Keratinamin combined with Nexavar

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Lipase Increased Hospitalization 5/14/2008 66 Male 168 lb 12/23/2008 Physician Japan
Primary
Concomitant
Lipase Increased Hospitalization 5/14/2008 66 Male 168 lb 12/29/2008 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Life Threatening 11/9/2008 62 Male 132 lb 1/16/2009 Physician Japan
Primary
Concomitant
Rash Life Threatening 12/15/2008 78 Female 137 lb 3/3/2009 Physician Japan
Primary
Concomitant
Lipase Increased 5/14/2008 66 Male 168 lb 3/16/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 7/19/2008 53 Male 134 lb 5/26/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 1/31/2009 56 Male 139 lb 8/11/2009 Japan
Primary
Concomitant
Rash Generalised Life Threatening 8/18/2009 54 Male 119 lb 9/24/2009 Physician Japan
Primary
Concomitant
Rash Generalised Life Threatening 8/10/2009 51 Male 123 lb 10/5/2009 Physician Japan
Primary
Concomitant
Diarrhoea Hospitalization 8/10/2009 80 Male 106 lb 10/6/2009 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 7/23/2009 76 Male 141 lb 10/19/2009 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 4/19/2009 77 Male 146 lb 10/19/2009 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 7/23/2009 76 Male 141 lb 10/21/2009 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Hospitalization 8/10/2009 80 Male 106 lb 10/26/2009 Physician Japan
Primary
Concomitant
Rash Life Threatening 8/18/2009 54 Male 119 lb 11/5/2009 Physician Japan
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 10/13/2009 66 Male 157 lb 11/13/2009 Physician Japan
Primary
Concomitant
Rash Death 6/20/2009 73 Male 128 lb 11/20/2009 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 7/15/2009 81 11/20/2009 Physician Japan
Primary
Concomitant
Liver Disorder Other Serious 10/19/2009 65 Male 128 lb 11/20/2009 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Life Threatening 11/4/2008 62 Male 132 lb 11/20/2009 Physician Japan
Primary
Concomitant
Pruritus Other Serious 7/26/2009 48 Male 123 lb 11/23/2009 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 7/31/2009 75 Male 117 lb 11/30/2009 Physician Japan
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 6/30/2009 61 Male 154 lb 12/1/2009 Physician Japan
Primary
Concomitant
Platelet Count Decreased Hospitalization 8/19/2009 80 Female 110 lb 12/2/2009 Physician Japan
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 10/13/2009 66 Male 157 lb 12/4/2009 Physician Japan
Primary
Concomitant
Lipase Increased Hospitalization 5/14/2008 66 Male 168 lb 12/8/2009 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 10/3/2008 78 Female 139 lb 12/10/2009 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Death 10/9/2009 88 Male 130 lb 12/14/2009 Physician Japan
Primary
Concomitant
Skin Papilloma Other Serious 10/2/2009 73 Male 123 lb 12/17/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 1/31/2009 56 Male 139 lb 12/23/2009 Japan
Primary
Concomitant
Rectal Ulcer Life Threatening 7/7/2009 62 Male 150 lb 12/28/2009 Physician Japan
Primary
Concomitant
Pancreatic Enzymes Increased Other Serious 7/23/2009 67 Male 110 lb 12/28/2009 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Death 10/9/2009 88 Male 130 lb 1/6/2010 Physician Japan
Primary
Concomitant
Liver Disorder Other Serious 9/4/2009 66 Male 128 lb 1/15/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Life Threatening 7/30/2009 82 Female 115 lb 1/21/2010 Physician Japan
Primary
Concomitant
Ventricular Extrasystoles Other Serious 9/9/2009 59 Female 134 lb 1/28/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 9/10/2009 63 Male 141 lb 2/1/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/1/2009 63 Female 106 lb 2/2/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Death 10/14/2009 69 Male 143 lb 2/2/2010 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 6/17/2009 62 Male 143 lb 2/8/2010 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 7/23/2009 76 Male 141 lb 2/9/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 7/30/2009 82 Female 115 lb 2/9/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/14/2009 63 Female 106 lb 2/12/2010 Physician Japan
Primary
Concomitant
Transaminases Increased Other Serious 10/19/2009 65 Male 128 lb 2/12/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/1/2008 62 Male 121 lb 2/17/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/1/2008 62 Male 121 lb 2/23/2010 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 7/31/2009 75 Male 117 lb 3/3/2010 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 3/12/2009 75 Male 141 lb 3/4/2010 Physician Japan
Primary
Concomitant
Rash Death 6/1/2009 73 Male 128 lb 3/10/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Death 8/24/2009 75 Male 117 lb 3/10/2010 Physician Japan
Primary
Concomitant
