Itraconazole combined with Vancomycin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Venoocclusive Disease Life Threatening 11/23/2005 63 Female 121 lb 1/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tracheostomy Life Threatening 7/10/2005 42 Female 1/23/2006 United Kingdom
Primary
Secondary
Concomitant
Treatment Noncompliance 13 Male 1/23/2006 Physician United States
Primary
Concomitant
Wound Infection Hospitalization 7/5/2005 65 Male 2/1/2006 Physician Spain
Primary
Secondary
Concomitant
Infection Hospitalization 11/4/2005 65 Male 2/2/2006 Physician Spain
Primary
Secondary
Concomitant
Spinal Laminectomy Other Serious 56 Male 139 lb 3/6/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/13/2003 60 Male 203 lb 3/13/2006 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/15/2003 24 Female 3/14/2006 Physician Japan
Primary
Secondary
Concomitant
Infection Hospitalization 11/4/2005 65 Male 4/11/2006 Physician Spain
Primary
Secondary
Concomitant
Respiratory Distress Other Serious 4/23/2005 50 Male 126 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Sepsis Other Serious 3/12/2006 58 Male 4/21/2006 Korea, Republic Of
Primary
Concomitant
Skin Exfoliation Other Serious 46 Female 6/16/2006 Canada
Primary
Secondary
Concomitant
Spinal Cord Compression Other Serious 1/1/2005 56 Male 139 lb 6/26/2006 Physician Japan
Primary
Concomitant
Tracheal Haemorrhage Hospitalization 5/31/2006 69 Male 6/28/2006 Physician United States
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 11/6/2005 46 Female 153 lb 7/25/2006 Canada
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 7/2/2006 31 Female 180 lb 7/27/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/2/2006 31 Female 180 lb 9/7/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 6/20/2006 58 Male 10/16/2006 Japan
Primary
Concomitant
Skin Exfoliation Other Serious 11/6/2005 46 Female 11/8/2006 Pharmacist Canada
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 6/20/2006 58 Male 1/17/2007 Japan
Primary
Concomitant
Hypovolaemic Shock Hospitalization 5/10/2006 38 Female 1/31/2007 Other Health Professional Spain
Primary
Secondary
Pyrexia Hospitalization 9/27/2006 40 Male 154 lb 3/20/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/20/2006 Male 117 lb 3/22/2007 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 7/15/2006 61 Male 104 lb 4/13/2007 Physician Japan
Primary
Secondary
Concomitant
Pseudomembranous Colitis Other Serious 10/30/2006 Male 161 lb 4/17/2007 Physician Japan
Primary
Secondary
Concomitant
Post Procedural Infection Hospitalization 7/5/2005 65 Male 4/26/2007 Physician Spain
Primary
Secondary
Concomitant
Viral Pharyngitis Other Serious 8/26/2005 19 Male 5/11/2007 Poland
Primary
Secondary
Concomitant
Stomatitis Other Serious 2/23/2007 63 Male 6/15/2007 Physician Japan
Primary
Concomitant
Weight Increased Other Serious 5/1/2007 Female 86 lb 7/11/2007 Physician Japan
Primary
Concomitant
Thrombocytopenia Life Threatening 6/11/2007 75 Male 194 lb 7/19/2007 Physician Greece
Primary
Concomitant
Septic Shock Other Serious 12/6/2004 Male 168 lb 8/14/2007 Physician Italy
Primary
Secondary
Concomitant
Leukoencephalopathy Other Serious 12/5/2006 70 Female 9/3/2007 Pharmacist Japan
Primary
Secondary
Leukoencephalopathy Hospitalization 12/5/2006 70 Female 9/6/2007 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 6/11/2007 75 Male 194 lb 10/4/2007 Physician Greece
Primary
Concomitant
Stomatitis Other Serious 2/23/2007 63 Male 10/22/2007 Physician Japan
Primary
Concomitant
X-ray Abnormal Other Serious 10/7/2002 61 Female 11/1/2007 Physician
Primary
Concomitant
