Lactulose combined with Morphine Sulfate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Somnolence Life Threatening 11/5/2005 68 Female 249 lb 1/3/2006 Germany
Primary
Concomitant
Ischaemic Stroke Disability 7/7/2004 Female 2/9/2006 United Kingdom
Primary
Concomitant
Urinary Retention Other Serious 93 Male 2/16/2006 Physician Netherlands
Primary
Concomitant
Vomiting Hospitalization 6/7/2005 46 Female 2/24/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 8/1/2001 76 Female 99 lb 2/24/2006 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 8/1/2001 76 Female 99 lb 3/2/2006 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/7/2005 55 Male 185 lb 2/27/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Cell Carcinoma Stage Unspecified Death 1/19/2006 55 Male 218 lb 2/28/2006 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/17/2003 37 Male 152 lb 3/14/2006 United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2000 70 Female 146 lb 3/28/2006 Lawyer United States
Primary
Concomitant
Hypertension Life Threatening 10/20/2005 Male 201 lb 3/31/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2000 70 Female 146 lb 4/10/2006 Physician United States
Primary
Concomitant
Wheezing Other Serious 2/23/1997 44 Male 219 lb 4/4/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 9/1/2001 70 Female 126 lb 4/14/2006 Physician Canada
Primary
Concomitant
Renal Failure Life Threatening 3/16/2006 56 88 lb 4/7/2006 Physician Korea, Republic Of
Primary
Concomitant
Renal Impairment Hospitalization 4/4/2006 57 Male 181 lb 4/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Life Threatening 3/16/2006 56 Female 88 lb 4/18/2006 Physician Korea, Republic Of
Primary
Concomitant
Myocardial Infarction Death 3/26/2006 Female 267 lb 5/4/2006 United States
Primary
Concomitant
Stomatitis Hospitalization 3/27/2006 Male 5/8/2006 Physician Germany
Primary
Secondary
Concomitant
Skin Lesion Hospitalization 4/4/2006 57 Male 181 lb 5/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Skin Ulcer Hospitalization 4/4/2006 57 Male 181 lb 5/15/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hallucination, Visual Other Serious 4/1/2005 80 Female 154 lb 5/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Feeling Drunk Hospitalization 5/10/2005 52 Female 152 lb 5/25/2006 Pharmacist United Kingdom
Primary
Concomitant
Purulence Life Threatening 4/24/2006 52 Male 164 lb 6/6/2006 United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 10/6/1997 Male 6/7/2006 Physician United States
Primary
Concomitant
Mental Status Changes Life Threatening 2/3/2006 30 Female 97 lb 7/10/2006 Physician Korea, Republic Of
Primary
Concomitant
Ischaemic Stroke Other Serious 7/7/2004 Female 8/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Platelet Count Decreased Hospitalization 7/10/2006 53 Male 8/21/2006 Physician France
Primary
Secondary
Concomitant
Pain In Extremity Life Threatening 1/26/2006 69 Male 9/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Thrombosis Hospitalization 4/26/2006 59 Male 10/9/2006 Physician Germany
Primary
Concomitant
Tendonitis Other Serious 10/1/2004 68 Male 10/12/2006 Physician Sweden
Primary
Secondary
Concomitant
Proctalgia Other Serious 10/6/2006 70 Male 172 lb 10/24/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Overdose Other Serious 74 Male 10/26/2006 Other Health Professional United Kingdom
Primary
Concomitant
Perianal Abscess Other Serious 10/6/2006 70 Male 172 lb 11/6/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Death 3/26/2006 Female 267 lb 11/21/2006 United States
Primary
Concomitant
Pain In Extremity Life Threatening 1/26/2006 69 Male 12/1/2006 Consumer United States
Primary
Secondary
Concomitant
Urethral Haemorrhage Other Serious 10/30/2006 Male 181 lb 12/4/2006 Physician Czech Republic
Primary
Concomitant
Hypothyroidism Hospitalization 7/5/2006 52 Female 149 lb 11/28/2006 Physician Germany
Primary
Concomitant
Pulmonary Embolism Hospitalization 10/4/2006 69 Male 172 lb 12/12/2006 Physician New Zealand
Primary
Secondary
Concomitant
Leukocytoclastic Vasculitis Other Serious 12/1/2006 58 Male 157 lb 1/3/2007 Physician Korea, Republic Of
Primary
Concomitant
Hypotension 8/8/2006 50 Male 106 lb 10/24/2006 United States
Primary
Concomitant
Malaise Hospitalization 11/29/2006 88 Male 1/10/2007 United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 10/4/2006 69 Male 172 lb 2/1/2007 Physician New Zealand
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 12/30/2006 78 Male 242 lb 1/18/2007 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Life Threatening 10/21/2006 Male 118 lb 2/12/2007 United Kingdom
Primary
Concomitant
Loss Of Consciousness Life Threatening 1/26/2006 69 Male 3/13/2007 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 39 Male 11/13/2006 Physician United States
Primary
Concomitant
Haemorrhage Hospitalization 3/27/2006 Female 130 lb 4/11/2007 Consumer United Kingdom
