Lactulose combined with Velcade

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sepsis Hospitalization 1/1/2005 63 Male 3/6/2006 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/26/2005 64 Male 3/7/2006 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Death 2/22/2006 76 Female 4/10/2006 Physician United Kingdom
Primary
Concomitant
Neutropenia Hospitalization 4/28/2006 58 Male 203 lb 5/16/2006 Physician Germany
Primary
Secondary
Concomitant
Hiccups Hospitalization 1/29/2006 61 Unknown 5/22/2006 Physician Netherlands
Primary
Secondary
Concomitant
Multiple Myeloma Death 10/12/2004 67 Male 250 lb 5/31/2006 Physician Canada
Primary
Concomitant
Disease Progression Death 10/12/2004 67 Male 250 lb 6/21/2006 Physician Canada
Primary
Concomitant
Leukopenia Other Serious 5/12/2006 62 Female 185 lb 6/29/2006 Physician Germany
Primary
Secondary
Concomitant
Urethral Haemorrhage Other Serious 5/4/2006 59 Male 144 lb 6/29/2006 Physician Germany
Primary
Secondary
Concomitant
Leukopenia Other Serious 5/12/2006 62 Female 185 lb 7/13/2006 Physician Germany
Primary
Secondary
Concomitant
Urethral Haemorrhage Other Serious 5/4/2006 59 Male 144 lb 8/3/2006 Physician Germany
Primary
Secondary
Concomitant
Extravasation Hospitalization 6/9/2006 58 8/10/2006 Physician Germany
Primary
Secondary
Concomitant
Extravasation Hospitalization 6/9/2006 58 8/31/2006 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 8/11/2006 Male 174 lb 9/7/2006 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/28/2006 58 Male 203 lb 9/7/2006 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 8/11/2006 Male 174 lb 9/29/2006 Physician Germany
Primary
Secondary
Concomitant
Proctalgia Other Serious 10/6/2006 70 Male 172 lb 10/24/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Tachycardia Hospitalization 5/2/2003 55 Male 238 lb 11/6/2006 Physician United States
Primary
Secondary
Concomitant
Perianal Abscess Other Serious 10/6/2006 70 Male 172 lb 11/6/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Urethral Haemorrhage Other Serious 10/30/2006 Male 181 lb 12/4/2006 Physician Czech Republic
Primary
Concomitant
Pulmonary Embolism Other Serious 11/30/2006 73 Male 194 lb 2/6/2007 United Kingdom
Primary
Concomitant
Transfusion Required Intervention 8/5/2006 65 Female 91 lb 5/10/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/15/2006 51 Male 5/11/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/15/2006 52 Male 5/18/2007 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 10/5/2006 52 Male 5/21/2007 Physician United States
Primary
Secondary
Concomitant
Urethral Haemorrhage Other Serious 5/4/2006 59 Male 144 lb 7/2/2007 Physician Germany
Primary
Secondary
Concomitant
Ankle Fracture Hospitalization 12/4/2004 61 Female 5/24/2007 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 11/15/2007 Female 12/6/2007 Pharmacist United States
Primary
Concomitant
Transaminases Increased Other Serious 2/21/2005 50 Male 115 lb 1/25/2008 Physician Poland
Primary
Concomitant
Pneumonia Hospitalization 11/1/2007 54 Female 12/7/2007 Other Health Professional United States
Primary
Concomitant
Syncope Vasovagal Hospitalization 6/26/2006 59 Female 240 lb 4/15/2008 Physician United States
Primary
Secondary
Concomitant
Syncope Vasovagal Hospitalization 6/26/2006 59 Female 240 lb 4/8/2008 Physician United States
Primary
Secondary
Concomitant
Cytomegalovirus Infection Hospitalization 6/30/2006 59 Female 240 lb 4/16/2008 Physician United States
Primary
Secondary
Concomitant
Syncope Vasovagal Hospitalization 6/26/2006 59 Female 240 lb 4/25/2008 Physician United States
Primary
Secondary
Concomitant
Leukopenia Other Serious 5/12/2006 62 Female 185 lb 4/29/2008 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/28/2006 58 Male 203 lb 4/30/2008 Physician Germany
Primary
Secondary
Concomitant
Syncope Vasovagal Hospitalization 6/26/2006 59 Female 240 lb 5/13/2008 Physician United States
Primary
Secondary
Concomitant
Rectal Spasm Hospitalization 6/1/2008 59 Female 114 lb 6/6/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Enteritis Hospitalization 6/30/2006 59 Female 240 lb 6/4/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/27/2008 51 Female 166 lb 7/1/2008 Physician United States
Primary
Secondary
Concomitant
Urethral Haemorrhage Other Serious 5/4/2006 59 Male 144 lb 7/3/2008 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/27/2008 51 Female 166 lb 7/15/2008 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia 8/11/2008 Male 8/12/2008 Pharmacist United States
Primary
Concomitant
Pancytopenia Other Serious 1/1/2008 Male 9/26/2008 Consumer United States
Primary
Concomitant
Tachycardia Hospitalization 11/26/2007 65 Male 161 lb 10/12/2008 Physician Japan
Primary
Secondary
Concomitant
Pancytopenia Other Serious 1/1/2008 Male 10/17/2008 Other Health Professional United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1991 Male 188 lb 10/29/2008 United States
