Lactulose combined with Morphine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pulmonary Haemorrhage Death 10/7/2004 50 9/12/2005 Physician United States
Primary
Concomitant
Rales Life Threatening 11/11/2005 85 Female 1/23/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/7/2005 58 Female 1/27/2006 Norway
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 12/16/2005 53 Male 176 lb 2/17/2006 Other Health Professional Canada
Primary
Concomitant
Platelet Count Decreased Hospitalization 10/10/2005 84 Female 148 lb 1/16/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2000 70 Female 146 lb 3/28/2006 Lawyer United States
Primary
Concomitant
Tooth Fracture Other Serious 1/7/2005 58 Female 4/5/2006 Norway
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2000 70 Female 146 lb 4/10/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 9/1/2001 70 Female 126 lb 4/14/2006 Physician Canada
Primary
Concomitant
Ventricular Tachycardia Other Serious 3/1/2006 44 Male 134 lb 4/11/2006 Pharmacist United States
Primary
Concomitant
Subileus Hospitalization 12/19/2005 69 Male 148 lb 4/18/2006 Consumer United States
Primary
Secondary
Concomitant
Subileus Hospitalization 12/19/2005 69 Male 148 lb 4/27/2006 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 6/22/2005 45 Female 150 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 4/17/2006 68 Male 136 lb 4/27/2006 Physician Malaysia
Primary
Concomitant
Loss Of Consciousness Required Intervention 12/13/2005 53 Male 169 lb 3/1/2006 United States
Primary
Concomitant
Tooth Fracture Other Serious 1/7/2005 58 Female 5/17/2006 Norway
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/17/2006 68 Male 136 lb 5/17/2006 Physician Malaysia
Primary
Concomitant
Varices Oesophageal Other Serious 5/6/2006 Female 5/24/2006 Physician United States
Primary
Concomitant
Tooth Fracture Other Serious 1/7/2005 58 Female 5/23/2006 Norway
Primary
Secondary
Concomitant
White Blood Cell Disorder Other Serious 1/16/2006 60 Female 6/8/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Shock Death 46 Male 176 lb 6/15/2006 Physician Sweden
Primary
Secondary
Concomitant
Shock Death 46 Male 176 lb 6/22/2006 Sweden
Primary
Secondary
Concomitant
Myoclonus Hospitalization 4/23/2006 Male 7/18/2006 Pharmacist United States
Primary
Concomitant
Metastases To Spleen Death 5/25/2006 Female 7/12/2006 Other Health Professional United States
Primary
Concomitant
Shock Other Serious 46 Male 176 lb 7/31/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Hip Fracture Hospitalization 76 Male 8/9/2006 Pharmacist New Zealand
Primary
Concomitant
Pneumatosis Intestinalis Hospitalization 6/22/2006 70 Male 142 lb 7/26/2006 Canada
Primary
Secondary
Concomitant
Pneumatosis Intestinalis Hospitalization 6/22/2006 70 Male 142 lb 8/10/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Hepatic Enzyme Abnormal Other Serious 6/14/2006 56 Male 162 lb 6/14/2006 Pharmacist United States
Primary
Concomitant
Urinary Retention Other Serious 6/12/2006 56 Male 162 lb 6/12/2006 Pharmacist United States
Primary
Concomitant
Shock Death 11/23/2005 46 Male 8/30/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Pain In Extremity Life Threatening 1/26/2006 69 Male 9/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Depression Death 46 Male 176 lb 9/15/2006 Other Health Professional Sweden
Primary
Concomitant
Interacting
Shock Other Serious 46 Male 176 lb 9/14/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Small Intestinal Obstruction Other Serious 4/4/2005 76 Male 10/2/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Aspiration Death 9/19/2006 90 Male 10/11/2006 United States
Primary
Concomitant
Tendonitis Other Serious 10/1/2004 68 Male 10/12/2006 Physician Sweden
Primary
Secondary
Concomitant
