Januvia combined with Metformin Hydrochloride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Unresponsive To Stimuli Other Serious 1/1/2007 64 Female 1/16/2007 Physician United States
Primary
Concomitant
Muscular Weakness Disability 12/1/2006 70 Female 2/22/2007 Other Health Professional United States
Primary
Concomitant
Muscular Weakness Disability 12/1/2006 70 Female 4/4/2007 Other Health Professional United States
Primary
Concomitant
Overdose 11/16/2006 56 Female 210 lb 2/16/2007 Physician United States
Primary
Concomitant
Pancreatitis Other Serious 1/30/2007 60 Male 5/14/2007 Physician United States
Primary
Concomitant
Nausea 3/1/2007 72 Female 5/17/2007 United States
Primary
Concomitant
Blood Glucose Increased 4/3/2007 62 Female 5/17/2007 United States
Primary
Concomitant
Hypoglycaemia 2/2/2007 58 Female 5/17/2007 United States
Primary
Concomitant
Drug Ineffective 1/10/2007 66 Female 5/17/2007 United States
Primary
Concomitant
Hypoaesthesia Facial 4/9/2007 58 Female 5/17/2007 United States
Primary
Concomitant
Drug Eruption 5/17/2007 Physician United States
Primary
Concomitant
Migraine 3/26/2007 61 Female 4/10/2007 Consumer United States
Primary
Concomitant
Granulocyte Count Increased Hospitalization 7/14/2007 64 Male 8/22/2007 Other Health Professional Denmark
Primary
Concomitant
Granulocyte Count Increased Hospitalization 7/14/2007 64 Male 8/31/2007 Other Health Professional Denmark
Primary
Concomitant
Memory Impairment 51 Female 8/16/2007 United States
Primary
Concomitant
Throat Irritation 6/5/2007 71 Male 8/16/2007 United States
Primary
Concomitant
Rash 4/26/2007 46 Male 8/16/2007 Physician United States
Primary
Concomitant
Hypoglycaemia Hospitalization 80 Male 11/5/2007 Physician Malaysia
Primary
Concomitant
Hypertonia Hospitalization 8/10/2007 55 Male 220 lb 1/2/2008 Physician Switzerland
Primary
Concomitant
Blood Urea Increased Hospitalization 1/1/2007 46 Female 1/18/2008 Physician Malaysia
Primary
Concomitant
Hypoglycaemia Hospitalization Female 1/22/2008 Physician Portugal
Primary
Concomitant
Headache Other Serious 1/1/2008 60 Female 154 lb 2/7/2008 Physician Malaysia
Primary
Concomitant
Ventricular Fibrillation Hospitalization 10/1/2007 72 Female 2/8/2008 Physician Germany
Primary
Concomitant
Acute Myocardial Infarction Other Serious 12/12/2007 77 Male 163 lb 2/8/2008 Physician United States
Primary
Concomitant
Hypoglycaemia Hospitalization 1/1/2008 Female 2/29/2008 Physician Portugal
Primary
Secondary
Bronchospasm Other Serious 2/23/2008 62 Male 3/7/2008 Physician Spain
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection 1/1/2007 61 Female 115 lb 2/15/2008 Physician United States
Primary
Concomitant
Pyrexia Disability 2/20/2008 45 Male 3/17/2008 Physician Malaysia
Primary
Concomitant
Ventricular Fibrillation Hospitalization 10/1/2007 71 Female 161 lb 3/20/2008 Physician Germany
Primary
Concomitant
Hypoglycaemia Other Serious 67 Male 176 lb 4/9/2008 Physician Belgium
Primary
Secondary
Concomitant
Vomiting Other Serious 12/1/2007 55 Female 4/21/2008 Physician Portugal
Primary
Concomitant
Myocardial Infarction Other Serious 2/25/2008 69 Male 150 lb 4/23/2008 Physician Luxembourg
Primary
Concomitant
Prostate Cancer Hospitalization 45 Male 5/14/2008 Physician Malaysia
Primary
Concomitant
Hypoglycaemia Other Serious 5/1/2008 60 Female 6/4/2008 Physician Malaysia
Primary
Concomitant
Tremor Other Serious 5/9/2008 60 Female 6/11/2008 Physician Malaysia
Primary
Concomitant
Arthralgia Hospitalization 6/7/2008 78 Male 6/17/2008 Physician Greece
Primary
Concomitant
Hypoglycaemia Other Serious 5/9/2008 60 Female 6/25/2008 Physician Malaysia
Primary
Concomitant
