Lactulose combined with Senna

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Respiratory Arrest Death 12/7/2003 56 Male 1/12/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Death 10/7/2004 50 9/12/2005 Physician United States
Primary
Concomitant
Constipation Hospitalization 9/5/2005 67 Female 1/17/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Rales Life Threatening 11/11/2005 85 Female 1/23/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/8/2006 36 Female 159 lb 2/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Other Serious 12/29/2001 79 Male 10/11/2005 Physician United States
Primary
Secondary
Concomitant
Osteoporosis Hospitalization 2/15/2004 Female 112 lb 2/9/2006 United Kingdom
Primary
Concomitant
Paraesthesia Hospitalization 12/4/2005 21 Male 159 lb 2/17/2006 United Kingdom
Primary
Concomitant
Renal Failure Death 1/18/2006 85 Male 2/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Death 1/18/2006 85 Male 3/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Death 1/18/2006 85 Male 3/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Other Serious 9/1/2001 70 Female 126 lb 4/14/2006 Physician Canada
Primary
Concomitant
General Physical Health Deterioration Life Threatening 4/19/2006 Female 153 lb 5/2/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/23/2006 74 Female 5/5/2006 Other Health Professional France
Primary
Secondary
Concomitant
Loss Of Consciousness Required Intervention 12/13/2005 53 Male 169 lb 3/1/2006 United States
Primary
Concomitant
Rash Macular Hospitalization 1/1/2005 65 Female 4/28/2006 Pharmacist Singapore
Primary
Concomitant
Tachycardia Hospitalization 4/13/2006 60 Male 157 lb 5/12/2006 Consumer United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Life Threatening 4/19/2006 Female 153 lb 5/22/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Osteoporosis Hospitalization 2/15/2004 Female 112 lb 5/23/2006 Consumer United Kingdom
Primary
Concomitant
General Physical Health Deterioration Life Threatening 4/19/2006 Female 153 lb 5/24/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Ulcer Haemorrhage Other Serious 2/28/2005 62 Female 179 lb 5/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Purulence Life Threatening 4/24/2006 52 Male 164 lb 6/6/2006 United Kingdom
Primary
Concomitant
Non-hodgkin's Lymphoma Death 78 Female 6/26/2006 Other Health Professional United Kingdom
Primary
Secondary
Non-hodgkin's Lymphoma Death 78 Female 6/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Hypomagnesaemia Life Threatening 6/9/2006 62 Female 7/6/2006 Pharmacist United Kingdom
Primary
Concomitant
Non-hodgkin's Lymphoma Death 80 Female 6/28/2006 United Kingdom
Primary
Secondary
Non-hodgkin's Lymphoma Death 78 Female 6/27/2006 Other Health Professional United Kingdom
Primary
Secondary
Non-hodgkin's Lymphoma Death 78 Female 6/23/2006 Other Health Professional United Kingdom
Primary
Secondary
Non-hodgkin's Lymphoma Death 78 Female 7/6/2006 United Kingdom
Primary
Secondary
Myoclonus Hospitalization 4/23/2006 Male 7/18/2006 Pharmacist United States
Primary
Concomitant
Cerebrovascular Disorder Death 9/17/2003 Male 368 lb 8/2/2006 United Kingdom
Primary
Concomitant
Therapeutic Response Decreased 1/1/2006 Female 8/9/2006 Other Health Professional United States
Primary
Concomitant
Fall Hospitalization Male 8/21/2006 Pharmacist United Kingdom
Primary
Concomitant
Grand Mal Convulsion Disability 2/1/2005 52 Female 8/29/2006
Primary
Concomitant
Rash Macular Hospitalization 6/23/2006 Male 9/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Blood Potassium Decreased Life Threatening 6/9/2006 Female 9/1/2006 Consumer United Kingdom
Primary
Concomitant
Hypoglycaemia Other Serious 1/16/2006 23 Female 196 lb 9/12/2006 Consumer United Kingdom
Primary
Concomitant
Gamma-glutamyltransferase Increased 8/23/2006 48 Female 132 lb 10/13/2006 Pharmacist United Kingdom
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 7/26/2006 90 Male 10/10/2006 Other Health Professional Denmark
Primary
Concomitant
Pneumonia Aspiration Death 9/19/2006 90 Male 10/11/2006 United States
Primary
Concomitant
Self Mutilation Other Serious 28 Female 10/19/2006 Consumer United Kingdom
Primary
Concomitant
Haematemesis Hospitalization 9/6/2006 87 Female 10/18/2006 United Kingdom
Primary
Concomitant
Tremor Hospitalization 8/28/2006 Male 10/23/2006 Pharmacist United States
Primary
Concomitant
Leukopenia Hospitalization 8/22/2006 Male 10/23/2006 Pharmacist United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 9/6/2006 87 Female 10/20/2006 Other Health Professional United Kingdom
Primary
Concomitant
Platelet Count Decreased Hospitalization 6/8/2006 81 Female 11/7/2006 Consumer United Kingdom
Primary
Concomitant
Vomiting Hospitalization 10/28/2006 Female 113 lb 11/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tibia Fracture Other Serious 4/1/2006 52 Male 11/20/2006 Consumer United Kingdom
Primary
Concomitant
Psychotic Disorder Disability 9/1/2006 87 Female 11/8/2006 Physician United Kingdom