Primary
Concomitant
Nausea Death 4/3/2007 41 Male 152 lb 5/2/2007 Other Health Professional United States
Primary
Concomitant
Small Intestinal Haemorrhage Life Threatening 4/24/2005 44 Female 5/9/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 3/16/2006 Female 88 lb 5/9/2007 Korea, Republic Of
Primary
Concomitant
Mental Disorder Life Threatening 2/1/2006 Female 97 lb 5/10/2007 Korea, Republic Of
Primary
Concomitant
Pneumonia Hospitalization 7/31/2006 Male 161 lb 6/22/2007 Poland
Primary
Concomitant
Vomiting Other Serious 12/25/2004 Female 110 lb 6/25/2007 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 7/31/2006 Male 161 lb 7/3/2007 Poland
Primary
Concomitant
Sepsis Other Serious 3/27/2006 Female 130 lb 7/20/2007 Consumer United Kingdom
Primary
Concomitant
Sepsis Other Serious 3/27/2006 Female 130 lb 7/30/2007 Consumer United Kingdom
Primary
Concomitant
Visual Disturbance Other Serious 6/27/2007 69 Male 8/1/2007 Pharmacist United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 7/31/2006 Male 161 lb 8/2/2007 Poland
Primary
Concomitant
Pneumonia Hospitalization 7/31/2006 Male 161 lb 8/8/2007 Poland
Primary
Concomitant
Renal Failure Hospitalization 3/16/2006 Female 88 lb 8/29/2007 Korea, Republic Of
Primary
Concomitant
Pneumonia Hospitalization 7/31/2006 Male 161 lb 9/26/2007 Poland
Primary
Concomitant
Ulcer Hospitalization 9/24/2007 Male 10/8/2007 United Kingdom
Primary
Concomitant
Syncope Life Threatening 7/11/2007 Female 190 lb 11/21/2007 Physician United States
Primary
Concomitant
Vomiting Other Serious 12/25/2004 Female 110 lb 1/15/2008 Consumer United States
Primary
Concomitant
Transaminases Increased Other Serious 2/21/2005 50 Male 115 lb 1/25/2008 Physician Poland
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 12/18/2002 76 Male 2/14/2008 Physician Germany
Primary
Secondary
Toxic Epidermal Necrolysis Hospitalization 12/18/2002 76 Male 2/26/2008 Physician Germany
Primary
Secondary
Toxic Epidermal Necrolysis Hospitalization 11/1/2002 Male 3/3/2008 Physician Germany
Primary
Secondary
Small Intestinal Obstruction Other Serious 67 Male 3/13/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Death Death 6/28/1989 63 Male 3/28/2008 Physician Canada
Primary
Concomitant
Drug Interaction Hospitalization 10/17/2006 54 Male 179 lb 5/6/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 10/17/2006 54 Male 179 lb 5/15/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/26/2008 65 Male 151 lb 5/16/2008 Physician Canada
Primary
Concomitant
Circulatory Collapse Death 6/4/2008 Male 6/16/2008 Physician Germany
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 10/16/2007 64 Male 6/16/2008 New Zealand
Primary
Concomitant
Post Procedural Haemorrhage Hospitalization 4/20/2008 63 Male 119 lb 6/23/2008 Other Health Professional United Kingdom
Primary
Concomitant
Circulatory Collapse Death 6/4/2008 Male 7/28/2008 Physician Germany
Primary
Concomitant
Sudden Death Death 10/5/2007 1 Male 15 lb 7/22/2008 Physician United Kingdom
Primary
Concomitant
Pharmaceutical Product Complaint Hospitalization 5/12/2008 52 Female 228 lb 7/30/2008 Consumer United States
Primary
Concomitant
Jaundice Cholestatic Death 8/1/2008 65 Female 8/26/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Jaundice Cholestatic Death 8/1/2008 65 Female 8/28/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1991 Male 188 lb 11/21/2008 United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 11/21/2008 Male 174 lb 12/1/2008 Belgium
Primary
Secondary
Concomitant
Oropharyngeal Blistering Other Serious 9/25/2008 84 Female 12/10/2008 Other Health Professional
Primary
Concomitant
Pulmonary Embolism Hospitalization 7/3/2008 12/12/2008 Other Health Professional Canada
Primary
Concomitant
Oropharyngeal Blistering Other Serious 9/25/2008 84 Female 12/23/2008 Other Health Professional
Primary
Concomitant
Vomiting Hospitalization 10/2/2008 69 Female 132 lb 1/19/2009 United Kingdom
Primary
Concomitant
Ventricular Tachycardia Hospitalization 11/21/2008 1/22/2009 Other Health Professional Belgium
Primary
Secondary
Concomitant
Shock Other Serious 11/23/2008 76 Male 185 lb 1/9/2009 Other Health Professional Canada
Primary
Concomitant
Renal Failure Hospitalization 1/9/2006 1/23/2009 Germany
Primary
Concomitant
Vomiting Hospitalization 10/2/2008 69 Female 132 lb 2/5/2009 United Kingdom
Primary
Concomitant
Product Quality Issue Hospitalization 6/12/2008 72 Male 2/10/2009 Lawyer United States
Primary
Concomitant
Metastases To Central Nervous System Death Male 2/18/2009 Consumer United States
Primary
Concomitant
Fall Hospitalization 2/19/2009 80 Male 3/26/2009 Physician France
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 8/4/2008 5/5/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 3/10/2008 15 Female Physician Poland