Hypotension 5/2/2006 Male 10/23/2006 Pharmacist United States
Primary
Concomitant
Sepsis Hospitalization 9/7/2006 Male 155 lb 10/31/2006 Consumer United States
Primary
Concomitant
Tachycardia Hospitalization 5/2/2003 55 Male 238 lb 11/6/2006 Physician United States
Primary
Secondary
Concomitant
Paraesthesia Oral Life Threatening 8/31/2006 27 Male 139 lb 11/10/2006 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 10/16/2006 60 Male 159 lb 11/10/2006 Physician Slovakia (Slovak Republic)
Primary
Concomitant
Intestinal Infarction Death 2/9/2006 Male 170 lb 11/29/2006 Physician
Primary
Concomitant
Pain In Extremity Life Threatening 1/26/2006 69 Male 12/1/2006 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 10/16/2006 60 Male 159 lb 11/28/2006 Physician Slovakia (Slovak Republic)
Primary
Concomitant
Hypothyroidism Hospitalization 7/5/2006 52 Female 149 lb 11/28/2006 Physician Germany
Primary
Concomitant
Myocardial Infarction Death 3/26/2006 Female 267 lb 12/28/2006 United States
Primary
Concomitant
Intestinal Obstruction Hospitalization 10/29/2006 52 Female 123 lb 12/22/2006 Physician Australia
Primary
Secondary
Concomitant
Hyperthyroidism Hospitalization 2/17/2006 72 Male 183 lb 1/15/2007 Physician France
Primary
Concomitant
Intestinal Obstruction Hospitalization 10/29/2006 52 Female 123 lb 1/12/2007 Physician Australia
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 10/29/2006 52 Female 123 lb 1/18/2007 Physician Australia
Primary
Secondary
Concomitant
Sepsis Life Threatening 1/14/2007 Male 353 lb 2/5/2007 Physician Australia
Primary
Concomitant
Intestinal Infarction Hospitalization 1/31/2006 Male 170 lb 2/7/2007 Physician
Primary
Concomitant
Sepsis Life Threatening 1/14/2007 Male 353 lb 2/13/2007 Physician Australia
Primary
Concomitant
Fatigue Hospitalization 12/19/2006 84 Male 2/15/2007 Pharmacist United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 1/14/2007 Male 353 lb 2/26/2007 Physician Australia
Primary
Concomitant
Pneumonia Hospitalization 2/18/2007 Male 97 lb 3/7/2007 Korea, Republic Of
Primary
Concomitant
Wound Infection Life Threatening 1/14/2007 Male 353 lb 3/9/2007 Physician Australia
Primary
Concomitant
Loss Of Consciousness Life Threatening 1/26/2006 69 Male 3/13/2007 Consumer United States
Primary
Secondary
Concomitant
Oral Candidiasis Other Serious 76 Female 8/2/2006 United States
Primary
Concomitant
Oral Candidiasis Other Serious 76 Female 8/2/2006 United States
Primary
Concomitant
Pneumonia Hospitalization 2/18/2007 Male 97 lb 3/19/2007 Korea, Republic Of
Primary
Concomitant
Pneumonia Hospitalization 2/18/2007 Male 97 lb 4/2/2007 Korea, Republic Of
Primary
Concomitant
Wound Infection Life Threatening 1/14/2007 Male 353 lb 4/11/2007 Physician Australia
Primary
Concomitant
Vomiting Hospitalization 3/26/2007 Male 209 lb 4/10/2007 Pharmacist United States
Primary
Concomitant
Hepatitis Other Serious 2/15/2007 Female 4/17/2007 Physician Germany
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 3/13/2006 59 Male 4/20/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Wound Infection Life Threatening 1/14/2007 Male 353 lb 4/23/2007 Physician Australia
Primary
Concomitant
Hepatitis Other Serious 2/15/2007 64 Female 238 lb 4/24/2007 Physician Germany
Primary
Concomitant
Wound Hospitalization 12/25/2002 20 Male 4/11/2007 Physician United States
Primary
Secondary
Concomitant
Wound Infection Life Threatening 1/14/2007 Male 353 lb 5/1/2007 Physician Australia
Primary
Concomitant
Peritonitis Sclerosing Hospitalization 3/13/2006 59 Male 5/4/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Small Intestinal Haemorrhage Life Threatening 4/24/2005 44 Female 5/9/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Wound Infection Life Threatening 1/14/2007 Male 353 lb 5/14/2007 Physician Australia
