Lactulose combined with Mirtazapine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 8/24/2004 65 9/12/2005 Physician United States
Primary
Concomitant
Muscle Rigidity Hospitalization 12/11/2005 Male 2/22/2006 Pharmacist United States
Primary
Concomitant
Sudden Death Death 12/15/2005 66 Female 3/3/2006 United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Other Serious 12/3/2005 78 Female 110 lb 3/24/2006 Other Health Professional Belgium
Primary
Concomitant
Transient Ischaemic Attack Other Serious 12/3/2005 78 Female 110 lb 3/27/2006 Other Health Professional Belgium
Primary
Concomitant
Hepatitis 6/28/2005 72 Male 3/30/2006 Canada
Primary
Concomitant
Leukopenia Life Threatening 2/18/2006 18 Female 65 lb 5/31/2006 Physician Austria
Primary
Concomitant
Urinary Tract Infection Pseudomonal Other Serious 2/18/2006 18 Female 65 lb 6/15/2006 Physician Austria
Primary
Concomitant
Hepatitis Acute Hospitalization 6/28/2005 72 Male 6/22/2006 Canada
Primary
Concomitant
Leukopenia Other Serious 5/12/2006 62 Female 185 lb 6/29/2006 Physician Germany
Primary
Secondary
Concomitant
Leukopenia Other Serious 5/12/2006 62 Female 185 lb 7/13/2006 Physician Germany
Primary
Secondary
Concomitant
Urinary Tract Disorder Hospitalization 10/1/2005 56 Female 135 lb 7/31/2006 Physician United States
Primary
Concomitant
Duodenal Ulcer Hospitalization 80 Female 8/23/2006 United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 8/11/2006 Male 174 lb 9/7/2006 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 8/11/2006 Male 174 lb 9/29/2006 Physician Germany
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 12/3/2005 78 Female 110 lb 10/18/2006 Other Health Professional Belgium
Primary
Concomitant
Serotonin Syndrome Disability 3/4/2001 63 Male 2/22/2007 Switzerland
Primary
Secondary
Concomitant
Rash Erythematous Other Serious 74 Female 3/9/2007 Physician Ireland
Primary
Concomitant
Vision Blurred Other Serious 77 Male 4/2/2007 Physician Sweden
Primary
Concomitant
Vision Blurred Other Serious 77 Male 6/1/2007 Physician Sweden
Primary
Concomitant
Tremor Hospitalization 6/3/2007 Female 114 lb 6/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Hospitalization 6/3/2007 59 Female 115 lb 6/8/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Erythematous Other Serious 1/31/2007 74 Female 7/18/2007 Physician Ireland
Primary
Concomitant
Toxic Shock Syndrome Death 10/28/2004 84 Male 8/2/2007 Physician Japan
Primary
Concomitant
Portal Hypertension Hospitalization 10/1/2005 56 Female 135 lb 9/18/2007 Physician United States
Primary
Concomitant
Azotaemia Life Threatening 8/1/2007 Male 10/25/2007 Denmark
Primary
Concomitant
Syncope Vasovagal Hospitalization 10/12/2007 Male 11/8/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Underweight Hospitalization 19 Female 11/7/2007 United Kingdom
Primary
Concomitant
General Physical Health Deterioration Life Threatening 11/6/2006 82 11/14/2007 Physician Germany
Primary
Concomitant
Interacting
General Physical Health Deterioration Life Threatening 11/6/2006 82 11/16/2007 Physician Germany
Primary
Concomitant
Neutropenia Hospitalization 5/7/2007 21 Female 11/19/2007 Physician Germany
Primary
Secondary
Concomitant
Parkinsonism Other Serious 6/9/2007 64 Male 11/21/2007 Physician Germany
Primary
Concomitant
Interacting
General Physical Health Deterioration Life Threatening 11/6/2006 82 Female 11/15/2007 Germany
Primary
Secondary
Parkinsonism Other Serious 6/9/2007 64 Male 12/27/2007 Physician Germany
Primary
Concomitant
Interacting
Pleurothotonus Other Serious 12/22/2007 Female 106 lb 2/6/2008 Physician Austria
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 9/27/2004 67 Male 2/8/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 9/27/2004 67 Male 2/15/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 12/1/2007 91 Female 2/12/2008 Other Health Professional Australia