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1991 Male 188 lb 5/20/2009 Consumer United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 12/15/2005 63 Female 136 lb 5/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 5/30/2009 Physician United States
Primary
Concomitant
Renal Impairment Hospitalization 4/4/2006 57 6/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 8/4/2008 56 6/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 7/10/2009 Physician United States
Primary
Concomitant
Death Death 1/1/2009 Male 7/14/2009 Pharmacist United States
Primary
Concomitant
Pulmonary Hypertension Life Threatening 2/1/2009 Female 7/28/2009 Physician Canada
Primary
Concomitant
Pulmonary Oedema Other Serious 6/16/2008 Female 8/27/2009 Physician Canada
Primary
Concomitant
Hyperaesthesia Other Serious 62 Male 9/2/2009 Other Health Professional Bulgaria
Primary
Secondary
Concomitant
Central Line Infection Hospitalization 8/12/2009 Male 9/4/2009 Physician United Kingdom
Primary
Concomitant
Central Line Infection Hospitalization 8/12/2009 Male 9/28/2009 Physician United Kingdom
Primary
Concomitant
Night Sweats 1/1/2007 60 Female 10/2/2009 Consumer United States
Primary
Concomitant
Pulmonary Hypertension Life Threatening 2/1/2009 Female 10/20/2009 Physician Canada
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 10/23/2009 Physician United States
Primary
Concomitant
Tumour Flare Hospitalization 8/6/2009 Female 127 lb 11/6/2009 Canada
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/9/2009 Female 157 lb 11/23/2009 Physician Australia
Primary
Secondary
Concomitant
Ataxia Hospitalization 3/31/2009 Male 11/27/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 11/9/2009 Female 157 lb 12/2/2009 Physician Australia
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 9/18/2009 Female 154 lb 12/8/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 9/7/2009 55 Female 12/1/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/11/2009 Female 157 lb 12/14/2009 Physician Australia
Primary
Secondary
Concomitant
Splenomegaly Other Serious 6/1/2009 55 Male 12/15/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 11/11/2009 Female 157 lb 12/18/2009 Physician Australia
Primary
Secondary
Concomitant
Neck Pain Hospitalization 3/31/2009 Male 12/30/2009 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 3/16/2006 56 Female 88 lb 12/31/2009 Physician Korea, Republic Of
Primary
Concomitant
Vomiting Hospitalization 11/11/2009 Female 157 lb 1/4/2010 Physician Australia
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 1/12/2010 Physician United States
Primary
Concomitant
Pulmonary Embolism Death 6/1/2009 64 Female 12/24/2009 Other Health Professional Germany
Primary
Concomitant
Urinary Tract Infection Hospitalization 6/12/2008 72 Male 1/26/2010 Lawyer United States
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 2/5/2010 Physician United States
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 2/11/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Death 11/6/2009 Female 163 lb 2/12/2010 United Kingdom
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 2/18/2010 Physician United States
Primary
Concomitant
Urinary Incontinence Other Serious 1/1/2004 Male 174 lb 2/19/2010 United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 2/26/2010 Physician United States
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 3/2/2010 Physician United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 Male 3/4/2010 Lawyer United States
Primary
Concomitant
Vomiting Life Threatening 12/14/2007 69 Male 3/4/2010 Lawyer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 6/12/2008 72 Male 175 lb 3/3/2010 Lawyer United States
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 3/11/2010 Physician United States
Primary
Concomitant
Platelet Count Decreased Other Serious 1/24/2010 Male 3/12/2010 Pharmacist United Kingdom
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 3/18/2010 Physician United States
Primary
Concomitant
Wheelchair User Other Serious 1/1/2004 Male 174 lb 3/22/2010 United States
Primary
Secondary
Concomitant
Pharyngeal Hypoaesthesia 58 Female 3/2/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 3/12/2010 Female 124 lb 3/25/2010 Consumer United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 6/12/2008 72 Male 175 lb 3/25/2010 Lawyer United States
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 3/30/2010 Physician United States
Primary
Concomitant
Non-small Cell Lung Cancer Stage Iv Death 3/19/2010 52 Female 101 lb 3/31/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wheelchair User Other Serious 1/1/2004 57 Male 174 lb 4/6/2010 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/12/2010 46 Female 124 lb 4/8/2010 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 1/24/2010 56 Male 4/20/2010 Pharmacist United Kingdom
Primary
Concomitant
Platelet Count Decreased Other Serious 1/24/2010 56 Male 4/21/2010 Pharmacist United Kingdom
Primary
Concomitant

Drug Data