Lactulose combined with Warfarin Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Abdominal Haematoma Life Threatening 12/6/2005 81 Female 1/23/2006 Norway
Primary
Secondary
Concomitant
Vomiting Other Serious 8/1/2001 76 Female 99 lb 2/24/2006 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 8/1/2001 76 Female 99 lb 3/2/2006 Physician United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 12/26/2004 77 Male 214 lb 3/29/2006 Pharmacist United States
Primary
Concomitant
Infected Skin Ulcer Hospitalization 4/1/2006 59 Male 109 lb 5/23/2006 Physician United States
Primary
Concomitant
Ulcer Haemorrhage Other Serious 2/28/2005 62 Female 179 lb 5/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hypoglycaemia Hospitalization 5/1/2006 70 Female 130 lb 6/15/2006 Consumer United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 10/11/2003 Female 170 lb 7/7/2006 Physician United States
Primary
Secondary
Concomitant
Haemoptysis 71 Female 136 lb 7/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Chronic Hospitalization 11/18/2004 51 Female 10/25/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Tremor Hospitalization 8/28/2006 Male 10/23/2006 Pharmacist United States
Primary
Concomitant
Headache 6/8/2006 Male 10/30/2006 Consumer United States
Primary
Concomitant
Memory Impairment Other Serious 11/6/2006 81 Female 11/6/2006 Pharmacist United States
Primary
Concomitant
Tachycardia Hospitalization 5/2/2003 55 Male 238 lb 11/6/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 2/10/2006 43 Male 11/8/2006 Consumer Canada
Primary
Concomitant
Hyperammonaemia Disability 1/1/2006 63 Female 11/16/2006 Physician Japan
Primary
Concomitant
Hyperammonaemia Other Serious 1/1/2006 63 Female 11/21/2006 Physician Japan
Primary
Concomitant
Syncope Hospitalization 10/11/2006 69 Male 183 lb 12/4/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Required Intervention 7/23/2006 68 Female 148 lb 7/28/2006 Pharmacist United States
Primary
Secondary
Concomitant
Paraesthesia Oral 71 Female 136 lb 10/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Malaise Other Serious 1/18/2007 Female 1/19/2007 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 12/27/2006 84 Male 1/24/2007 United Kingdom
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 12/30/2006 78 Male 242 lb 1/18/2007 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Death 10/1/2006 87 Female 117 lb 3/6/2007 Physician Germany
Primary
Concomitant
Syncope Hospitalization 10/11/2006 Male 183 lb 3/14/2007 United Kingdom
Primary
Concomitant
Pain Hospitalization 2/15/2007 85 Female 99 lb 3/23/2007 United Kingdom
Primary
Concomitant
Sudden Death Death 10/27/2004 52 Female 174 lb 4/12/2007 Physician Australia
Primary
Concomitant
Respiratory Arrest Death 10/1/2006 87 Female 117 lb 4/12/2007 Other Health Professional Germany
Primary
Concomitant
Nausea Death 4/3/2007 41 Male 152 lb 5/2/2007 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 2/1/2007 63 Male 302 lb 4/30/2007 United Kingdom
Primary
Secondary
Concomitant
Serum Ferritin Increased Death 3/23/2006 73 Male 6/7/2007 Physician United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Death 1/1/2004 43 Male 115 lb 8/15/2007 Other Health Professional United States
Primary
Concomitant
Death Death 5/1/2007 Male 183 lb 9/5/2007 United States
Primary
Concomitant
General Physical Health Deterioration Hospitalization 78 Male 8/27/2007 Physician Belgium
Primary
Secondary
Concomitant
Death Death 5/1/2007 Male 183 lb 9/11/2007 United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Death 1/1/2004 43 Male 115 lb 10/8/2007 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 6/23/2007 67 Male 223 lb 10/23/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Treatment Noncompliance 6/8/2006 69 Male 10/25/2007 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 6/27/2007 10/31/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Death 5/23/2007 Male 183 lb 11/2/2007 United States
Primary
Concomitant
Proteinuria Death 1/9/2007 Female 235 lb 11/7/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Extradural Haematoma Life Threatening 10/24/2007 42 Male 11/16/2007 Pharmacist United States
Primary
Concomitant
Proteinuria Death 1/1/2007 52 Female 235 lb 11/29/2007 Other Health Professional United Kingdom
Primary
Secondary
Interacting
Proteinuria Death 1/9/2007 Female 235 lb 12/3/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Death 10/1/2006 87 Female 117 lb 11/30/2007 Consumer Germany
Primary
Concomitant
Pulmonary Oedema Death 10/1/2006 87 Female 117 lb 12/21/2007 Consumer Germany
Primary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization 7/25/2007 87 Female 192 lb 11/5/2007 Pharmacist United States
Primary
Secondary
Concomitant
Death Death 5/23/2007 Male 183 lb 2/5/2008 United States
Primary
Concomitant
Neuropathy Peripheral Death 1/1/2006 Male 175 lb 2/6/2008 Physician United States
Primary
Concomitant
Urethritis Hospitalization 1/30/2008 63 Male 2/4/2008 Norway