Primary
Concomitant
Stent Placement Other Serious 10/1/2005 Male 5/25/2007 United States
Primary
Concomitant
Shock Death 46 Male 176 lb 5/15/2007 Sweden
Primary
Secondary
Concomitant
Wound Infection Life Threatening 1/14/2007 Male 353 lb 5/29/2007 Physician Australia
Primary
Concomitant
Wound Infection Life Threatening 1/14/2007 Male 353 lb 5/29/2007 Physician Australia
Primary
Concomitant
Thrombocytopenia Death 72 Male 6/4/2007 Consumer Canada
Primary
Secondary
Concomitant
Stent Placement Other Serious 10/1/2005 Male 6/7/2007 United States
Primary
Concomitant
Tremor Hospitalization 6/3/2007 Female 114 lb 6/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Hospitalization 6/3/2007 59 Female 115 lb 6/8/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/1/2007 64 Female 238 lb 6/18/2007 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/1/2007 64 Female 238 lb 7/5/2007 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9 Male 7/10/2007 Other Health Professional Sweden
Primary
Concomitant
Lipase Increased Other Serious 8/29/2006 56 Female 7/23/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Troponin Increased Other Serious Male 159 lb 7/24/2007 Physician Australia
Primary
Concomitant
Subdural Haematoma Hospitalization 6/13/2006 61 Male 199 lb 1/15/2007 Physician United States
Primary
Concomitant
Wound Infection Life Threatening 1/14/2007 Male 353 lb 8/2/2007 Physician Australia
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9 Male 8/3/2007 Other Health Professional Sweden
Primary
Concomitant
Postoperative Wound Infection Hospitalization 2/5/2004 75 Female 176 lb 8/1/2007 Other Health Professional Germany
Primary
Concomitant
Jaundice Hospitalization Male 92 lb 8/24/2007 Pharmacist United Kingdom
Primary
Concomitant
Vision Blurred Hospitalization 6/8/2007 Male 107 lb 6/11/2007 Pharmacist United States
Primary
Concomitant
Pneumonia Hospitalization 2/18/2007 Male 97 lb 8/30/2007 Korea, Republic Of
Primary
Concomitant
Death Death 5/1/2007 Male 183 lb 9/5/2007 United States
Primary
Concomitant
Death Death 5/1/2007 Male 183 lb 9/11/2007 United States
Primary
Concomitant
Wound Infection Bacterial Hospitalization 2/5/2004 75 Female 176 lb 9/10/2007 Consumer Germany
Primary
Concomitant
Neuroleptic Malignant Syndrome Required Intervention 1/1/2007 77 Female 9/4/2007 Physician United States
Primary
Concomitant
Wound Infection Bacterial Hospitalization 2/5/2004 75 Female 176 lb 9/18/2007 Consumer Germany
Primary
Concomitant
Toxic Epidermal Necrolysis Required Intervention 10 Male 9/17/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Pancytopenia Other Serious 3/1/2001 44 Male 9/26/2007 Other Health Professional Australia
Primary
Concomitant
Spinal Column Stenosis Hospitalization 2/5/2004 75 Female 176 lb 9/20/2007 Germany
Primary
Concomitant
Malignant Neoplasm Progression Hospitalization 8/1/2007 65 Male 179 lb 10/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Hospitalization 2/23/2007 97 Female 10/8/2007 Pharmacist United States
Primary
Concomitant
Wound Infection Bacterial Hospitalization 2/5/2004 75 Female 176 lb 10/10/2007 Consumer Germany
Primary
Concomitant
Dyspnoea Other Serious 10/15/2007 48 Male 121 lb 10/18/2007 Physician Singapore
Primary
Secondary
Concomitant
Thrombosis In Device Required Intervention 7/14/2007 61 Male 8/1/2007 United States
Primary
Concomitant
Vision Blurred Hospitalization 6/8/2007 Male 98 lb 6/20/2007 United States
Primary
Concomitant
Vomiting Other Serious 10/15/2007 48 Male 121 lb 10/22/2007 Physician Singapore
Primary
Secondary
Concomitant
Death Death 5/23/2007 Male 183 lb 11/2/2007 United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 10 Male 11/8/2007 Sweden
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 11/6/2007 Female 165 lb 11/21/2007 United Kingdom
