Lactulose combined with Norvasc

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Somnolence Life Threatening 11/5/2005 68 Female 249 lb 1/3/2006 Germany
Primary
Concomitant
Weight Increased Hospitalization 1/1/2001 72 Male 223 lb 1/9/2006 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 1/1/2006 49 Female 138 lb 2/16/2006 Pharmacist United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2001 72 Male 223 lb 2/27/2006 Physician United States
Primary
Concomitant
Osteonecrosis Other Serious 12/1/2005 70 Female 3/2/2006 Physician Italy
Primary
Concomitant
Schizoaffective Disorder Hospitalization Female 3/30/2006 Lawyer Germany
Primary
Concomitant
Oedema Peripheral Hospitalization 8/1/2000 79 Female 176 lb 4/24/2006 Physician United States
Primary
Concomitant
Ammonia Increased Hospitalization 2/14/2006 Male 211 lb 4/6/2006 Physician United States
Primary
Concomitant
White Blood Cells Urine Positive Hospitalization 1/9/2006 86 Female 100 lb 6/22/2006 Physician United States
Primary
Concomitant
Leukopenia Other Serious 5/12/2006 62 Female 185 lb 6/29/2006 Physician Germany
Primary
Secondary
Concomitant
Leukopenia Other Serious 5/12/2006 62 Female 185 lb 7/13/2006 Physician Germany
Primary
Secondary
Concomitant
International Normalised Ratio Increased 5/1/2005 73 Male 247 lb 8/1/2006 Consumer United States
Primary
Concomitant
Therapeutic Response Decreased 1/1/2006 Female 8/9/2006 Other Health Professional United States
Primary
Concomitant
Drug Ineffective Other Serious 5/17/2006 82 Female 8/4/2006 United States
Primary
Concomitant
Pancytopenia Hospitalization 1/10/2006 90 Male 8/11/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 6/23/2006 68 Male 143 lb 9/5/2006 Physician Japan
Primary
Concomitant
Haemoptysis 71 Female 136 lb 7/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 3/14/2006 58 Male 185 lb 9/6/2006 Physician Germany
Primary
Secondary
Concomitant
Protein Total Decreased Other Serious 1/1/2006 Female 9/15/2006 Other Health Professional United States
Primary
Concomitant
Transaminases Increased Other Serious 3/14/2006 58 Male 185 lb 9/20/2006 Physician Germany
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 1/1/2005 Female 140 lb 11/17/2006 Consumer United States
Primary
Concomitant
Paraesthesia Oral Life Threatening 8/31/2006 27 Male 139 lb 11/10/2006 Pharmacist United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 6/23/2006 68 Male 143 lb 11/27/2006 Physician Japan
Primary
Concomitant
Vomiting Other Serious 2/7/2003 2 Female 23 lb 11/29/2006 United States
Primary
Secondary
Concomitant
Delusion Other Serious 80 Female 12/8/2006 Pharmacist Canada
Primary
Concomitant
Delusion Other Serious 80 Female 12/8/2006 Pharmacist Canada
Primary
Concomitant
Oral Intake Reduced Hospitalization 5/1/2006 67 Male 12/8/2006 Physician Netherlands
Primary
Secondary
Concomitant
Neutrophil Count Decreased Life Threatening 12/7/2006 Male 12/28/2006 Pharmacist United States
Primary
Concomitant
Weight Increased Hospitalization 9/1/2005 52 Male 183 lb 3/16/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Required Intervention 11/1/2006 79 Male 3/29/2007 Canada
Primary
Concomitant
Tooth Loss Other Serious 1/1/2005 Female 127 lb 4/11/2007 United States
Primary
Concomitant
Post Procedural Complication Hospitalization 2/26/2007 Female 134 lb 5/22/2007 Physician United States
Primary
Concomitant
Post Procedural Complication Hospitalization 2/26/2007 Female 134 lb 6/5/2007 Physician United States
Primary
Concomitant
Vitamin D Deficiency Other Serious 1/1/2004 Male 159 lb 6/22/2007 Other Health Professional United States
Primary
Concomitant
Post Procedural Complication Hospitalization 2/26/2007 Female 134 lb 6/25/2007 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 5/18/2007 69 Male 137 lb 7/31/2007 Physician Canada
Primary
Concomitant
Alveolitis Other Serious 8/28/2006 Female 8/6/2007 Germany
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/1/2006 79 Male 8/9/2007 Canada
Primary
Concomitant
Vitamin D Deficiency Other Serious 1/1/2004 Male 159 lb 8/22/2007 Other Health Professional United States
Primary
Concomitant
Vitamin D Deficiency Other Serious 1/1/2004 Male 159 lb 8/31/2007 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/1/2006 79 Male 8/27/2007 Other Health Professional Canada
Primary
Concomitant
Alveolitis Other Serious 8/28/2006 Female 9/6/2007 Germany
Primary
Concomitant
Alveolitis Other Serious 8/28/2006 Female 9/20/2007 Germany
Primary
Concomitant
Tongue Ulceration Other Serious 9/8/2004 Male 243 lb 10/5/2007 Physician Germany
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 11/1/2006 Female 11/5/2007 Physician United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 11/1/2006 Female 12/11/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Death 10/26/2007 50 Female 223 lb 12/11/2007 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/16/2007 60 Female 140 lb 12/13/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/16/2007 60 Female 140 lb 1/3/2008 Physician United States
