Januvia combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Coronary Artery Disease Hospitalization 1/1/2007 70 Female 5/9/2007 Physician United States
Primary
Concomitant
Decreased Appetite 12/1/2006 60 Female 2/16/2007 United States
Primary
Concomitant
Productive Cough 12/11/2006 61 Male 2/16/2007 United States
Primary
Concomitant
Blood Glucose Increased 11/5/2006 71 Female 2/16/2007 Physician United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 1/1/2007 70 Female 5/23/2007 Physician United States
Primary
Concomitant
Off Label Use Other Serious 1/1/2007 59 Female 172 lb 5/25/2007 Physician United States
Primary
Concomitant
Visual Disturbance 2/18/2007 59 Male 5/17/2007 United States
Primary
Concomitant
Visual Acuity Reduced 2/9/2007 92 Female 141 lb 5/17/2007 Other Health Professional United States
Primary
Concomitant
Tinnitus 2/21/2007 75 Male 5/17/2007 United States
Primary
Concomitant
Upper Respiratory Tract Infection 2/1/2007 74 Female 5/17/2007 United States
Primary
Concomitant
Hepatic Enzyme Increased 12/12/2006 70 Female 5/17/2007 United States
Primary
Concomitant
Dizziness 70 Female 5/17/2007 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 62 Male 223 lb 9/4/2007 Physician United States
Primary
Secondary
Concomitant
Dizziness 12/11/2006 77 Female 114 lb 8/16/2007 Physician United States
Primary
Concomitant
Hepatic Steatosis 12/1/2006 70 Female 8/16/2007 Other Health Professional United States
Primary
Concomitant
Visual Acuity Reduced 2/9/2007 92 Female 141 lb 8/16/2007 Other Health Professional United States
Primary
Concomitant
Palpitations 7/21/2007 73 Male 11/16/2007 United States
Primary
Concomitant
Blood Creatinine Increased 6/19/2007 57 Male 250 lb 11/16/2007 Physician United States
Primary
Concomitant
Vaginal Haemorrhage Hospitalization 78 Female 12/19/2007 Other Health Professional United States
Primary
Concomitant
Vaginal Haemorrhage Hospitalization 10/31/2007 78 Female 1/10/2008 Other Health Professional United States
Primary
Concomitant
Nausea Other Serious 10/1/2007 90 Female 134 lb 1/15/2008 Physician United States
Primary
Concomitant
Urinary Tract Infection Life Threatening 1/1/2007 59 Female 187 lb 2/27/2008 Physician United States
Primary
Secondary
Concomitant
Urine Abnormality 1/1/2007 78 Female 3/4/2008 Consumer United States
Primary
Concomitant
Sudden Death Death 5/8/2008 51 Female 7/7/2008 Physician Canada
Primary
Concomitant
Hypoglycaemia Hospitalization 7/11/2008 64 Female 143 lb 7/28/2008 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/4/2008 73 Female 8/5/2008 Physician France
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2008 77 Female 8/6/2008 Physician Germany
Primary
Concomitant
Sudden Death Death 5/8/2008 51 Female 8/13/2008 Physician Canada
Primary
Concomitant
Hypoglycaemia Hospitalization 7/11/2008 64 Female 143 lb 8/14/2008 Physician Germany
Primary
Secondary
Concomitant
Oropharyngeal Pain 81 Male 8/15/2008 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 7/4/2008 73 Female 134 lb 9/3/2008 Physician France
Primary
Secondary
Concomitant
Medication Residue 7/1/2008 51 Female 11/14/2008 United States
Primary
Concomitant
Back Pain 8/22/2008 87 Female 11/14/2008 United States
Primary
Concomitant
Death Death Male 225 lb 12/23/2008 Consumer United States
Primary
Concomitant
Cardio-respiratory Arrest Death Male 225 lb 1/6/2009 Physician United States
Primary
Concomitant
Urine Abnormality Hospitalization 1/1/2007 Female 1/13/2009 Consumer
Primary
Concomitant
Vitreous Detachment Other Serious 2/1/2007 Male 3/13/2009 Consumer United States
Primary
Concomitant
Cytolytic Hepatitis Hospitalization 9/10/2008 74 Female 203 lb 5/15/2009 Other Health Professional France
