Januvia combined with Warfarin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pleural Effusion Other Serious 1/1/2007 61 Female 3/7/2007 Physician United States
Primary
Concomitant
Visual Disturbance 12/7/2006 89 Male 2/16/2007 United States
Primary
Concomitant
Blood Pressure Increased Life Threatening 5/1/2007 70 Male 201 lb 6/19/2007 Physician United States
Primary
Concomitant
Oedema Disability 80 Male 168 lb 2/22/2008 Physician United States
Primary
Concomitant
Pallor Hospitalization 5/4/2008 78 Male 7/22/2008 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 3/24/2009 80 Male 4/3/2009 Consumer United States
Primary
Concomitant
Myasthenia Gravis Other Serious 3/10/2009 69 Female 185 lb 6/9/2009 Other Health Professional United Kingdom
Primary
Concomitant
International Normalised Ratio Abnormal Hospitalization 49 Male 6/17/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 49 Male 7/9/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 45 Male 7/14/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 49 Male 7/15/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Syncope Male 8/22/2009 United States
Primary
Concomitant
Faeces Discoloured 6/1/2009 Male 205 lb 8/22/2009 United States
Primary
Concomitant
Medication Residue 4/13/2009 77 Female 8/14/2009 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 49 Male 9/16/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Palpitations Other Serious 9/5/2009 Male 9/17/2009 Consumer United States
Primary
Concomitant
Ventricular Failure Hospitalization 49 Female 9/14/2009 United States
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 8/21/2009 Male 206 lb 8/24/2009 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 49 Male 9/28/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 49 Male 9/29/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 9/1/2009 66 Male 10/28/2009 Consumer United States
Primary
Concomitant
Pancreatitis Chronic Hospitalization 9/1/2009 66 Male 198 lb 11/4/2009 Physician United States
Primary
Concomitant
Urticaria 7/22/2009 67 Male 11/16/2009 United States
Primary
Concomitant
Peritonitis Other Serious 57 Male 202 lb 11/3/2009 Lawyer United States
Primary
Concomitant
Urinary Retention Hospitalization 61 Male 12/10/2009 United States
Primary
Concomitant
Respiratory Distress Life Threatening 9/18/2008 71 Male 193 lb 12/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Distress Life Threatening 9/18/2008 71 Male 193 lb 12/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Sleep Disorder Life Threatening 10/1/2009 48 Male 353 lb 1/22/2010 Physician United States
Primary
Concomitant
Pneumonia Life Threatening 2/17/2010 77 Male 181 lb 3/30/2010 Physician United States
Primary
Concomitant
Pneumonia Life Threatening 2/17/2010 77 Male 181 lb 4/7/2010 Physician United States
Primary
Concomitant
Pneumonia Other Serious 2/17/2010 77 Male 181 lb 4/12/2010 Physician United States
Primary
Concomitant
Loss Of Consciousness Life Threatening 5/22/2010 70 Female 110 lb 6/3/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 60 Female 99 lb 6/24/2010 Other Health Professional Canada
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 4/30/2010 65 Female 6/24/2010 Japan
Primary
Secondary
Concomitant
Respiratory Distress Life Threatening 9/18/2008 71 Male 194 lb 6/28/2010 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 10/3/2006 52 Male 161 lb 7/12/2010 Other Health Professional United States
Primary
Concomitant
Sepsis Life Threatening 9/18/2008 71 Male 194 lb 7/23/2010 United States
Primary
Secondary
Concomitant
Dizziness Disability 7/14/2010 80 Female 229 lb 8/13/2010 Physician United States
Primary
Concomitant
Dizziness Disability 7/14/2010 80 Female 229 lb 8/30/2010 Physician United States
