Lactulose combined with Metoprolol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 8/24/2004 65 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 11/29/2004 9/12/2005 Physician United States
Primary
Concomitant
Pneumonia Aspiration Other Serious 11/1/2005 Female 132 lb 2/24/2006 Physician Germany
Primary
Concomitant
Platelet Count Decreased Hospitalization 10/10/2005 84 Female 148 lb 1/16/2006 Pharmacist United States
Primary
Concomitant
Muscle Rigidity Hospitalization 12/11/2005 Male 2/22/2006 Pharmacist United States
Primary
Concomitant
Electrocardiogram Qt Corrected Interval Prolonged Other Serious 1/1/2004 47 Male 3/20/2006 Pharmacist United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 11/8/2005 62 Female 92 lb 3/15/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 10/1/2002 49 Male 139 lb 5/9/2006 Lawyer United States
Primary
Concomitant
Tachycardia Hospitalization 4/13/2006 60 Male 157 lb 5/12/2006 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Congestion Other Serious 5/27/2003 69 Male 161 lb 5/12/2006 Lawyer United States
Primary
Concomitant
Agranulocytosis Other Serious 3/23/2006 53 Male 6/2/2006 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 11/8/2005 62 Female 93 lb 9/19/2006 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 11/7/2006 75 Male 12/12/2006 Physician Canada
Primary
Concomitant
Liver Function Test Abnormal Other Serious 70 Male 10/18/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Pancreatic Carcinoma Other Serious 7/15/2002 83 Female 10/24/2007 Other Health Professional Canada
Primary
Concomitant
Cardiac Failure Hospitalization 6/6/2007 Male 181 lb 11/2/2007 Germany
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 9/21/2007 54 Female 10/4/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/16/2007 60 Female 140 lb 12/13/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/16/2007 60 Female 140 lb 1/3/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 1/1/2004 84 Female 143 lb 3/27/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 11/4/2005 Male 6/13/2008 Pharmacist
Primary
Secondary
Concomitant
Hepatitis Hospitalization 87 Female 6/25/2008 Consumer Norway
Primary
Secondary
Concomitant
Fatigue Other Serious 7/14/2008 Female 145 lb 8/7/2008 Consumer United States
Primary
Concomitant
Myositis Hospitalization 10/3/2006 70 Male 9/16/2008 Physician United States
Primary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 10/14/2008 81 Male 132 lb 11/12/2008 Other Health Professional Denmark
Primary
Concomitant
Overdose Hospitalization 7/23/2008 63 Male 190 lb 10/27/2008 Physician United States
Primary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 10/14/2008 81 Male 132 lb 11/21/2008 Other Health Professional Denmark
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1991 Male 188 lb 11/21/2008 United States
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 10/14/2008 81 Male 132 lb 12/12/2008 Other Health Professional Denmark
Primary
Concomitant
Pain Other Serious 1/1/2007 Male 110 lb 12/23/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/30/2008 38 Female 139 lb 3/9/2009 Physician United States
Primary
Secondary
Concomitant
Pancreatic Carcinoma Death 83 Female 4/17/2009 Other Health Professional Canada
Primary
Secondary
Pancreatic Carcinoma Death 4/24/2009 Other Health Professional Canada
Primary
Secondary
Pancreatic Carcinoma Death 83 Female 4/27/2009 Other Health Professional Canada
Primary
Secondary
Pneumonia Hospitalization Female 137 lb 4/27/2009 Consumer United States
Primary
Concomitant
Pancreatic Carcinoma Death 83 Female 4/28/2009 Other Health Professional Canada
Primary
Secondary
Vision Blurred Other Serious 1/1/2009 Male 5/12/2009 Consumer
Primary
Concomitant
Vertigo Other Serious 9/7/2002 61 Female 216 lb 5/15/2009 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1991 Male 188 lb 5/20/2009 Consumer United States
Primary
Secondary
Concomitant
Syncope Hospitalization 2/23/2009 45 Male 5/21/2009 Physician United States
Primary
Concomitant
Dysphonia 5/1/2009 81 Female 6/25/2009 Consumer United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 5/1/2009 Male 154 lb 7/10/2009 Physician Netherlands
Primary
Secondary
Concomitant
Vomiting Death 2/1/2008 91 Male 8/13/2009 Physician United States
Primary
Concomitant
Tachycardia Hospitalization 63 Male 8/5/2009 United States
Primary
Concomitant
Tachycardia Hospitalization 63 Male 178 lb 8/11/2009 United States
Primary
Concomitant
Varices Oesophageal Hospitalization 11/23/2007 67 Male 8/12/2009 Consumer United States
Primary
Concomitant
Respiratory Tract Infection Other Serious 1/1/2008 Female 238 lb 8/19/2009 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 66 Male 8/18/2009 United States
Primary
Concomitant