Primary
Secondary
Concomitant
Troponin Increased Life Threatening 6/11/2008 59 Male 174 lb 11/10/2008 Physician Germany
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 8/22/2008 66 Male 185 lb 11/14/2008 Physician Australia
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1991 Male 188 lb 11/21/2008 United States
Primary
Secondary
Concomitant
Memory Impairment Hospitalization 1/21/2002 57 Male 174 lb 11/24/2008 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 6/11/2008 59 Male 174 lb 11/21/2008 Physician Germany
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 8/22/2008 66 Male 185 lb 11/25/2008 Physician Australia
Primary
Secondary
Concomitant
Stem Cell Transplant 5/28/2003 74 Female 167 lb 11/26/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/26/2007 65 Male 161 lb 12/11/2008 Physician Japan
Primary
Secondary
Concomitant
X-ray Abnormal Hospitalization 8/22/2008 66 Male 185 lb 1/28/2009 Physician Australia
Primary
Secondary
Concomitant
Wheelchair User Hospitalization 12/15/2008 80 Male 136 lb 2/3/2009 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 1/13/2009 59 Male 2/27/2009 Belgium
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/30/2008 38 Female 139 lb 3/9/2009 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/13/2009 59 Male 3/25/2009 Belgium
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 12/15/2008 80 Male 136 lb 3/26/2009 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/13/2009 59 Male 4/1/2009 Belgium
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/13/2009 59 Male 4/28/2009 Belgium
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/13/2009 60 Male 5/4/2009 Belgium
Primary
Secondary
Concomitant
Lymphopenia Other Serious 4/27/2009 Male 176 lb 5/12/2009 Physician United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1991 Male 188 lb 5/20/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/13/2009 60 Male 5/29/2009 Belgium
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/13/2009 60 Male 6/12/2009 Belgium
Primary
Secondary
Concomitant
Tic Other Serious 4/3/2008 61 Male 201 lb 6/19/2009 Physician United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 8/22/2009 Female 201 lb 9/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/13/2009 60 Male 9/10/2009 Belgium
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 1/6/2009 68 Female 202 lb 9/14/2009 Physician United States
Primary
Concomitant
Staphylococcal Infection Life Threatening 1/13/2009 60 Male 9/15/2009 Belgium
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 8/22/2009 Female 191 lb 9/25/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pyelonephritis Hospitalization 8/22/2009 52 Female 201 lb 9/21/2009 Physician United States
Primary
Secondary
Concomitant
Death Death 4/1/2009 Female 9/30/2009 Pharmacist United States
Primary
Secondary
Concomitant
Pyelonephritis Hospitalization 8/22/2009 52 Female 201 lb 10/1/2009 Physician United States
Primary
Secondary
Concomitant
Vitamin K Deficiency Hospitalization 8/22/2008 66 Male 185 lb 10/2/2009 Physician Australia
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/13/2009 60 Male 10/6/2009 Belgium
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/13/2009 60 Male 10/22/2009 Belgium
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/13/2009 60 Male 11/12/2009 Belgium
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/13/2009 60 Male 11/17/2009 Belgium
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 1/13/2009 60 Male 12/8/2009 Belgium
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/13/2009 60 Male 12/23/2009 Physician Belgium
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/13/2009 60 Male 12/31/2009 Belgium
Primary
Secondary
Concomitant
Disease Progression Hospitalization 1/14/2009 2/8/2010 Physician France
Primary
Concomitant
Vertigo Other Serious 1/1/2001 Female 2/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Disease Progression Hospitalization 1/14/2009 2/23/2010 Physician France
Primary
Concomitant
Neutropenia Hospitalization 7/3/2009 69 Male 172 lb 2/11/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 7/3/2009 69 Male 172 lb 2/11/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 4/27/2009 3/3/2010 Physician France
Primary
Concomitant
Ventricular Tachycardia Other Serious 8/6/2009 68 Female 202 lb 3/9/2010 Physician United States
Primary
Concomitant
Vertigo Other Serious 1/1/2001 Female 3/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2002 56 Female 195 lb 4/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vertigo Other Serious 1/1/2001 67 Female 4/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2002 56 Female 195 lb 5/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vertigo Other Serious 1/1/2001 67 Female 5/21/2010 United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 5/11/2006 35 Female 6/2/2010 Physician United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 1/1/2001 67 Female 6/11/2010 United States