Polymyalgia Rheumatica Hospitalization 6/7/2008 78 Male 6/27/2008 Physician Greece
Primary
Concomitant
Pancreatitis Other Serious 1/30/2007 60 Male 7/10/2008 Physician United States
Primary
Concomitant
Acute Coronary Syndrome Hospitalization 11/13/2007 60 Male 231 lb 7/30/2008 Physician Switzerland
Primary
Concomitant
Liver Injury Hospitalization 3/10/2008 64 Male 8/13/2008 Other Health Professional Germany
Primary
Concomitant
Acute Coronary Syndrome Hospitalization 11/13/2007 60 Male 231 lb 8/27/2008 Physician Switzerland
Primary
Concomitant
Death Death 6/1/2008 64 Male 9/2/2008 Physician Norway
Primary
Concomitant
Hyperglycaemia Hospitalization 8/5/2008 73 Female 9/15/2008 Physician France
Primary
Concomitant
Hepatitis Acute Hospitalization 9/1/2008 49 Female 9/15/2008 Physician Thailand
Primary
Concomitant
Ischaemic Stroke Hospitalization 5/30/2008 69 Female 9/15/2008 Physician France
Primary
Concomitant
Sudden Death Death 6/1/2008 64 Male 9/18/2008 Physician Norway
Primary
Concomitant
Vasculitis Other Serious 8/1/2008 66 Female 9/19/2008 Physician France
Primary
Concomitant
Liver Injury Hospitalization 3/1/2008 64 Male 198 lb 9/24/2008 Other Health Professional Germany
Primary
Concomitant
Sudden Death Death 6/1/2008 64 Male 9/25/2008 Physician Norway
Primary
Concomitant
Cerebral Infarction Hospitalization 7/24/2008 72 Male 9/29/2008 Other Health Professional Sweden
Primary
Concomitant
Memory Impairment Hospitalization 1/1/2008 72 Male 10/10/2008 Physician France
Primary
Concomitant
Lethargy Disability 8/22/2008 66 Female 183 lb 10/14/2008 Pharmacist Australia
Primary
Concomitant
Bronchospasm Other Serious 2/23/2008 62 Male 10/14/2008 Physician Spain
Primary
Secondary
Concomitant
Influenza Like Illness Hospitalization 1/1/2008 Male 10/20/2008 Consumer United States
Primary
Concomitant
Skin Exfoliation Other Serious 10/18/2008 62 Female 220 lb 10/18/2008 United States
Primary
Concomitant
Gastric Haemorrhage Hospitalization 7/8/2008 64 Male 10/24/2008 Other Health Professional Italy
Primary
Concomitant
Skin Necrosis Other Serious 8/16/2008 66 Female 154 lb 11/6/2008 Physician France
Primary
Concomitant
Hypoglycaemia Other Serious 5/9/2008 60 Female 11/17/2008 Physician Malaysia
Primary
Concomitant
Blood Glucose Increased Other Serious 9/1/2008 57 Male 214 lb 11/17/2008 Pharmacist Australia
Primary
Concomitant
Intentional Drug Misuse Hospitalization 89 Female 11/21/2008 Physician Australia
Primary
Concomitant
Vasculitis Hospitalization 10/1/2008 55 Female 11/24/2008 Physician France
Primary
Concomitant
Gastric Haemorrhage Hospitalization 7/8/2008 64 Male 11/25/2008 Other Health Professional Italy
Primary
Concomitant
Oedema Peripheral Hospitalization 3/21/2008 40 Female 12/3/2008 Other Health Professional Italy
Primary
Concomitant
Pancreatitis Hospitalization 8/12/2008 59 Female 126 lb 12/8/2008 Physician Latvia
Primary
Secondary
Concomitant
Malaise Hospitalization 1/1/2008 63 Male 12/16/2008 Physician Finland
Primary
Concomitant
Toxic Skin Eruption Hospitalization 10/1/2008 55 Female 12/19/2008 Physician France
Primary
Concomitant
Hypertension Hospitalization 1/1/2008 64 Male 12/30/2008 Physician France
Primary
Concomitant
Urticaria Other Serious 12/9/2008 70 Male 236 lb 12/31/2008 Other Health Professional United States
Primary
Concomitant
Urticaria 12/9/2008 70 Male 236 lb 1/7/2009 Other Health Professional United States
Primary
Concomitant
Lethargy Disability 8/22/2008 66 Female 183 lb 1/23/2009 Pharmacist Australia
Primary
Concomitant
Guillain-barre Syndrome Hospitalization 11/1/2008 61 Male 187 lb 1/26/2009 Other Health Professional Australia
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 1/9/2009 53 Female 1/30/2009 Physician France