Respiratory Tract Infection Other Serious 1/1/2008 Female 238 lb 9/11/2009 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 66 Male 9/15/2009 United States
Primary
Concomitant
White Blood Cell Count Decreased Death 3/18/2009 Female 9/23/2009 Pharmacist United States
Primary
Concomitant
Vasculitis Other Serious Male 128 lb 9/25/2009 United States
Primary
Concomitant
Confusional State Required Intervention 11/17/2008 82 Female 134 lb 11/19/2008 Pharmacist United States
Primary
Secondary
Concomitant
Surgery Hospitalization 78 Female 9/17/2009 United States
Primary
Concomitant
Spinal Column Stenosis Hospitalization 9/7/2008 53 Male 9/28/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 9/29/2009 United States
Primary
Concomitant
Vasculitis Other Serious Male 128 lb 10/12/2009 United States
Primary
Concomitant
Large Intestine Perforation Other Serious 8/19/2009 Male 10/15/2009 Physician United States
Primary
Concomitant
Motor Dysfunction Death 6/3/2007 80 Female 10/15/2009 Other Health Professional Germany
Primary
Concomitant
Weight Decreased Hospitalization 66 Male 10/10/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 9/7/2008 53 Male 243 lb 10/9/2009 United States
Primary
Concomitant
Pancreatic Carcinoma Death 83 Female 10/22/2009 Other Health Professional Canada
Primary
Secondary
Surgery Hospitalization 78 Female 10/18/2009 United States
Primary
Concomitant
Pancreatic Carcinoma Death 83 Female 10/28/2009 Other Health Professional Canada
Primary
Secondary
Cerebral Haemorrhage Required Intervention 7/25/2009 75 Female 170 lb 9/21/2009 Pharmacist United States
Primary
Concomitant
Haemoglobin Decreased Life Threatening 9/23/2009 75 Male 209 lb 9/25/2009 Pharmacist United States
Primary
Concomitant
Pancreatic Carcinoma Death 83 10/28/2009 Other Health Professional Canada
Primary
Secondary
Weight Increased Hospitalization 80 Female 10/22/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 66 Male 10/22/2009 Consumer United States
Primary
Concomitant
Pancreatic Carcinoma Death 83 Female 10/29/2009 Consumer Canada
Primary
Secondary
Pancreatic Carcinoma Death 83 Female 10/29/2009 Other Health Professional Canada
Primary
Secondary
Pancreatic Carcinoma Death 83 10/30/2009 Other Health Professional Canada
Primary
Secondary
Unresponsive To Stimuli Hospitalization 78 Female 10/26/2009 United States
Primary
Concomitant
Influenza Death 11/5/2009 69 Female 11/11/2009 Pharmacist Canada
Primary
Concomitant
Weight Decreased Hospitalization 66 Male 11/4/2009 United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 78 Female 11/16/2009 United States
Primary
Concomitant
Pancreatic Carcinoma Other Serious 83 Female 11/25/2009 Consumer Canada
Primary
Secondary
Vasculitis Other Serious Male 128 lb 11/27/2009 United States
Primary
Concomitant
Death Death Female 11/30/2009 Consumer United States
Primary
Concomitant
Death Death Female 12/7/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2009 72 Male 12/10/2009 Consumer Germany
Primary
Secondary
Concomitant
Peritonitis Other Serious 5/5/2009 35 Male 11/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Neutrophil Count Increased Death 11/17/2009 Male 12/14/2009 Consumer New Zealand
Primary
Concomitant
Vomiting 4/1/2009 Female 154 lb 11/19/2009 Consumer United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 78 Female 1/11/2010 United States
Primary
Concomitant
Multiple Myeloma Hospitalization 12/14/2009 Female 1/29/2010 Other Health Professional Canada
Primary
Concomitant
Pancreatic Carcinoma Death 83 Female 3/8/2010 Other Health Professional Canada
Primary
Secondary
Vomiting Hospitalization 2/23/2010 Female 119 lb 3/12/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/12/2010 Female 124 lb 3/25/2010 Consumer United States
Primary
Secondary
Concomitant
Lumbar Vertebral Fracture Hospitalization 4/14/2010 65 Male 185 lb 4/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/12/2010 46 Female 124 lb 4/27/2010 Physician United States
Primary
Secondary
Concomitant
Jaundice Other Serious 2/2/2010 72 Male 187 lb 5/7/2010 Physician United States
Primary
Concomitant
Multiple Myeloma Hospitalization 12/14/2009 59 Female 5/10/2010 Physician Canada
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 78 Female 117 lb 4/26/2010 United States
Primary
Concomitant
Sepsis Life Threatening 12/23/2009 51 Female 5/27/2010 Physician Sweden
Primary
Concomitant
Loss Of Consciousness Hospitalization 12/27/2008 54 Male 216 lb 5/28/2010 Physician Canada
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1991 54 Male 188 lb 6/30/2010 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/1991 54 Male 188 lb 7/15/2010 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 10/1/2007 69 Female 157 lb 7/22/2010 Lawyer United States
Primary
Concomitant
Oesophageal Varices Haemorrhage Death 3/12/2010 52 Male 7/23/2010 Other Health Professional United States