Tachycardia Life Threatening 9/28/2007 21 Female 150 lb 11/21/2007 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 1/21/2007 59 Male 152 lb 1/23/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 1/21/2007 59 Male 152 lb 11/28/2007 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Life Threatening 9/28/2007 21 Female 150 lb 12/3/2007 Physician United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 1/1/2004 Female 2/27/2008 Physician Germany
Primary
Secondary
Tinnitus Hospitalization 47 Female 3/7/2008 Pharmacist United States
Primary
Concomitant
Transaminases Increased Hospitalization 12/30/2007 5 Male 42 lb 4/3/2008 Physician Belgium
Primary
Concomitant
Stomatitis Other Serious 2/20/2007 63 Male 3/31/2008 Physician Japan
Primary
Concomitant
Transaminases Increased Hospitalization 12/30/2007 5 Male 42 lb 4/7/2008 Physician Belgium
Primary
Concomitant
Cardiac Arrest Life Threatening 4/22/2008 82 Female 5/6/2008 Physician Japan
Primary
Concomitant
Urinary Incontinence Other Serious 45 Male 4/25/2008 Physician United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 10/7/2002 61 Female 5/22/2008 Physician Germany
Primary
Concomitant
Cardio-respiratory Arrest Life Threatening 4/22/2008 Female 95 lb 5/29/2008 Physician Japan
Primary
Concomitant
Urinary Incontinence Hospitalization 45 Male 6/6/2008
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 11/24/2007 63 Male 126 lb 6/11/2008 Physician Japan
Primary
Concomitant
Urinary Incontinence Hospitalization 45 Male 6/18/2008
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 11/24/2007 63 Male 126 lb 6/18/2008 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 3/5/2004 38 Male 108 lb 7/11/2008 Physician Japan
Primary
Secondary
Concomitant
Respiratory Distress Other Serious 1 Male 12/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 10/7/2002 Female 1/23/2009 Physician Germany
Primary
Concomitant
Subdural Haematoma Other Serious 12/31/2008 Male 2/6/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 5/5/2004 1 Female 2/12/2009 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 6/11/2007 75 Male 194 lb 2/13/2009 Physician Greece
Primary
Secondary
Concomitant
Syncope Other Serious 12/31/2008 Male 2/20/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 12/31/2008 Male 2/20/2009 Physician United Kingdom
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 10/7/2002 Female 3/10/2009 Physician Germany
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/12/2003 0 Male 13 lb 3/19/2009 France
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 12/30/2007 5 Male 42 lb 4/6/2009 Physician Belgium
Primary
Concomitant
Nephrogenic Diabetes Insipidus Other Serious 12 Male 5/14/2009 Pharmacist United States
Primary
Concomitant
Pyrexia Hospitalization 10/30/2006 45 Male 6/12/2009 Japan
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 6/22/2009 76 Male 7/21/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/18/2009 76 Male 8/10/2009 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Distress Other Serious 4/1/2009 70 Female 144 lb 8/7/2009 Physician United Kingdom
Primary
Concomitant
Respiratory Failure Other Serious 20 Female 9/8/2009 Consumer China
Primary
Concomitant
Abortion Spontaneous Other Serious 20 Female 9/8/2009 Consumer China
Primary
Concomitant
Pleural Effusion Life Threatening 9/3/2009 Female 10/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 29 Male 1/4/2010
Primary
Secondary
Concomitant
Pleural Effusion Life Threatening 9/1/2009 Female 145 lb 1/19/2010 Consumer United States
Primary
Secondary
Concomitant
Septic Embolus Other Serious 24 Female 1/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 3/30/2009 59 Male 1/29/2010 Physician Japan
Primary
Concomitant
Pneumonia Fungal Other Serious 22 Male 2/15/2010 Physician Japan
Primary
Secondary
Concomitant
