Itraconazole combined with Omeprazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Therapy Non-responder Life Threatening 9/19/2004 65 Male 1/19/2006 Physician Mexico
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/29/2005 14 Male 1/25/2006 United Kingdom
Primary
Concomitant
Rash Hospitalization 1/12/2006 Female 117 lb 2/15/2006 Physician Portugal
Primary
Concomitant
Renal Failure Acute Hospitalization 6/3/2005 61 Female 132 lb 2/23/2006 Consumer Australia
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/29/2005 14 Male 2/15/2006 United Kingdom
Primary
Concomitant
Platelet Count Decreased Life Threatening 10/10/2005 43 Female 2/27/2006 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 10/10/2005 43 Female 3/20/2006 Japan
Primary
Secondary
Concomitant
Therapy Non-responder Life Threatening 7/15/2005 70 Female 3/23/2006 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 10/10/2005 43 Female 5/3/2006 Japan
Primary
Concomitant
Tachypnoea Other Serious 6/16/2006 Male 98 lb 8/21/2006 Physician Mexico
Primary
Concomitant
Tachypnoea Other Serious 6/16/2006 Male 98 lb 10/6/2006 Physician Mexico
Primary
Concomitant
Thrombocytopenia Death 5/14/2002 65 Female 11/8/2006 Italy
Primary
Secondary
Concomitant
Ventricular Flutter Life Threatening 2/27/2006 20 Female 11/21/2006 Japan
Primary
Concomitant
Thrombocytopenia Life Threatening 9/19/2004 65 Male 12/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatitis Haemorrhagic Hospitalization 5 Female 1/9/2007 Consumer Australia
Primary
Secondary
Concomitant
Pancreatitis Haemorrhagic Hospitalization 5 Female 1/8/2007 Australia
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 45 Female 2/1/2007 Other Health Professional Italy
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/16/2006 20 Female 3/13/2007 Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 10/2/2006 Female 97 lb 3/26/2007 Physician Argentina
Primary
Secondary
Concomitant
Interacting
Blood Amylase Increased Hospitalization 2/6/2007 Male 88 lb 4/3/2007 Other Health Professional France
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 45 Female 4/27/2007 Other Health Professional Italy
Primary
Secondary
Concomitant
Pancreatitis Haemorrhagic Hospitalization 5 Female 5/22/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Pyrexia Life Threatening 4/29/2007 61 5/29/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 5/9/2007 59 Male 130 lb 8/10/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 7/5/2007 36 Male 174 lb 8/17/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Life Threatening 6/22/2007 88 Female 9/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Hospitalization 10/1/2007 54 Female 171 lb 11/6/2007 Physician United States
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Hospitalization 10/1/2007 54 Female 171 lb 11/19/2007 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 1/3/2008 Male 165 lb 3/1/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Micturition Disorder Hospitalization 2/15/2008 73 Male 134 lb 4/1/2008 Physician Japan
Primary
Concomitant
Liver Function Test Abnormal Other Serious 12/17/2007 53 Male 183 lb 4/9/2008 Pharmacist United Kingdom
Primary
Concomitant
Trismus Death 45 Male 4/21/2008 Physician United States
Primary
Secondary
Concomitant
Arteriovenous Fistula Site Complication Hospitalization 1/1/2002 Female 109 lb 4/30/2008 Physician Germany
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 1/3/2008 Male 165 lb 5/5/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 2/15/2008 73 Male 134 lb 4/29/2008 Physician Japan
Primary
Concomitant
Febrile Neutropenia Hospitalization 1/3/2008 Male 165 lb 5/8/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Arteriovenous Fistula Site Complication Hospitalization 10/17/2007 Female 109 lb 5/14/2008 Physician Germany
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 4/5/2008 64 Male 5/16/2008 Physician Japan
Primary
Concomitant
Urinary Incontinence Hospitalization 45 Male 6/6/2008
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/3/2007 56 Female 110 lb 6/2/2008 Physician Japan
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 45 Male 6/18/2008
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Death 11/23/2007 62 Male 6/26/2008 Physician Japan
Primary
Concomitant
Respiratory Failure Other Serious 6/27/2008 70 Male 139 lb 8/7/2008 Physician Japan
Primary
Secondary
Concomitant
Sinus Bradycardia Hospitalization 8/31/2008 53 Female 115 lb 9/12/2008 Other Health Professional United Kingdom
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 9/15/2004 41 Male 121 lb 9/30/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 9/15/2004 41 Male 121 lb 10/1/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 1/1/2003 41 Male 10/14/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Sinus Bradycardia Hospitalization 8/31/2008 53 Female 115 lb 9/24/2008 Physician United Kingdom
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 1/1/2003 41 Male 121 lb 10/20/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Retinoic Acid Syndrome Other Serious 38 Male 10/17/2008 Physician Spain
