Klonopin combined with Metformin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Septic Shock Death 71 Female 2/7/2006 Pharmacist United States
Primary
Secondary
Concomitant
Somnolence Other Serious 1/1/2005 43 Male 223 lb 1/20/2006 United States
Primary
Concomitant
Rash 1/21/2005 55 Male 2/28/2006 Consumer United States
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 55 Female 3/13/2006 Consumer United States
Primary
Concomitant
Somnolence Other Serious 4/26/2006 45 Male 5/4/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 3/1/2006 59 Female 5/31/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/29/2006 64 Male 190 lb 6/16/2006 Physician United States
Primary
Secondary
Concomitant
Dry Skin 71 Male 6/6/2006 United States
Primary
Concomitant
Headache 5/13/2005 64 Female 7/21/2006 Consumer United States
Primary
Concomitant
Drug Ineffective 3/1/2006 47 Female 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Suicidal Ideation Death 11/1/2004 57 Female 10/6/2006 Consumer United States
Primary
Secondary
Concomitant
Dermatomyositis Other Serious 9/1/2006 68 Female 120 lb 11/28/2006 Physician United States
Primary
Concomitant
Vision Blurred 9/12/2006 59 Female 182 lb 1/12/2007 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2003 32 Female 237 lb 7/12/2007 Other Health Professional United States
Primary
Concomitant
Pain In Extremity 6/25/2007 Female 249 lb 9/20/2007 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 10/1/2000 Male 10/25/2007 Consumer United States
Primary
Concomitant
Device Occlusion Hospitalization 9/17/2007 61 Female 3/3/2008 Consumer United States
Primary
Concomitant
Drug Ineffective 12/29/2007 60 Male 2/15/2008 United States
Primary
Concomitant
Depression Other Serious 4/1/2008 Female 180 lb 6/20/2008 United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 194 lb 7/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 194 lb 8/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 194 lb 8/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 194 lb 9/9/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased 43 Female 143 lb 1/13/2009 Consumer United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 215 lb 1/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Malaise 9/1/2008 64 Female 176 lb 1/30/2009 Consumer United States
Primary
Concomitant
Neuropathy Peripheral Hospitalization 8/20/2008 73 Male 2/2/2009 Physician United States
Primary
Secondary
Concomitant
Hallucination, Auditory Hospitalization 1/7/2009 59 Female 184 lb 2/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Oedema Hospitalization 12/10/2006 44 Male 239 lb 2/23/2009 Pharmacist United States
Primary
Concomitant
Rash 1/23/2008 39 Female 2/27/2009 Consumer United States
Primary
Concomitant
Rash Pruritic 4/1/2008 57 Female 2/27/2009 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2006 Female 200 lb 3/9/2009 Consumer United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process 2/17/2009 53 Male 5/15/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 45 Male 224 lb 6/25/2009 United States
Primary
Concomitant
Polyneuropathy Other Serious 12/1/2001 50 Female 187 lb 7/1/2009 United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 215 lb 7/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 59 Female 7/19/2009 United States
Primary
Concomitant
Vision Blurred Hospitalization 59 Female 7/22/2009 Lawyer United States
Primary
Concomitant
Pancreatitis Other Serious 6/4/2005 58 Female 202 lb 7/29/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 9/6/2003 53 Female 278 lb 7/29/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/1/2003 30 Female 236 lb 7/28/2009 United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 215 lb 7/31/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vaginal Haemorrhage Other Serious 1/1/2001 44 Female 269 lb 8/5/2009 United States
Primary
Concomitant
Umbilical Hernia Hospitalization 2/1/2004 52 Female 179 lb 8/6/2009 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2004 49 Male 190 lb 8/12/2009 United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 215 lb 8/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 10/13/2008 Female 254 lb 8/18/2009 Physician United States
Primary
Secondary
Concomitant
Headache Female 8/19/2009 Physician United States
Primary
Concomitant
Potentiating Drug Interaction Disability 3/23/2009 43 Female 9/15/2009 Pharmacist United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 6/1/2006 34 Female 213 lb 11/2/2009 United States
Primary
Concomitant
Vomiting Other Serious 1/1/2006 Female 200 lb 12/21/2009 Consumer United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 41 Male 12/30/2009 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 6/1/2006 34 Female 213 lb 1/25/2010 United States
Primary
Concomitant
