Lactulose combined with Oxycontin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Failure Other Serious 1/1/2004 Male 1/3/2006 Physician Canada
Primary
Concomitant
Upper Respiratory Tract Infection Required Intervention Female 1/5/2006 Physician United States
Primary
Concomitant
Sudden Death Death 12/22/2005 53 Male 1/12/2006 Physician Ireland
Primary
Concomitant
Upper Respiratory Tract Infection Required Intervention Female 1/23/2006 Physician United States
Primary
Concomitant
Rales Life Threatening 11/11/2005 85 Female 1/23/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Required Intervention Female 2/1/2006 Physician United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Required Intervention 55 Female 2/17/2006 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/15/2005 68 Male 2/21/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Haematuria Hospitalization 12/31/2005 41 Male 134 lb 2/13/2006 United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/1/2004 Male 2/28/2006 Physician Canada
Primary
Concomitant
Pain Hospitalization 1/17/2006 37 Male 170 lb 2/7/2006 Other Health Professional United States
Primary
Concomitant
Nephrotic Syndrome Hospitalization 1/17/2006 37 Male 170 lb 2/9/2006 Consumer United States
Primary
Concomitant
Upper Respiratory Tract Infection Required Intervention 55 Female 3/6/2006 Physician United States
Primary
Concomitant
Sensory Loss Hospitalization 8/15/2005 68 Male 3/8/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Haematuria Hospitalization 12/31/2005 41 Male 134 lb 3/8/2006 United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Required Intervention 55 Female 3/14/2006 Physician United States
Primary
Concomitant
Renal Failure Other Serious 7/25/2005 51 Male 262 lb 3/8/2006 United States
Primary
Concomitant
Upper Respiratory Tract Infection Required Intervention 55 Female 3/28/2006 United States
Primary
Concomitant
Wheezing Other Serious 2/23/1997 44 Male 219 lb 4/4/2006 Physician United States
Primary
Concomitant
Oedema Peripheral Hospitalization 8/1/2000 79 Female 176 lb 4/24/2006 Physician United States
Primary
Concomitant
Hypomagnesaemia Life Threatening 6/9/2006 62 Female 7/6/2006 Pharmacist United Kingdom
Primary
Concomitant
Respiratory Failure Death 7/2/2006 59 Male 209 lb 7/11/2006 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 5/1/2005 73 Male 247 lb 8/1/2006 Consumer United States
Primary
Concomitant
Blood Potassium Decreased Life Threatening 6/9/2006 Female 9/1/2006 Consumer United Kingdom
Primary
Concomitant
Chest Discomfort Disability 2/16/2006 43 Female 8/30/2006 Australia
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/29/2006 70 Female 9/18/2006 Physician Sweden
Primary
Concomitant
Small Intestinal Obstruction Other Serious 4/4/2005 76 Male 10/2/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tumour Marker Increased Other Serious 9/1/2000 47 Female 225 lb 10/9/2006 United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 9/18/2006 53 Female 152 lb 10/9/2006 United States
Primary
Concomitant
Neutropenic Sepsis Hospitalization 10/8/2006 79 Female 11/17/2006 United Kingdom
Primary
Concomitant
Neutropenic Sepsis Hospitalization 10/8/2006 79 Female 11/20/2006 United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/8/2006 79 Female 11/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Nausea Other Serious 62 Male 150 lb 12/1/2006 Consumer Netherlands
Primary
Concomitant
Intestinal Obstruction Hospitalization 10/29/2006 52 Female 123 lb 12/22/2006 Physician Australia
Primary
Secondary
Concomitant
Wound Debridement Other Serious 4/20/2004 47 Female 8/29/2006 Physician United States
Primary
Concomitant
Oral Pain 9/1/2006 53 Female 152 lb 10/24/2006 United States
Primary
Concomitant