Rash Life Threatening 12/15/2008 78 Female 137 lb 3/10/2010 Physician Japan
Primary
Concomitant
Pneumonia Aspiration Other Serious 11/5/2009 82 Male 112 lb 3/11/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 11/23/2009 56 Female 123 lb 3/15/2010 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 6/17/2009 62 Male 143 lb 3/23/2010 Physician Japan
Primary
Concomitant
Rash Death 6/1/2009 73 Male 128 lb 3/25/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/23/2009 76 Male 141 lb 3/26/2010 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Other Serious 10/9/2009 88 Male 130 lb 4/6/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/14/2009 63 Female 106 lb 4/8/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Death 10/14/2009 69 Male 143 lb 4/15/2010 Physician Japan
Primary
Concomitant
Prothrombin Level Decreased Death 7/29/2009 80 Male 106 lb 4/20/2010 Physician Japan
Primary
Concomitant
Rash Death 6/1/2009 73 Male 128 lb 4/26/2010 Physician Japan
Primary
Secondary
Concomitant
Rash Life Threatening 8/18/2009 54 Male 119 lb 4/29/2010 Physician Japan
Primary
Concomitant
Rash Hospitalization 8/10/2009 51 Male 123 lb 4/29/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/1/2008 62 Male 121 lb 4/29/2010 Physician Japan
Primary
Concomitant
Liver Disorder Other Serious 10/19/2009 65 Male 128 lb 5/7/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 11/24/2009 61 Male 108 lb 5/7/2010 Physician Japan
Primary
Concomitant
Pruritus Other Serious 7/26/2009 48 Male 123 lb 5/11/2010 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 7/23/2009 76 Male 141 lb 5/13/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 4/16/2009 71 Male 121 lb 5/17/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 4/16/2009 71 Male 121 lb 5/18/2010 Physician Japan
Primary
Concomitant
Skin Exfoliation Other Serious 7/7/2009 62 Male 150 lb 5/19/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 4/6/2010 79 Male 6/1/2010 Physician Japan
Primary
Concomitant
Rash Other Serious 8/11/2009 58 Male 170 lb 6/1/2010 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 7/15/2009 81 Male 6/1/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/14/2009 63 Female 106 lb 6/1/2010 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Stage Iii Life Threatening 4/11/2009 83 Female 108 lb 6/1/2010 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Disability 8/28/2009 21 Male 170 lb 6/10/2010 Physician Japan
Primary
Concomitant
Rash Death 6/1/2009 73 Male 128 lb 7/2/2010 Physician Japan
Primary
Secondary
Concomitant
Scrotal Ulcer Death 5/20/2010 64 Male 150 lb 7/7/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Death 2/16/2010 76 Male 137 lb 7/12/2010 Physician Japan
Primary
Concomitant
Pancreatic Enzymes Increased Other Serious 7/23/2009 67 Male 110 lb 7/15/2010 Physician Japan
Primary
Concomitant
Pancreatic Enzymes Increased Other Serious 7/23/2009 67 Male 110 lb 7/16/2010 Physician Japan
Primary
Concomitant
Rash Other Serious 6/30/2009 63 Male 126 lb 7/26/2010 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 7/15/2009 81 Male 7/26/2010 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 5/12/2010 64 Male 150 lb 7/26/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/17/2009 76 Male 146 lb 7/30/2010 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Hospitalization 11/1/2009 57 Male 130 lb 8/10/2010 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 7/15/2009 81 Male 8/18/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Death 2/16/2010 76 Male 137 lb 8/26/2010 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Hospitalization 6/17/2009 62 Male 143 lb 8/27/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 4/6/2010 79 Male 9/9/2010 Physician Japan
Primary
Concomitant
Open Wound Hospitalization 9/9/2010 67 Male 128 lb 9/16/2010 Physician Japan
Primary
Concomitant
Rash Other Serious 6/30/2009 63 Male 126 lb 9/30/2010 Physician Japan
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 9/23/2010 71 Male 10/5/2010 Physician Japan
Primary
Concomitant
Malignant Neoplasm Progression Hospitalization 4/28/2010 66 Male 146 lb 10/5/2010 Physician Japan
Primary
Concomitant
Loss Of Consciousness Hospitalization 9/23/2010 71 Male 10/8/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 5/1/2010 79 Male 126 lb 10/21/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Death 2/16/2010 76 Male 137 lb 10/22/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 9/10/2009 63 Male 141 lb 11/4/2010 Physician Japan
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Disability 8/13/2009 60 Male 126 lb 11/4/2010 Physician Japan
Primary
Concomitant
Hypertension Other Serious 7/26/2010 75 Male 141 lb 11/18/2010 Physician Japan
Primary
Concomitant
Hypertension Hospitalization 7/26/2010 74 Male 141 lb 12/21/2010 Physician Japan