Primary
Concomitant
Herpes Zoster Other Serious 4/4/2010 Female 183 lb 9/10/2010 Physician Japan
Primary
Secondary
Concomitant
Oropharyngeal Pain 74 Female 217 lb 9/27/2010 Consumer United States
Primary
Concomitant
Dizziness Disability 7/14/2010 80 Female 229 lb 9/29/2010 Other Health Professional United States
Primary
Concomitant
Dizziness Disability 7/14/2010 80 Female 229 lb 10/13/2010 Other Health Professional United States
Primary
Concomitant
Pain In Extremity 74 Male 185 lb 10/18/2010 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 10/8/2010 83 Female 185 lb 10/20/2010 Consumer United States
Primary
Concomitant
Renal Cancer Other Serious 59 Female 224 lb 11/8/2010 Consumer United States
Primary
Concomitant
Pneumonia Bacterial Hospitalization 9/27/2010 80 Male 154 lb 11/18/2010 Physician Japan
Primary
Concomitant
Rash Pruritic Other Serious 1/1/2010 73 Male 202 lb 11/26/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 10/3/2006 52 Male 161 lb 12/2/2010 Other Health Professional United States
Primary
Concomitant
Left Ventricular Dysfunction 11/2/2010 54 Female 158 lb 11/5/2010 United States
Primary
Secondary
Concomitant
Loss Of Consciousness Life Threatening 5/1/2010 77 Female 110 lb 12/15/2010 Physician Japan
Primary
Secondary
Concomitant
Injection Site Pain 9/21/2010 12/23/2010 Consumer United States
Primary
Concomitant
Product Quality Issue 72 Female 1/7/2011 Consumer United States
Primary
Concomitant
Decreased Appetite Hospitalization 12/31/2010 57 Female 1/11/2011 Consumer United States
Primary
Concomitant
International Normalised Ratio Fluctuation Other Serious 1/1/2011 46 Female 3/10/2011 Other Health Professional United Kingdom
Primary
Concomitant
Blister Hospitalization 2/1/2008 83 Female 3/14/2011 Consumer United States
Primary
Secondary
Leukopenia Hospitalization 1/27/2011 81 Male 3/15/2011 Physician Japan
Primary
Concomitant
Feeling Abnormal Other Serious 1/1/2011 72 Female 3/24/2011 Physician Canada
Primary
Concomitant
Confusional State Other Serious 1/1/2011 72 Female 3/25/2011 Physician Canada
Primary
Concomitant
Blister Hospitalization 2/1/2008 83 Female 3/28/2011 Consumer United States
Primary
Secondary
Gait Disturbance Other Serious 1/1/2011 72 Female 4/5/2011 Physician Canada
Primary
Concomitant
Gait Disturbance Other Serious 1/1/2011 72 Female 4/5/2011 Physician Canada
Primary
Concomitant
Pruritus Hospitalization 2/1/2008 83 Female 4/13/2011 Consumer United States
Primary
Secondary
Blood Glucose Increased Other Serious 3/26/2011 77 Female 4/15/2011 Consumer United States
Primary
Concomitant
Stress Other Serious 7/6/2007 75 Male 145 lb 4/19/2011 Lawyer United States
Primary
Concomitant
International Normalised Ratio Fluctuation Other Serious 1/1/2011 46 Female 214 lb 4/20/2011 Other Health Professional United Kingdom
Primary
Concomitant
Chills Death 3/6/2011 4/29/2011 Physician United States
Primary
Secondary
Concomitant
Oesophageal Carcinoma Life Threatening 82 5/12/2011 Other Health Professional United Kingdom
Primary
Concomitant
Rash Erythematous Other Serious 12/1/2010 70 Male 6/22/2011 Physician United Kingdom
Primary
Concomitant
Rash Pruritic Other Serious 12/1/2010 70 Male 6/24/2011 Physician United Kingdom
Primary
Concomitant
Interstitial Lung Disease Hospitalization 1/1/2011 70 Male 7/6/2011 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Death 67 Male 7/7/2011 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/30/2011 82 Female 84 lb 7/25/2011 Physician Japan
Primary
Secondary
Concomitant
Ischaemic Stroke Hospitalization 5/18/2011 69 Male 187 lb 8/4/2011 Physician Israel
Primary
Concomitant
Implantable Defibrillator Insertion Hospitalization 12/1/2010 67 Male 231 lb 8/4/2011 Physician United States