Intestinal Obstruction Hospitalization 10/29/2006 52 Female 123 lb 1/12/2007 Physician Australia
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 10/29/2006 52 Female 123 lb 1/18/2007 Physician Australia
Primary
Secondary
Concomitant
Viral Infection Hospitalization 11/19/2006 70 Female 2/7/2007 Physician Sweden
Primary
Concomitant
Pulmonary Embolism Other Serious 11/30/2006 73 Male 194 lb 2/6/2007 United Kingdom
Primary
Concomitant
Heart Rate Abnormal Disability 2/16/2006 43 Female 2/17/2007 Australia
Primary
Secondary
Concomitant
Lung Cancer Metastatic Death 11/1/2006 Female 132 lb 3/7/2007 Physician Netherlands
Primary
Concomitant
Thrombocytopenia Hospitalization 2/16/2007 56 Female 236 lb 3/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 39 Male 11/13/2006 Physician United States
Primary
Concomitant
Thrombocytopenia Hospitalization 2/16/2007 56 Female 236 lb 3/27/2007 Physician United States
Primary
Secondary
Concomitant
Speech Disorder Other Serious 3/15/2007 39 Female 132 lb 4/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Wound Hospitalization 12/25/2002 20 Male 4/11/2007 Physician United States
Primary
Secondary
Concomitant
Nephritis Interstitial Hospitalization 9/7/2006 Male 198 lb 5/2/2007 Australia
Primary
Concomitant
Somnolence Disability 43 Female 5/3/2007
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/18/2007 Male 176 lb 4/27/2007 Other Health Professional United States
Primary
Concomitant
Transfusion Required Intervention 8/5/2006 65 Female 91 lb 5/10/2007 Physician United States
Primary
Secondary
Concomitant
Renal Haemorrhage Hospitalization 4/22/2007 Female 168 lb 5/25/2007 Norway
Primary
Concomitant
Renal Haemorrhage Hospitalization 4/22/2007 Female 168 lb 5/29/2007 Norway
Primary
Concomitant
Appendicitis Perforated Other Serious 12/19/2006 46 Female 2/28/2007 Physician United States
Primary
Concomitant
Vomiting Hospitalization 5/9/2007 Male 110 lb 5/18/2007 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 5/12/2007 Male 120 lb 5/18/2007 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 5/18/2007 Male 170 lb 6/1/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 4/22/2007 Female 168 lb 6/12/2007 Norway
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 4/25/2006 47 Female 203 lb 6/13/2007 Physician Australia
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 4/22/2007 Female 168 lb 7/2/2007 Norway
Primary
Concomitant
Pneumonia Hospitalization 3/22/2007 63 106 lb 6/28/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 4/22/2007 Female 168 lb 7/11/2007 Norway
Primary
Concomitant
Vesical Fistula Required Intervention 2/27/2007 81 Female 154 lb 7/23/2007 Physician United States
Primary
Secondary
Concomitant
Vesical Fistula Required Intervention 2/27/2007 81 Female 154 lb 8/16/2007 Physician United States
Primary
Secondary
Concomitant
Oral Intake Reduced Hospitalization 7/3/2007 69 Male 9/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Required Intervention 1/1/2007 77 Female 9/4/2007 Physician United States
Primary
Concomitant
Nephritis Interstitial Hospitalization 9/7/2006 Male 198 lb 9/17/2007 Australia
Primary
Concomitant
Thrombosis Hospitalization 7/16/2007 60 Female 9/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 4/22/2007 Female 168 lb 9/26/2007 Norway
Primary
Concomitant
Speech Disorder Hospitalization 3/27/2006 68 Male 150 lb 9/27/2007
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 3/27/2006 68 Male 150 lb 9/28/2007
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 3/27/2006 68 Male 150 lb 10/1/2007
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 8/1/2007 Male 10/3/2007
Primary
Concomitant
Sepsis Hospitalization 10/26/2007 Male 169 lb 11/21/2007 United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 10/26/2007 Male 169 lb 11/27/2007 United States
Primary