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 7/18/2007 Male 141 lb 12/10/2007 Pharmacist United States
Primary
Secondary
Concomitant
Surgery Hospitalization 9/27/2004 29 Male 2/26/2008 Germany
Primary
Secondary
Concomitant
Pleurothotonus Other Serious 12/22/2007 71 Female 106 lb 3/25/2008 Physician Austria
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Death Female 4/16/2008 Ireland
Primary
Concomitant
Leukopenia Other Serious 5/12/2006 62 Female 185 lb 4/29/2008 Physician Germany
Primary
Secondary
Concomitant
Portal Hypertension Hospitalization 10/1/2005 Female 135 lb 6/27/2008 Physician United States
Primary
Concomitant
Vascular Occlusion Hospitalization 6/23/2007 71 Male 7/18/2008 Consumer Germany
Primary
Concomitant
Hypotension Hospitalization 7/22/2008 Female 9/2/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Hypotension Hospitalization 7/22/2008 Female 9/4/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 6/23/2007 71 Male 8/25/2008 Physician Germany
Primary
Concomitant
Septic Shock Other Serious 7/5/2008 Female 10/1/2008 Physician United Kingdom
Primary
Concomitant
Toxic Skin Eruption Hospitalization 2/5/2008 Male 10/16/2008 Consumer Germany
Primary
Secondary
Concomitant
Hypotension Other Serious 3/26/2008 Female 176 lb 10/30/2008 Physician Germany
Primary
Concomitant
Hypotension Life Threatening 3/26/2008 Female 176 lb 12/5/2008 Physician Germany
Primary
Concomitant
Skin Necrosis Hospitalization 5/20/2008 Female 12/9/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process 10/1/2008 Male 138 lb 3/6/2009 Consumer United States
Primary
Concomitant
Hepatic Enzyme Abnormal Hospitalization 2/22/2009 89 Female 3/25/2009 Physician United Kingdom
Primary
Concomitant
Gastrointestinal Tube Insertion Hospitalization 2/11/2009 Female 4/9/2009 Pharmacist United Kingdom
Primary
Concomitant
Oedema Disability 8/6/2001 69 Male 7/7/2009 Other Health Professional Denmark
Primary
Concomitant
Rash Other Serious 7/6/2009 75 Male 139 lb 7/31/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Scleroderma Disability 8/6/2001 69 Male 7/31/2009 Other Health Professional Denmark
Primary
Concomitant
Rash Other Serious 7/6/2009 75 Male 138 lb 8/6/2009 Physician United Kingdom
Primary
Concomitant
Nephrogenic Systemic Fibrosis Disability 1/1/2001 69 Male 8/14/2009 Denmark
Primary
Concomitant
Swelling Face Other Serious 8/13/2009 79 Male 9/11/2009 Germany
Primary
Secondary
Concomitant
No Therapeutic Response Hospitalization 8/13/2009 79 Male 9/14/2009 Physician
Primary
Secondary
Concomitant
Gastrointestinal Tube Insertion Hospitalization 2/11/2009 Female 9/22/2009 Pharmacist United Kingdom
Primary
Concomitant
Gastrointestinal Tube Insertion Hospitalization 2/11/2009 Female 10/12/2009 Pharmacist United Kingdom
Primary
Concomitant
Gastrointestinal Tube Insertion Hospitalization 2/11/2009 Female 10/14/2009 United Kingdom
Primary
Concomitant
Cerebral Infarction Other Serious 6/2/2009 84 10/30/2009 Other Health Professional Sweden
Primary
Concomitant
Death Death 9/25/2009 Male 130 lb 11/3/2009 Pharmacist United Kingdom
Primary
Concomitant
Death Death 9/25/2009 Male 130 lb 11/10/2009 Pharmacist United Kingdom
Primary
Concomitant
Skin Necrosis Hospitalization 5/20/2008 Female 11/18/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Tube Insertion Hospitalization 2/11/2009 Female 11/24/2009 Pharmacist United Kingdom
Primary
Concomitant
Oedema Mouth Hospitalization 8/13/2009 79 Male 11/25/2009 Physician Germany
Primary
Secondary
Concomitant
Portal Hypertension Life Threatening 10/1/2005 Female 135 lb 11/30/2009 Other Health Professional United States
Primary
Concomitant
Pulmonary Embolism Life Threatening 11/7/2009 Female 179 lb 12/11/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pruritus Other Serious 10/1/2009 60 Male 265 lb 12/12/2009 Other Health Professional
