Keppra combined with Topamax

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Nephrolithiasis Other Serious 9/1/2005 39 Female 1/9/2006 United States
Primary
Concomitant
Simple Partial Seizures Other Serious 68 Female 140 lb 1/27/2006 United States
Primary
Secondary
Concomitant
Drug Ineffective 3/1/2005 37 Female 2/8/2006 Consumer United States
Primary
Concomitant
Ulcer Other Serious 1/1/2002 Female 161 lb 2/21/2006 Lawyer United States
Primary
Secondary
Concomitant
Dyspnoea Disability 2/7/2006 46 134 lb 3/10/2006 Other Health Professional United Kingdom
Primary
Interacting
White Blood Cell Count Decreased Other Serious 11/1/2005 10 Female 46 lb 3/13/2006 United States
Primary
Secondary
Concomitant
Dyspnoea Disability 2/7/2006 46 3/16/2006 United Kingdom
Primary
Secondary
Somnolence Other Serious 1/1/1994 32 Female 121 lb 3/29/2006 Physician Germany
Primary
Secondary
Concomitant
Unintended Pregnancy Other Serious 11/25/2005 17 Female 121 lb 4/11/2006 Physician Turkey
Primary
Secondary
Ovarian Cyst Hospitalization 12/30/2001 19 Female 132 lb 4/11/2006 Germany
Primary
Secondary
Mass Other Serious 4/13/2006 Female 23 lb 4/26/2006 Consumer United States
Primary
Concomitant
Psychotic Disorder Hospitalization 5/7/2006 Male 341 lb 5/8/2006 Physician United States
Primary
Concomitant
Convulsion Other Serious 1 Male 21 lb 5/18/2006 Consumer United States
Primary
Concomitant
Oedema Peripheral 2/1/2006 54 Female 132 lb 4/3/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 2/1/2006 54 Female 131 lb 6/5/2006 United States
Primary
Secondary
Concomitant
Ear Infection Other Serious 1 Male 21 lb 6/8/2006 Other Health Professional United States
Primary
Concomitant
Weight Fluctuation Other Serious 1/1/2005 49 Female 6/5/2006 Consumer United States
Primary
Concomitant
Pyrexia Other Serious 3/10/2006 2 Female 26 lb 6/13/2006 Physician United States
Primary
Concomitant
Fall Hospitalization 6/8/2006 46 Male 6/21/2006 Pharmacist United States
Primary
Concomitant
Pyrexia Other Serious 3/10/2006 2 Female 26 lb 7/13/2006 Physician United States
Primary
Concomitant
Blood Glucose Increased 58 Male 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Myoclonus Other Serious 6/1/2006 30 Female 117 lb 7/26/2006 Physician South Africa
Primary
Secondary
Concomitant
Swelling Other Serious 7/24/2006 24 Female 140 lb 8/2/2006 Physician United States
Primary
Concomitant
Drug Interaction Other Serious 7/19/2006 Physician United States
Primary
Secondary
Weight Increased Other Serious 6/14/2006 51 Female 108 lb 7/19/2006 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/1998 69 Male 160 lb 9/8/2006 United States
Primary
Secondary
Urine Output Decreased Life Threatening 8/31/2006 22 Male 139 lb 9/18/2006 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Decreased Other Serious 7/1/2006 Male 295 lb 9/27/2006 Consumer United States
Primary
Concomitant
Foetal Malformation Congenital Anomaly 9/28/2006 Pharmacist United States
Primary
Concomitant
Unevaluable Event Hospitalization 7/22/2006 23 Female 165 lb 10/5/2006 United States
Primary
Concomitant
Acute Febrile Neutrophilic Dermatosis Hospitalization 9/18/2006 50 Female 10/23/2006 Physician Belgium
Primary
Secondary
Concomitant
Tooth Deposit Other Serious 68 Female 151 lb 10/17/2006 United States
Primary
Secondary
Concomitant
Oral Intake Reduced Hospitalization 7/22/2006 22 Female 165 lb 10/13/2006 United States
Primary
Concomitant
Urinary Tract Malformation Congenital Anomaly Male 10/30/2006 Pharmacist United States
Primary
Secondary
Concomitant
Acute Febrile Neutrophilic Dermatosis Hospitalization 9/14/2006 Female 10/31/2006 Physician Belgium
Primary
Secondary
Concomitant
Urine Odour Abnormal Other Serious 2/10/2006 Female 21 lb 8/18/2006 Physician United States