Secondary
Concomitant
Coma Hospitalization 4/1/2003 98 Female 11/28/2007 Netherlands
Primary
Concomitant
Bowel Movement Irregularity Hospitalization 8/29/2007 71 Male 11/30/2007 Physician Sweden
Primary
Secondary
Concomitant
Constipation Hospitalization 8/29/2007 71 Male 12/6/2007 Physician Sweden
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 4/25/2006 47 Female 203 lb 12/13/2007 Physician Australia
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Death 30 Male 146 lb 12/17/2007 Physician Australia
Primary
Concomitant
Sepsis Hospitalization 10/26/2007 Male 162 lb 12/17/2007 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 4/22/2007 Female 168 lb 12/20/2007 Norway
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/28/2004 63 Male 381 lb 1/3/2008 Physician United States
Primary
Concomitant
Dehydration Hospitalization 7/3/2007 69 Male 1/7/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Constipation Hospitalization 8/29/2007 71 Male 1/23/2008 Physician Sweden
Primary
Secondary
Concomitant
Varices Oesophageal Other Serious 1/1/2003 Female 2/6/2008 Consumer United States
Primary
Concomitant
Renal Cell Carcinoma Death 11/23/2007 Male 154 lb 3/18/2008 Physician Australia
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/19/2008 Male 159 lb 3/27/2008 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/19/2008 Male 159 lb 4/2/2008 Consumer United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 11/23/2007 67 Male 246 lb 6/6/2008 Physician Australia
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 4/22/2007 Female 168 lb 6/19/2008 Norway
Primary
Concomitant
Speech Disorder Hospitalization 3/27/2006 68 Male 150 lb 6/30/2008 Physician United States
Primary
Secondary
Concomitant
Cardiac Arrest Life Threatening 6/6/2008 43 Female 139 lb 6/30/2008 Physician United States
Primary
Secondary
Concomitant
Psychotic Disorder Hospitalization 3/27/2006 Male 7/1/2008 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Death 5/16/2008 54 Male 158 lb 7/2/2008 United States
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 3/27/2006 68 Male 150 lb 7/29/2008 Physician United States
Primary
Secondary
Concomitant
Psychotic Disorder Hospitalization 3/27/2006 68 Male 150 lb 7/31/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 5/1/2008 53 Female 8/8/2008 Physician United States
Primary
Concomitant
Gastric Perforation Hospitalization 9/5/2008 Male 115 lb 9/16/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Rectal Cancer Life Threatening Male 9/17/2008 Other Health Professional Netherlands
Primary
Concomitant
Gastric Perforation Hospitalization 9/5/2008 Male 115 lb 9/30/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Dehydration Hospitalization 7/3/2007 69 Male 10/3/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Multiple Myeloma Death 1/1/2007 68 Male 10/16/2007 Physician United States
Primary
Concomitant
Syncope Other Serious 10/15/2008 Female 10/31/2008 Peru
Primary
Concomitant
Neutropenia Hospitalization 10/26/2007 Male 162 lb 11/10/2008 United States
Primary
Secondary
Concomitant
Nausea Hospitalization 7/3/2007 69 Male 11/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Memory Impairment Hospitalization 1/21/2002 57 Male 174 lb 11/24/2008 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 10/6/2008 Male 148 lb 12/1/2008 Japan
Primary
Concomitant
Gastric Perforation Life Threatening 7/19/2008 Male 12/2/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Viral Infection Hospitalization 11/19/2006 70 Female 12/4/2008 Physician Sweden
Primary
Concomitant
Pneumonia Hospitalization 8/29/2006 70 Female 12/4/2008 Physician Sweden
Primary
Concomitant
Pain Other Serious 1/1/2007 Male 110 lb 12/23/2008 Physician United States
Primary
Secondary
Concomitant