Urinary Tract Infection 63 Female 209 lb 2/22/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 8/28/2002 71 Female 167 lb 3/12/2010 United States
Primary
Concomitant
Panic Attack Other Serious 12/1/2009 55 Female 240 lb 4/7/2010 Consumer
Primary
Secondary
Memory Impairment Other Serious 12/1/2009 55 Female 240 lb 4/7/2010 Consumer United States
Primary
Secondary
Memory Impairment Other Serious 12/1/2009 55 Female 4/8/2010 Consumer United States
Primary
Secondary
Vomiting Other Serious 1/1/2006 39 Female 200 lb 4/12/2010 Consumer United States
Primary
Secondary
Concomitant
Muscle Spasms Other Serious 12/1/2009 55 Female 4/21/2010 Consumer United States
Primary
Secondary
Myocardial Infarction Other Serious 12/1/2009 55 Female 5/5/2010 Consumer Japan
Primary
Secondary
Restlessness Other Serious 5/17/2010 61 Female 190 lb 6/4/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 5/18/2010 55 Female 181 lb 6/7/2010 Other Health Professional United States
Primary
Concomitant
Memory Impairment Other Serious 12/1/2009 55 Female 6/7/2010 Consumer United States
Primary
Secondary
Muscle Spasms Other Serious 12/1/2009 55 Female 6/1/2010 Consumer United States
Primary
Secondary
Memory Impairment Other Serious 55 Female 6/3/2010 United States
Primary
Secondary
Death Death 1/19/2010 66 Female 6/21/2010 Physician United States
Primary
Concomitant
Spinal Osteoarthritis Other Serious 11/1/2009 57 Female 154 lb 6/22/2010 Physician United States
Primary
Concomitant
Endometrial Disorder Other Serious Female 7/1/2010 Pharmacist United States
Primary
Concomitant
Ventricular Extrasystoles 1/1/1998 37 Female 7/14/2010 United States
Primary
Concomitant
Nervousness 8/1/2007 57 Female 202 lb 7/15/2010 Consumer United States
Primary
Secondary
Concomitant
Inappropriate Schedule Of Drug Administration Hospitalization 1/1/2010 Male 200 lb 7/19/2010 Other Health Professional United States
Primary
Concomitant
Vomiting 2/1/2008 71 Female 185 lb 7/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Premature Menopause Other Serious Female 166 lb 8/6/2010 Pharmacist United States
Primary
Concomitant
Stress 9/12/2009 63 Female 256 lb 8/10/2010 Physician United States
Primary
Concomitant
Psychiatric Symptom Hospitalization 6/1/2010 42 Male 200 lb 8/18/2010 Other Health Professional United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/1/2004 39 Female 290 lb 9/3/2010 United States
Primary
Secondary
Concomitant
Tooth Disorder Other Serious 12/27/2004 41 Male 220 lb 9/3/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2010 63 Male 184 lb 9/3/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization Female 280 lb 9/3/2010 Consumer United States
Primary
Concomitant
Rash Pustular 11/1/2008 66 Female 9/9/2010 Other Health Professional United States
Primary
Concomitant
Nausea 6/18/2009 54 Male 270 lb 9/15/2010 Other Health Professional United States
Primary
Concomitant
Wheezing Other Serious 4/1/2008 56 Female 154 lb 9/16/2010 Physician United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 4/1/2006 40 Male 324 lb 9/20/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 53 Male 266 lb 9/20/2010 United States
Primary
Concomitant
Ventricular Extrasystoles 1/1/1998 37 Female 9/20/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 10/24/2005 43 Male 299 lb 9/20/2010 United States
Primary
Concomitant
Weight Increased 1/31/2003 31 Male 393 lb 9/20/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/6/2004 41 Male 181 lb 9/21/2010 United States
Primary
Concomitant
Wound Other Serious 1/31/2003 31 Male 160 lb 9/21/2010 United States
Primary
Concomitant
Nervousness 9/19/2010 51 Female 200 lb 9/26/2010 Consumer United States
Primary
Concomitant
Nervousness 9/19/2010 51 Female 200 lb 10/4/2010 Consumer United States
Primary
Concomitant
Restlessness Other Serious 5/17/2010 61 Female 201 lb 10/6/2010 Physician United States
Primary
Concomitant
Xerosis Other Serious 1/1/2000 42 Female 296 lb 10/6/2010 United States
Primary
Concomitant
Death Death 8/13/2010 63 Female 10/6/2010 Consumer United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 54 Female 241 lb 10/6/2010 Consumer United States
Primary
Secondary
Concomitant
Tremor Hospitalization 52 Female 10/11/2010 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 60 Male 276 lb 10/12/2010 Consumer United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 37 Female 10/12/2010 Consumer United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 1/1/2004 45 Female 224 lb 10/21/2010 United States
Primary
Concomitant
Pancreatitis Other Serious 1/1/2007 57 Female 211 lb 10/22/2010 Physician United States
Primary
Concomitant
Product Quality Issue 52 Female 10/13/2010 Consumer United States
Primary
Concomitant
Wheezing Other Serious 4/1/2008 56 Female 154 lb 11/1/2010 Physician United States
Primary
Secondary
Concomitant