Primary
Secondary
Concomitant
Ventricular Dysfunction Hospitalization 1/1/2003 41 Male 10/24/2008 United Kingdom
Primary
Concomitant
Interacting
Renal Impairment Hospitalization 7/5/2007 Male 174 lb 10/27/2008 United Kingdom
Primary
Secondary
Concomitant
Phaehyphomycosis Hospitalization 1/1/2001 79 Male 10/27/2008
Primary
Secondary
Concomitant
Red Blood Cell Sedimentation Rate Increased Other Serious 59 Female 10/27/2008
Primary
Secondary
Concomitant
Phaehyphomycosis Hospitalization 1/1/2003 81 Female 10/27/2008
Primary
Secondary
Concomitant
Ventricular Dysfunction Hospitalization 1/1/2003 41 Male 11/28/2008 United Kingdom
Primary
Concomitant
Interacting
Renal Impairment Hospitalization 7/5/2007 Male 174 lb 12/19/2008 United Kingdom
Primary
Secondary
Concomitant
Haemoptysis Life Threatening 9/1/2008 Female 12/24/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Haemoptysis Life Threatening 9/1/2008 Female 1/6/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Rash Vesicular Other Serious 10/2/2007 74 Male 117 lb 12/30/2008 Physician Japan
Primary
Secondary
Concomitant
Hepatitis Death 10/17/2008 28 Female 1/8/2009 Physician Spain
Primary
Concomitant
Ventricular Dysfunction Hospitalization 1/1/2003 1/12/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Pancreatitis Other Serious 1/16/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 7/3/2007 Male 174 lb 1/21/2009 United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Haemorrhagic Hospitalization 2/11/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Culture Positive Other Serious 52 Female 2/16/2009 Germany
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 2/19/2009 Male 3/12/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Ventricular Failure Hospitalization 1/1/2003 3/13/2009 United Kingdom
Primary
Concomitant
Interacting
Febrile Neutropenia Hospitalization 2/19/2009 Male 3/24/2009 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/3/2007 56 Female 110 lb 4/8/2009 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Hospitalization 1/1/2003 41 Male 4/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Pneumonia Other Serious 5/27/2008 4/20/2009 Physician Egypt
Primary
Secondary
Concomitant
Neutropenia Hospitalization 1/1/2003 41 Male 4/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Pneumonia Bacterial Other Serious 11/17/2007 58 Male 192 lb 4/24/2009 Physician Japan
Primary
Secondary
Concomitant
Nephrogenic Diabetes Insipidus Other Serious 12 Male 5/14/2009 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Other Serious 9/26/2007 74 Male 117 lb 5/15/2009 Physician Japan
Primary
Secondary
Concomitant
Virus Serology Test Positive Death 4/17/2009 58 Female 97 lb 6/2/2009 Physician Japan
Primary
Concomitant
Pancreatitis Other Serious 5 Female 6/10/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/3/2007 56 Female 110 lb 6/10/2009 Physician Japan
Primary
Secondary
Concomitant
Shock Haemorrhagic Other Serious 1/1/2009 54 Male 6/19/2009 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 6/1/2009 55 Female 121 lb 6/30/2009 Physician Japan
Primary
Concomitant
Renal Failure Acute Other Serious 38 Male 7/20/2009 Other Health Professional Spain
Primary
Concomitant
Interacting
Virus Serology Test Positive Death 4/17/2009 58 Female 97 lb 7/10/2009 Physician Japan
Primary
Concomitant
Urinary Incontinence Hospitalization 6/22/2009 76 Male 7/21/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Other Serious 6/1/2009 55 Female 121 lb 7/20/2009 Physician Japan
Primary
Concomitant
Malaise Hospitalization 6/8/2009 27 Male 7/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Life Threatening 7/17/2009 Male 169 lb 8/6/2009 Physician Mexico
Primary
Secondary
Concomitant
Pneumonia Death 7/17/2009 Male 169 lb 8/7/2009 Physician Mexico
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/18/2009 76 Male 8/10/2009 Other Health Professional United Kingdom
Primary
Concomitant
Varicella Life Threatening 8/20/2007 58 Male 152 lb 8/10/2009 Physician Japan
Primary
Secondary
Concomitant
Respiratory Distress Other Serious 4/1/2009 70 Female 144 lb 8/7/2009 Physician United Kingdom
Primary
Concomitant
Neutrophil Count Decreased 11/21/2008 77 Female 8/12/2009 Japan
Primary
Secondary
Concomitant
Neutropenia Other Serious 1/1/2009 Female 126 lb 8/21/2009 Consumer United States
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 9/9/2008 Male 168 lb 9/9/2009 Physician United Kingdom
Primary
Concomitant
Shock Haemorrhagic Other Serious 3/31/2009 54 Male 9/10/2009 Physician Japan
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Death 11/23/2007 62 Male 9/12/2009 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 6/1/2007 62 Female 95 lb 9/22/2009 Physician Japan
Primary
Concomitant
Pleural Effusion Life Threatening 9/3/2009 Female 10/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Serum Sickness Hospitalization 8/31/2008 53 Female 115 lb 9/21/2009 Other Health Professional United Kingdom
Primary
Concomitant
Viral Test Positive Hospitalization 9/22/2009 62 Male 194 lb 10/7/2009 Physician Italy