Primary
Concomitant
Swelling Face Hospitalization 8/13/2009 79 Male 12/14/2009 Consumer Germany
Primary
Concomitant
White Blood Cell Count Increased Other Serious 7/1/2007 Male 130 lb 12/24/2009 Pharmacist United Kingdom
Primary
Concomitant
Pruritus Other Serious 10/1/2009 60 Male 265 lb 2/25/2010 Other Health Professional
Primary
Concomitant
Hypoglycaemia Other Serious 1/25/2010 89 Female 3/29/2010 Physician Denmark
Primary
Concomitant
Renal Failure Acute Other Serious 1/19/2010 Female 118 lb 3/29/2010 Canada
Primary
Secondary
Concomitant
Patella Fracture Other Serious 1/1/2010 66 Female 3/30/2010 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 1/19/2010 37 Female 118 lb 4/1/2010 Canada
Primary
Secondary
Concomitant
Off Label Use Other Serious Female 4/2/2010 Other Health Professional Germany
Primary
Concomitant
Hypersensitivity Hospitalization 11/4/2009 4/22/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Pulmonary Hypertension Hospitalization 11/4/2009 84 Female 4/26/2010 Pharmacist Germany
Primary
Concomitant
Patella Fracture Other Serious 1/1/2010 66 Female 5/5/2010 Consumer United States
Primary
Concomitant
Swollen Tongue Hospitalization 11/4/2009 5/10/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Wheelchair User Other Serious 1/1/2004 57 Male 174 lb 5/13/2010 United States
Primary
Secondary
Concomitant
Nausea 8/1/2008 64 Female 145 lb 7/22/2010 Consumer United States
Primary
Concomitant
Interacting
White Blood Cell Count Decreased Other Serious 5/1/2010 86 Female 7/23/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Sepsis Life Threatening 5/3/2010 86 Female 7/23/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Sepsis Life Threatening 5/3/2010 86 Female 8/12/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2007 65 Female 216 lb 8/27/2010 Lawyer United States
Primary
Concomitant
Wheelchair User Other Serious 1/1/2004 57 Male 174 lb 9/3/2010 United States
Primary
Secondary
Concomitant
Self Injurious Behaviour Hospitalization 74 Female 9/10/2010 Physician United Kingdom
Primary
Concomitant
Cerebral Infarction Other Serious 6/2/2009 84 Male 9/16/2010 Other Health Professional Sweden
Primary
Concomitant
Wheelchair User Other Serious 1/1/2004 57 Male 174 lb 9/30/2010 United States
Primary
Secondary
Concomitant
Wheelchair User Other Serious 1/1/2004 57 Male 174 lb 10/14/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/7/2005 58 Male 174 lb 10/27/2010 United States
Primary
Secondary
Concomitant
Wound Secretion Disability 10/15/2010 84 Female 121 lb 11/16/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wound Secretion Disability 10/15/2010 11/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cerebral Infarction Other Serious 6/2/2009 84 10/30/2009 Other Health Professional Sweden
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/7/2005 58 Male 174 lb 12/24/2010 United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 8/12/2010 92 Female 176 lb 12/17/2010 Germany
Primary
Secondary
Concomitant
Intentional Overdose Hospitalization Male 2/15/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Intervertebral Disc Degeneration Hospitalization 5/7/2005 58 Male 174 lb 2/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Multiple Drug Overdose Intentional Hospitalization 10/8/2010 24 Male 2/25/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Intentional Overdose Hospitalization 10/8/2010 24 Male 2/28/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Multiple Drug Overdose Intentional Hospitalization Male 2/28/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Multiple Drug Overdose Intentional Other Serious 10/8/2010 24 Male 3/4/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization 10/8/2010 24 Male 3/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Intentional Overdose Hospitalization Male 3/7/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization Male 3/7/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization 24 Male 3/1/2011 Physician Denmark