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 12/7/2007 Male 1/31/2008 Pharmacist Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 1/12/2008 83 Female 2/2/2008 Other Health Professional United States
Primary
Concomitant
Retinal Detachment Hospitalization 10/23/2007 66 Male 165 lb 2/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 10/26/2007 50 Female 223 lb 1/31/2008 Other Health Professional United States
Primary
Concomitant
Vomiting Death 1/17/2008 66 Male 2/13/2008 Canada
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 12/18/2002 76 Male 2/14/2008 Physician Germany
Primary
Secondary
Renal Failure Hospitalization 1/1/2008 73 Female 112 lb 2/28/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 1/5/2003 67 Female 2/29/2008 Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 12/18/2002 76 Male 2/26/2008 Physician Germany
Primary
Secondary
Pyrexia Hospitalization 1/12/2008 83 Female 164 lb 3/4/2008 Other Health Professional United States
Primary
Concomitant
Vomiting Death 1/17/2008 66 Male 3/7/2008 Canada
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 11/1/2002 Male 3/3/2008 Physician Germany
Primary
Secondary
Psoriasis Hospitalization 12/7/2007 Male 3/14/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 5/1/2007 Male 220 lb 3/11/2008 Physician Denmark
Primary
Concomitant
Renal Failure Acute Other Serious 1/1/2004 84 Female 143 lb 3/27/2008 Physician United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 12/18/2002 76 Male 4/10/2008 Physician Germany
Primary
Secondary
Pyrexia Hospitalization 1/12/2008 83 Female 164 lb 4/25/2008 Other Health Professional United States
Primary
Concomitant
Leukopenia Other Serious 5/12/2006 62 Female 185 lb 4/29/2008 Physician Germany
Primary
Secondary
Concomitant
Renal Impairment Other Serious 3/1/2007 45 Male 5/23/2008 Consumer Canada
Primary
Secondary
Concomitant
Renal Impairment Other Serious 3/1/2007 45 Male 5/28/2008 Consumer Canada
Primary
Secondary
Concomitant
Haemorrhage Death 5/1/2008 74 Female 5/29/2008 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 11/4/2005 Male 6/13/2008 Pharmacist
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 11/23/2007 67 Male 246 lb 6/6/2008 Physician Australia
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/1/2007 70 Male 137 lb 7/8/2008 Physician Canada
Primary
Concomitant
Haemorrhage Other Serious 5/1/2008 74 Female 7/21/2008 Pharmacist United States
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Life Threatening 7/16/2003 Female 123 lb 7/28/2008 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2008 Female 170 lb 8/1/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/1/2007 70 Male 137 lb 8/15/2008 Physician Canada
Primary
Concomitant
Vomiting Other Serious 1/1/2007 47 Male 9/24/2008 Lawyer United States
Primary
Concomitant
Urinary Incontinence Other Serious 1/1/2007 73 Female 8/27/2007 Physician United States
Primary
Concomitant
Loss Of Consciousness Other Serious 10/22/2008 63 Male 11/14/2008 Physician United States
Primary
Concomitant
Overdose Hospitalization 7/23/2008 63 Male 190 lb 10/27/2008 Physician United States
Primary
Concomitant
Stem Cell Transplant 5/28/2003 74 Female 167 lb 11/26/2008 Physician United States
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2007 Male 110 lb 12/23/2008 Physician United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 1/5/2009 Male 1/26/2009 Physician United States
Primary
Concomitant
Thrombosis Other Serious 8/1/2007 Female 157 lb 1/28/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypertension Other Serious 9/15/2004 Female 134 lb 3/26/2009 Germany
Primary
Concomitant
Hypertension Other Serious 9/15/2004 Female 134 lb 3/27/2009 Germany
Primary
Concomitant
Hypertension Hospitalization 9/15/2004 Female 134 lb 4/14/2009 Germany
Primary
Concomitant
Haemoglobin Decreased Hospitalization 1/1/2009 Male 4/16/2009 Physician United States
Primary
Concomitant
Syncope Hospitalization 2/23/2009 45 Male 5/21/2009 Physician United States
Primary
Concomitant
Palpitations Hospitalization 4/1/2009 Female 148 lb 5/20/2009 Pharmacist United States
Primary
Concomitant
Hypertension Hospitalization 9/15/2004 Female 134 lb 6/5/2009 Germany
Primary
Concomitant
Urinoma Hospitalization 11/13/2004 Male 163 lb 6/23/2009 Physician Canada
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 7/10/2003 Male 6/25/2009 Physician Germany
Primary
Secondary
Concomitant
Somnolence Other Serious 8/18/2003 Male 6/25/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Incorrect Route Of Drug Administration Male 6/29/2009 Pharmacist United States
Primary
Concomitant
