Keppra combined with Lacosamide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hepatic Cancer Metastatic Death 12/1/2008 Female 1/23/2009 Physician Germany
Primary
Secondary
Suicide Attempt Hospitalization 11/17/2007 22 Female 12/11/2008 United States
Primary
Secondary
Concomitant
Pregnancy On Contraceptive Other Serious Female 292 lb 3/5/2009 Germany
Primary
Concomitant
Tachycardia Hospitalization 1/1/2009 Female 176 lb 6/1/2009 Germany
Primary
Secondary
Concomitant
Hyponatraemia Death 63 Female 7/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Haemorrhage Other Serious 11/1/2008 Female 163 lb 7/20/2009 Consumer United States
Primary
Concomitant
Hyperventilation Other Serious 7/15/2009 44 Female 7/29/2009 Consumer Austria
Primary
Concomitant
Pulmonary Oedema Neonatal Hospitalization 6/22/2009 Female 7 lb 8/12/2009 Physician United States
Primary
Secondary
Concomitant
Convulsion 6/29/2009 Male 225 lb 8/21/2009 Consumer United States
Primary
Secondary
Concomitant
Rash Pruritic 49 Male 8/21/2009 Physician United States
Primary
Concomitant
Urinary Incontinence 7/8/2009 Female 121 lb 8/21/2009 Consumer United States
Primary
Secondary
Concomitant
Petechiae Other Serious 7/9/2009 Female 163 lb 8/21/2009 Consumer United States
Primary
Secondary
Concomitant
Rash Female 153 lb 8/21/2009 Consumer United States
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization Male 9/4/2009 Germany
Primary
Secondary
Rash Hospitalization 8/16/2009 Female 9/4/2009 United States
Primary
Secondary
Psychotic Disorder Hospitalization 6/27/2009 Female 83 lb 9/2/2009 Consumer United States
Primary
Secondary
Concomitant
Depression Hospitalization Male 224 lb 9/24/2009 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 65 Female 9/24/2009 Physician United States
Primary
Concomitant
Petit Mal Epilepsy Other Serious Female 137 lb 10/1/2009 Consumer United States
Primary
Secondary
Concomitant
Drug Toxicity Other Serious 12 Male 9/25/2009 Physician United States
Primary
Secondary
Concomitant
Fibrocystic Breast Disease Other Serious 1/22/2009 Female 108 lb 10/28/2009 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 50 Female 11/3/2009 Physician United States
Primary
Concomitant
Syncope 6/16/2009 Male 11/11/2009 Physician United States
Primary
Concomitant
Swollen Tongue Other Serious Female 154 lb 11/16/2009 Pharmacist United States
Primary
Secondary
Concomitant
Ureteric Obstruction Other Serious 3/6/2009 Female 12/1/2009 United States
Primary
Concomitant
Depression Hospitalization 8/7/2009 Male 223989 lb 12/1/2009 Consumer United States
Primary
Concomitant
Yellow Skin Other Serious Male 162 lb 12/10/2009 Consumer United States
Primary
Secondary
Concomitant
Urinary Incontinence Female 118 lb 11/19/2009 Consumer United States
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy 6/15/2009 37 Female 11/19/2009 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 11/19/2009 Physician United States
Primary
Concomitant
Suicide Attempt Life Threatening 8/1/2009 Male 122 lb 11/19/2009 United States
Primary
Secondary
Concomitant
Vomiting 4/1/2009 Female 154 lb 11/19/2009 Consumer United States
Primary
Secondary
Concomitant
Pain Female 11/19/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Speech Disorder Male 11/19/2009 Physician United States
Primary
Secondary
Rash Pruritic 11/19/2009 United States
Primary
Secondary
Concomitant
Myoclonus Male 11/19/2009 Physician United States
Primary
Secondary
Concomitant
Off Label Use 8 Male 11/19/2009 United States
Primary
Secondary
Orgasmic Sensation Decreased 21 Female 11/19/2009 Physician United States
Primary
Secondary
