Lactulose combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Oral Intake Reduced Other Serious 10/8/2003 Male 1/3/2006 United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Disease Life Threatening 11/23/2005 63 Female 121 lb 1/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hepatic Failure Death 9/1/2005 Male 1/27/2006 United Kingdom
Primary
Secondary
Concomitant
Mesothelioma Death 77 Male 1/24/2006 Other Health Professional United Kingdom
Primary
Secondary
Small Cell Lung Cancer Stage Unspecified Death 5/1/2004 77 Male 1/31/2006 Physician United Kingdom
Primary
Secondary
Mesothelioma Death 77 Male 2/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Death 1/18/2006 85 Male 2/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Death 1/18/2006 85 Male 3/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Neutropenia Life Threatening 2/3/2006 53 Male 159 lb 2/13/2006 Consumer Colombia
Primary
Secondary
Concomitant
Neutropenia Life Threatening 2/3/2006 53 Male 159 lb 2/17/2006 Consumer Colombia
Primary
Secondary
Concomitant
Renal Failure Death 1/18/2006 85 Male 3/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Neutropenia Life Threatening 2/3/2006 53 Male 159 lb 2/24/2006 Consumer Colombia
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 3/10/2006 Female 110 lb 3/15/2006 Pharmacist United States
Primary
Concomitant
Pleural Effusion Hospitalization 2/25/2006 75 Male 160 lb 3/10/2006 Canada
Primary
Concomitant
Pleural Effusion Hospitalization 2/25/2006 75 Male 160 lb 4/10/2006 Physician Canada
Primary
Concomitant
Ammonia Increased Hospitalization 2/14/2006 Male 211 lb 4/6/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 6/22/2005 45 Female 150 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Platelet Count Decreased Other Serious 1/23/2006 95 Female 5/8/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 1/23/2006 95 Female 5/18/2006 United Kingdom
Primary
Secondary
Concomitant
Transfusion Reaction Hospitalization 3/10/2006 51 Female 160 lb 5/12/2006 Physician United States
Primary
Concomitant
Transfusion Reaction Hospitalization 3/10/2006 51 Female 160 lb 5/30/2006 Physician United States
Primary
Concomitant
Hypoglycaemia Hospitalization 5/1/2006 70 Female 130 lb 6/15/2006 Consumer United States
Primary
Concomitant
Mesothelioma Other Serious 5/1/2004 Male 6/22/2006 Consumer United Kingdom
Primary
Secondary
Mesothelioma Death 5/1/2004 Male 6/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Transfusion Reaction Hospitalization 3/10/2006 51 Female 160 lb 6/19/2006 Physician United States
Primary
Concomitant
Lung Neoplasm Malignant Death 5/1/2004 Male 6/22/2006 United Kingdom
Primary
Secondary
Mesothelioma Other Serious 5/1/2004 77 Male 7/5/2006
Primary
Secondary
Mesothelioma Death 5/1/2004 Male 6/27/2006 United Kingdom
Primary
Secondary
Mesothelioma Death 5/1/2004 Male 6/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 7/21/1999 62 Female 128 lb 7/10/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Mesothelioma Death 5/1/2004 Male 6/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 2/25/2006 75 Male 160 lb 6/29/2006 Physician Canada
Primary
Concomitant
Skin Exfoliation Hospitalization 6/19/2006 62 Male 7/7/2006 Pharmacist United States
Primary
Concomitant
Mesothelioma Death 5/1/2004 77 Male 7/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Mesothelioma Death 5/1/2004 Male 7/11/2006 United Kingdom
Primary
Secondary
Concomitant
Mesothelioma Death 5/1/2004 77 Male 7/11/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Mesothelioma Death 5/1/2004 Male 7/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Grand Mal Convulsion 5/29/2006 41 7/18/2006 United Kingdom
Primary
Concomitant