Primary
Secondary
Concomitant
Death Death 5/1/2009 Female 96 lb 5/20/2009 Consumer United States
Primary
Concomitant
Right Ventricular Failure Death 5/1/2009 Female 96 lb 5/29/2009 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 73 Male 7/20/2009 Pharmacist United States
Primary
Concomitant
Weight Increased Hospitalization 73 Male 7/28/2009 Pharmacist United States
Primary
Concomitant
Infection Other Serious 6/27/2009 66 Male 8/3/2009 Consumer United States
Primary
Concomitant
Hot Flush Male 8/22/2009 United States
Primary
Concomitant
Photosensitivity Reaction 5/7/2009 Female 8/22/2009 United States
Primary
Concomitant
Flushing 6/1/2009 Male 200 lb 8/23/2009 United States
Primary
Concomitant
Urticaria 7/1/2009 Male 220 lb 8/29/2009 United States
Primary
Concomitant
Pancreatitis Acute Other Serious 6/27/2009 69 Male 9/8/2009 Physician United States
Primary
Concomitant
Syncope Hospitalization 45 Male 213 lb 9/8/2009 United States
Primary
Concomitant
Ventricular Failure Hospitalization 49 Female 9/14/2009 United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 9/7/2008 53 Male 243 lb 9/14/2009 United States
Primary
Concomitant
Therapeutic Response Unexpected Other Serious 1/1/2009 65 Female 175 lb 9/24/2009 Other Health Professional United States
Primary
Concomitant
Pulmonary Hypertension Hospitalization 6/5/2007 44 Male 213 lb 9/18/2009 United States
Primary
Concomitant
Pancreatitis Acute Other Serious 6/27/2009 69 Male 9/28/2009 Physician United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 54 Male 281 lb 9/22/2009 United States
Primary
Concomitant
Spinal Column Stenosis Hospitalization 9/7/2008 53 Male 9/28/2009 United States
Primary
Concomitant
Tricuspid Valve Disease Hospitalization 6/5/2007 44 Male 213 lb 9/25/2009 United States
Primary
Concomitant
Infection Other Serious 6/27/2009 66 Male 10/13/2009 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 9/7/2008 53 Male 243 lb 10/9/2009 United States
Primary
Concomitant
Ventricular Failure Hospitalization 49 Female 10/16/2009 Lawyer United States
Primary
Concomitant
Surgery Hospitalization 55 Female 10/16/2009 Lawyer United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 54 Male 281 lb 10/22/2009 United States
Primary
Concomitant
Sinus Tachycardia Hospitalization 55 Female 10/26/2009 United States
Primary
Concomitant
Wheezing Hospitalization 9/7/2008 53 Male 243 lb 10/27/2009 United States
Primary
Concomitant
Sinus Tachycardia Hospitalization 55 Female 11/4/2009 United States
Primary
Concomitant
Urinary Retention Hospitalization 61 Male 12/10/2009 United States
Primary
Concomitant
Respiratory Failure Other Serious 1/1/2009 Male 267 lb 12/22/2009 Physician United States
Primary
Concomitant
Urinary Retention Hospitalization 61 Male 12/23/2009 Lawyer United States
Primary
Concomitant
Death Death Female 1/5/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 61 Male 236 lb 1/11/2010 United States
Primary
Concomitant
Weight Increased Hospitalization 66 Female 234 lb 1/27/2010 United States
Primary
Concomitant
Pancreatitis Acute Other Serious 6/27/2009 69 Male 2/11/2010 Physician United States
Primary
Concomitant
Sudden Death Death 2/2/2010 81 Female 2/23/2010 Physician United States
Primary
Concomitant
Pancreatitis Acute Other Serious 6/27/2009 69 Male 3/2/2010 Physician United States
Primary
Concomitant
Decreased Appetite Hospitalization 1/23/2010 80 Female 3/12/2010 Physician Japan
Primary
Concomitant
Transplant Rejection Life Threatening 11/1/2009 Female 3/15/2010 Physician United States
Primary
Concomitant
Urinary Retention Other Serious 60 Male 236 lb 4/22/2010 Consumer United States
Primary
Secondary
Concomitant