Primary
Concomitant
Convulsion Other Serious 35 Male 11/15/2006 Physician United States
Primary
Concomitant
Acute Febrile Neutrophilic Dermatosis Hospitalization 9/14/2006 Female 11/2/2006 Belgium
Primary
Secondary
Concomitant
Obsessive-compulsive Disorder Other Serious 1/1/2006 27 Female 8/18/2006 United States
Primary
Secondary
Urinary Tract Malformation Congenital Anomaly Male 11/10/2006 United States
Primary
Secondary
Weight Decreased Hospitalization 1/1/2000 27 Male 8/18/2006 United States
Primary
Concomitant
Pyrexia Other Serious 21 Male 145 lb 8/18/2006 Physician United States
Primary
Secondary
Pancreatitis Other Serious 10/13/2005 56 Female 126 lb 8/18/2006 Physician United States
Primary
Concomitant
Swelling Face Hospitalization 9/14/2006 Female 12/8/2006 Physician Belgium
Primary
Secondary
Concomitant
Tremor 8/28/2006 40 Female 12/20/2006 Consumer United States
Primary
Concomitant
Migraine 9/22/2006 40 Female 12/20/2006 Consumer United States
Primary
Concomitant
Status Epilepticus Hospitalization 8/14/2005 6 Female 37 lb 9/27/2006 Physician United States
Primary
Secondary
Concomitant
Headache Other Serious 1/1/2005 46 Female 310 lb 10/4/2006 United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 1/1/2005 46 Female 308 lb 10/4/2006 United States
Primary
Secondary
Concomitant
Urinary Tract Malformation Congenital Anomaly Male 1/15/2007 Pharmacist United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2006 Female 180 lb 2/15/2007 Consumer United States
Primary
Secondary
Concomitant
Dizziness Female 2/28/2007 Consumer United States
Primary
Secondary
Concomitant
Eye Pain Other Serious 1/1/2007 11 Female 2/23/2007 Consumer United States
Primary
Concomitant
Hip Dysplasia Congenital Anomaly Female 7 lb 3/8/2007 Other Health Professional United Kingdom
Primary
Secondary
Sweat Chloride Test Abnormal Other Serious Female 132 lb 3/8/2007 Physician Germany
Primary
Concomitant
Transaminases Increased Hospitalization 2/14/2007 52 Male 176 lb 3/6/2007 Pharmacist United States
Primary
Concomitant
Therapeutic Response Delayed Other Serious 21 Female 180 lb 3/6/2007 United States
Primary
Secondary
Concomitant
Tardive Dyskinesia Required Intervention 40 Female 8/21/2004 Physician United States
Primary
Concomitant
Convulsion Hospitalization 3/13/2007 40 Female 4/9/2007 United States
Primary
Concomitant
Unevaluable Event Other Serious 3/10/2006 2 Female 26 lb 4/9/2007 Physician United States
Primary
Concomitant
Respiratory Distress Other Serious 1/1/2001 46 Male 149 lb 5/7/2007 Physician United States
Primary
Concomitant
Petit Mal Epilepsy Other Serious 5/31/2006 5 Female 51 lb 5/4/2007 Germany
Primary
Concomitant
Grand Mal Convulsion Other Serious 3/1/2007 Female 240 lb 5/17/2007 Consumer United States
Primary
Secondary
Concomitant
Pregnancy Other Serious 2/1/2007 25 Female 5/9/2007 Physician United States
Primary
Concomitant
Pain Other Serious 45 Female 5/14/2007 United States
Primary
Concomitant
Therapeutic Response Delayed Other Serious 21 Female 180 lb 3/6/2007 Consumer United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 21 Female 180 lb 1/19/2007 Physician United States
Primary
Secondary
Concomitant
Suicidal Behaviour Other Serious 1/1/2000 Female 202 lb 5/23/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Cholecystitis Hospitalization 3/15/2007 45 Female 240 lb 5/23/2007 Physician United States
Primary
Concomitant
Leukopenia Other Serious 3/1/2006 Male 265 lb 6/1/2007 Physician Germany
Primary
Secondary
Tinnitus Other Serious 5/1/2007 Female 205 lb 6/21/2007 Consumer United States
Primary
Concomitant
Paranoia Other Serious 5/31/2007 Female 118 lb 6/25/2007 Other Health Professional United States
Primary
Secondary