Pleural Effusion Hospitalization 2/25/2006 75 Male 160 lb 7/19/2006 Physician Canada
Primary
Concomitant
Respiratory Failure Hospitalization 10/31/2005 45 Female 7/28/2006 Physician Germany
Primary
Secondary
Concomitant
Mesothelioma Death 5/1/2004 77 Male 7/25/2006 United Kingdom
Primary
Secondary
Concomitant
Transfusion Reaction Hospitalization 3/10/2006 51 Female 160 lb 7/27/2006 Physician United States
Primary
Concomitant
Urinary Incontinence 3/10/2006 Female 110 lb 7/12/2006 United States
Primary
Concomitant
Pancytopenia Hospitalization 1/10/2006 90 Male 8/11/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Hepatic Encephalopathy Hospitalization 3/7/2005 55 Male 8/21/2006 Other Health Professional Argentina
Primary
Secondary
Concomitant
Hypoaesthesia Female 8/28/2006 Consumer United States
Primary
Concomitant
Haemoptysis 71 Female 136 lb 7/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Sick Sinus Syndrome Hospitalization 6/25/2006 69 Female 139 lb 8/21/2006 Pharmacist United States
Primary
Secondary
Concomitant
Renal Pain 9/27/2006 Consumer United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 5/11/2006 79 Female 154 lb 10/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 79 Female 154 lb 9/29/2006 United Kingdom
Primary
Concomitant
Vaginal Candidiasis Hospitalization 3/25/2006 64 Female 10/9/2006 Consumer Australia
Primary
Concomitant
Respiratory Tract Infection Hospitalization 9/22/2005 65 183 lb 10/11/2006 Physician Ireland
Primary
Concomitant
Tendonitis Other Serious 10/1/2004 68 Male 10/12/2006 Physician Sweden
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 9/16/2005 65 183 lb 10/19/2006 Physician Ireland
Primary
Concomitant
Escherichia Infection Hospitalization 6/7/2006 Female 10/19/2006 Physician
Primary
Concomitant
Myalgia Required Intervention 7/27/2006 47 Male 265 lb 9/20/2006 Pharmacist United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 9/16/2006 Female 10/26/2006 Physician United States
Primary
Concomitant
Encephalopathy Hospitalization 87 Male 10/23/2006 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious Female 161 lb 11/3/2006 Pharmacist United States
Primary
Concomitant
Melaena Life Threatening 8/14/2006 31 Female 11/2/2006 United Kingdom
Primary
Secondary
Concomitant
Melaena Other Serious 8/14/2006 31 Female 11/9/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachycardia Hospitalization 5/2/2003 55 Male 238 lb 11/6/2006 Physician United States
Primary
Secondary
Concomitant
Melaena Other Serious 8/14/2006 31 Female 137 lb 11/8/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Melaena Life Threatening 8/14/2006 31 Female 137 lb 11/9/2006 United Kingdom
Primary
Secondary
Concomitant
Melaena Other Serious 8/14/2006 31 Female 137 lb 11/9/2006 United Kingdom
Primary
Secondary
Concomitant
Melaena Other Serious 8/14/2006 31 Female 137 lb 11/14/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Melaena Other Serious 8/14/2006 31 Female 11/17/2006 Lawyer United Kingdom
Primary
Secondary
Concomitant
Milk-alkali Syndrome Hospitalization 50 Female 11/29/2006
Primary
Secondary
Concomitant
Melaena Life Threatening 8/14/2006 31 Female 137 lb 11/17/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urethral Haemorrhage Other Serious 10/30/2006 Male 181 lb 12/4/2006 Physician Czech Republic
Primary
Concomitant
Thrombocytopenia Other Serious 10/24/2006 Female 161 lb 12/4/2006 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Other Serious 10/24/2006 Female 161 lb 12/5/2006 Pharmacist United States
Primary
Concomitant
Pain Other Serious 8/14/2006 31 Female 137 lb 11/27/2006 United Kingdom
Primary
Secondary
Concomitant