Hypopyon Hospitalization 48 Female 5/17/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Hypophosphataemia Hospitalization 5/1/2010 45 Female 6/22/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Hypophosphataemia Other Serious 5/1/2010 45 Female 7/23/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Hypoproteinaemia Other Serious 7/22/2010 78 Male 7/26/2010 Physician China
Primary
Secondary
Hypophosphataemia Other Serious 5/1/2010 45 Female 7/30/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Hypoproteinaemia Other Serious 7/22/2010 78 Male 9/13/2010 Physician China
Primary
Secondary
Urinary Tract Infection Other Serious 5/5/2004 1 Female 11/3/2010 Physician United States
Primary
Concomitant
Hypophosphataemia Other Serious 5/1/2010 45 Female 11/17/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Hypophosphataemia Other Serious 5/1/2010 45 Female 12/1/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Hiccups Death 7/30/2010 49 Male 110 lb 12/17/2010 Physician Japan
Primary
Secondary
Concomitant
Endophthalmitis Other Serious 22 Female 12/27/2010 Other Health Professional Croatia (Local Name: Hrvatska)
Primary
Secondary
Endophthalmitis Other Serious 22 Female 12/29/2010 Other Health Professional Japan
Primary
Secondary
Interstitial Lung Disease Death 10/23/2009 62 Male 130 lb 1/7/2011 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 8/6/2010 35 Female 71 lb 1/14/2011 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 13 Male 1/28/2011 Other Health Professional China
Primary
Concomitant
Renal Failure Other Serious 12/1/2009 78 Female 99 lb 12/15/2010 Pharmacist United States
Primary
Secondary
Concomitant
Cholestatic Liver Injury Other Serious 36 Female 3/7/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombocytopenia Death 3/14/2011 4 Male 33 lb 3/24/2011 Consumer Mexico
Primary
Secondary
Concomitant
Multi-organ Failure Hospitalization 3/14/2011 4 Male 33 lb 4/7/2011 Physician Mexico
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Death 7/30/2010 49 Male 110 lb 5/20/2011 Physician Japan
Primary
Secondary
Concomitant
Death Death 4/22/2011 67 Female 5/23/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Disorder Life Threatening 7/25/2010 60 Female 93 lb 5/24/2011 Physician Japan
Primary
Secondary
Concomitant
Pancytopenia Other Serious 58 Male 5/25/2011 Other Health Professional Japan
Primary
Concomitant
Disseminated Intravascular Coagulation Death 7/30/2010 49 Male 110 lb 6/16/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Death 3/18/2011 71 Male 6/28/2011 Physician Japan
Primary
Concomitant
Blood Albumin Decreased Other Serious 12/30/2010 35 Female 6/29/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Hypokalaemia Other Serious 12/29/2010 35 Female 6/30/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Skin Other Serious 7/21/2010 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Life Threatening 3/18/2011 71 Male 7/12/2011 Physician Japan
Primary
Concomitant
Diarrhoea Death 11/6/2010 72 Male 123 lb 7/14/2011 Physician Japan
Primary
Concomitant
Hepatic Failure Death 6/8/2011 62 Male 159 lb 7/20/2011 Consumer Netherlands
Primary
Secondary
Concomitant
Renal Impairment Death 3/18/2011 71 Male 7/21/2011 Physician Japan
Primary
Concomitant
Blood Albumin Decreased Other Serious 12/30/2010 35 Female 7/28/2011 Consumer United States
Primary
Secondary
Concomitant
Fungaemia Death 6/22/2005 46 Male 126 lb 8/2/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Death 50 Male 8/2/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Hypokalaemia Other Serious 12/29/2010 35 Female 8/4/2011 Consumer United States
Primary
Secondary
Concomitant
Bronchopulmonary Aspergillosis Death 63 Female 9/2/2011 Physician Japan
Primary
Concomitant
Febrile Neutropenia Hospitalization 7/1/2008 54 Male 132 lb 9/12/2011 Physician Japan
Primary
Concomitant