Haemorrhage Other Serious 5/1/2008 74 Female 7/22/2009 Consumer United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 9/5/2008 Female 106 lb 7/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 9/5/2008 Female 106 lb 7/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Oedema Peripheral Life Threatening 3/1/2008 79 Female 7/23/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Haemorrhage Other Serious 5/1/2008 74 Female 7/22/2009 Consumer United States
Primary
Secondary
Concomitant
Ureteric Stenosis Required Intervention 7/10/2003 69 Male 8/13/2009 Physician Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 80 Female 9/3/2009 United States
Primary
Concomitant
Weight Increased Other Serious 80 Female 9/4/2009 Lawyer United States
Primary
Concomitant
Hypertensive Crisis Hospitalization 9/15/2004 Female 134 lb 9/16/2009 Germany
Primary
Concomitant
Surgery Hospitalization 78 Female 9/17/2009 United States
Primary
Concomitant
Spinal Column Stenosis Hospitalization 9/7/2008 53 Male 9/28/2009 United States
Primary
Concomitant
Fluid Retention Hospitalization Female 170 lb 10/13/2009 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 9/7/2008 53 Male 243 lb 10/9/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 66 Male 10/18/2009 United States
Primary
Concomitant
Surgery Hospitalization 78 Female 10/18/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 80 Female 10/22/2009 Lawyer United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 78 Female 10/26/2009 United States
Primary
Concomitant
Wheezing Hospitalization 9/7/2008 53 Male 243 lb 10/27/2009 United States
Primary
Concomitant
Influenza Death 11/5/2009 69 Female 11/11/2009 Pharmacist Canada
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 78 Female 11/4/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 66 Male 11/4/2009 United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 78 Female 11/16/2009 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 9/15/2009 Male 167 lb 12/2/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 66 Male 12/1/2009 United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 78 Female 12/1/2009 Lawyer United States
Primary
Concomitant
Duodenal Ulcer Haemorrhage Hospitalization 6/29/2009 69 Male 12/15/2009 Other Health Professional Germany
Primary
Concomitant
Renal Failure Acute Hospitalization 8/19/2009 Male 167 lb 12/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 11/5/2009 Female 12/31/2009 Physician Canada
Primary
Concomitant
Hepatic Encephalopathy Hospitalization 12/14/2009 80 Female 119 lb 1/12/2010 Physician Japan
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 78 Female 1/11/2010 United States
Primary
Concomitant
Duodenal Ulcer Haemorrhage Hospitalization 6/29/2009 69 Male 2/1/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Pleural Effusion Death 12/18/2008 80 Male 2/2/2010 Physician Canada
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 66 Male 1/22/2010 United States
Primary
Concomitant
Pneumonia Hospitalization 2/3/2010 63 Male 2/12/2010 Physician Germany
Primary
Concomitant
Infection Hospitalization Male 2/17/2010 Consumer United States
Primary
Concomitant
Cellulitis Hospitalization Male 2/19/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Hospitalization 2/4/2010 63 Male 2/25/2010 Physician Germany
Primary
Concomitant
Hypertensive Crisis Hospitalization 9/15/2004 Female 134 lb 2/25/2010 Germany
Primary
Concomitant
Renal Failure Other Serious 73 Female 3/25/2010 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious Female 5/7/2010 Physician Canada
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 78 Female 117 lb 4/26/2010 United States
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 1/21/2009 45 Male 5/12/2010 Physician Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 3/6/2009 72 Female 5/13/2010 Physician Germany
Primary
Secondary
Skin Lesion Other Serious 2/2/2006 51 Female 201 lb 5/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Lesion Other Serious 2/2/2006 51 Female 201 lb 5/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/22/2007 68 Male 5/24/2010 Physician United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 8/31/2009 67 Female 123 lb 6/9/2010 Physician Japan
Primary
Concomitant
Hyperkalaemia Life Threatening 12/1/2008 79 Female 152 lb 6/10/2010 Physician Germany
Primary
Secondary
Concomitant
Interacting
Pain In Extremity Other Serious 12/31/2008 87 Male 6/11/2010 Consumer United States
Primary
Concomitant
Sensation Of Heaviness Other Serious 62 Male 187 lb 6/14/2010 Pharmacist Canada
Primary
Concomitant
Hyperkalaemia Life Threatening 12/1/2008 79 Female 152 lb 6/18/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Hyperkalaemia Life Threatening 12/1/2008 79 Female 152 lb 6/21/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Oedema Peripheral Life Threatening 12/1/2008 79 Female 152 lb 6/21/2010 Germany
Primary
Secondary
Concomitant
Nausea 8/1/2008 64 Female 145 lb 7/22/2010 Consumer United States
Primary
Concomitant
Interacting

Drug Data