Lactulose combined with Tramadol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rales Life Threatening 11/11/2005 85 Female 1/23/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 12/6/2005 69 Female 148 lb 1/27/2006 United Kingdom
Primary
Secondary
Concomitant
Osteoporosis Hospitalization 2/15/2004 Female 112 lb 2/9/2006 United Kingdom
Primary
Concomitant
Neutropenic Sepsis Hospitalization 12/6/2005 69 Female 148 lb 3/29/2006 United Kingdom
Primary
Secondary
Concomitant
Myoclonus Hospitalization 4/23/2006 Male 7/18/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Hospitalization 1/9/2006 1/23/2009 Germany
Primary
Concomitant
Benign Intracranial Hypertension Hospitalization 3/13/2009 3/30/2009 United Kingdom
Primary
Secondary
Concomitant
Benign Intracranial Hypertension Hospitalization 3/13/2009 36 6/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Social Avoidant Behaviour Death 80 Female 7/20/2009 United States
Primary
Concomitant
Benign Intracranial Hypertension Hospitalization 3/13/2009 36 7/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Neutropenia Hospitalization 6/6/2007 Male 8/10/2009 Physician Chile
Primary
Concomitant
Benign Intracranial Hypertension Hospitalization 3/13/2009 36 9/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Life Threatening 2/9/2009 Male 172 lb 10/7/2009 Germany
Primary
Secondary
Concomitant
Septic Shock Hospitalization 12/1/2007 47 10/8/2009 Physician Belgium
Primary
Concomitant
Wheezing Hospitalization 9/7/2008 53 Male 243 lb 10/27/2009 United States
Primary
Concomitant
General Physical Health Deterioration Death 11/17/2009 Female 11/24/2009 Physician Netherlands
Primary
Concomitant
Varices Oesophageal Hospitalization 1/1/2009 Female 1/5/2010 United States
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 9/29/2009 59 Female 230 lb 1/13/2010 Pharmacist United States
Primary
Concomitant
Interacting
General Physical Health Deterioration Life Threatening 11/13/2009 Female 1/25/2010 Physician Netherlands
Primary
Concomitant
White Blood Cell Count Increased Death 11/6/2009 Female 163 lb 2/12/2010 United Kingdom
Primary
Concomitant
Infection Hospitalization Male 2/17/2010 Consumer United States
Primary
Concomitant
Cellulitis Hospitalization Male 2/19/2010 Physician United States
Primary
Concomitant
Urinary Retention Hospitalization 11/13/2009 Male 153 lb 3/23/2010 Physician Belgium
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2001 45 Male 5/4/2010 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 12/29/2009 75 Male 5/4/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myalgia Hospitalization 3/20/2010 84 Female 209 lb 5/20/2010 Other Health Professional
Primary
Concomitant
Blood Urea Abnormal Hospitalization 5/19/2010 66 Male 6/1/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 5/19/2010 66 Male 6/10/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Subdural Haemorrhage Other Serious 2/12/2010 70 Male 6/14/2010 Other Health Professional Ireland
Primary
Secondary
Concomitant
Weight Decreased Other Serious 73 Female 6/25/2010 United States
Primary
Concomitant
Thrombocytopenia Other Serious 12/29/2009 75 Male 7/7/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 73 Female 7/2/2010 United States
Primary
Concomitant
Proteinuria Hospitalization 12/18/2009 68 Female 184 lb 7/13/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 3/1/2008 80 Male 7/21/2010 Lawyer United States
Primary
Concomitant
Thrombocytopenia Life Threatening 5/1/2009 8/18/2010 Physician France
Primary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 5/19/2010 66 Male 8/20/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Proteinuria Hospitalization 12/18/2009 68 Female 184 lb 9/15/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 3/1/2008 80 Male 9/17/2010 Lawyer United States
Primary