Primary
Concomitant
Pulmonary Congestion Other Serious 7/30/2007 78 Male 236 lb 3/6/2008 Physician United Kingdom
Primary
Concomitant
Oesophageal Cancer Metastatic Hospitalization 3/5/2008 69 Male 174 lb 3/11/2008 United States
Primary
Concomitant
Type 1 Diabetes Mellitus Hospitalization 1/1/2002 27 Female 299 lb 3/24/2008 Physician United States
Primary
Concomitant
Peritonitis Hospitalization 3/15/2008 71 Male 201 lb 4/10/2008 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 4/2/2008 85 Male 187 lb 4/17/2008 Pharmacist United States
Primary
Secondary
Concomitant
Swollen Tongue Hospitalization 4/5/2008 64 Female 146 lb 4/29/2008 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Hospitalization 10/11/2006 Male 183 lb 6/12/2008 United Kingdom
Primary
Concomitant
Urethritis Hospitalization 1/30/2008 63 Male 6/5/2008 Norway
Primary
Concomitant
Death Death 5/23/2007 Male 183 lb 6/18/2008 United States
Primary
Concomitant
Vomiting Other Serious 5/8/2008 76 Female 121 lb 6/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sensation Of Foreign Body Other Serious 1/1/2007 76 Female 6/25/2008 Consumer United States
Primary
Concomitant
Carcinoma In Situ Of Skin Other Serious 4/4/2007 Female 137 lb 7/29/2008 Other Health Professional United Kingdom
Primary
Concomitant
Proteinuria Death 1/9/2007 Female 235 lb 8/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Proteinuria Other Serious 1/1/2007 52 Female 235 lb 8/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Proteinuria Other Serious 1/1/2007 Female 235 lb 8/14/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Proteinuria Other Serious 1/1/2007 Female 235 lb 9/2/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 5/1/2008 76 Female 9/3/2008 Other Health Professional Sweden
Primary
Concomitant
Renal Failure Chronic Hospitalization 11/18/2004 51 Female 9/15/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Other Serious 8/23/2008 89 Male 132 lb 9/16/2008 Other Health Professional United Kingdom
Primary
Concomitant
Coronary Artery Occlusion Hospitalization 7/1/2008 Female 212 lb 9/18/2008 United States
Primary
Concomitant
Toxic Skin Eruption Hospitalization 2/5/2008 Male 10/16/2008 Consumer Germany
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 11/1/2007 63 Male 179 lb 11/10/2008 Pharmacist United States
Primary
Concomitant
Gastric Perforation Life Threatening 7/19/2008 Male 12/2/2008 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/26/2007 65 Male 161 lb 12/11/2008 Physician Japan
Primary
Secondary
Concomitant
Gastric Perforation Life Threatening 7/19/2008 Male 12/30/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Left Ventricular Dysfunction Other Serious 2/1/2008 60 Male 269 lb 1/16/2009 Other Health Professional United States
Primary
Concomitant
Left Ventricular Dysfunction Other Serious 2/1/2008 60 Male 269 lb 1/19/2009 Other Health Professional United States
Primary
Concomitant
Death Other Serious 70 1/28/2009 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Failure Other Serious 11/1/2007 63 Male 179 lb 2/2/2009 Pharmacist United States
Primary
Concomitant
Feeling Jittery 2/2/2009 Female 132 lb 2/4/2009 Physician United States
Primary
Concomitant
Metastases To Liver Other Serious Female 145 lb 4/16/2009 Canada
Primary
Concomitant
Proteinuria Other Serious 1/1/2007 Female 235 lb 4/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Urinary Tract Infection Hospitalization 1/7/2009 4/23/2009 Physician Sweden
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2007 54 Male 5/7/2009 Physician United Kingdom
Primary
Concomitant
Gastric Disorder 3/17/2009 Male 5/27/2009 United States
Primary
Concomitant
Urinoma Hospitalization 11/13/2004 Male 163 lb 6/23/2009 Physician Canada
Primary
Secondary
Concomitant
Vaginal Haemorrhage Required Intervention 4/14/2009 44 Female 214 lb 4/15/2009 Pharmacist United States
Primary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization 6/21/2009 74 Female 73 lb 7/8/2009 Pharmacist United States
Primary
Concomitant
Tachycardia Hospitalization 63 Male 7/23/2009 United States
Primary
Concomitant
Tachycardia Hospitalization 63 Male 8/5/2009 United States
Primary
Concomitant
Sepsis Other Serious 11/1/2007 63 Male 179 lb 8/28/2009 Pharmacist United States
Primary
Concomitant
Hepatocellular Injury Other Serious 7/10/2009 69 Female 8/31/2009 Other Health Professional United Kingdom
Primary
Concomitant
Tachycardia Hospitalization 63 Male 178 lb 9/3/2009 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 79 Female 9/8/2009 United States
Primary
Concomitant
Gastric Perforation Life Threatening 7/19/2008 Male 11/12/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 10/21/2008 57 Male 174 lb 12/28/2009 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 68 Male 1/4/2010 Other Health Professional United Kingdom
Primary
Concomitant
Acute Pulmonary Oedema Hospitalization 12/27/2009 79 Male 1/7/2010 Consumer United States
Primary
Secondary