Primary
Secondary
Concomitant
Bile Duct Cancer Death 70 Male 266 lb 3/17/2011 Other Health Professional United States
Primary
Concomitant
Postoperative Wound Complication Other Serious 2/2/2011 60 Female 3/22/2011 Physician Finland
Primary
Concomitant
Abscess Oral Death 2/2/2011 60 Female 3/25/2011 Physician Finland
Primary
Concomitant
Abscess Oral Death 10/1/2010 60 Female 3/28/2011 Other Health Professional Finland
Primary
Concomitant
Herpes Simplex Serology Positive Other Serious 5/7/2005 58 Male 174 lb 4/5/2011 Lawyer United States
Primary
Secondary
Concomitant
Multiple Myeloma Death 1/13/2011 72 Female 4/22/2011 Pharmacist United States
Primary
Concomitant
Fatigue Disability 1/1/2001 69 Male 4/15/2011 Denmark
Primary
Concomitant
Hyperammonaemia Hospitalization 10/15/2010 75 Female 4/29/2011 Physician Japan
Primary
Concomitant
Pain In Jaw 49 Male 132 lb 5/19/2011 Consumer United States
Primary
Concomitant
Toxoplasma Serology Positive Hospitalization 5/7/2005 58 Male 174 lb 6/29/2011 United States
Primary
Secondary
Concomitant
Syncope Other Serious 1/31/2011 65 Male 7/19/2011 Physician Ireland
Primary
Concomitant
Condition Aggravated Hospitalization 10/15/2010 75 Female 7/11/2011 Physician Japan
Primary
Concomitant
Dyspnoea Other Serious 5/1/2011 86 Female 7/20/2011 Consumer United Kingdom
Primary
Concomitant
Cardiomegaly Disability 8/1/2001 69 Male 7/27/2011 Other Health Professional Denmark
Primary
Concomitant
General Physical Health Deterioration Death 4/24/2011 75 Male 8/12/2011 Physician Austria
Primary
Secondary
Concomitant
Fall Other Serious 7/27/2011 94 Female 8/25/2011 Physician Spain
Primary
Secondary
Concomitant
Musculoskeletal Pain Disability 8/1/2001 69 Male 8/25/2011 Physician Italy
Primary
Secondary
Concomitant
General Physical Health Deterioration Death 4/24/2011 75 Male 9/8/2011 Physician Austria
Primary
Secondary
Concomitant
Colon Cancer Death Female 9/22/2011 Physician Switzerland
Primary
Concomitant
Confusional State Hospitalization 9/14/2011 64 Female 163 lb 9/28/2011 Consumer Australia
Primary
Secondary
Concomitant
Convulsion Other Serious 8/1/2011 35 Female 9/30/2011 Physician Ireland
Primary
Concomitant
Confusional State Hospitalization 9/14/2011 64 Female 163 lb 10/5/2011 Physician Australia
Primary
Secondary
Concomitant
Colon Cancer Death Female 10/28/2011 Physician United Kingdom
Primary
Concomitant
Neutropenia Hospitalization 10/16/2011 68 Female 11/3/2011 Physician Australia
Primary
Secondary
Concomitant
Depression Hospitalization 10/16/2011 68 Female 172 lb 11/14/2011 Physician Australia
Primary
Secondary
Concomitant
Convulsion Other Serious 8/1/2011 35 Female 11/14/2011 Physician Ireland
Primary
Concomitant
Pulmonary Embolism Hospitalization 11/17/2011 52 Female 148 lb 11/28/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Potassium Increased Other Serious 11/5/2011 76 Male 11/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Malaise Death Female 11/30/2011 Other Health Professional United Kingdom
Primary
Concomitant
Heart Rate Increased Death 2/25/2011 88 Female 112 lb 12/1/2011 Physician United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 11/5/2011 76 Male 12/5/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nausea Other Serious Female 12/5/2011 Other Health Professional United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 11/5/2011 76 Male 11/30/2011 Other Health Professional
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 10/25/2011 60 Female 12/8/2011 Spain
Primary
Secondary
Concomitant
Colon Cancer Death Female 12/12/2011 Physician United Kingdom
Primary
Concomitant
Anaemia Hospitalization 11/17/2011 52 Female 148 lb 12/19/2011 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data