Alopecia 1/1/2006 Female 185 lb 11/19/2009 Consumer United States
Primary
Secondary
Concomitant
Drug Level Decreased 9/1/2009 21 Male 11/19/2009 Pharmacist United States
Primary
Secondary
Yellow Skin Other Serious Male 162 lb 12/11/2009 Consumer United States
Primary
Secondary
Concomitant
Cholelithiasis Other Serious 8/1/2009 Male 194 lb 12/11/2009 Physician United States
Primary
Concomitant
Status Epilepticus Hospitalization Male 12/22/2009 Physician United States
Primary
Secondary
Concomitant
Postictal State Hospitalization 10/1/2009 Female 150 lb 12/29/2009 Physician Germany
Primary
Concomitant
Psychomotor Hyperactivity Hospitalization 12/1/2008 21 Male 1/12/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
No Therapeutic Response 8/1/2009 Male 194 lb 1/5/2010 Physician United States
Primary
Concomitant
Tachycardia Other Serious Female 205 lb 1/7/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 9/20/2007 Male 183 lb 1/19/2010 Germany
Primary
Concomitant
Weight Decreased Other Serious Male 1/19/2010 Germany
Primary
Concomitant
Tension Other Serious 8/27/2008 Male 159 lb 1/22/2010 Physician Germany
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/13/2010 Male 212 lb 1/26/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 4/1/2009 Female 154 lb 1/26/2010 United States
Primary
Secondary
Concomitant
Convulsion Hospitalization Female 79 lb 1/25/2010 Consumer United States
Primary
Secondary
Concomitant
Fatigue Other Serious 1/1/2009 Female 118 lb 1/26/2010 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 50 Female 1/26/2010 Physician United States
Primary
Secondary
Concomitant
Treatment Failure Other Serious 8/27/2008 72 Male 159 lb 2/5/2010 Physician Germany
Primary
Concomitant
Paralysis Other Serious Female 2/3/2010 Consumer United States
Primary
Secondary
Status Epilepticus Hospitalization 10/1/2009 Female 150 lb 2/22/2010 Other Health Professional Germany
Primary
Concomitant
Oedema Peripheral Other Serious Female 118 lb 3/12/2010 Consumer United States
Primary
Secondary
Suicidal Ideation Other Serious 2/11/2010 Physician United States
Primary
Secondary
Concomitant
Upper Limb Fracture Other Serious 6/1/2007 Female 140 lb 2/11/2010 Consumer United States
Primary
Secondary
Concomitant
Fatigue Life Threatening 1/1/2009 Female 118 lb 2/11/2010 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 10/1/2009 71 Female 143 lb 4/19/2010 Consumer United States
Primary
Secondary
Concomitant
Medication Error Other Serious Male 153 lb 4/23/2010 Consumer United States
Primary
Secondary
Concomitant
Anticonvulsant Drug Level Above Therapeutic Hospitalization 4/1/2010 45 Female 132 lb 4/30/2010 Other Health Professional United States
Primary
Concomitant
Petit Mal Epilepsy Other Serious Male 153 lb 5/5/2010 Consumer United States
Primary
Secondary
Concomitant
Tremor Other Serious 4/26/2010 56 Female 170 lb 5/6/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious Female 206 lb 5/4/2010 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2009 12 Male 5/14/2010 Physician United States
Primary
Secondary
Concomitant
Status Epilepticus Other Serious 5/10/2010 44 Female 196 lb 5/18/2010 Physician United States
Primary
Concomitant
Convulsion Other Serious 5/25/2010 44 Female 196 lb 6/4/2010 Other Health Professional United States
Primary
Concomitant
Urticaria Other Serious 1/1/2008 16 Male 224 lb 6/8/2010 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 10/1/2009 71 Female 143 lb 6/14/2010 United States
Primary
Secondary
Concomitant
Ammonia Increased Hospitalization 5/10/2010 42 Male 185 lb 6/17/2010 Other Health Professional United States
Primary
Concomitant
Tremor Other Serious Male 6/24/2010 Physician Germany
