Itraconazole combined with Methylprednisolone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Wound Infection Hospitalization 7/5/2005 65 Male 2/1/2006 Physician Spain
Primary
Secondary
Concomitant
Infection Hospitalization 11/4/2005 65 Male 2/2/2006 Physician Spain
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 1/1/2005 59 Male 3/3/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/15/2003 24 Female 3/14/2006 Physician Japan
Primary
Secondary
Concomitant
Kaposi's Sarcoma Other Serious 11/1/2002 49 Female 11/1/2006 Physician Australia
Primary
Concomitant
Rash Papular Other Serious 8/1/2002 49 Female 11/22/2006 Physician Australia
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/15/2003 24 Female 89 lb 12/29/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 6/15/2003 24 Female 89 lb 1/19/2007 Physician Japan
Primary
Secondary
Concomitant
Shock Other Serious 6/20/2007 Male 7/5/2007 Physician Japan
Primary
Concomitant
Blood Pressure Decreased Other Serious 6/20/2007 Male 7/24/2007 Physician Japan
Primary
Concomitant
Thrombocytopenia Life Threatening 6/11/2007 75 Male 194 lb 7/19/2007 Physician Greece
Primary
Concomitant
Neurological Symptom Hospitalization 58 Male 9/27/2007 Other Health Professional France
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 6/11/2007 75 Male 194 lb 10/4/2007 Physician Greece
Primary
Concomitant
Tachycardia Life Threatening 9/28/2007 21 Female 150 lb 10/16/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/15/2003 24 Female 89 lb 10/22/2007 Physician Japan
Primary
Secondary
Concomitant
Neuropathy Other Serious 52 Male 11/12/2007 Physician Belgium
Primary
Concomitant
Neuropathy Other Serious 52 Male 11/19/2007 Physician Belgium
Primary
Concomitant
Tachycardia Life Threatening 9/28/2007 21 Female 150 lb 11/21/2007 Consumer United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Life Threatening 9/28/2007 21 Female 150 lb 12/3/2007 Physician United States
Primary
Secondary
Concomitant
Creatinine Renal Clearance Decreased Other Serious 53 Female 1/16/2008 Physician Japan
Primary
Concomitant
Respiratory Depression Other Serious 15 Male 4/9/2008 Physician Japan
Primary
Secondary
Concomitant
Trismus Death 45 Male 4/21/2008 Physician United States
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 45 Male 4/25/2008 Physician United States
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 45 Male 6/6/2008
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 45 Male 6/18/2008
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 48 Male 6/20/2008 Other Health Professional Spain
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Death 11/23/2007 62 Male 6/26/2008 Physician Japan
Primary
Concomitant
Tremor Life Threatening 11/22/2004 31 Female 7/7/2008 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 3/22/2006 56 Male 128 lb 7/22/2008 Japan
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 6/24/2008 66 Male 7/24/2008 Physician China
Primary
Concomitant
Respiratory Failure Life Threatening 6/24/2008 66 Male 7/25/2008 Physician China
Primary
Concomitant
Respiratory Failure Life Threatening 6/24/2008 66 Male 7/28/2008 Physician China
Primary
Concomitant
Hepatic Function Abnormal Other Serious 11/29/2005 56 Male 128 lb 7/28/2008 Japan
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 6/24/2008 66 Male 7/30/2008 Physician China
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 12/1/2005 56 Male 128 lb 8/4/2008 Japan
Primary
Secondary
Concomitant
Supraventricular Extrasystoles Other Serious 11 Male 51 lb 4/8/2008 Other Health Professional China
Primary
Secondary
Concomitant
Subcutaneous Nodule Other Serious 49 Female 1/26/2009
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 6/11/2007 75 Male 194 lb 2/13/2009 Physician Greece