Primary
Concomitant
Similar Reaction On Previous Exposure To Drug Hospitalization 9/6/2006 87 Female 11/14/2006 Other Health Professional United Kingdom
Primary
Concomitant
Neutropenic Sepsis Hospitalization 10/8/2006 79 Female 11/17/2006 United Kingdom
Primary
Concomitant
Intestinal Infarction Death 2/9/2006 Male 170 lb 11/29/2006 Physician
Primary
Concomitant
Vomiting Other Serious 10/21/2006 85 Female 12/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Grand Mal Convulsion Other Serious 67 Female 172 lb 12/8/2006 Pharmacist Canada
Primary
Concomitant
Pulmonary Embolism Hospitalization 49 Male 12/14/2006 Other Health Professional United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 12/4/2005 87 Male 168 lb 12/19/2006 United Kingdom
Primary
Concomitant
Neutrophil Count Decreased Life Threatening 12/7/2006 Male 12/28/2006 Pharmacist United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 49 Male 1/4/2007 United Kingdom
Primary
Concomitant
Pneumonia Required Intervention 7/23/2006 68 Female 148 lb 7/28/2006 Pharmacist United States
Primary
Secondary
Concomitant
Peritonitis Life Threatening 4/24/2006 52 Male 163 lb 1/15/2007 United Kingdom
Primary
Concomitant
Pharyngolaryngeal Pain Hospitalization 12/25/2006 78 Male 1/15/2007 Physician
Primary
Concomitant
Pharyngolaryngeal Pain Hospitalization 12/25/2006 78 Male 1/16/2007 Physician
Primary
Concomitant
Ileus Hospitalization 12/22/2006 Male 179 lb 1/11/2007 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 12/1/2006 28 Female 1/17/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 12/1/2006 28 Female 1/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Peritonitis Hospitalization 12/27/2006 58 Female 1/19/2007 United Kingdom
Primary
Concomitant
Haematemesis Hospitalization 9/6/2006 87 Female 1/15/2007 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Death 12/1/2006 28 Female 1/16/2007 United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 11/28/2006 28 Female 1/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Peritonitis Hospitalization 12/27/2006 58 Female 2/5/2007 United Kingdom
Primary
Concomitant
Ankle Fracture Hospitalization 8/17/2004 Female 112 lb 2/6/2007 Other Health Professional United Kingdom
Primary
Concomitant
Intestinal Infarction Hospitalization 1/31/2006 Male 170 lb 2/7/2007 Physician
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2007 47 Female 137 lb 2/19/2007 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 12/1/2006 28 Female 2/22/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 12/1/2006 28 Female 351 lb 2/23/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 11/28/2006 28 Female 351 lb 3/1/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 62 Female 3/19/2007
Primary
Secondary
Urticaria Other Serious 3/19/2007 64 Female 4/4/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Crohn's Disease Other Serious 2/25/2006 Female 130 lb 4/10/2007 Consumer United Kingdom
Primary
Concomitant
Haemorrhage Hospitalization 3/27/2006 Female 130 lb 4/11/2007 Consumer United Kingdom
Primary
Concomitant
Pneumonia Other Serious 1/6/2003 Female 143 lb 4/16/2007 Physician United Kingdom
Primary
Concomitant
Interacting
Speech Disorder Other Serious 3/15/2007 39 Female 132 lb 4/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/13/2006 59 Male 4/20/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Peritonitis Life Threatening 4/24/2006 52 Male 163 lb 4/25/2007 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 9/1/2006 75 Male 163 lb 4/27/2007 Netherlands
Primary
Concomitant
Mixed Connective Tissue Disease Other Serious 6/15/2006 Female 130 lb 4/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vertigo Other Serious 12/1/2006 82 Female 5/1/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Other Serious 1/6/2003 Female 143 lb 5/4/2007 Physician United Kingdom
Primary
Concomitant
Interacting
Vomiting Hospitalization 4/18/2007 Male 176 lb 4/27/2007 Other Health Professional United States
Primary
Concomitant
Peritonitis Sclerosing Hospitalization 3/13/2006 59 Male 5/4/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/25/2006 Male 179 lb 5/4/2007 United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 2/11/2007 Female 112 lb 5/10/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vertigo Other Serious 12/1/2006 82 Female 5/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 62 Female 5/7/2007 United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 2/11/2007 Female 112 lb 5/18/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hypertension Hospitalization 2/15/2006 Male 178 lb 5/21/2007 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/1/2006 75 Male 163 lb 5/29/2007 Netherlands
Primary
Concomitant
Red Blood Cell Abnormality Hospitalization 36 Male 192 lb 6/7/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Disorder Other Serious 1/1/2006 72 Female 229 lb 6/28/2007 Consumer United Kingdom
Primary
Concomitant