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 1/12/2009 53 Female 2/2/2009 Physician France
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 1/10/2009 53 Female 2/5/2009 Physician France
Primary
Concomitant
Nausea Hospitalization 2/9/2009 Physician Singapore
Primary
Secondary
Concomitant
Palpitations Hospitalization 2/10/2009 Physician Singapore
Primary
Concomitant
Malaise Hospitalization 1/1/2008 63 Male 2/11/2009 Physician Finland
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 1/10/2009 53 Female 2/13/2009 Physician France
Primary
Concomitant
Renal Failure Hospitalization 12/1/2008 65 Male 2/18/2009 Physician France
Primary
Concomitant
Blood Pressure Increased 11/15/2008 62 Female 291 lb 2/16/2009 Physician United States
Primary
Secondary
Concomitant
Sudden Visual Loss Other Serious 2/18/2009 68 Female 154 lb 2/27/2009 Physician Malaysia
Primary
Concomitant
Renal Failure Hospitalization 11/1/2008 65 Male 2/27/2009 Physician France
Primary
Concomitant
Skin Necrosis Other Serious 8/16/2008 66 Female 154 lb 3/5/2009 Physician France
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 1/10/2009 53 Female 3/6/2009 Physician France
Primary
Concomitant
Toxic Skin Eruption Hospitalization 1/10/2009 53 Female 3/11/2009 Physician France
Primary
Concomitant
Toxic Skin Eruption Hospitalization 1/10/2009 53 Female 3/12/2009 Physician France
Primary
Concomitant
Hypoglycaemia Other Serious 7/25/2008 73 Male 3/16/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Lipase Increased Other Serious 11/1/2008 83 Male 4/6/2009 Physician France
Primary
Concomitant
Somnolence Other Serious 10/11/2008 73 Female 4/10/2009 Physician Spain
Primary
Concomitant
Toxic Skin Eruption Hospitalization 1/10/2009 53 Female 5/1/2009 Physician France
Primary
Concomitant
Renal Failure Acute Other Serious 3/1/2009 70 Female 5/6/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 10/1/2008 55 Female 5/12/2009 Physician France
Primary
Concomitant
Toxic Skin Eruption Hospitalization 1/10/2009 53 Female 5/12/2009 Physician France
Primary
Concomitant
Somnolence Other Serious 10/11/2008 73 Female 5/15/2009 Physician Spain
Primary
Concomitant
Medication Residue 5/2/2008 77 Female 5/8/2009 Pharmacist United States
Primary
Concomitant
Rash Papular 10/16/2008 55 Female 234 lb 5/21/2009 Other Health Professional France
Primary
Concomitant
Myopathy Other Serious 10/3/2008 66 Male 161 lb 5/22/2009 Other Health Professional Greece
Primary
Secondary
Concomitant
Nasal Congestion 11/1/2008 62 Male 185 lb 5/15/2009 United States
Primary
Concomitant
Renal Impairment 50 Female 5/15/2009 Physician United States
Primary
Concomitant
Peripheral Ischaemia 9/1/2008 78 Male 171 lb 5/15/2009 Other Health Professional United States
Primary
Concomitant
Rash Pruritic Male 5/15/2009 Physician United States
Primary
Concomitant
Hyperglycaemia Male 5/15/2009 Physician United States
Primary
Concomitant
Abdominal Distension Female 5/15/2009 United States
Primary
Concomitant
Nausea 50 Female 5/15/2009 Physician United States
Primary
Concomitant
Drug Ineffective 38 Female 5/15/2009 United States
Primary
Concomitant
Anorexia 70 Male 5/15/2009 Physician United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 9/1/2008 72 Female 5/15/2009 United States
Primary
Concomitant
Skin Haemorrhage 1/19/2009 60 Female 165 lb 5/15/2009 Other Health Professional United States
Primary
Concomitant
Respiratory Tract Infection 1/1/2008 66 Female 5/15/2009 United States
Primary
Concomitant
Vomiting 42 Female 5/15/2009 Other Health Professional United States
Primary
Concomitant
Rash 5/1/2008 62 Female 5/15/2009 Other Health Professional United States