Primary
Secondary
Concomitant
Tachycardia Other Serious Female 205 lb 6/23/2010 Consumer United States
Primary
Secondary
Concomitant
Swollen Tongue Other Serious Female 154 lb 6/25/2010 Pharmacist United States
Primary
Secondary
Concomitant
Blindness Other Serious 6/29/2010 Physician United States
Primary
Secondary
Suicidal Ideation Other Serious 5/28/2010 Male 6/29/2010 Other Health Professional United States
Primary
Secondary
Status Epilepticus Hospitalization Male 6/25/2010 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral Female 5/20/2010 Physician United States
Primary
Secondary
Concomitant
Pruritus Female 5/20/2010 Consumer United States
Primary
Concomitant
Skin Exfoliation 3/1/2010 64 Female 114 lb 5/20/2010 United States
Primary
Concomitant
Nausea 3/25/2010 44 Female 182 lb 5/20/2010 Consumer United States
Primary
Concomitant
Pruritus Genital 2/1/2010 50 Female 212 lb 5/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Headache 2/15/2010 52 Female 190 lb 5/20/2010 United States
Primary
Secondary
Concomitant
Paranoia Female 5/20/2010 Physician United States
Primary
Secondary
Concomitant
Agitation 5/20/2010 Physician United States
Primary
Secondary
Drop Attacks Male 5/20/2010 Physician United States
Primary
Secondary
Concomitant
Hemiparesis Other Serious 5/25/2010 44 Female 196 lb 7/20/2010 Other Health Professional United States
Primary
Concomitant
Suicidal Ideation Other Serious 5/28/2010 40 Male 7/22/2010 Other Health Professional United States
Primary
Secondary
Pulmonary Oedema Neonatal Hospitalization Female 7 lb 7/26/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization Male 189 lb 7/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 7/1/2009 25 Female 140 lb 7/27/2010 Physician United States
Primary
Concomitant
Sudden Death Death Male 7/30/2010 Other Health Professional United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization Female 78 lb 8/4/2010 Physician United States
Primary
Secondary
Concomitant
Status Epilepticus Other Serious 5/22/2010 44 Female 196 lb 8/5/2010 Other Health Professional United States
Primary
Concomitant
Dizziness 7/1/2010 52 Female 150 lb 8/16/2010 Consumer United States
Primary
Secondary
Concomitant
Atrioventricular Block Complete Other Serious 8/16/2010 Physician United States
Primary
Secondary
Pain Other Serious 47 Female 8/18/2010 United States
Primary
Secondary
Convulsion 8/18/2009 29 Male 198 lb 8/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 30 Male 130 lb 8/25/2010 Consumer United States
Primary
Concomitant
Grand Mal Convulsion Other Serious 5/22/2010 44 Female 196 lb 8/30/2010 Physician United States
Primary
Concomitant
Dialysis 9/2/2010 United States
Primary
Secondary
Arrhythmia Death Male 9/2/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 29 Female 8/31/2010 Physician United States
Primary
Secondary
Grand Mal Convulsion Other Serious 5/22/2010 44 Female 196 lb 9/7/2010 Other Health Professional United States
Primary
Concomitant
Lip Swelling 22 Female 8/19/2010 Physician United States
Primary
Secondary
Concomitant
Mania 4/8/2010 15 Male 111 lb 8/19/2010 Other Health Professional United States
Primary
Concomitant
Somnolence 6/7/2010 55 Male 185 lb 8/19/2010 United States
Primary
Concomitant
Hyperhidrosis Male 335 lb 8/19/2010 Consumer United States
Primary
Secondary
Concomitant
Pain In Extremity 6/9/2010 48 Male 134 lb 8/19/2010 United States
Primary
Concomitant
Mood Altered 12/1/2009 38 Female 127 lb 8/19/2010 Consumer United States
Primary
Concomitant
Rib Fracture 73 Male 8/19/2010 Physician United States
Primary
Concomitant
Swollen Tongue Other Serious Female 154 lb 8/19/2010 Pharmacist United States