Primary
Concomitant
Bowel Movement Irregularity Hospitalization 8/29/2007 71 Male 11/30/2007 Physician Sweden
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 11/6/2007 Female 165 lb 12/5/2007 United Kingdom
Primary
Concomitant
Constipation Hospitalization 8/29/2007 71 Male 12/6/2007 Physician Sweden
Primary
Secondary
Concomitant
Pruritus Other Serious 4/1/2007 Female 174 lb 12/13/2007 Consumer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 10 Male 12/14/2007 Sweden
Primary
Secondary
Concomitant
Convulsion Other Serious 7/22/2007 67 Male 12/21/2007 Other Health Professional Sweden
Primary
Concomitant
Constipation Hospitalization 8/29/2007 71 Male 1/23/2008 Physician Sweden
Primary
Secondary
Concomitant
Death Death 5/23/2007 Male 183 lb 2/5/2008 United States
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 12/18/2002 76 Male 2/14/2008 Physician Germany
Primary
Secondary
Hypocalcaemia 11/13/2007 53 Male 11/15/2007 Physician United States
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 12/18/2002 76 Male 2/26/2008 Physician Germany
Primary
Secondary
Liver Function Test Abnormal Other Serious 11/6/2007 Female 165 lb 3/4/2008 United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 11/1/2002 Male 3/3/2008 Physician Germany
Primary
Secondary
Vomiting Other Serious 1/1/2007 80 Female 96 lb 3/12/2008 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2007 79 Female 108 lb 3/21/2008 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 3/20/2008 Male 3/20/2008 Pharmacist United States
Primary
Secondary
Concomitant
Self-injurious Ideation Other Serious Male 193 lb 4/10/2008 United States
Primary
Concomitant
Peritonitis Hospitalization 3/15/2008 71 Male 201 lb 4/10/2008 Physician United States
Primary
Concomitant
Malaise Other Serious Male 179 lb 4/11/2008 Physician Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 12/18/2002 76 Male 4/10/2008 Physician Germany
Primary
Secondary
Spinal Disorder Other Serious Male 179 lb 4/22/2008 Physician Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 10/18/2007 67 Female 5/7/2008 Physician Ireland
Primary
Secondary
Concomitant
Respiratory Failure Death 6/8/2005 Male 176 lb 5/8/2008 Sweden
Primary
Concomitant
Interacting
Trismus Other Serious 10/4/2007 69 Male 243 lb 4/29/2008 Other Health Professional Germany
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 67 Female 5/7/2008 Ireland
Primary
Secondary
Concomitant
Tachycardia Death 1/7/2008 68 Female 5/16/2008 Pharmacist United States
Primary
Concomitant
Septic Shock Hospitalization 12/1/2007 Male 124 lb 5/20/2008 Belgium
Primary
Concomitant
Transaminases Increased Life Threatening 1/1/2008 67 Female 172 lb 5/21/2008 Physician Germany
Primary
Concomitant
Haemorrhage Death 5/1/2008 74 Female 5/29/2008 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/26/2008 65 Male 151 lb 5/16/2008 Physician Canada
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 10/19/2007 67 Female 5/21/2008 Ireland
Primary
Secondary
Concomitant
Neutropenia Disability 4/1/2008 56 Male 130 lb 5/27/2008 Pharmacist United States
Primary
Concomitant
Drug Interaction Hospitalization 10/17/2006 54 Male 179 lb 6/10/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachycardia Other Serious 1/7/2008 68 Female 6/10/2008 Pharmacist United States
Primary
Concomitant
Depressed Level Of Consciousness Required Intervention 4/24/2008 82 Male 5/2/2008 Pharmacist United States
Primary
Secondary
Concomitant
Death Death 5/23/2007 Male 183 lb 6/18/2008 United States
Primary
Concomitant
Urinary Tract Infection Staphylococcal Other Serious 8/2/2007 50 Female 6/23/2008 Physician United Kingdom
Primary
Concomitant
Self-injurious Ideation Other Serious 12/1/2007 Male 193 lb 7/1/2008 United States
Primary
Concomitant

Drug Data