Primary
Concomitant
Oesophageal Carcinoma Disability 11/1/2010 82 8/4/2011 Other Health Professional United Kingdom
Primary
Concomitant
Hepatic Neoplasm Malignant Disability 11/1/2010 82 8/9/2011 Other Health Professional United Kingdom
Primary
Concomitant
Unevaluable Event Death 7/6/2007 75 Male 146 lb 8/11/2011 Lawyer United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 1/1/2011 71 Male 8/11/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Alkaline Phosphatase Increased Other Serious 7/1/2011 70 Female 8/22/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 1/1/2011 71 Male 8/23/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Alkaline Phosphatase Increased Other Serious 7/1/2011 70 Female 8/23/2011 Physician Japan
Primary
Secondary
Concomitant
Lip Exfoliation Life Threatening 10/1/2009 48 Male 353 lb 9/2/2011 Physician United States
Primary
Concomitant
Alanine Aminotransferase Increased Other Serious 7/23/2011 70 Female 117 lb 9/12/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 1/1/2011 71 Male 10/5/2011 Physician Japan
Primary
Secondary
Concomitant
Asthenia Hospitalization 3/1/2009 60 Female 99 lb 11/14/2011 Other Health Professional Canada
Primary
Concomitant
Muscular Weakness Hospitalization 12/11/2011 86 Female 12/20/2011 Pharmacist Japan
Primary
Concomitant
Renal Failure Acute Death 2/2/2011 66 Female 139 lb 12/28/2011 Physician Japan
Primary
Concomitant
Chapped Lips Other Serious 68 Female 161 lb 1/17/2012 Other Health Professional United Kingdom
Primary
Concomitant
Pancytopenia Other Serious 1/20/2012 72 Male 2/10/2012 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 4/7/2012 79 Male 4/19/2012 Physician Japan
Primary
Concomitant
Hypoglycaemia Life Threatening 4/11/2012 53 Male 181 lb 5/4/2012 Physician Japan
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 4/6/2012 65 Male 170 lb 5/7/2012 Physician Japan
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 4/6/2012 65 Male 170 lb 5/14/2012 Physician Japan
Primary
Secondary
Concomitant
Chills 1/1/2011 86 Female 5/24/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Death 4/6/2012 65 Male 170 lb 6/1/2012 Physician Japan
Primary
Secondary
Concomitant
Diarrhoea Other Serious 2/25/2012 56 Male 218 lb 6/13/2012 Other Health Professional United Kingdom
Primary
Concomitant
International Normalised Ratio Fluctuation Other Serious 1/1/2011 46 Female 214 lb 6/15/2012 Other Health Professional United Kingdom
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 4/6/2012 65 Male 170 lb 6/19/2012 Physician Japan
Primary
Secondary
Concomitant
Blood Urea Increased Other Serious 4/6/2012 65 Male 170 lb 6/26/2012 Physician Japan
Primary
Secondary
Concomitant
Restlessness Other Serious 6/4/2012 82 Female 7/3/2012 Pharmacist Japan
Primary
Concomitant
Amnesia Other Serious 6/1/2007 56 Male 7/3/2012 Lawyer United States
Primary
Concomitant
Restlessness Other Serious 6/4/2012 82 Female 7/5/2012 Pharmacist Japan
Primary
Concomitant
Pyrexia Other Serious 1/1/1999 59 Female 187 lb 8/17/2012 Physician United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious Male 193 lb 5/24/2013 Consumer Us
Primary
Secondary
Concomitant
Swelling Other Serious Male 180 lb 4/2/2013 Consumer Us
Primary
Concomitant
Respiratory Failure Life Threatening 12/2010 79 Male 285 lb 6/29/2013 Consumer Us
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 4/7/2012 79 Male 11/6/2013 Consumer Jp
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/7/2012 71 Male 152 lb 9/26/2012 Physician Jp
Primary
Secondary
Concomitant
Interacting
Device Malfunction Hospitalization 8/13/2012 65 Female 9/21/2012 Consumer Country Not Specified
Primary
Secondary
Concomitant
