8/2009 74 Female 130 lb 11/23/2011 Physician Japan
Primary
Secondary
Concomitant
Sinusitis Hospitalization 10/9/1996 23 Female 276 lb 11/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Muscle Spasms Hospitalization 11/1/2010 65 Female 12/5/2011 Consumer United States
Primary
Concomitant
Periarthritis Other Serious 1/1/2006 49 Female 204 lb 11/29/2011 Lawyer United States
Primary
Secondary
Concomitant
Multiple Sclerosis Relapse Hospitalization 10/1/2011 53 Female 12/8/2011 Consumer United States
Primary
Concomitant
Oral Pain Hospitalization 11/1/2010 65 Female 12/16/2011 Consumer United States
Primary
Concomitant
Intra-abdominal Haematoma Other Serious 11/1/2009 61 Female 12/21/2011 Physician United States
Primary
Secondary
Concomitant
Dysgeusia Other Serious 1/1/2011 84 Female 176 lb 12/22/2011 Consumer Brazil
Primary
Secondary
Concomitant
Vomiting Other Serious 11/1/2010 65 Female 12/20/2011 Consumer United States
Primary
Concomitant
Blood Chloride Increased Hospitalization 12/1/2011 74 Female 972 lb 12/28/2011 United States
Primary
Secondary
Concomitant
Nail Bed Inflammation Hospitalization 1/5/2012 67 Male 161 lb 1/10/2012 Physician Germany
Primary
Concomitant
Multiple Sclerosis Relapse Hospitalization 10/1/2011 53 Female 1/11/2012 Physician United States
Primary
Concomitant
Nail Bed Inflammation Hospitalization 1/5/2012 67 Male 161 lb 1/18/2012 Physician Germany
Primary
Concomitant
Family Stress Disability Male 1/20/2012 Lawyer United States
Primary
Secondary
Concomitant
Haematoma Disability 11/4/2011 75 Male 2/1/2012 Physician Germany
Primary
Concomitant
Herpes Zoster Infection Neurological Other Serious 3/17/2011 55 Male 2/6/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Oedema Peripheral Disability 11/4/2011 75 Male 2/7/2012 Physician Germany
Primary
Concomitant
Suicide Attempt Hospitalization 12/25/2011 74 Male 174 lb 2/21/2012 Consumer United States
Primary
Concomitant
Hypoglycaemia Hospitalization 12/25/2011 2/27/2012 Consumer Germany
Primary
Secondary
Concomitant
Hypoalbuminaemia Other Serious 8/8/2009 74 Female 130 lb 3/22/2012 Physician Japan
Primary
Secondary
Concomitant
Hypertension Hospitalization 12/22/2010 61 Male 141 lb 4/9/2012 Physician Japan
Primary
Concomitant
Hepatic Cirrhosis Death Female 74 lb 4/4/2012 Physician Japan
Primary
Concomitant
Memory Impairment Hospitalization 11/1/2010 65 Female 4/10/2012 Consumer United States
Primary
Concomitant
Herpes Zoster Infection Neurological Other Serious 3/17/2011 56 Male 5/7/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Inguinal Hernia, Obstructive Hospitalization 5/16/2012 71 Female 161 lb 6/4/2012 Physician Germany
Primary
Secondary
Concomitant
Gastric Ulcer Hospitalization 10/4/2010 54 Male 152 lb 6/11/2012 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Gastritis Erosive Hospitalization 7/1/2007 48 Female 130 lb 6/14/2012 Lawyer United States
Primary
Concomitant
Nail Bed Inflammation Hospitalization 1/5/2012 67 Male 161 lb 6/22/2012 Physician Germany
Primary
Concomitant
Disease Progression Hospitalization 7/5/2012 45 Female 7/24/2012 Pharmacist United States
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 12/25/2011 8/7/2012 Consumer Germany
Primary
Secondary
Concomitant
Embolism Hospitalization 1/17/2006 77 Female 8/15/2012 Lawyer United States
Primary
Concomitant
Anxiety Other Serious 1/17/2006 77 Female 8/17/2012 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 7/2009 Male 3/22/2013 Pharmacist Gb
Primary
Concomitant