Melaena Other Serious 8/14/2006 31 Female 137 lb 11/27/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypothyroidism Hospitalization 7/5/2006 52 Female 149 lb 11/28/2006 Physician Germany
Primary
Concomitant
Melaena Other Serious 8/14/2006 31 Female 11/28/2006 United Kingdom
Primary
Secondary
Concomitant
Melaena Other Serious 8/14/2006 31 Female 11/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Melaena Other Serious 8/14/2006 31 Female 137 lb 11/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 50 Female 12/28/2006
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 12/4/2005 87 Male 168 lb 12/19/2006 United Kingdom
Primary
Concomitant
Paraesthesia Oral 71 Female 136 lb 10/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Sputum Discoloured Hospitalization 12/4/2006 Male 160 lb 1/12/2007 Canada
Primary
Concomitant
Hyperthyroidism Hospitalization 2/17/2006 72 Male 183 lb 1/15/2007 Physician France
Primary
Concomitant
Hyponatraemia Other Serious 93 Female 1/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Oesophageal Varices Haemorrhage Death 1/23/2007 71 Male 115 lb 2/13/2007 Physician Japan
Primary
Secondary
Concomitant
Syncope Hospitalization 12/14/2006 80 Male 2/15/2007 Pharmacist United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 10/27/2006 64 Male 2/16/2007 Pharmacist United States
Primary
Secondary
Concomitant
Proteinuria Disability 1/9/2007 52 Female 262 lb 3/5/2007 Other Health Professional United Kingdom
Primary
Concomitant
Oesophageal Varices Haemorrhage Death 1/23/2007 71 Male 115 lb 3/6/2007 Physician Japan
Primary
Secondary
Concomitant
Mesothelioma Death 5/1/2004 77 Male 3/1/2007 United Kingdom
Primary
Secondary
Mesothelioma Death 5/1/2004 Male 3/8/2007 Other Health Professional United Kingdom
Primary
Secondary
Tremor Other Serious 1/1/2007 51 Male 3/8/2007 Physician United States
Primary
Secondary
Concomitant
Mesothelioma Death 5/1/2004 77 Male 3/15/2007 Other Health Professional United Kingdom
Primary
Secondary
Melaena Other Serious 8/14/2006 31 Female 137 lb 3/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Mesothelioma Death 5/1/2004 77 Male 3/9/2007 United Kingdom
Primary
Secondary
Concomitant
Melaena Hospitalization 12/15/2005 63 Male 3/21/2007 United Kingdom
Primary
Concomitant
Mesothelioma Death 5/1/2004 77 Male 3/15/2007 United Kingdom
Primary
Secondary
Mesothelioma Death 5/1/2004 77 Male 3/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Melaena Hospitalization 12/15/2005 63 Male 3/27/2007 United Kingdom
Primary
Concomitant
Melaena Life Threatening 8/14/2006 31 Female 3/20/2007 United Kingdom
Primary
Secondary
Concomitant
Mesothelioma Death 5/1/2004 77 Male 3/22/2007 United Kingdom
Primary
Secondary
Melaena Other Serious 8/14/2006 31 Female 137 lb 3/28/2007 United Kingdom
Primary
Secondary
Concomitant
Vision Blurred Required Intervention 12/18/2006 66 Male 12/29/2006 Pharmacist United States
Primary
Secondary
Concomitant
Blood Creatine Increased Required Intervention 4/24/2006 39 Male 237 lb 1/3/2007 United States
Primary
Concomitant
Mesothelioma Death 5/1/2004 77 Male 3/29/2007 United Kingdom
Primary
Secondary
Mesothelioma Death 5/1/2004 77 Male 4/4/2007 United Kingdom
Primary
Secondary
Mesothelioma Death 5/1/2004 77 Male 4/12/2007 Consumer United Kingdom
Primary
Secondary
Encephalopathy Hospitalization 2/22/2007 69 Male 4/16/2007 Other Health Professional France
Primary
Concomitant
Mesothelioma Other Serious 5/1/2004 77 Male 4/20/2007
Primary
Secondary
Melaena Other Serious 8/14/2006 31 Female 137 lb 4/25/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Constipation Hospitalization 5/16/2006 Female 93 lb 5/1/2007 Japan
Primary
Concomitant
Tremor Other Serious 1/1/2007 51 Male 4/27/2007 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 1/24/2007 73 Male 201 lb 2/12/2007 Pharmacist United States