Gastric Perforation Life Threatening 7/19/2008 Male 12/30/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 10/6/2008 Male 148 lb 12/31/2008 Physician Japan
Primary
Concomitant
Muscle Twitching Other Serious 11/14/2008 60 Male 2/5/2009 Physician Norway
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/26/2009 25 Female 159 lb 2/5/2009 Pharmacist Canada
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2008 58 Male 154 lb 2/11/2009 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 62 Male 2/24/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Muscle Twitching Other Serious 11/14/2008 60 Male 2/25/2009 Physician Norway
Primary
Secondary
Concomitant
Renal Impairment Other Serious 12/30/2008 64 Female 2/25/2009 Physician Norway
Primary
Secondary
Concomitant
Muscle Twitching Other Serious 11/14/2008 3/11/2009 Physician Norway
Primary
Secondary
Concomitant
Sepsis Other Serious 12/19/2008 59 Male 146 lb 3/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 10/26/2007 Male 162 lb 3/30/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Lymphopenia Other Serious 4/27/2009 Male 176 lb 5/12/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 3/19/2009 52 5/27/2009 Other Health Professional United Kingdom
Primary
Concomitant
Gastric Perforation Life Threatening 7/19/2008 Male 6/2/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 1/1/2009 Male 7/14/2009 Pharmacist United States
Primary
Concomitant
Intestinal Perforation Other Serious 8/7/2008 64 Female 7/14/2009 Other Health Professional United States
Primary
Concomitant
Joint Swelling Hospitalization 1/1/2009 Female 7/21/2009 Pharmacist Ireland
Primary
Secondary
Concomitant
Vomiting Other Serious 7/1/2009 57 Male 7/30/2009 Other Health Professional United States
Primary
Concomitant
Intentional Drug Misuse Other Serious Female 8/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Joint Swelling Hospitalization 1/1/2009 Female 8/26/2009 Pharmacist Ireland
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 7/5/2009 Male 8/31/2009 Netherlands
Primary
Concomitant
Central Line Infection Hospitalization 8/12/2009 Male 9/4/2009 Physician United Kingdom
Primary
Concomitant
Vitreous Haemorrhage Other Serious 4/1/2009 65 Male 9/15/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Life Threatening 6/20/2009 63 Male 107 lb 9/10/2009 Physician Korea, Republic Of
Primary
Concomitant
Renal Failure Chronic Hospitalization 9/7/2008 53 Male 243 lb 9/14/2009 United States
Primary
Concomitant
Central Line Infection Hospitalization 8/12/2009 Male 9/28/2009 Physician United Kingdom
Primary
Concomitant
Night Sweats 1/1/2007 60 Female 10/2/2009 Consumer United States
Primary
Concomitant
Spinal Column Stenosis Hospitalization 9/7/2008 53 Male 9/28/2009 United States
Primary
Concomitant
Spinal Fracture Hospitalization 1/1/2009 Male 10/14/2009 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 9/7/2008 53 Male 243 lb 10/9/2009 United States
Primary
Concomitant
Wheezing Hospitalization 9/7/2008 53 Male 243 lb 10/27/2009 United States
Primary
Concomitant
Weight Bearing Difficulty Hospitalization 11/1/2009 Male 11/12/2009 Canada
Primary
Concomitant
Gastric Perforation Life Threatening 7/19/2008 Male 11/12/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Bearing Difficulty Hospitalization 11/1/2009 Male 11/12/2009 Canada
Primary
Concomitant
Urinary Incontinence Other Serious 1/1/2004 Male 174 lb 11/16/2009 United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 1/1/2009 76 Male 11/17/2009 Physician United States
Primary
Secondary
Concomitant
Vocal Cord Disorder Hospitalization 7/15/2009 63 Male 190 lb 11/20/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thirst Decreased Hospitalization 6/1/2009 63 Male 11/25/2009 Other Health Professional United Kingdom
Primary
Concomitant

Drug Data