Tongue Disorder Other Serious 2/1/2010 33 Female 328 lb 11/2/2010 Consumer United States
Primary
Concomitant
Wheezing Other Serious 4/1/2008 56 Female 154 lb 11/3/2010 Physician United States
Primary
Secondary
Concomitant
Enuresis Other Serious 4/1/2008 47 Female 200 lb 11/8/2010 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization Female 280 lb 11/8/2010 Physician United States
Primary
Concomitant
Tendonitis Other Serious Female 11/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 57 Male 250 lb 11/18/2010 Other Health Professional United States
Primary
Concomitant
Spondylitis Other Serious 37 Female 11/18/2010 Consumer United States
Primary
Secondary
Concomitant
Pruritus Generalised 11/12/2010 30 Female 195 lb 11/18/2010 Consumer United States
Primary
Concomitant
Tremor Hospitalization 4/11/2009 54 Male 165 lb 12/7/2010 Consumer United States
Primary
Secondary
Concomitant
Pancreatitis Other Serious 1/1/2007 57 Female 211 lb 12/8/2010 Physician United States
Primary
Concomitant
Tremor Hospitalization 1/1/2009 48 Female 128 lb 12/13/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2006 39 Female 200 lb 12/21/2009 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/8/2010 61 Female 182 lb 12/17/2010 Consumer United States
Primary
Secondary
Concomitant
Tremor Hospitalization 1/1/2009 48 Female 128 lb 12/29/2010 Physician United States
Primary
Concomitant
Agitation Other Serious 10/1/2008 37 Female 1/18/2011 Consumer United States
Primary
Secondary
Concomitant
Dizziness Hospitalization 8/12/2008 36 Female 161 lb 1/28/2011 Physician United States
Primary
Secondary
Concomitant
Hepatic Enzyme Increased 1/1/2007 52 Female 1/29/2011 Consumer United States
Primary
Concomitant
Oropharyngeal Pain 63 Male 1/30/2011 Consumer United States
Primary
Concomitant
Abdominal Pain Upper Hospitalization 7/13/2008 39 Female 190 lb 1/31/2011 Lawyer United States
Primary
Secondary
Concomitant
Chest Pain Hospitalization 11/1/2005 31 Female 219 lb 1/31/2011 Lawyer United States
Primary
Concomitant
Paraesthesia Other Serious Female 2/2/2011 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 1/14/2011 70 Female 2/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Glossodynia Other Serious 2/1/2010 33 Female 328 lb 2/9/2011 Consumer United States
Primary
Concomitant
Abasia Other Serious Male 2/14/2011 Physician United States
Primary
Concomitant
Dysfunctional Uterine Bleeding Other Serious 1/1/2004 45 Female 224 lb 2/18/2011 United States
Primary
Concomitant
Blood Glucose Increased Other Serious 1/1/2010 54 Male 210 lb 2/22/2011 Physician United States
Primary
Secondary
Concomitant
Blood Triglycerides Increased Other Serious 4/1/2008 47 Female 200 lb 2/22/2011 Physician United States
Primary
Concomitant
Blood Urine Present Other Serious 5/1/2008 47 Female 200 lb 2/25/2011 Physician United States
Primary
Concomitant
Rash 54 Female 2/28/2011 Consumer United States
Primary
Concomitant
Blood Glucose Increased Other Serious 4/24/2010 58 Male 180 lb 2/28/2011 Consumer United States
Primary
Concomitant
Gallbladder Disorder Other Serious 9/1/2004 43 Male 237 lb 3/2/2011 United States
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 1/14/2011 70 Female 3/3/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious Male 3/7/2011 Physician United States
Primary
Concomitant
Multiple Allergies Other Serious 11/22/2005 49 Female 150 lb 3/14/2011 Other Health Professional United States
Primary
Concomitant
Back Pain Other Serious 1/1/2010 64 Male 3/14/2011 Consumer United States
Primary
Concomitant
Gallbladder Polyp Other Serious 11/1/2010 45 Male 200 lb 3/15/2011 Physician United States
Primary
Concomitant
Emotional Disorder Other Serious 2/1/2011 49 Female 192 lb 3/16/2011 Consumer United States
Primary
Secondary
Concomitant
Alopecia Other Serious 1/1/2010 48 Female 190 lb 3/17/2011 Consumer United States
Primary
Secondary
Concomitant
Epistaxis Hospitalization 10/28/2009 48 Male 176 lb 3/21/2011 Physician United States
Primary
Secondary
Concomitant
Mental Disorder Hospitalization 11/1/2005 31 Female 219 lb 3/23/2011 Lawyer United States
Primary
Concomitant
Paraplegia Other Serious 4/1/2009 33 Female 180 lb 4/5/2011 Consumer United States
Primary
Secondary
Concomitant
Family Stress Disability 1/1/2008 Female 201 lb 3/29/2011 Lawyer United States
Primary
Concomitant
Tremor 1/5/2011 61 Female 181 lb 4/25/2011 Other Health Professional United States
Primary
Concomitant
Diabetes Mellitus 47 Female 210 lb 4/28/2011 Consumer United States
Primary
Concomitant
Mental Disorder Hospitalization 5/1/2009 51 Female 5/5/2011 Lawyer United States
Primary
Concomitant
Depression Hospitalization 2/1/2009 50 Female 5/5/2011 Lawyer United States
Primary
Concomitant
Dysuria Other Serious 1/1/2008 59 Male 205 lb 5/31/2011 Consumer United States
Primary
Secondary
Concomitant

Drug Data