Suicidal Behaviour Other Serious 1/1/2000 Female 202 lb 6/28/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Paranoia Hospitalization 5/31/2007 13 Female 118 lb 6/21/2007 Physician United States
Primary
Secondary
Nausea 4/27/2007 51 Female 7/6/2007 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 1/24/2003 28 Female 7/9/2007 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 188 lb 7/17/2007 United States
Primary
Secondary
Concomitant
Status Epilepticus Other Serious Female 7/26/2007 Consumer United States
Primary
Secondary
Concomitant
Pitting Oedema 12/1/2006 Female 184 lb 7/26/2007 Physician United States
Primary
Concomitant
Suicidal Ideation Other Serious 4/25/2007 Female 150 lb 8/1/2007 United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Other Serious 8/7/2004 39 Female 158 lb 6/8/2007 Physician United States
Primary
Concomitant
Restless Legs Syndrome Other Serious Female 8/16/2007 Consumer Germany
Primary
Concomitant
Memory Impairment Other Serious 8/8/2007 Consumer United States
Primary
Secondary
Stress Other Serious Female 8/9/2007 United States
Primary
Secondary
Status Epilepticus Other Serious Female 8/22/2007 United States
Primary
Secondary
Concomitant
Drug Hypersensitivity Other Serious 8/9/2007 Female 228 lb 8/28/2007 Consumer United States
Primary
Secondary
Concomitant
Nausea 4/7/2007 46 Female 198 lb 7/11/2007 Consumer United States
Primary
Concomitant
Talipes Congenital Anomaly 6 lb 8/22/2007 United States
Primary
Secondary
Myelopathy Other Serious 44 Male 122 lb 8/20/2007 Pharmacist United States
Primary
Concomitant
Lumbar Puncture Other Serious 8/9/2007 Female 228 lb 8/31/2007 Consumer United States
Primary
Secondary
Concomitant
Talipes Congenital Anomaly 6 lb 8/30/2007 Other Health Professional United States
Primary
Secondary
Lumbar Puncture Other Serious 8/9/2007 Female 228 lb 9/6/2007 United States
Primary
Secondary
Concomitant
Foetal Malformation Other Serious 2/1/2007 Male 9/20/2007 Consumer United States
Primary
Concomitant
Pancytopenia Other Serious 3/1/2007 50 Female 211 lb 9/17/2007 Physician United States
Primary
Concomitant
Visual Acuity Reduced Other Serious Male 159 lb 9/26/2007 Physician Germany
Primary
Concomitant
Renal Failure Hospitalization 7/19/2007 41 Female 92 lb 9/26/2007 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2006 14 Female 125 lb 9/26/2007 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/1/2006 14 Female 125 lb 10/2/2007 Physician United States
Primary
Secondary
Concomitant
Mitochondrial Cytopathy Other Serious 1/1/2007 2 Female 10/10/2007 Consumer United States
Primary
Concomitant
Infusion Related Reaction Hospitalization 7/1/2007 45 Female 10/10/2007 Other Health Professional United States
Primary
Concomitant
Tremor Other Serious 9/28/2007 Female 9/28/2007 Pharmacist United States
Primary
Concomitant
Visual Acuity Reduced Other Serious Male 159 lb 10/18/2007 Physician Germany
Primary
Concomitant
Renal Failure Hospitalization 7/19/2007 41 Female 92 lb 10/16/2007 Consumer United States
Primary
Concomitant
Tongue Dry Other Serious 3/1/2007 69 Male 155 lb 10/26/2007 Consumer United States
Primary
Concomitant
Dyspepsia Other Serious 70 Male 175 lb 10/11/2007 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 8/1/2007 27 Female 10/23/2007 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 8/1/2007 27 Female 10/23/2007 Physician United States
Primary
Concomitant
Tremor Other Serious 3/1/2007 69 Male 155 lb 11/6/2007 Consumer United States
Primary
Concomitant
Traumatic Brain Injury Other Serious 6/1/2006 62 Male 231 lb 11/10/2007 Physician Germany
Primary
Secondary
Concomitant
Encephalopathy Other Serious Male 11/21/2007 Physician United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 11/18/2007 57 Female 119 lb 11/26/2007 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Other Serious 3/28/2007 52 Female 11/27/2007 Switzerland