Primary
Secondary
Concomitant
Vaginal Ulceration Other Serious 2/1/2010 69 Female 6/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1991 54 Male 188 lb 6/30/2010 Consumer United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 1/1/2001 67 Female 7/6/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/1991 54 Male 188 lb 7/15/2010 Consumer United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 1/1/2001 67 Female 7/22/2010 United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 12/30/2008 8/3/2010 Physician Netherlands
Primary
Concomitant
Vomiting Other Serious 1/1/1991 54 Male 188 lb 8/5/2010 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 5/1/2009 8/18/2010 Physician France
Primary
Concomitant
Thrombocytopenia Life Threatening 10/10/2008 8/19/2010 Physician France
Primary
Concomitant
Vomiting Other Serious 1/1/1991 54 Male 188 lb 8/20/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2003 46 Male 178 lb 9/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Ineffective Life Threatening 9/24/2010 Pharmacist United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 1/1/1991 54 Male 188 lb 9/30/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2003 46 Male 178 lb 10/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2003 46 Male 178 lb 10/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2002 65 Male 188 lb 10/18/2010 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/23/2010 85 Male 121 lb 10/22/2010 Physician Belgium
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/23/2010 10/25/2010 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 9/3/2010 11/5/2010 Physician France
Primary
Secondary
Concomitant
Oesophagitis Ulcerative Hospitalization 9/3/2010 70 Male 187 lb 11/5/2010 Physician France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2003 46 Male 179 lb 11/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2002 65 Male 188 lb 11/8/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2003 46 Male 179 lb 11/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2002 65 Male 188 lb 11/18/2010 United States
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 9/3/2010 11/23/2010 Physician France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2002 65 Male 188 lb 11/24/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2002 65 Male 188 lb 11/26/2010 United States
Primary
Secondary
Concomitant
Renal Failure Death 1/1/2009 79 Female 12/14/2010 Pharmacist United States
Primary
Secondary
Concomitant
Liver Injury Life Threatening 12/16/2010 Physician Netherlands
Primary
Secondary
Concomitant
Light Chain Disease Death 1/1/2009 79 Female 1/6/2011 Physician United States
Primary
Secondary
Concomitant
Liver Injury Life Threatening 9/23/2010 1/12/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Hypotension Hospitalization 9/3/2010 2/7/2011 Consumer France
Primary
Secondary
Concomitant
Cerebral Ischaemia Other Serious 12/18/2006 67 Male 2/14/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Epilepsy Hospitalization 2/1/2011 3/4/2011 Physician France
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 3/9/2011 3/25/2011 Physician Germany
Primary
Concomitant
Hypokalaemia Hospitalization 2/19/2011 4/4/2011 Physician France
Primary
Secondary
Concomitant
Radiculopathy Hospitalization 2/18/2011 46 Male 180 lb 4/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hypoaesthesia Hospitalization 2/26/2011 86 Male 179 lb 4/15/2011 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/7/2009 79 Male 4/13/2011 United Kingdom
Primary
Secondary
Concomitant
Hepatic Encephalopathy Hospitalization 12/24/2010 5/4/2011 Other Health Professional France
Primary
Secondary
Concomitant
Breast Cancer Metastatic Hospitalization 2/19/2011 5/11/2011 Other Health Professional France
Primary
Secondary
Concomitant
Jaundice Cholestatic Death 3/19/2011 70 Female 94 lb 5/12/2011 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Feeling Abnormal Hospitalization 1/1/2001 67 Female 5/13/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Death 12/1/2008 49 Female 5/31/2011 Physician United States
Primary
Concomitant
Death Death 2/1/2011 63 Female 6/3/2011 Pharmacist United States
Primary
Concomitant
Hypercalcaemia Death 12/1/2008 49 Female 6/6/2011 Physician United States
Primary
Concomitant
Pleural Fibrosis Other Serious 12/18/2006 67 Male 6/13/2011 Physician United States
Primary
Secondary
Concomitant
Hypertension Life Threatening 1/13/2009 60 Male 6/15/2011 Other Health Professional Belgium
Primary
Secondary
Concomitant
Bronchopneumonia Hospitalization 1/13/2009 60 Male 6/17/2011 Physician Belgium
Primary
Secondary
Concomitant
Fatigue Hospitalization 9/6/2010 6/27/2011 Physician Germany
Primary
Secondary
Concomitant
Oral Discharge Hospitalization 1/1/2001 67 Female 6/28/2011 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data