Primary
Secondary
Concomitant
Shock Haemorrhagic Other Serious 3/31/2009 54 Male 10/14/2009 Physician Japan
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Death 11/23/2007 62 Male 10/9/2009 Physician Japan
Primary
Concomitant
Shock Haemorrhagic Other Serious 3/31/2009 54 Male 10/21/2009 Physician Japan
Primary
Secondary
Concomitant
Varicella Life Threatening 8/20/2007 58 Male 152 lb 10/22/2009 Physician Japan
Primary
Concomitant
Transient Ischaemic Attack Other Serious 49 Female 168 lb 11/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Life Threatening 8/20/2007 58 Male 152 lb 11/11/2009 Physician Japan
Primary
Concomitant
Cerebrovascular Accident Death 10/20/2009 Female 11/25/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 10/20/2009 Female 11/30/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 6/1/2007 62 Female 95 lb 11/24/2009 Physician Japan
Primary
Concomitant
Ovarian Cyst Other Serious 12/6/2008 Female 159 lb 12/23/2009 Brazil
Primary
Concomitant
Stem Cell Transplant Hospitalization 6/8/2009 27 Male 12/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Life Threatening 9/1/2009 Female 145 lb 1/19/2010 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 3/22/2009 15 Male 110 lb 2/26/2010 Physician Japan
Primary
Concomitant
Stem Cell Transplant Other Serious 6/8/2009 27 Male 2/18/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Histoplasmosis Other Serious 31 Male 3/30/2010 Physician China
Primary
Interacting
Stem Cell Transplant Other Serious 6/8/2009 27 Male 3/17/2010 United Kingdom
Primary
Secondary
Concomitant
Therapeutic Response Unexpected Other Serious 1/1/2010 57 Male 4/30/2010 Other Health Professional United Kingdom
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 3/11/2010 46 Female 5/18/2010 Physician United Kingdom
Primary
Concomitant
Sympathetic Nerve Injury Other Serious 73 Male 6/7/2010 Consumer Japan
Primary
Concomitant
Nausea Other Serious 10/1/2006 47 Female 6/14/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
White Blood Cell Count Decreased Hospitalization 10/19/2009 54 Male 132 lb 6/21/2010 Other Health Professional Japan
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 3/11/2010 46 Female 6/23/2010 Physician United Kingdom
Primary
Concomitant
Respiratory Failure Other Serious 6/27/2008 70 Male 139 lb 6/24/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/21/2007 63 Female 93 lb 6/28/2010 Physician Japan
Primary
Secondary
Concomitant
No Therapeutic Response Death 2/10/2010 72 Male 168 lb 7/8/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 9/21/2009 37 Female 93 lb 8/9/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 1/9/2009 58 Female 97 lb 7/28/2010 Physician Japan
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 3/11/2009 23 Female 97 lb 8/17/2010 Physician Japan
Primary
Concomitant
Tachycardia Other Serious 65 Female 8/20/2010
Primary
Secondary
Multiple Myeloma Death 6/2/2010 52 Female 159 lb 8/24/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Retinoic Acid Syndrome Other Serious 38 Male 8/26/2010 Physician Spain
Primary
Concomitant
Interacting
Renal Failure Acute Other Serious 38 Male 8/27/2010 Other Health Professional Spain
Primary
Concomitant
Interacting
Venoocclusive Liver Disease Other Serious 3/11/2009 23 Female 97 lb 8/31/2010 Physician Japan
Primary
Concomitant
Retinoic Acid Syndrome Other Serious 38 Male 9/2/2010 Physician Spain
Primary
Concomitant
Interacting
Retinoic Acid Syndrome Other Serious 38 Male 9/2/2010 Physician Spain
Primary
Concomitant
Interacting
Multiple Myeloma Death 6/2/2010 52 Female 159 lb 9/7/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 9/8/2010 21 Male 10/7/2010 Physician Netherlands
Primary
Secondary
Concomitant
Septic Shock Other Serious 10/11/2010 43 Female 10/22/2010 Physician United Kingdom
Primary
Concomitant
Septic Shock Other Serious 10/11/2010 43 Female 10/29/2010 Physician United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 45 Female 11/8/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Vomiting Other Serious 12/17/2009 73 Female 117 lb 11/15/2010 Physician Japan
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 9/8/2010 21 Male 11/16/2010 Physician Netherlands
Primary
Secondary
Concomitant
Neutropenic Sepsis Other Serious 10/11/2010 72 Male 11/23/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Therapeutic Response Decreased Death 1/27/2010 55 Female 128 lb 11/29/2010 Physician Japan
Primary
Concomitant
No Therapeutic Response Death 2/10/2010 72 Male 168 lb 12/9/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/29/2010 49 Male 110 lb 12/13/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/29/2010 49 Male 110 lb 12/13/2010 Physician Japan
Primary
Concomitant
Hiccups Death 7/30/2010 49 Male 110 lb 12/17/2010 Physician Japan
Primary
Secondary
Concomitant
Bronchopulmonary Aspergillosis Hospitalization 11/6/2010 75 165 lb 12/2/2010 Physician Belgium
Primary
Concomitant
Pyrexia Hospitalization 73 Male 12/22/2010 Physician United States
Primary
Secondary
Concomitant

Drug Data