Primary
Secondary
Concomitant
Inappropriate Schedule Of Drug Administration Life Threatening Female 118 lb 8/19/2010 Consumer United States
Primary
Secondary
Concomitant
Suicidal Ideation Life Threatening 7/12/2009 22 Female 8/19/2010 Physician United States
Primary
Concomitant
Status Epilepticus Hospitalization 27 Male 8/2/2010 Physician United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious Male 8/19/2010 Pharmacist United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious Female 8/19/2010 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious Female 118 lb 9/16/2010 Consumer United States
Primary
Secondary
Skin Lesion Life Threatening Female 118 lb 9/14/2010 Consumer United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 30 Male 130 lb 9/15/2010 Consumer United States
Primary
Concomitant
Syncope 1/1/2009 64 Female 112 lb 9/17/2010 Consumer United States
Primary
Secondary
Concomitant
Arrhythmia Death Male 9/20/2010 Other Health Professional United States
Primary
Concomitant
Therapy Regimen Changed Other Serious 9/7/2010 47 Female 118 lb 9/21/2010 Consumer United States
Primary
Secondary
Malaise Hospitalization 9/11/2010 45 Female 9/22/2010 Other Health Professional United States
Primary
Secondary
Suicide Attempt Other Serious 30 Male 130 lb 9/23/2010 Consumer United States
Primary
Concomitant
Convulsion 1/1/2009 38 Male 223 lb 9/29/2010 United States
Primary
Secondary
Fall Other Serious 1/1/2010 42 Male 185 lb 9/30/2010 Physician United States
Primary
Concomitant
Vision Blurred 1/1/2009 64 Female 112 lb 10/1/2010 Consumer United States
Primary
Secondary
Concomitant
Hypersensitivity Other Serious 55 Female 10/5/2010 Physician United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 4/21/2010 54 Male 218 lb 10/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hospitalisation Hospitalization 21 Male 10/6/2010 Consumer United States
Primary
Secondary
Product Formulation Issue Other Serious Female 150 lb 10/5/2010 Consumer United States
Primary
Secondary
Concomitant
Product Formulation Issue Other Serious Female 150 lb 10/5/2010 Consumer United States
Primary
Secondary
Concomitant
Status Epilepticus Hospitalization 3/1/2010 24 Male 10/18/2010 Consumer United States
Primary
Secondary
Stomatitis Hospitalization 4/21/2010 54 Male 218 lb 10/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Other Serious Female 150 lb 10/8/2010 Physician United States
Primary
Secondary
Concomitant
Road Traffic Accident Hospitalization 9/27/2009 47 Female 219 lb 10/11/2010 Other Health Professional United States
Primary
Concomitant
Suicide Attempt Other Serious 30 Male 130 lb 10/12/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/27/2009 5 43 lb 10/13/2010 Physician Greece
Primary
Concomitant
Stomatitis Hospitalization 4/21/2010 54 Male 218 lb 10/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 10/14/2010 63 Female 187 lb 10/26/2010 Physician Spain
Primary
Secondary
Concomitant
Status Epilepticus Hospitalization 3/1/2010 23 Male 210 lb 10/14/2010 United States
Primary
Secondary
Hypokalaemia Hospitalization 10/14/2010 63 Female 187 lb 10/27/2010 Physician Spain
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/1/2010 44 Female 10/27/2010 Consumer United States
Primary
Secondary
Concomitant
Status Epilepticus Hospitalization 3/1/2010 24 Male 10/28/2010 Consumer United States
Primary
Secondary
Sinus Bradycardia Hospitalization 10/5/2010 57 Female 157 lb 10/21/2010 Physician United States
Primary
Concomitant
Hypokalaemia Life Threatening 10/14/2010 63 Female 187 lb 11/4/2010 Physician Spain
Primary
Secondary
Concomitant

Drug Data