Primary
Concomitant
Rash Hospitalization 3/5/2009 75 Male 141 lb 12/28/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 4/6/2010 79 Male 12/21/2010 Physician Japan
Primary
Concomitant
Dysgeusia Other Serious 10/11/2010 68 Male 130 lb 1/3/2011 Physician Japan
Primary
Concomitant
Hepatic Encephalopathy Hospitalization 11/4/2009 75 Male 157 lb 1/18/2011 Other Health Professional Japan
Primary
Concomitant
Hypertension Hospitalization 7/26/2010 74 Male 141 lb 1/20/2011 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Hospitalization 9/9/2010 67 Male 128 lb 1/28/2011 Physician Japan
Primary
Concomitant
Hepatic Encephalopathy Hospitalization 1/12/2011 83 Male 134 lb 1/28/2011 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Other Serious 12/13/2010 69 Male 130 lb 1/31/2011 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 10/11/2010 68 Male 130 lb 2/10/2011 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/17/2009 76 Male 146 lb 2/18/2011 Physician Japan
Primary
Concomitant
Open Wound Hospitalization 9/9/2010 67 Male 128 lb 2/23/2011 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Death 9/9/2010 67 Male 128 lb 2/24/2011 Physician Japan
Primary
Concomitant
Blood Bilirubin Increased Other Serious 2/9/2011 79 Male 130 lb 3/9/2011 Physician Japan
Primary
Concomitant
Blood Phosphorus Increased Other Serious 2/9/2011 79 Male 130 lb 3/18/2011 Physician Japan
Primary
Concomitant
Pyrexia Death 9/29/2010 66 Male 126 lb 4/4/2011 Physician Japan
Primary
Concomitant
Hepatic Encephalopathy Other Serious 10/28/2010 73 Male 137 lb 4/6/2011 Physician Japan
Primary
Concomitant
Hepatic Encephalopathy Other Serious 9/17/2010 63 Male 4/5/2011 Physician Japan
Primary
Concomitant
Somnolence Other Serious 11/1/2010 63 Male 157 lb 4/12/2011 Physician Japan
Primary
Concomitant
Blood Phosphorus Increased Other Serious 2/24/2011 80 Male 130 lb 4/15/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 10/3/2008 77 Female 139 lb 4/15/2011 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Hospitalization 8/29/2009 63 Female 128 lb 5/21/2011 Physician Japan
Primary
Concomitant
Hepatic Encephalopathy Other Serious 10/28/2010 73 Male 137 lb 5/25/2011 Physician Japan
Primary
Concomitant
Upper Respiratory Tract Inflammation Death 6/17/2009 62 Male 142 lb 5/30/2011 Physician Japan
Primary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 4/6/2010 79 Male 6/3/2011 Physician Japan
Primary
Concomitant
Hypertension Disability 9/6/2010 74 Male 137 lb 6/3/2011 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 7/15/2009 80 Male 6/5/2011 Physician Japan
Primary
Concomitant
Insomnia Other Serious 2/10/2011 80 Male 130 lb 6/29/2011 Physician Japan
Primary
Concomitant
Decreased Appetite Hospitalization 5/31/2010 78 Female 93 lb 7/4/2011 Physician Japan
Primary
Concomitant
General Physical Health Deterioration Hospitalization 9/29/2010 74 Male 7/6/2011 Physician Japan
Primary
Concomitant
Rash Hospitalization 5/31/2010 78 Female 93 lb 7/18/2011 Physician Japan
Primary
Concomitant
Hypertension Death 1/6/2010 62 Male 121 lb 7/25/2011 Physician Japan
Primary
Concomitant
Hyperammonaemia Death 11/6/2010 62 Male 121 lb 7/28/2011 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 8/28/2009 65 Male 128 lb 8/8/2011 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 10/3/2008 77 Female 139 lb 8/8/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 10/3/2008 77 Female 139 lb 8/15/2011 Physician Japan
Primary
Concomitant
Lung Abscess Death 10/3/2008 77 Female 139 lb 8/22/2011 Physician Japan
Primary
Concomitant
Diarrhoea Hospitalization 7/23/2009 75 Male 142 lb 9/14/2011 Physician Japan
Primary
Concomitant
Aspartate Aminotransferase Increased Death 7/23/2009 75 Male 142 lb 11/15/2011 Other Health Professional Japan
Primary
Concomitant
Malaise Other Serious 7/1/2008 62 Male 121 lb 11/18/2011 Physician Japan
Primary
Concomitant
Protein Total Decreased Other Serious 7/1/2008 62 Male 121 lb 11/24/2011 Physician Japan
Primary
Concomitant
Hepatic Failure Hospitalization 9/29/2010 66 Male 126 lb 12/15/2011 Physician Japan
Primary
Concomitant
Decreased Appetite Other Serious 7/28/2010 76 Male 132 lb 12/16/2011 Physician Japan
Primary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 6/28/2011 69 Female 157 lb 1/16/2012 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Other Serious 6/17/2009 62 Male 142 lb 2/3/2012 Physician Japan
Primary
Concomitant
Malaise Other Serious 9/10/2009 62 Male 142 lb 2/6/2012 Physician Japan
Primary
Secondary
Concomitant
Blood Pressure Increased Hospitalization 9/29/2010 74 Male 2/23/2012 Physician Japan
Primary
Concomitant
Jaundice Other Serious 12/13/2010 69 Male 130 lb 3/9/2012 Physician Japan
Primary
Concomitant
Jaundice Other Serious 12/13/2010 69 Male 130 lb 3/16/2012 Physician Japan
Primary
Concomitant

Drug Data