Tardive Dyskinesia Other Serious Female 161 lb 10/8/2012 Lawyer Us
Primary
Concomitant
Herpes Zoster Infection Neurological Other Serious 3/17/2011 56 Male 7/19/2013 Consumer Us
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 4/2011 53 Female 125 lb 11/25/2013 Consumer Us
Primary
Concomitant
Suicide Attempt Hospitalization 12/25/2011 NotSpecified 4/8/2013 Consumer De
Primary
Secondary
Concomitant
Inguinal Hernia, Obstructive Hospitalization 5/16/2012 NotSpecified 5/7/2013 Physician De
Primary
Secondary
Concomitant
Failure To Thrive Hospitalization 2012 Male 148 lb 9/5/2012 Physician Us
Primary
Concomitant
Weight Increased Other Serious 10/24/2012 Other Health Professional Il
Primary
Concomitant
Mental Status Changes Death 8/24/2011 77 Male 11/8/2012 Physician Us
Primary
Concomitant
Pneumonia Aspiration Hospitalization 8/30/2011 77 Male 11/5/2012 Pharmacist Us
Primary
Concomitant
Cerebrovascular Accident Hospitalization 67 Male 200 lb 11/12/2012 Other Health Professional Us
Primary
Concomitant
Cerebrovascular Accident Other Serious 67 Male 205 lb 11/19/2012 Other Health Professional Us
Primary
Concomitant
Cerebrovascular Accident Other Serious 67 Male 207 lb 11/19/2012 Other Health Professional Us
Primary
Concomitant
Removal Of Ambulatory Peritoneal Catheter Hospitalization 9/20/2012 29 Female 123 lb 12/5/2012 Physician Kr
Primary
Secondary
Concomitant
Subdural Haematoma Death 7/25/2012 82 Male 181 lb 1/21/2013 Other Health Professional Us
Primary
Concomitant
Hospitalisation Hospitalization 4/3/2012 29 Female 1/28/2013 Pharmacist Ie
Primary
Concomitant
Syncope Other Serious 61 Female 140 lb 10/8/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Syncope Other Serious 61 Female 140 lb 10/10/2013 Consumer Gb
Primary
Secondary
Concomitant
Syncope Other Serious 61 Female 140 lb 10/16/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Syncope Other Serious 61 Female 140 lb 10/15/2013 Consumer Gb
Primary
Secondary
Concomitant
Musculoskeletal Pain Disability 4/26/2013 61 Female 123 lb 7/5/2013 Other Health Professional Gb
Primary
Concomitant
Peptic Ulcer Hospitalization 35 Female 9/4/2013 Physician Us
Primary
Concomitant
Interacting
Musculoskeletal Pain Disability 4/26/2013 61 Female 123 lb 7/15/2013 Physician Gb
Primary
Concomitant
White Blood Cell Count Increased Other Serious 5/31/2013 42 Female 10/28/2013 Other Health Professional Gb
Primary
Concomitant
Renal Failure Death Male 8/29/2013 Physician Us
Primary
Concomitant
Peptic Ulcer Hospitalization 35 Female 8/6/2013 Physician Us
Primary
Concomitant
Vomiting Hospitalization 35 Female 8/20/2013 Other Health Professional Us
Primary
Concomitant
Interacting
Drug Interaction Hospitalization 35 Female 8/21/2013 Other Health Professional Us
Primary
Concomitant
Interacting
Drug Interaction Hospitalization 35 Female 8/21/2013 Physician Us
Primary
Concomitant
Interacting
Drug Interaction Other Serious 35 Female 8/26/2013 Physician Us
Primary
Concomitant
Interacting
Metastases To Liver Other Serious 4/7/2012 64 Female 8/27/2013 Consumer Us
Primary
Concomitant
Peptic Ulcer Hospitalization 35 Female 8/30/2013 Other Health Professional Us
Primary
Concomitant
Interacting
Heart Rate Increased Other Serious 9/6/2013 58 Male 9/11/2013 Consumer Us
Primary
Concomitant
Neutropenia Other Serious 8/15/2012 58 Male 6/25/2013 Us
Primary
Secondary
Concomitant
Weight Decreased Death 11/2009 62 Female 12/21/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 1/17/2006 78 Female 11/9/2012 Consumer Us
Primary
Concomitant

Drug Data