Secondary
Concomitant
Proteinuria Hospitalization 12/18/2009 68 Female 184 lb 9/28/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/19/2010 66 Male 10/11/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Synovitis Other Serious 6/1/2010 51 Female 223 lb 10/11/2010 Physician United Kingdom
Primary
Concomitant
Syncope Hospitalization 3/17/2009 78 Male 11/1/2010 Physician Germany
Primary
Secondary
Concomitant
Wheezing Other Serious 1/1/2009 34 Female 11/1/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wound Complication Hospitalization Female 181 lb 12/23/2010 Pharmacist
Primary
Concomitant
Malaise Hospitalization 1/1/2009 34 Female 1/7/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Lethargy Death 10/18/2007 40 Female 227 lb 2/15/2011 Lawyer United States
Primary
Concomitant
Refusal Of Treatment By Patient Death 3/9/2011 28 Female 205 lb 3/18/2011 Pharmacist United States
Primary
Concomitant
Lethargy Other Serious 1/1/2007 40 Female 227 lb 3/29/2011 Other Health Professional United States
Primary
Concomitant
Prostatic Specific Antigen Increased Other Serious 10/4/2004 57 Male 212 lb 3/30/2011 Other Health Professional United States
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 1/1/2003 67 Female 218 lb 3/30/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Multiple Myeloma Death 1/28/2011 75 Male 4/26/2011 Pharmacist United States
Primary
Concomitant
Heparin-induced Thrombocytopenia Death 2/12/2010 70 Male 5/5/2011 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Aggression Hospitalization 8/1/2008 56 Female 1/17/2012 Lawyer United States
Primary
Concomitant
Loss Of Consciousness Other Serious 8/1/2008 56 Female 2/3/2012 Lawyer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 8/18/2011 66 Male 239 lb 3/7/2012 Physician United States
Primary
Secondary
Concomitant
Contraindication To Surgery Hospitalization 8/1/2011 67 Male 198 lb 4/19/2012 Other Health Professional New Zealand
Primary
Concomitant
Chronic Hepatic Failure Disability 3/1/2012 46 Female 184 lb 5/2/2012 Consumer United States
Primary
Concomitant
Ascites Hospitalization 5/23/2012 49 Female 127 lb 5/30/2012 Physician Hong Kong
Primary
Concomitant
Chronic Hepatic Failure Other Serious 3/1/2012 46 Female 184 lb 6/1/2012 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Disability 3/1/2012 46 Female 184 lb 6/11/2012 Other Health Professional United States
Primary
Concomitant
Sleep Disorder Other Serious 7/26/2012 54 Female 198 lb 8/16/2012 Physician United Kingdom
Primary
Concomitant
Death Death 2/19/2011 82 Female 4/19/2013 Consumer Country Not Specified
Primary
Concomitant
Tardive Dyskinesia Other Serious Female 161 lb 10/8/2012 Lawyer Us
Primary
Concomitant
Vomiting Other Serious Female 117 lb 10/19/2012 Lawyer Us
Primary
Concomitant
Intestinal Obstruction Death 1/22/2012 98 Female 10/1/2012 Physician Gb
Primary
Concomitant
Non-small Cell Lung Cancer Death 5/23/2012 49 Female 127 lb 12/19/2012 Physician Hk
Primary
Concomitant
Thrombocytopenia Other Serious 6/2012 Male 227 lb 9/10/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Respiratory Depression Death 8/19/2012 64 Female 101 lb 10/19/2012 Physician In
Primary
Concomitant
Haemorrhoidal Haemorrhage Hospitalization 6/22/2010 36 Male 9/7/2012 Physician Au
Primary
Concomitant
Renal Tubular Necrosis Hospitalization 8/2012 Male 229 lb 9/14/2012 Physician Us
Primary
Secondary
Concomitant
Throat Tightness 47 Male 9/20/2012 Us
Primary
Concomitant
Urinary Tract Infection Hospitalization 8/17/2011 67 Male 186 lb 10/10/2012 Physician Ie
Primary
Concomitant
Respiratory Failure Death 9/21/2012 75 Female 123 lb 11/5/2012 Physician Hk
Primary
Concomitant
Gastric Haemorrhage Hospitalization 10/15/2012 70 Male 243 lb 6/6/2013 Physician Za
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 9/20/2012 57 Female 11/9/2012 Pharmacist Gb