Primary
Concomitant
Stomatitis Life Threatening 1/1/2010 77 Male 201 lb 8/3/2010 Pharmacist Canada
Primary
Secondary
Concomitant
Visual Impairment 2/24/2008 79 Female 85 lb 8/3/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/1991 54 Male 188 lb 8/5/2010 Consumer United States
Primary
Secondary
Concomitant
Pancytopenia Other Serious Male 8/11/2010 Physician United States
Primary
Concomitant
Death Death 9/5/2010 64 Male 10/5/2010 Pharmacist Netherlands
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 46 Male 178 lb 10/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2002 65 Male 188 lb 10/18/2010 Consumer United States
Primary
Secondary
Concomitant
Tremor Other Serious 4/1/2008 72 Female 11/1/2010 Physician Sweden
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 46 Male 179 lb 11/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2002 65 Male 188 lb 11/8/2010 Consumer United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization Male 11/8/2010 Consumer Sweden
Primary
Concomitant
Sepsis Death 9/30/2010 72 Female 11/15/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 46 Male 179 lb 11/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2002 65 Male 188 lb 11/18/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2002 65 Male 188 lb 11/24/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/26/2004 52 Female 168 lb 12/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 29 Female 276 lb 11/17/2010 United States
Primary
Concomitant
Dehydration Hospitalization 1/1/2010 83 Male 11/23/2010 Sweden
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 7/1/2009 75 147 lb 12/16/2010 Physician Germany
Primary
Concomitant
Vomiting Hospitalization 3/12/2010 46 Female 124 lb 12/16/2010 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Other Serious 1/1/2010 12/17/2010 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 7/1/2009 75 147 lb 12/17/2010 Physician Germany
Primary
Concomitant
Skin Necrosis Other Serious 11/12/2010 85 Female 12/6/2010 Pharmacist Canada
Primary
Concomitant
Vomiting Other Serious 29 Female 276 lb 12/15/2010 United States
Primary
Concomitant
Lethargy Other Serious 5/1/1994 60 Male 1/10/2011 United States
Primary
Secondary
Concomitant
Anxiety Hospitalization 9/19/2008 45 Male 1/31/2011 Lawyer United States
Primary
Concomitant
Dysphagia Hospitalization 12/25/2010 82 Female 95 lb 2/7/2011 Other Health Professional Canada
Primary
Concomitant
Cerebral Ischaemia Other Serious 12/18/2006 67 Male 2/14/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Death 12/1/2010 77 Male 134 lb 2/14/2011 Pharmacist Netherlands
Primary
Secondary
Concomitant
Hypoalbuminaemia Other Serious 5/1/1994 60 Male 2/21/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 7/1/2009 75 Female 147 lb 2/24/2011 Physician Germany
Primary
Concomitant
Candidiasis Hospitalization Male 2/11/2011 United States
Primary
Concomitant
Clostridial Infection Other Serious 2/16/2010 62 Male 220 lb 3/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 12/1/2010 77 Male 134 lb 3/8/2011 Pharmacist Netherlands
Primary
Secondary
Concomitant
Scoliosis Disability 9/12/2010 91 Female 3/11/2011 Consumer Canada
Primary
Concomitant
Death Death 12/3/2010 77 Male 134 lb 3/11/2011 Pharmacist Netherlands
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/23/2010 59 Female 276 lb 3/11/2011 Pharmacist United States
Primary
Concomitant
Multiple Myeloma Death 1/28/2011 75 Male 4/26/2011 Pharmacist United States
Primary
Concomitant
Abdominal Discomfort Other Serious 3/23/2011 55 Male 180 lb 4/27/2011 Consumer United States
Primary
Concomitant
Acute Myeloid Leukaemia Death 1/15/2011 68 Female 6/2/2011 Pharmacist United States
Primary
Concomitant
Myelodysplastic Syndrome Transformation Death 1/15/2011 68 Female 6/8/2011 Pharmacist United States
Primary
Concomitant
Metastatic Neoplasm Death 12/1/2003 56 Male 6/8/2011 Other Health Professional New Zealand
Primary
Concomitant
Depressed Level Of Consciousness Other Serious 84 Female 6/14/2011 Consumer Canada
Primary
Secondary
Concomitant
Urinary Bladder Haemorrhage Other Serious 6/24/2011 69 Male 183 lb 8/19/2011 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Other Serious 7/25/2011 67 Male 182 lb 8/28/2011 Physician United States
Primary
Concomitant
Failure To Thrive Other Serious 7/25/2011 67 Male 182 lb 9/2/2011 Physician United States
Primary
Concomitant
Constipation Hospitalization 8/1/2011 79 Male 9/5/2011 Netherlands
Primary
Concomitant
Cerebral Ischaemia Other Serious 12/18/2006 67 Male 9/4/2011 Physician United States
Primary
Secondary
Concomitant
Ascites Hospitalization 6/21/2011 66 Male 9/7/2011 Consumer United States
Primary
Concomitant
Blood Glucose Increased Hospitalization 71 Male 265 lb 9/22/2011 Physician Germany
Primary
Interacting

Drug Data