Primary
Secondary
Concomitant
Sepsis Death 1/23/2009 71 Male 157 lb 2/20/2009 Physician Japan
Primary
Concomitant
Sepsis Death 1/23/2009 71 Male 157 lb 3/3/2009 Physician Japan
Primary
Concomitant
Virus Serology Test Positive Death 4/17/2009 58 Female 97 lb 6/2/2009 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 6/1/2009 55 Female 121 lb 6/30/2009 Physician Japan
Primary
Concomitant
Hepatitis Cholestatic Other Serious 56 Male 7/16/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Renal Failure Acute Death 6/9/2009 56 Female 130 lb 7/8/2009 Physician Japan
Primary
Concomitant
Virus Serology Test Positive Death 4/17/2009 58 Female 97 lb 7/10/2009 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 6/1/2009 55 Female 121 lb 7/20/2009 Physician Japan
Primary
Concomitant
Respiratory Distress Other Serious 4/1/2009 70 Female 144 lb 8/7/2009 Physician United Kingdom
Primary
Concomitant
Graft Versus Host Disease Death 9/9/2008 Male 168 lb 9/9/2009 Physician United Kingdom
Primary
Concomitant
Viral Infection Other Serious 9/16/2009 Consumer United Kingdom
Primary
Secondary
Tumour Lysis Syndrome Death 11/23/2007 62 Male 9/12/2009 Physician Japan
Primary
Concomitant
Sepsis Death 4/30/2009 71 Female 152 lb 9/3/2009 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 8/11/2009 38 Female 134 lb 9/21/2009 Physician Japan
Primary
Concomitant
Viral Infection Other Serious 10/15/2009 Consumer United Kingdom
Primary
Secondary
Pancytopenia Other Serious 7/31/2009 74 Male 134 lb 11/2/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/29/2009 65 Female 108 lb 11/5/2009 Physician Japan
Primary
Concomitant
Supraventricular Tachycardia Other Serious 5/27/2009 68 Female 104 lb 12/23/2009 Physician Japan
Primary
Concomitant
Renal Failure Acute Life Threatening 6/9/2009 56 Female 130 lb 12/17/2009 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 59 Male 121 lb 12/31/2009 Physician Japan
Primary
Concomitant
Septic Embolus Other Serious 24 Female 1/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 24 Female 2/8/2010 United Kingdom
Primary
Secondary
Sepsis Death 19 Female 2/10/2010 Other Health Professional United Kingdom
Primary
Secondary
Thrombotic Microangiopathy Other Serious 40 Female 4/2/2010 Physician Japan
Primary
Concomitant
Graft Versus Host Disease Other Serious 4/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pseudomonal Sepsis Other Serious 4/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Obliterative Bronchiolitis Other Serious 4/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 4/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Other Serious 4/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Ineffective For Unapproved Indication Other Serious 4/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Graft Versus Host Disease Other Serious 4/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Obliterative Bronchiolitis Death 4/8/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Life Threatening 8/17/2009 59 Male 121 lb 4/2/2010 Physician Japan
Primary
Concomitant
Visual Impairment Disability 3/11/2009 48 Female 84 lb 4/29/2010 Physician Japan
Primary
Concomitant
Pyrexia Life Threatening 8/17/2009 59 Male 121 lb 6/8/2010 Physician Japan
Primary
Concomitant
Stem Cell Transplant Other Serious 3/11/2009 48 Female 84 lb 7/19/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 1/9/2009 58 Female 97 lb 7/28/2010 Physician Japan
Primary
Concomitant
Engraft Failure Hospitalization 9/2/2009 73 Female 126 lb 8/6/2010 Physician Japan
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 9/8/2010 21 Male 10/7/2010 Physician Netherlands