Condition Aggravated Disability 3/1/2010 74 Male 5/3/2010 Other Health Professional United Kingdom
Primary
Concomitant
Death Death Female 135 lb 5/5/2010 Pharmacist United States
Primary
Concomitant
Weight Increased Hospitalization 66 Female 234 lb 5/6/2010 United States
Primary
Concomitant
Renal Impairment Other Serious 3/1/2010 69 Female 146 lb 5/17/2010 Physician Australia
Primary
Concomitant
Pulmonary Oedema Death Female 135 lb 5/18/2010 Physician United States
Primary
Concomitant
Renal Impairment Other Serious 3/1/2010 69 Female 146 lb 5/21/2010 Physician Australia
Primary
Concomitant
Treatment Noncompliance Required Intervention 4/4/2010 57 Male 220 lb 5/20/2010 Physician United States
Primary
Concomitant
Transplant Rejection Life Threatening 11/1/2009 53 Female 5/27/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 66 Female 234 lb 6/3/2010 United States
Primary
Concomitant
Cardiac Failure Death Female 7/6/2010 Other Health Professional United States
Primary
Concomitant
Stress Hospitalization 1/1/2009 55 Female 150 lb 7/9/2010 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2002 44 Female 172 lb 7/26/2010 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 1/1/2005 47 Female 172 lb 7/26/2010 Consumer United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Other Serious 1/1/2007 49 Female 172 lb 7/26/2010 Consumer United States
Primary
Secondary
Concomitant
Hospitalisation Other Serious 6/1/2010 52 Female 172 lb 7/26/2010 Consumer United States
Primary
Secondary
Concomitant
Visual Impairment Hospitalization 5/1/2010 52 Female 172 lb 8/10/2010 Consumer United States
Primary
Concomitant
Rash Other Serious 7/4/2010 54 Female 280 lb 8/13/2010 Consumer United States
Primary
Concomitant
Renal Impairment Other Serious 3/1/2010 69 Female 123 lb 8/17/2010 Physician Australia
Primary
Concomitant
Polyarthritis Hospitalization 8/8/2010 67 Male 8/19/2010 Physician United States
Primary
Concomitant
Rash Other Serious 7/4/2010 54 Female 280 lb 8/19/2010 Other Health Professional United States
Primary
Concomitant
Rash Other Serious 7/4/2010 54 Female 280 lb 8/20/2010 Other Health Professional United States
Primary
Concomitant
Visual Impairment Life Threatening 8/10/2008 37 Female 161 lb 8/24/2010 Lawyer United States
Primary
Secondary
Concomitant
Visual Impairment Life Threatening 8/10/2008 37 Female 161 lb 8/26/2010 Lawyer United States
Primary
Secondary
Concomitant
Gastric Haemorrhage Male 150 lb 8/27/2010 United States
Primary
Concomitant
Pruritus 73 Male 265 lb 8/28/2010 United States
Primary
Concomitant
Pruritus 6/1/2009 63 Male 360 lb 8/28/2010 Consumer United States
Primary
Concomitant
Pruritus 12/1/2009 72 Male 8/28/2010 Consumer United States
Primary
Concomitant
Swelling Face 1/14/2009 51 Female 273 lb 8/28/2010 Consumer United States
Primary
Concomitant
Polyarthritis Hospitalization 8/8/2010 67 Male 9/3/2010 Physician United States
Primary
Concomitant
Muscle Spasms 9/18/2010 85 Male 10/4/2010 Consumer
Primary
Concomitant
Myocardial Infarction Life Threatening 10/8/2010 83 Female 185 lb 10/20/2010 Consumer United States
Primary
Concomitant
Myocardial Infarction Life Threatening 10/8/2010 83 Female 185 lb 10/27/2010 Physician United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 10/28/2010 69 Male 11/11/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 62 Male 11/17/2010 United States
Primary
Concomitant
Epistaxis Hospitalization 7/24/2010 78 Male 200 lb 8/4/2010 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 6/24/2010 77 Female 119 lb 12/23/2010 Physician Japan
Primary
Concomitant
Hepatic Cirrhosis Hospitalization 1/23/2010 80 Female 12/31/2010 Physician Japan
Primary
Concomitant