Primary
Concomitant
Death Death 10/8/2012 65 Female 129 lb 11/19/2012 Physician Hk
Primary
Concomitant
Haematuria Hospitalization 10/24/2012 67 Male 157 lb 11/16/2012 Physician Hk
Primary
Concomitant
Spinal Osteoarthritis Hospitalization 10/20/2006 60 Male 148 lb 11/21/2012 Physician Gb
Primary
Concomitant
Wheezing Other Serious 11/5/2012 71 Male 154 lb 11/28/2012 Physician Gb
Primary
Concomitant
Weight Decreased Other Serious Female 140 lb 2/8/2013 Physician Us
Primary
Concomitant
Hyponatraemia Other Serious 58 Male 12/28/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Device Related Infection Hospitalization 12/10/2012 82 Female 155 lb 2/12/2013 Physician Us
Primary
Concomitant
Vomiting Hospitalization 12/7/2012 63 Male 1/4/2013 Pharmacist Gb
Primary
Secondary
Concomitant
Subileus Hospitalization 12/3/2012 54 Male 207 lb 3/6/2013 Physician De
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/7/2012 63 Male 1/2/2013 Pharmacist Gb
Primary
Secondary
Concomitant
Feeling Abnormal Other Serious 12/1/2012 59 Female 267 lb 1/7/2013 Physician Gb
Primary
Concomitant
Cholecystitis Acute Hospitalization 12/10/2012 63 Female 211 lb 5/3/2013 Physician Us
Primary
Concomitant
Deep Vein Thrombosis Life Threatening 1/10/2013 83 Male 143 lb 2/6/2013 Pharmacist Gb
Primary
Concomitant
Thrombocytopenia Other Serious 12/2012 29 Female 241 lb 4/10/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Weight Increased Other Serious Female 177 lb 2/21/2013 Consumer Country Not Specified
Primary
Concomitant
Spinal Disorder Other Serious 7/23/2012 66 Male 159 lb 4/30/2013 Consumer Country Not Specified
Primary
Concomitant
Autoimmune Haemolytic Anaemia Hospitalization 1/18/2013 56 Male 5/2/2013 Other Health Professional Fr
Primary
Secondary
Concomitant
Hepatocellular Injury Hospitalization 1/18/2013 56 Male 7/23/2013 Physician Fr
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 12/7/2012 79 Male 2/15/2013 Other Health Professional Dk
Primary
Secondary
Concomitant
Wound Haematoma Disability 2/15/2013 78 Male 181 lb 3/11/2013 Consumer Gb
Primary
Secondary
Wound Haematoma Disability 2/15/2013 78 Male 181 lb 3/14/2013 Physician Gb
Primary
Secondary
Vision Blurred Other Serious 3/6/2013 88 Female 170 lb 3/25/2013 Other Health Professional Gb
Primary
Concomitant
Vision Blurred Other Serious 3/6/2013 88 Female 170 lb 3/26/2013 Other Health Professional Gb
Primary
Concomitant
Hyponatraemia Other Serious 2/18/2013 84 Female 3/17/2013 Gb
Primary
Concomitant
Vision Blurred Other Serious 3/6/2013 88 Female 170 lb 3/26/2013 Other Health Professional Gb
Primary
Concomitant
White Blood Cell Count Increased Other Serious 3/12/2013 40 Female 154 lb 4/29/2013 Other Health Professional Ie
Primary
Concomitant
Pain Hospitalization 4/14/2010 27 Female 12/30/2013 Consumer Us
Primary
Concomitant
Vision Blurred Other Serious 3/6/2013 88 Female 4/2/2013 Other Health Professional Gb
Primary
Concomitant
Ulcer Haemorrhage Hospitalization 4/6/2011 80 Female 129 lb 10/4/2013 Consumer Us
Primary
Concomitant
Pyrexia Hospitalization 3/10/2013 81 Male 177 lb 10/8/2013 Physician Gb
Primary
Secondary
Concomitant
Sleep Disorder Other Serious 7/26/2012 54 Female 198 lb 4/29/2013 Physician Gb
Primary
Concomitant
Pyoderma Gangrenosum Other Serious 2/18/2013 78 Male 187 lb 8/8/2013 Physician De
Primary
Concomitant
Pulmonary Oedema Death 5/27/2013 62 Female 159 lb 12/5/2013 Registered Nurse Gb
Primary
Concomitant
Foot Fracture Other Serious 6/3/2013 68 Male 192 lb 7/24/2013 Physician Se
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Hospitalization 3/6/2012 82 Female 12/12/2013 Consumer Country Not Specified
Primary
Concomitant
Vitiligo Other Serious 2001 49 Female 9/23/2013 Other Health Professional Us
Primary
Concomitant
Rash Other Serious 8/2012 50 Female 7/2/2013 Pharmacist Ie