Vena Cava Filter Insertion Other Serious 8/22/2012 61 Male 10/16/2012 Physician Us
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 8/3/2012 62 Male 9/25/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 8/13/2012 65 Female 10/9/2012 Consumer Us
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 7/2012 Female 184 lb 2/15/2013 Physician Ca
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 10/9/2012 53 Male 7/14/2013 Physician Jp
Primary
Concomitant
Cardiac Valve Disease Other Serious 83 Female 109 lb 12/21/2012 Consumer Us
Primary
Secondary
Concomitant
Headache 1/6/2013 90 Female 1/11/2013 Physician Us
Primary
Concomitant
Brain Stem Stroke Death 1/8/2013 90 Female 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Rhinorrhoea 1/2012 75 Female 1/29/2013 Consumer Country Not Specified
Primary
Concomitant
Pain 6/15/2012 85 Female 1/30/2013 Consumer Country Not Specified
Primary
Concomitant
Viral Infection 10/2012 85 Female 1/31/2013 Consumer Country Not Specified
Primary
Secondary
Concomitant
Wound Haemorrhage 8/29/2012 85 Female 1/30/2013 Consumer Country Not Specified
Primary
Concomitant
Pain 9/8/2012 85 Female 1/30/2013 Consumer Country Not Specified
Primary
Secondary
Concomitant
Pruritus Female 170 lb 2/18/2013 Consumer Us
Primary
Concomitant
Osteomyelitis Other Serious 12/15/2012 70 Male 121 lb 3/22/2013 Physician Jp
Primary
Secondary
Concomitant
Weight Decreased 71 Female 118 lb 2/19/2013 Physician Us
Primary
Concomitant
Hypoglycaemia Life Threatening 4/11/2012 53 Male 181 lb 2/8/2013 Physician Jp
Primary
Concomitant
Renal Failure Acute Hospitalization 10/25/2010 74 Female 2/27/2013 Consumer In
Primary
Concomitant
Pneumonia Hospitalization 11/2012 Female 3/6/2013 Consumer Us
Primary
Concomitant
Sneezing 3/2012 Male 3/14/2013 Physician Us
Primary
Concomitant
Prostate Cancer Other Serious 9/2012 73 Male 245 lb 10/31/2012 Consumer Us
Primary
Concomitant
Angina Unstable Hospitalization 10/4/2012 71 Male 172 lb 4/29/2013 Physician Jp
Primary
Secondary
Concomitant
Pneumonia Death 2012 Female 109 lb 5/6/2013 Physician Us
Primary
Concomitant
Weight Decreased Death 6/23/2012 77 Male 152 lb 9/1/2013 Physician Us
Primary
Concomitant
Weight Increased Hospitalization 2013 61 Male 193 lb 6/24/2013 Other Health Professional Us
Primary
Concomitant
Lactic Acidosis Hospitalization 3/28/2013 80 Female 4/30/2013 Consumer De
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 2/28/2013 65 Male 152 lb 5/13/2013 Physician Jp
Primary
Secondary
Concomitant
Pancreatic Enlargement 2012 74 Female 166 lb 4/30/2013 Consumer Country Not Specified
Primary
Concomitant
Movement Disorder 9/2012 86 Female 220 lb 6/17/2013 Consumer Us
Primary
Concomitant
Incorrect Route Of Drug Administration 85 Female 6/6/2013 Other Health Professional Us
Primary
Concomitant
Thrombosis Hospitalization 5/3/2013 74 Female 6/17/2013 Consumer Us
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 2/20/2013 79 Male 9/2/2013 Pharmacist Jp
Primary
Concomitant
Interacting
Pain 71 Female 190 lb 8/23/2013 Consumer Us
Primary
Secondary
Concomitant
Pain Other Serious 66 Female 218 lb 7/30/2013 Consumer Us
Primary
Concomitant
Tumour Associated Fever Hospitalization 2012 66 Male 115 lb 8/1/2013 Other Health Professional Jp
Primary
Concomitant
Liver Function Test Abnormal Other Serious 3/5/2012 56 Male 354 lb 8/22/2013 Physician Us
Primary
Concomitant
Small Intestine Carcinoma Other Serious 1/2013 75 Male 101 lb 8/28/2013 Physician Jp
Primary
Concomitant
Pulmonary Embolism Hospitalization 66 Male 200 lb 9/27/2013 Pharmacist Ca
Primary
Concomitant
Visual Field Defect Other Serious Male 12/28/2012 Consumer Us
Primary
Secondary
Concomitant
Wound Infection Hospitalization 5/16/2012 61 Female 8/1/2013 Consumer Us
Primary
Concomitant

Drug Data