Kytril combined with Leucovorin Calcium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hypotension Other Serious 4/6/2006 60 Male 220 lb 4/21/2006 Physician Sweden
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/2/2006 Female 169 lb 5/3/2006 United States
Primary
Secondary
Concomitant
Hypotension Other Serious 4/6/2006 60 Male 220 lb 5/2/2006 Physician Sweden
Primary
Secondary
Concomitant
Peritonitis Bacterial Hospitalization 4/14/2006 20 Male 185 lb 5/10/2006 Physician Bulgaria
Primary
Concomitant
Vision Blurred 2/6/2006 56 Male 3/1/2006 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 5/2/2006 Female 169 lb 5/9/2006 Physician United States
Primary
Secondary
Concomitant
Perforated Ulcer Hospitalization 5/18/2006 Female 169 lb 5/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/1/2006 65 Female 5/30/2006 United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 65 Female 169 lb 6/12/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 4/28/2006 Female 169 lb 7/3/2006 Physician United States
Primary
Secondary
Concomitant
Motor Dysfunction Hospitalization 1/1/2006 53 Male 6/28/2006 Pharmacist United States
Primary
Secondary
Concomitant
Drug Clearance Decreased Required Intervention 2/24/2004 17 Male 152 lb 7/12/2006 Pharmacist United States
Primary
Concomitant
Stent Placement Life Threatening 5/1/2006 65 Female 7/19/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 5/1/2006 65 Female 7/20/2006 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Death 5/23/2006 Male 159 lb 8/8/2006 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Death 5/23/2006 Male 159 lb 8/15/2006 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 8/1/2006 47 Female 8/30/2006 Physician United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 9/12/2006 73 Male 179 lb 9/19/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Arrest Death 7/27/2006 Male 130 lb 9/21/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 9/12/2006 73 Male 395 lb 10/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 8/24/2006 62 Female 10/18/2006 Physician Finland
Primary
Concomitant
Influenza Like Illness Hospitalization 6/20/2005 33 Female 10/20/2006 Other Health Professional France
Primary
Secondary
Concomitant
Nausea Hospitalization 10/24/2006 60 Male 203 lb 10/25/2006 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious Male 11/17/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/5/2006 Female 11/30/2006 Physician Japan
Primary
Secondary
Concomitant
Peritonitis Bacterial Hospitalization 20 Male 185 lb 12/1/2006 Physician Bulgaria
Primary
Concomitant
Rash Pustular Disability 6/5/2006 Female 12/27/2006 Physician United States
Primary
Secondary
Concomitant
Cardiomyopathy Other Serious 12/26/2006 Male 1/22/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 10/18/2005 Female 99 lb 2/6/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Respiratory Arrest Death 12/26/2006 75 Male 2/8/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 10/18/2005 Female 99 lb 2/9/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 75 Female 2/14/2007 Physician United States
Primary
Secondary
Concomitant
Metastases To Lung Death 10/2/2006 Male 150 lb 3/2/2007 Physician Japan
Primary
Secondary
Concomitant
Neuropathy Peripheral Disability 6/1/2006 43 Female 143 lb 3/23/2007 Physician United States
Primary
Concomitant
Vomiting Hospitalization 75 Female 3/30/2007 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/30/2005 48 Male 4/2/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Palpitations Other Serious 7/12/2006 Male 4/17/2007 Physician
Primary
Concomitant
Metabolic Acidosis Hospitalization 12/6/2006 Male 4/19/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Syncope Hospitalization 10/28/2006 Male 4/20/2007 Physician Canada
Primary
Concomitant
Abdominal Pain Male 237 lb 4/25/2007 Other Health Professional United States
Primary
Concomitant
Staphylococcal Infection Life Threatening 5/8/2006 Female 157 lb 4/26/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Nephrolithiasis Hospitalization 3/29/2007 Female 144 lb 4/30/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 5/8/2006 Female 4/30/2007 Physician United States
Primary
Secondary
Concomitant
Nephrolithiasis Hospitalization 3/29/2007 Female 4/30/2007 Physician United States
Primary
Secondary
Concomitant
Nephrolithiasis Hospitalization 3/29/2007 Female 144 lb 5/3/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Hospitalization 10/28/2006 Male 5/14/2007 Physician Canada
Primary
Concomitant
Rash Disability 6/5/2006 Female 5/21/2007 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 8/31/2006 Male 5/22/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Neuropathy Peripheral 66 Male 205 lb 6/14/2007 United States
Primary
Concomitant
Impetigo Hospitalization 6/4/2007 Male 6/28/2007 Physician Hungary
Primary
Concomitant
Nephrolithiasis Hospitalization 3/29/2007 Female 7/3/2007 Physician United States