Agranulocytosis Other Serious 7/1/2011 71 Male 119 lb 9/19/2011 Other Health Professional Japan
Primary
Concomitant
Pancytopenia Hospitalization 12/1/2008 58 Male 9/21/2011 Other Health Professional Japan
Primary
Concomitant
Pancytopenia Other Serious 58 Male 9/21/2011 Other Health Professional Japan
Primary
Concomitant
Somnolence Hospitalization 3/30/2009 59 Male 9/27/2011 Physician Japan
Primary
Concomitant
Infection Hospitalization 5/2/2011 70 Male 9/27/2011 Other Health Professional Japan
Primary
Concomitant
Bronchopulmonary Aspergillosis Death 66 Female 10/3/2011 Other Health Professional Korea, Republic Of
Primary
Secondary
Concomitant
Neoplasm Malignant Death 11/6/2010 72 Male 123 lb 10/4/2011 Physician Japan
Primary
Concomitant
Death Life Threatening 8/7/2010 Female 10/6/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Hypokalaemia Other Serious 6/9/2011 82 Male 49 lb 10/11/2011 Physician Japan
Primary
Concomitant
Fungal Infection Hospitalization 5/1/2010 45 Female 10/11/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 4/29/2007 61 Female 10/12/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Klebsiella Test Positive Other Serious 4/1/2009 70 Female 144 lb 10/26/2011 Physician United Kingdom
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 8/7/2010 Female 16 lb 11/29/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Other Serious 12/2/2011 59 Male 146 lb 12/12/2011 Consumer Netherlands
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Other Serious 12/2/2011 59 Male 146 lb 12/16/2011 Physician Netherlands
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Other Serious 12/2/2011 59 Male 146 lb 12/29/2011 Physician Netherlands
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Other Serious 12/2/2011 59 Male 146 lb 1/5/2012 Consumer Netherlands
Primary
Secondary
Concomitant
Deafness Hospitalization 1/30/2012 67 Female 2/21/2012 Pharmacist Japan
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Other Serious 12/2/2011 59 Male 146 lb 3/2/2012 Physician Netherlands
Primary
Secondary
Concomitant
Neutrophil Count Decreased Death 10/27/2011 64 Male 170 lb 4/9/2012 Physician Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 7/23/2011 58 Male 4/10/2012 Other Health Professional Japan
Primary
Concomitant
Drug Ineffective Hospitalization 6/22/2011 20 Male 203 lb 4/11/2012 Physician Japan
Primary
Secondary
Concomitant
Myelitis Hospitalization 6/22/2011 20 Male 203 lb 4/11/2012 Physician Japan
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Hospitalization 12/23/2011 70 Male 243 lb 4/20/2012 Physician Spain
Primary
Concomitant
Liver Injury Hospitalization 4/13/2012 64 Male 132 lb 4/26/2012 Physician Estonia
Primary
Concomitant
Pancytopenia Life Threatening 4/29/2007 61 Female 4/24/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Death 2/4/2012 72 Male 93 lb 5/2/2012 Other Health Professional Japan
Primary
Concomitant
Liver Injury Hospitalization 4/13/2012 64 Male 132 lb 5/7/2012 Physician Estonia
Primary
Concomitant
Graft Versus Host Disease In Intestine Other Serious 6/22/2011 20 Male 203 lb 5/16/2012 Physician Japan
Primary
Secondary
Concomitant
Sepsis Life Threatening 1/19/2012 81 Female 5/23/2012 Physician Japan
Primary
Concomitant
Acute Myeloid Leukaemia Hospitalization 12/23/2011 70 Male 243 lb 5/24/2012 Physician Spain
Primary
Concomitant
Renal Failure Acute Hospitalization 7/23/2011 58 Male 132 lb 6/6/2012 Other Health Professional Japan
Primary
Concomitant
Palpitations Life Threatening 6/15/2011 58 Male 132 lb 6/20/2012 Other Health Professional Japan
Primary
Concomitant
Pneumonia Death 4/3/2012 69 Female 163 lb 6/25/2012 Physician Japan
Primary
Concomitant
Renal Failure Acute Other Serious 1/30/2012 67 Female 6/26/2012 Other Health Professional Japan
Primary
Secondary
Concomitant

Drug Data