Contusion 12/1/2010 63 Male 1/6/2011 Consumer
Primary
Concomitant
Product Quality Issue 72 Female 1/7/2011 Consumer United States
Primary
Concomitant
Pain In Extremity 12/17/2010 57 Female 1/19/2011 Consumer
Primary
Concomitant
Extremity Necrosis Other Serious 12/1/2010 63 Male 174 lb 1/19/2011 Physician France
Primary
Concomitant
Bone Disorder Other Serious Female 1/26/2011 Consumer United States
Primary
Concomitant
Asthenia Hospitalization 8/10/2008 36 Female 161 lb 1/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatitis Other Serious 9/8/2010 69 Female 124 lb 12/16/2010 Physician United States
Primary
Concomitant
Fluid Overload Hospitalization 10/6/2010 37 Female 390 lb 12/3/2010 Other Health Professional United States
Primary
Concomitant
Acne Disability 1/1/2010 69 Male 2/21/2011 Consumer Germany
Primary
Concomitant
Constipation Other Serious 11/1/2010 72 Female 170 lb 2/23/2011 Consumer United States
Primary
Secondary
Concomitant
Coronary Artery Stenosis Hospitalization 4/25/2010 75 Male 199 lb 3/2/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Blood Creatine Phosphokinase Increased Hospitalization 1/14/2011 69 Male 3/3/2011 Physician Germany
Primary
Concomitant
Hernia Repair Other Serious 4/25/2010 75 Male 199 lb 3/7/2011 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Other Serious 12/30/2010 74 Female 225 lb 3/7/2011 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 6/24/2010 77 Female 119 lb 3/9/2011 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 4/25/2010 75 Male 199 lb 3/10/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Hypothyroidism Hospitalization 1/14/2011 69 Male 3/18/2011 Physician Germany
Primary
Secondary
Concomitant
Psoriasis Disability 8/1/2010 69 Male 304 lb 3/18/2011 Physician Germany
Primary
Concomitant
Renal Failure Acute Hospitalization 6/24/2010 77 Female 119 lb 4/1/2011 Physician Japan
Primary
Concomitant
Pulmonary Embolism Death 2/15/2011 64 Female 216 lb 4/7/2011 Physician France
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 3/6/2011 4/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Adverse Event Death 2/15/2011 64 Female 216 lb 4/14/2011 Physician France
Primary
Concomitant
Stress Other Serious 7/6/2007 75 Male 145 lb 4/19/2011 Lawyer United States
Primary
Concomitant
Chills Death 3/6/2011 4/29/2011 Physician United States
Primary
Secondary
Concomitant
Abdominal Pain Other Serious 2/3/2004 38 Female 244 lb 5/19/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Diplopia Hospitalization 8/10/2008 36 Female 161 lb 5/24/2011 Physician United States
Primary
Secondary
Concomitant
Drug Ineffective Death 8/27/2010 74 Male 190 lb 5/24/2011 Physician France
Primary
Secondary
Concomitant
Alopecia 47 Male 179 lb 5/19/2011 Consumer United States
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 3/24/2011 86 Female 101 lb 5/27/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Ineffective Death 8/27/2010 74 Male 190 lb 5/27/2011 Physician France
Primary
Secondary
Concomitant
Gastrooesophageal Reflux Disease Other Serious 2/3/2004 38 Female 244 lb 5/31/2011 Lawyer United States
Primary
Secondary
Concomitant
Resuscitation Hospitalization 3/6/2011 6/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Polymyositis 69 Female 6/5/2011 Physician United States
Primary
Concomitant
Barrett's Oesophagus Other Serious 2/3/2004 38 Female 244 lb 6/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hypothyroidism Hospitalization 1/14/2011 69 Male 6/7/2011 Physician Germany
Primary
Secondary
Concomitant
Malignant Neoplasm Of Ampulla Of Vater Other Serious 8/27/2010 74 Male 190 lb 6/10/2011 Physician France
Primary
Secondary
Concomitant

Drug Data