Vomiting Hospitalization 1/1/2007 Male 7/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Deep Vein Thrombosis Other Serious 6/27/2007 75 Male 165 lb 7/9/2007 United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 1/6/2003 Female 143 lb 7/17/2007 Physician United Kingdom
Primary
Concomitant
Interacting
Vertigo Other Serious 12/1/2006 82 Female 7/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
Deep Vein Thrombosis Other Serious 6/27/2007 75 Male 165 lb 7/16/2007 Consumer United States
Primary
Secondary
Concomitant
Ototoxicity Disability 1/1/2007 69 Male 110 lb 7/25/2007 United Kingdom
Primary
Concomitant
Visual Disturbance Other Serious 6/27/2007 69 Male 8/1/2007 Pharmacist United Kingdom
Primary
Concomitant
Hyperkalaemia Hospitalization 3/21/2006 76 Male 150 lb 8/16/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Interacting
White Blood Cells Urine Hospitalization 4/12/2007 46 Male 313 lb 4/20/2007 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Required Intervention 3/12/2007 58 Male 225 lb 3/22/2007 Pharmacist United States
Primary
Secondary
Concomitant
Sensory Disturbance Hospitalization 4/12/2007 53 Female 9/13/2007 Pharmacist
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/7/2006 6 Female 34 lb 9/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Fracture Other Serious 94 Female 9/28/2007 Physician United Kingdom
Primary
Concomitant
Dyspnoea Other Serious 10/15/2007 48 Male 121 lb 10/18/2007 Physician Singapore
Primary
Secondary
Concomitant
Vomiting Other Serious 10/15/2007 48 Male 121 lb 10/22/2007 Physician Singapore
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/21/2005 81 Female 10/25/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/21/2005 81 Female 10/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/21/2005 10/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/21/2005 81 Female 10/25/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 10/26/2007 Male 169 lb 11/21/2007 United States
Primary
Secondary
Concomitant
Extradural Haematoma Life Threatening 10/24/2007 42 Male 11/16/2007 Pharmacist United States
Primary
Concomitant
Sepsis Hospitalization 10/26/2007 Male 169 lb 11/27/2007 United States
Primary
Secondary
Concomitant
Mixed Connective Tissue Disease Other Serious 6/15/2006 Female 130 lb 12/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
General Physical Health Deterioration Life Threatening 4/19/2006 Female 153 lb 12/10/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/27/2006 89 Male 12/3/2007 Pharmacist United Kingdom
Primary
Concomitant
Vomiting Hospitalization 5/27/2006 89 Male 12/6/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/27/2006 89 Male 12/6/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 10/26/2007 Male 162 lb 12/17/2007 United States
Primary
Secondary
Concomitant
Encephalopathy Hospitalization 2/15/2006 48 Male 178 lb 12/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/1/2006 75 Male 163 lb 1/29/2008 Netherlands
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 1/25/2008 Female 1/31/2008 Physician United States
Primary
Secondary
Concomitant
Urethritis Hospitalization 1/30/2008 63 Male 2/4/2008 Norway
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 1/25/2008 Female 2/8/2008 Physician United States
Primary
Secondary
Concomitant
Intentional Self-injury Other Serious 28 Female 1/31/2008 United Kingdom
Primary
Concomitant
Haemoglobin Decreased Other Serious 10/30/2007 Male 2/14/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 1/25/2008 Female 2/14/2008 Physician United States
Primary
Secondary
Concomitant
Epistaxis Life Threatening 1/1/2007 76 Male 186 lb 2/20/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 1/25/2008 Female 2/29/2008 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 1/19/2008 83 Male 2/18/2008 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization Male 3/5/2008 Other Health Professional United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 1/25/2008 Female 3/13/2008 Physician United States
Primary
Secondary
Concomitant
Leukocytoclastic Vasculitis Hospitalization 8/4/2007 61 Male 145 lb 3/18/2008 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/26/2008 80 Male 136 lb 3/19/2008 Physician United States
Primary
Concomitant
Pain Life Threatening 3/2/2008 42 Female 4/7/2008
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 3/1/2008 50 Male 163 lb 4/10/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
General Physical Health Deterioration Life Threatening 4/19/2006 Female 153 lb 4/9/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Life Threatening 3/2/2008 42 Female 4/11/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/15/2005 26 Female 124 lb 5/16/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 12/15/2005 26 Female 124 lb 5/21/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 10/25/2006 Male 179 lb 5/27/2008 United Kingdom
Primary
Concomitant
Mixed Connective Tissue Disease Other Serious 6/15/2006 Female 130 lb 5/30/2008 Other Health Professional United Kingdom
Primary
Concomitant

Drug Data