Primary
Concomitant
Abdominal Sepsis Hospitalization 5/24/2013 45 Female 7/8/2013 Physician Gb
Primary
Concomitant
Tunnel Vision Other Serious 42 Female 273 lb 7/15/2013 Physician Gb
Primary
Concomitant
Pancytopenia Life Threatening 4/14/2013 88 Female 157 lb 7/15/2013 Physician Gb
Primary
Concomitant
Pancytopenia Hospitalization 4/14/2013 88 Female 157 lb 7/16/2013 Physician Gb
Primary
Concomitant
Rectal Haemorrhage Other Serious 7/6/2013 27 Female 9/9/2013 Other Health Professional Gb
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Disability 6/18/2013 91 Female 126 lb 7/19/2013 Other Health Professional Gb
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Disability 6/18/2013 91 Female 126 lb 7/29/2013 Physician Gb
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Disability 6/18/2013 91 Female 126 lb 7/29/2013 Physician Gb
Primary
Concomitant
Hyperuricaemia Other Serious 7/30/2013 71 Female 211 lb 8/23/2013 Physician Us
Primary
Secondary
Concomitant
Varices Oesophageal Death 6/1/2013 60 Male 8/7/2013 Physician Us
Primary
Concomitant
Heart Rate Increased Other Serious 9/6/2013 58 Male 9/11/2013 Consumer Us
Primary
Concomitant
Rash Life Threatening 4/15/2013 62 Female 110 lb 9/13/2013 Physician Country Not Specified
Primary
Concomitant
Haemorrhage Intracranial Death 6/6/2013 33 Female 180 lb 10/3/2013 Physician Us
Primary
Secondary
Concomitant
Petechiae 2013 56 Female 9/24/2013 Consumer Us
Primary
Concomitant
Somnolence Hospitalization 11/14/2008 37 Female 139 lb 9/30/2013 Pharmacist Pt
Primary
Concomitant
Interacting
Pulmonary Embolism Life Threatening 8/9/2013 70 Male 238 lb 10/7/2013 Consumer Gb
Primary
Concomitant
Left Ventricular Dysfunction Death 9/18/2013 67 Male 177 lb 10/9/2013 Physician Us
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 10/2/2013 78 Male 10/28/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 10/2/2013 78 Male 10/28/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Pulmonary Congestion Death Male 10/29/2013 Physician Ph
Primary
Concomitant
Renal Failure Acute Hospitalization 10/2/2013 78 Male 10/30/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Neutropenic Sepsis Death 10/23/2013 75 Female 110 lb 11/26/2013 Physician Us
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 10/2/2013 78 Male 10/28/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 10/2/2013 78 Male 11/1/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 10/2/2013 78 Male 10/30/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 10/2/2013 78 Male 11/5/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 10/2/2013 78 Male 11/6/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 10/2/2013 78 Male 11/6/2013 Consumer Gb
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Hospitalization 10/10/2013 26 Female 134 lb 11/6/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Spinal Pain Hospitalization 2013 69 Female 12/5/2013 Consumer Us
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 10/10/2013 26 Female 134 lb 11/11/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 10/10/2013 26 Female 134 lb 11/12/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Hospitalization 10/10/2013 26 Female 134 lb 11/15/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Hospitalization 10/10/2013 26 Female 134 lb 11/15/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Portal Hypertension Hospitalization 10/2005 57 Female 135 lb 8/16/2013 Pharmacist Us
Primary
Concomitant
Visual Acuity Reduced Other Serious 5/1994 60 Male 8/12/2013 Consumer Us
Primary
Secondary
Concomitant
Peripheral Arterial Occlusive Disease Hospitalization 3/17/2012 72 Male 207 lb 1/29/2013 Physician Gb
Primary
Concomitant
Vomiting Other Serious 3/16/2012 87 Female 196 lb 7/22/2013 Physician Us
Primary
Secondary
Concomitant

Drug Data