Primary
Concomitant
Pallor Hospitalization 5/11/2006 79 Female 154 lb 5/18/2007 Other Health Professional United Kingdom
Primary
Concomitant
Headache 12/4/2006 47 Male 254 lb 5/25/2007 Consumer United States
Primary
Concomitant
Mesothelioma Death 5/1/2004 77 Male 5/25/2007 United Kingdom
Primary
Secondary
Pulmonary Embolism Other Serious 4/8/2007 51 Female 183 lb 5/30/2007 Consumer United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 5/1/2007 50 Female 220 lb 6/21/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vitamin D Deficiency Other Serious 1/1/2004 Male 159 lb 6/22/2007 Other Health Professional United States
Primary
Concomitant
Constipation Hospitalization 5/8/2006 Female 93 lb 6/26/2007 Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 5/1/2007 50 Female 7/6/2007 United Kingdom
Primary
Concomitant
Postoperative Wound Infection Hospitalization 2/5/2004 75 Female 176 lb 8/1/2007 Other Health Professional Germany
Primary
Concomitant
Insomnia 3/1/2007 55 Female 100 lb 7/10/2007 Consumer United States
Primary
Concomitant
Vitamin D Deficiency Other Serious 1/1/2004 Male 159 lb 8/22/2007 Other Health Professional United States
Primary
Concomitant
Vitamin D Deficiency Other Serious 1/1/2004 Male 159 lb 8/31/2007 Other Health Professional United States
Primary
Concomitant
Hypotension Hospitalization 7/6/2007 50 Male 9/4/2007 Other Health Professional Philippines
Primary
Secondary
Concomitant
Seroma Hospitalization 1/9/2006 Female 150 lb 9/5/2007 Physician Switzerland
Primary
Concomitant
Seroma Hospitalization 4/20/2006 Female 152 lb 9/6/2007 Physician Switzerland
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 10/27/2005 Male 9/7/2007 United Kingdom
Primary
Secondary
Concomitant
Wound Infection Bacterial Hospitalization 2/5/2004 75 Female 176 lb 9/10/2007 Consumer Germany
Primary
Concomitant
Wound Infection Bacterial Hospitalization 2/5/2004 75 Female 176 lb 9/18/2007 Consumer Germany
Primary
Concomitant
Spinal Column Stenosis Hospitalization 2/5/2004 75 Female 176 lb 9/20/2007 Germany
Primary
Concomitant
Neck Pain 6/21/2007 37 Female 300 lb 9/20/2007 Consumer United States
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 10/27/2005 Male 10/1/2007 United Kingdom
Primary
Secondary
Concomitant
Tremor Other Serious 12/1/2006 51 Male 7/9/2007 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/11/2007 74 Female 10/11/2007 Consumer Japan
Primary
Concomitant
Wound Infection Bacterial Hospitalization 2/5/2004 75 Female 176 lb 10/10/2007 Consumer Germany
Primary
Concomitant
Vomiting Hospitalization 9/11/2007 74 Female 10/19/2007 Consumer Japan
Primary
Concomitant
Vomiting Hospitalization 12/21/2005 81 Female 10/25/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Rash Pruritic Other Serious 10/18/2007 Male 181 lb 10/22/2007 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 12/21/2005 81 Female 10/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Skin Cancer Other Serious 10/1/2007 81 Male 10/29/2007 Consumer France
Primary
Concomitant
Vomiting Hospitalization 12/21/2005 10/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Skin Cancer Other Serious 10/1/2007 81 Male 10/31/2007 Physician France
Primary
Concomitant
Platelet Count Decreased Hospitalization 4/6/2006 Female 93 lb 10/31/2007 Japan
Primary
Concomitant
Vomiting Hospitalization 12/21/2005 81 Female 10/25/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombophlebitis Hospitalization 4/6/2006 Female 93 lb 11/5/2007 Japan
Primary
Concomitant
Proteinuria Death 1/9/2007 Female 235 lb 11/7/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2005 Male 242 lb 11/9/2007 Consumer United States
Primary
Concomitant

Drug Data