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Other Serious 11/19/2007 Female 12/5/2007 Consumer United States
Primary
Secondary
Sweat Chloride Test Abnormal Other Serious Female 132 lb 12/17/2007 Physician Germany
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 11/18/2007 35 Female 12/10/2007 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 10/4/2007 40 Female 12/19/2007 Physician Germany
Primary
Concomitant
Somnolence Life Threatening 34 Female 12/27/2007 Consumer Italy
Primary
Secondary
Vomiting Hospitalization 12/3/2007 13 Female 141 lb 12/20/2007 Physician Czech Republic
Primary
Secondary
Somnolence Life Threatening 34 Female 1/17/2008 Physician Italy
Primary
Secondary
Swelling Hospitalization 1/7/2008 37 Female 190 lb 1/22/2008 Other Health Professional United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2006 Female 175 lb 2/8/2008 Consumer United States
Primary
Secondary
Concomitant
Speech Disorder Other Serious 11/18/2007 35 Female 162 lb 2/1/2008 Physician United States
Primary
Concomitant
Psychotic Disorder Hospitalization 18 Male 2/8/2008 Germany
Primary
Secondary
Suicide Attempt Life Threatening 2/13/2008 23 Female 131 lb 2/22/2008 United States
Primary
Secondary
Lumbar Puncture Other Serious 8/9/2007 Female 227 lb 3/6/2008 United States
Primary
Secondary
Concomitant
Vomiting 52 Female 3/7/2008 Consumer United States
Primary
Concomitant
Hallucination Other Serious 45 Female 3/7/2008 Consumer Australia
Primary
Concomitant
Hyperammonaemia Other Serious 1/1/2008 3/13/2008 Physician Taiwan, Province Of China
Primary
Concomitant
Thrombosis Hospitalization 10/7/2007 44 Female 3/17/2008 United States
Primary
Concomitant
Renal Cyst Other Serious Female 3/14/2008 Germany
Primary
Concomitant
Paranoia Other Serious Female 187 lb 3/25/2008 Physician Australia
Primary
Concomitant
Tooth Loss Other Serious Male 160 lb 3/27/2008 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/1/2006 8 Male 64 lb 3/26/2008 Physician Germany
Primary
Concomitant
Weight Decreased Other Serious 1/8/2008 69 Male 181 lb 4/7/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting 10/10/2005 65 Female 247 lb 10/30/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Dysstasia Hospitalization 3/24/2008 2 Female 24 lb 4/10/2008 Consumer United States
Primary
Concomitant
Tremor Other Serious 1/19/2007 Male 4/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Lumbar Puncture Other Serious 1/1/2007 Female 227 lb 4/18/2008 United States
Primary
Secondary
Concomitant
Death Other Serious 4/6/2008 Male 4/21/2008 Physician United States
Primary
Concomitant
Suicidal Ideation Other Serious Male 160 lb 4/21/2008 Lawyer United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 1/20/2007 Male 5/1/2008 Physician Ireland
Primary
Secondary
Concomitant
Suicide Attempt Life Threatening 3/23/2007 Female 152 lb 5/23/2008 Physician Germany
Primary
Secondary
Renal Cyst Other Serious Female 5/15/2008 Physician Germany
Primary
Concomitant
Paranoia Other Serious Female 187 lb 5/30/2008 Physician Australia
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 Female 162 lb 6/2/2008 Consumer United States
Primary
Secondary
Concomitant
Tardive Dyskinesia Hospitalization 12 Male 5/21/2008 Other Health Professional United States
Primary
Concomitant
Sweat Test Abnormal Other Serious 1/1/2007 Female 132 lb 6/4/2008 Physician Germany
Primary
Concomitant
Oedema Peripheral Other Serious 4/1/2008 52 Female 123 lb 6/6/2008 Belgium
Primary
Concomitant
Urinary Tract Infection Other Serious 4/29/2007 Male 143 lb 6/20/2008 United States
Primary
Secondary
Concomitant
Varicella Hospitalization 5/10/2008 4 Female 6/27/2008 China
Primary
Concomitant

Drug Data