Concomitant
Acute Pulmonary Oedema Hospitalization 12/27/2009 79 Male 1/15/2010 Consumer United States
Primary
Secondary
Concomitant
Proteinuria Other Serious 1/1/2007 Female 235 lb 1/29/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
White Blood Cell Count Increased Death 11/6/2009 Female 163 lb 2/12/2010 United Kingdom
Primary
Concomitant
Skin Tightness Death 1/1/2004 43 Male 115 lb 2/17/2010 United States
Primary
Concomitant
Wheezing Other Serious 5/1/2003 Male 2/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 Male 3/4/2010 Lawyer United States
Primary
Concomitant
Wheezing Other Serious 5/1/2003 Male 3/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 12/14/2007 69 Male 3/4/2010 Lawyer United States
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 12/27/2009 79 Male 159 lb 3/5/2010 Consumer United States
Primary
Secondary
Concomitant
Death Hospitalization Female 3/5/2010 Physician Canada
Primary
Concomitant
Peripheral Ischaemia Life Threatening 10/1/2008 Female 119 lb 3/12/2010 Physician Brazil
Primary
Secondary
Concomitant
Wheezing Other Serious 4/1/2003 Male 3/19/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/1/2004 Female 140 lb 3/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 73 Female 3/25/2010 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 88 Female 4/12/2010 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 10/1/2004 54 Female 140 lb 4/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/1/2004 54 Female 140 lb 4/30/2010 United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 3/3/2010 50 Female 210 lb 3/4/2010 Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 84 Male 5/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 84 Male 5/13/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Weight Decreased Hospitalization 84 Male 5/13/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Weight Decreased Hospitalization 84 Male 5/12/2010 Other Health Professional
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 6/3/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/2/2007 69 Male 187 lb 6/7/2010 Lawyer United States
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 12/27/2009 79 Male 159 lb 6/7/2010 Consumer United States
Primary
Secondary
Concomitant
Infective Exacerbation Of Chronic Obstructive Airways Disease Hospitalization 12/27/2009 79 Male 159 lb 6/28/2010 Consumer United States
Primary
Secondary
Concomitant
Hypoaesthesia Other Serious 5/30/2010 63 Male 7/7/2010 Other Health Professional United Kingdom
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Dyspnoea Other Serious 5/27/2010 68 Male 7/22/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vision Blurred Other Serious 10/1/2007 69 Female 157 lb 7/22/2010 Lawyer United States
Primary
Concomitant
Tinea Versicolour Hospitalization 3/28/2010 82 Male 7/23/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 7/21/2010 68 Male 239 lb 7/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2008 54 Male 8/17/2010 Lawyer United States
Primary
Concomitant
Vision Blurred Other Serious 10/1/2007 69 Female 157 lb 9/16/2010 Lawyer United States
Primary
Concomitant
Medical Device Complication Other Serious 1/1/2008 85 Male 192 lb 9/30/2010 Other Health Professional United States
Primary
Concomitant
Varices Oesophageal Other Serious 8/1/2010 62 Male 10/1/2010 Other Health Professional United States
Primary
Concomitant
Vascular Graft Occlusion Other Serious 2/1/2008 53 Male 203 lb 10/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 12/14/2007 69 Male 187 lb 10/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2008 54 Male 10/13/2010 Other Health Professional United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 10/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 11/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Wheezing Other Serious 4/1/2003 79 Male 11/25/2010 United States
Primary
Secondary
Concomitant
Weight Increased 9/1/2009 49 Female 12/10/2010 Consumer Australia
Primary
Concomitant
International Normalised Ratio Increased Other Serious 85 Female 165 lb 12/17/2010 Pharmacist Canada
Primary
Secondary
Concomitant
Confusional State Hospitalization 10/5/2010 78 Female 12/20/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Wheezing Other Serious 4/1/2003 79 Male 12/23/2010 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/14/2007 69 Male 187 lb 1/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Malaise Death 1/1/2008 54 Male 2/15/2011 Lawyer United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 1/1/2002 27 Female 298 lb 2/25/2011 United States
Primary
Concomitant
Cytomegalovirus Viraemia Hospitalization 12/30/2009 22 Male 141 lb 3/29/2011 Pharmacist United States
Primary
Concomitant
Multiple Sclerosis Death 1/12/2011 84 Female 110 lb 4/4/2011 Consumer Switzerland
Primary
Concomitant
Congestive Cardiomyopathy Other Serious 4/1/2003 79 Male 4/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data