Primary
Concomitant
Pollakiuria 11/23/2007 74 Male 5/15/2009 United States
Primary
Concomitant
Pruritus 5/15/2009 Physician United States
Primary
Concomitant
Cheilitis 10/8/2008 59 Female 177 lb 5/15/2009 Physician United States
Primary
Concomitant
Toxic Skin Eruption Hospitalization 10/16/2008 55 Female 234 lb 5/27/2009 Physician France
Primary
Concomitant
Upper Respiratory Tract Infection 12/23/2008 63 Male 230 lb 5/15/2009 Physician United States
Primary
Concomitant
Pain 1/6/2009 65 Male 200 lb 5/15/2009 Physician United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 9/15/2008 65 Male 5/15/2009 United States
Primary
Concomitant
Weight Decreased 7/1/2008 72 Male 5/15/2009 United States
Primary
Concomitant
Rash Pruritic 1/2/2009 64 Male 5/15/2009 United States
Primary
Concomitant
Myalgia 65 Male 5/15/2009 Physician United States
Primary
Concomitant
Pain In Extremity 11/1/2008 62 Female 5/15/2009 United States
Primary
Concomitant
Vision Blurred 12/15/2008 61 Female 5/15/2009 United States
Primary
Concomitant
Toxic Skin Eruption Hospitalization 1/10/2009 53 Female 6/5/2009 Physician France
Primary
Concomitant
Dizziness 65 Female 6/1/2009 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 12/26/2008 Female 5/28/2009 Consumer United States
Primary
Secondary
Concomitant
Myopathy Other Serious 10/3/2008 66 Male 161 lb 6/9/2009 Other Health Professional Greece
Primary
Secondary
Concomitant
Memory Impairment Hospitalization 1/1/2008 72 Male 6/11/2009 Physician France
Primary
Concomitant
Toxic Skin Eruption Hospitalization 1/10/2009 53 Female 6/12/2009 Physician France
Primary
Concomitant
Blood Creatine Phosphokinase Increased Other Serious 10/24/2008 60 Female 205 lb 6/15/2009 Physician France
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 3/1/2009 70 Female 6/25/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 3/1/2009 70 Female 143 lb 7/13/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Wheezing Other Serious 11/1/2008 49 Female 150 lb 7/28/2009 Physician United States
Primary
Concomitant
Renal Failure Other Serious 3/1/2009 70 Female 143 lb 8/5/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Somnolence 3/23/2008 66 Female 8/14/2009 Other Health Professional United States
Primary
Concomitant
Diarrhoea 70 Female 8/14/2009 Physician United States
Primary
Concomitant
No Adverse Event 5/8/2009 74 Female 129 lb 8/14/2009 Other Health Professional United States
Primary
Concomitant
Vision Blurred Disability 1/1/2009 65 Female 203 lb 8/31/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vision Blurred Disability 1/1/2009 65 Female 203 lb 9/3/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 1/10/2009 53 Female 9/15/2009 Physician France
Primary
Concomitant
Granulomatous Liver Disease Hospitalization 6/23/2009 68 Male 9/16/2009 Other Health Professional France
Primary
Secondary
Toxic Skin Eruption Hospitalization 1/10/2009 53 Female 9/18/2009 Physician France
Primary
Concomitant
Urinary Tract Infection Other Serious 9/4/2009 57 Male 9/28/2009 Physician Spain
Primary
Concomitant
Visual Impairment Hospitalization 3/26/2009 66 Female 214 lb 9/30/2009 Other Health Professional France
Primary
Concomitant
Treatment Noncompliance Hospitalization 54 Male 281 lb 9/22/2009 United States
Primary
Concomitant
Hiccups 8/24/2009 73 Male 216 lb 10/1/2009 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 9/25/2009 United States
Primary
Concomitant
Tricuspid Valve Disease Hospitalization 6/5/2007 44 Male 213 lb 9/25/2009 United States
Primary
Concomitant
Urinary Incontinence Hospitalization 8/25/2009 Female 10/12/2009 Other Health Professional Canada
Primary
Concomitant

Drug Data