Primary
Secondary
Concomitant
Tremor Other Serious 6/25/2007 Female 7/10/2007 Pharmacist Brazil
Primary
Concomitant
Tremor Other Serious 1/31/2007 Female 7/10/2007 Pharmacist Brazil
Primary
Concomitant
Gastric Ulcer Haemorrhage Hospitalization 5/27/2007 Male 106 lb 7/17/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization 6/14/2007 Male 7/17/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Impetigo Hospitalization 6/4/2007 Male 7/18/2007 Physician Hungary
Primary
Concomitant
Hyperammonaemia Life Threatening 10/5/2006 Female 154 lb 7/25/2007 Physician Japan
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization 6/14/2007 Male 8/1/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Tremor Other Serious 6/25/2007 Female 8/2/2007 Pharmacist Brazil
Primary
Concomitant
Urticaria 1/31/2007 Female 8/6/2007 Pharmacist Brazil
Primary
Concomitant
Neuropathy Peripheral Hospitalization 6/14/2007 Male 8/7/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Life Threatening 12/18/2006 20 Male 115 lb 8/2/2007 Physician Japan
Primary
Concomitant
Rash Disability 6/5/2006 Female 8/31/2007 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Impetigo Hospitalization 5/29/2007 Male 8/31/2007 Physician Hungary
Primary
Concomitant
Wheezing Life Threatening 8/21/2007 Male 9/5/2007 Consumer Taiwan, Province Of China
Primary
Concomitant
Tremor Other Serious 5/28/2007 Female 9/7/2007 Pharmacist Brazil
Primary
Concomitant
Rash Disability 6/5/2006 Female 9/10/2007 Physician United States
Primary
Secondary
Concomitant
Tremor Other Serious 5/14/2007 Female 9/12/2007 Pharmacist Brazil
Primary
Concomitant
Metabolic Acidosis Hospitalization 6/17/2007 Female 95 lb 11/2/2007 United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 6/22/2005 Male 165 lb 11/28/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/22/2007 Male 12/13/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 11/5/2007 60 Male 1/22/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Myalgia Other Serious 9/1/2007 39 Female 133 lb 1/25/2008 Consumer United States
Primary
Concomitant
Paraesthesia Other Serious 8/8/2007 Female 2/1/2008 Physician Italy
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization 6/14/2007 Male 2/13/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Skin Discolouration Other Serious Female 126 lb 2/27/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Paraesthesia Other Serious 8/8/2007 Female 2/29/2008 Physician Italy
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 11/5/2007 60 Male 3/26/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Cerebral Haemorrhage Death 3/12/2007 78 Female 2/28/2008 Physician United States
Primary
Concomitant
Cerebral Infarction Hospitalization 11/8/2007 73 Female 2/28/2008 Other Health Professional United States
Primary
Concomitant
Blood Pressure Increased Hospitalization 11/8/2007 Female 2/28/2008 Other Health Professional United States
Primary
Concomitant
Cardio-respiratory Arrest Life Threatening 5/24/2008 Male 185 lb 6/2/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hypoxic Encephalopathy Life Threatening 3/26/2008 Male 119 lb 6/3/2008 Physician Japan
Primary
Secondary
Concomitant
Hypersensitivity Other Serious 4/28/2008 Male 6/5/2008 Physician Canada
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Life Threatening 5/24/2008 Male 185 lb 6/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 9/2/2007 Female 6/20/2008 Physician Japan
Primary
Secondary
Concomitant
Road Traffic Accident Life Threatening 5/24/2008 Male 185 lb 6/23/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 4/30/2008 Female 99 lb 6/24/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Colitis Ischaemic Life Threatening 8/29/2007 74 Male 139 lb 6/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 6/22/2008 Male 141 lb 7/7/2008 United States
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 3/21/2008 Male 139 lb 7/24/2008 Physician Japan
Primary
Secondary
Concomitant
Anaphylactoid Reaction Hospitalization 6/18/2008 Female 7/25/2008 Consumer Japan
Primary
Secondary
Concomitant
Dehydration Hospitalization 5/25/2008 Male 151 lb 7/31/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatic Failure Hospitalization 6/29/2005 Male 165 lb 8/5/2008 Physician United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 5/24/2008 Male 8/8/2008 Physician Italy
Primary
Concomitant
Malignant Neoplasm Progression Death 2/5/2008 Female 8/12/2008 Physician Italy
Primary
Concomitant
Renal Failure Hospitalization 2/4/2008 Female 8/12/2008 Physician Italy
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/14/2007 Female 8/13/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Anaphylactoid Reaction Hospitalization 6/18/2008 Female 8/15/2008 Consumer Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/28/2008 Male 8/19/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 10/29/2007 Female 124 lb 8/20/2008 Physician Japan