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/30/2009 71 Female 141 lb 9/29/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/29/2009 65 Female 99 lb 9/30/2010 Physician Japan
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 9/8/2010 21 Male 11/16/2010 Physician Netherlands
Primary
Secondary
Concomitant
Pyrexia Life Threatening Male 112 lb 11/24/2010 Physician Japan
Primary
Secondary
Concomitant
Platelet Destruction Increased Other Serious 7/27/2009 74 Male 134 lb 11/8/2010 Physician Japan
Primary
Concomitant
Visual Impairment Other Serious 3/11/2009 48 Female 84 lb 11/8/2010 Physician Japan
Primary
Concomitant
Urinary Tract Infection Bacterial Life Threatening 3/1/2010 74 Female 119 lb 12/9/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 8/16/2010 73 Male 123 lb 12/10/2010 Physician Japan
Primary
Concomitant
Pneumonia Death 10/26/2009 59 Male 121 lb 1/11/2011 Physician Japan
Primary
Secondary
Concomitant
Sepsis Death 1/23/2009 71 Male 112 lb 12/23/2010 Physician Japan
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 8/12/2009 43 Female 134 lb 1/10/2011 Physician Japan
Primary
Concomitant
Sepsis Other Serious 4/30/2009 71 Female 141 lb 1/20/2011 Physician Japan
Primary
Concomitant
Febrile Neutropenia Hospitalization 6/2/2010 3/3/2011 Physician Japan
Primary
Concomitant
Cholestatic Liver Injury Other Serious 36 Female 3/7/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Skin Other Serious 3 Female 3/30/2011 Physician Iran (Islamic Republic Of)
Primary
Secondary
Concomitant
Leukocytosis Life Threatening 12/22/2007 20 Female 4/28/2011 Pharmacist China
Primary
Concomitant
Respiratory Failure Death 10/26/2009 59 Male 121 lb 5/31/2011 Physician Japan
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 2/28/2009 59 Male 141 lb 6/10/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumonia Death 50 Male 8/2/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Acinetobacter Test Positive Hospitalization 9/8/2010 21 Male 8/5/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Skin Life Threatening 3/2/2007 1 Female 20 lb 8/31/2011 Physician Iran (Islamic Republic Of)
Primary
Secondary
Concomitant
No Therapeutic Response Other Serious 2/13/2009 75 Male 165 lb 9/9/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Skin Life Threatening 10/21/2009 22 Female 104 lb 9/26/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Skin Other Serious 10/21/2009 22 Female 104 lb 9/26/2011 Physician Japan
Primary
Secondary
Concomitant
Nephrotic Syndrome Hospitalization 9/16/2010 65 Male 106 lb 9/27/2011 Physician Japan
Primary
Secondary
Concomitant
Multi-organ Failure Life Threatening 5/7/2009 50 Female 90 lb 10/6/2011 Physician Japan
Primary
Concomitant
Cytomegalovirus Mucocutaneous Ulcer Other Serious 2/6/2009 75 Male 165 lb 10/3/2011 Physician Japan
Primary
Secondary
Concomitant
Pseudomonal Sepsis Other Serious 10/21/2009 22 Female 104 lb 10/11/2011 Physician Japan
Primary
Secondary
Concomitant
Klebsiella Test Positive Other Serious 4/1/2009 70 Female 144 lb 10/26/2011 Physician United Kingdom
Primary
Concomitant
Drug Ineffective Death 1/1/2005 59 Male 126 lb 11/4/2011 Physician Japan
Primary
Secondary
Concomitant
Hyperbilirubinaemia Other Serious 5/27/2011 16 Male 12/2/2011 Other Health Professional Spain
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 11/24/2010 49 Male 134 lb 12/7/2011 Physician Japan
Primary
Concomitant
Escherichia Sepsis Hospitalization 2/16/2011 68 Male 137 lb 12/7/2011 Physician Japan
Primary
Concomitant
Rash Other Serious 67 Female 12/13/2011 Other Health Professional Japan
Primary
Concomitant
Cytomegalovirus Chorioretinitis Hospitalization 8/24/2009 21 Male 104 lb 12/20/2011 Physician Japan
Primary
Concomitant
Acute Graft Versus Host Disease Other Serious 3/17/2010 46 Male 159 lb 12/22/2011 Physician Japan
Primary
Concomitant
Pain Of Skin Death 67 Female 12/23/2011 Other Health Professional Japan
Primary
Concomitant
Pseudomonal Sepsis Death 10/21/2009 22 Female 104 lb 2/21/2012 Physician Japan
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Skin Other Serious 8/24/2009 21 Male 104 lb 2/22/2012 Physician Japan
Primary
Concomitant
Blood Creatinine Increased Other Serious 2/24/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 2/28/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Myocarditis Death 76 Male 2/28/2012 Physician Japan
Primary
Concomitant
Condition Aggravated Other Serious 76 Male 3/9/2012 Other Health Professional China
Primary
Secondary
Concomitant
Insomnia Other Serious 4/4/2009 28 Female 115 lb 3/12/2012 Physician Japan
Primary
Secondary
Concomitant
Hypomagnesaemia Hospitalization 1/17/2010 55 Male 168 lb 3/12/2012 Physician Japan
Primary
Secondary
Concomitant
Lung Disorder Life Threatening 1/21/2012 3/22/2012 Physician Japan
Primary
Concomitant
Zygomycosis Other Serious 76 Male 4/3/2012 Other Health Professional China
Primary
Secondary
Concomitant
Lung Disorder Life Threatening 1/21/2012 4/5/2012 Physician Japan
Primary
Concomitant
Urinary Tract Infection Bacterial Hospitalization 3/1/2010 4/19/2012 Physician Japan
Primary
Concomitant
Disseminated Intravascular Coagulation Hospitalization 3/1/2010 4/19/2012 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 9/9/2011 52 Female 110 lb 4/30/2012 Physician Japan
Primary
Concomitant
Drug-induced Liver Injury Hospitalization 12/16/2010 71 Female 187 lb 6/18/2012 Physician Japan
Primary
Concomitant
Non-hodgkin's Lymphoma Death 10/12/2009 43 Male 7/20/2012 Other Health Professional Italy
Primary
Concomitant
Staphylococcal Sepsis Other Serious 6/2/2010 41 Female 123 lb 7/24/2012 Physician Japan
Primary
Concomitant
Hepatic Failure Death 3/17/2010 46 Male 159 lb 8/10/2012 Physician Japan
Primary
Concomitant
Drug-induced Liver Injury Hospitalization 12/16/2010 71 Female 187 lb 8/15/2012 Physician Japan
Primary
Concomitant
Febrile Neutropenia Hospitalization 12/16/2010 71 Female 187 lb 8/20/2012 Physician Japan
Primary
Concomitant
Diarrhoea Hospitalization 10/1/2010 8/20/2012 Physician Austria
Primary
Concomitant
Thrombotic Microangiopathy Death 5/7/2009 51 Female 93 lb 4/18/2013 Physician Jp
Primary
Concomitant
Pseudomonal Sepsis Other Serious 10/21/2009 23 Female 104 lb 4/15/2013 Physician Jp
Primary
Secondary
Concomitant
Viral Sepsis Other Serious 2/13/2011 72 Male 137 lb 3/29/2013 Physician Jp
Primary
Concomitant
Renal Failure Acute Death 10/5/2012 Other Health Professional De
Primary
Secondary
Concomitant
Hypertension Other Serious 17 Female 10/4/2012 Other Health Professional Fr
Primary
Secondary
Interacting
Hypertension Other Serious 17 Female 10/22/2012 Other Health Professional Fr
Primary
Concomitant
Interacting
Hypertension Hospitalization 17 Female 10/27/2012 Other Health Professional Fr
Primary
Concomitant
Interacting
Hypertension Other Serious 17 Female 10/29/2012 Other Health Professional Fr
Primary
Secondary
Rhabdomyolysis 11/25/2012 36 Female 200 lb 1/10/2013 Physician Us
Primary
Concomitant
Pyrexia Hospitalization 12/26/2012 65 Male 2/18/2013 Physician It
Primary
Concomitant
Pneumocystis Jirovecii Pneumonia Death 8/5/2011 59 Male 152 lb 5/28/2013 Physician Jp
Primary
Concomitant
Nephropathy Death 8/24/2011 14 Male 93 lb 4/30/2013 Physician Jp
Primary
Concomitant
Thrombocytopenia Death NotSpecified 6/17/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Sepsis Death 44 Male 8/2/2013 Other Health Professional Es
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Death 26 Female 8/29/2013 Other Health Professional Cn
Primary
Secondary
Concomitant

Drug Data