Primary
Secondary
Concomitant
Peritonitis Life Threatening 4/10/2007 Female 159 lb 8/21/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Anaphylactic Shock Hospitalization 7/9/2008 Male 138 lb 8/22/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Tumour Haemorrhage Hospitalization 5/26/2008 28 Male 121 lb 8/25/2008 Physician Japan
Primary
Secondary
Concomitant
Bone Marrow Failure Life Threatening 1/4/2008 Female 133 lb 8/27/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Bone Marrow Failure Life Threatening 1/4/2008 Female 133 lb 8/29/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Dehydration Hospitalization 6/22/2008 Male 141 lb 8/29/2008 United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 5/25/2008 Male 151 lb 9/9/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pelvic Abscess Hospitalization 12/20/2005 Male 9/10/2008 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 2/22/2008 Male 139 lb 9/12/2008 Physician Japan
Primary
Secondary
Concomitant
Anaphylactic Shock Hospitalization 7/9/2008 Male 138 lb 9/12/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 7/21/2008 Male 117 lb 9/23/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 6/5/2008 Male 117 lb 9/23/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Peptic Ulcer Disability 1/1/2008 Male 119 lb 10/1/2008 Consumer Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/28/2008 Male 10/1/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pelvic Abscess Hospitalization 12/20/2005 Male 10/8/2008 Physician United States
Primary
Secondary
Concomitant
Multi-organ Failure Hospitalization 8/15/2008 Male 154 lb 10/8/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Metabolic Acidosis Hospitalization 6/17/2007 Female 95 lb 10/14/2008 United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 6/5/2008 Male 117 lb 10/14/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 7/21/2008 Male 117 lb 10/14/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Life Threatening 7/11/2008 Male 10/17/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Life Threatening 7/11/2008 Male 10/22/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Hospitalization 7/30/2007 Male 10/29/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/15/2008 Male 154 lb 10/29/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 7/26/2007 Female 118 lb 10/31/2008 Physician Japan
Primary
Secondary
Concomitant
Multi-organ Failure Hospitalization 8/15/2008 Male 154 lb 11/5/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Peptic Ulcer Disability 1/1/2008 Male 119 lb 11/10/2008 Consumer Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 7/14/2008 Male 11/10/2008 Japan
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 11/19/2007 Male 11/14/2008 Consumer Japan
Primary
Secondary
Concomitant
Septic Shock Life Threatening 10/29/2008 Female 11/26/2008 Other Health Professional France
Primary
Secondary
Concomitant
Sepsis Other Serious 7/11/2008 Male 12/1/2008 Japan
Primary
Secondary
Concomitant
Vomiting Death 9/18/2008 Male 120 lb 12/3/2008 Consumer Japan
Primary
Concomitant
Disease Progression Life Threatening 9/5/2008 Male 12/12/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Varices Oesophageal Other Serious 8/20/2008 Male 12/16/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Hepatitis Other Serious 6/11/2008 Female 135 lb 12/19/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 5/24/2008 Male 192 lb 12/23/2008 Physician Italy
Primary
Concomitant
Sudden Death Death 8/10/2008 Male 12/23/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 11/24/2008 55 Male 123 lb 12/30/2008 Physician Ecuador
Primary
Concomitant
Stomatitis Hospitalization 10/27/2008 Female 128 lb 12/30/2008 Physician Japan
Primary
Secondary
Concomitant
Jejunal Perforation Life Threatening 3/13/2008 Female 105 lb 2/12/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Psychiatric Symptom Hospitalization 12/16/2008 Female 46 lb 3/9/2009 Physician Japan
Primary
Concomitant
Sepsis Other Serious 10/3/2008 60 Female 106 lb 3/12/2009 Physician Japan
Primary
Concomitant
Salivary Hypersecretion 7/8/2008 54 Male 3/25/2009 Consumer United States
Primary
Concomitant
Nausea Hospitalization 3/11/2009 55 Male 148 lb 4/23/2009 Physician Germany
Primary
Secondary
Concomitant
Convulsion Hospitalization 11/2/2008 Female 5/1/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Life Threatening 12/28/2007 Male 165 lb 5/4/2009 Physician Japan
Primary
Secondary
Concomitant
Gastrointestinal Perforation Hospitalization 11/5/2008 Male 5/5/2009 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 3/31/2009 Male 5/6/2009 Consumer Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 4/2/2009 79 Male 5/8/2009 Consumer Japan
Primary
Secondary
Concomitant
Scrotal Oedema Hospitalization 5/26/2008 68 Male 5/5/2009 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data