Itraconazole combined with Lasix

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Required Intervention 11/24/2005 25 Female 2/8/2006 Physician United States
Primary
Concomitant
Skin Ulcer Other Serious 2/12/2006 61 Female 3/10/2006 Physician Japan
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 2/13/2006 61 Female 3/31/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/15/2006 59 Male 6/7/2006 Japan
Primary
Concomitant
Encephalitis Viral Death 10/27/2005 19 Male 7/19/2006 Physician Japan
Primary
Concomitant
Dyskinesia Disability 7/13/2006 58 Male 8/4/2006 Physician Japan
Primary
Concomitant
Myoclonus Disability 7/13/2006 58 Male 8/11/2006 Physician Japan
Primary
Concomitant
Renal Failure Acute Life Threatening 5/15/2006 Male 205 lb 9/8/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/15/2006 59 Male 9/19/2006 Japan
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 5/15/2006 Male 205 lb 3/26/2007 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 4/18/2005 83 Female 4/11/2007 Physician Japan
Primary
Concomitant
Adrenal Insufficiency Hospitalization 1/1/2007 Female 4/18/2007 Physician Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 4/18/2005 83 Female 4/25/2007 Physician Japan
Primary
Concomitant
Sepsis Hospitalization 4/2/2007 63 Male 6/11/2007 Physician Japan
Primary
Concomitant
Rash Other Serious 4/2/2007 71 Male 6/15/2007 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 2/23/2007 63 Male 6/15/2007 Physician Japan
Primary
Concomitant
Adrenal Insufficiency Hospitalization 1/1/2007 Female 7/9/2007 Physician Japan
Primary
Concomitant
Transplant Rejection Hospitalization 5/10/2004 38 Male 108 lb 8/2/2007 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 4/2/2007 71 Male 141 lb 9/17/2007 Physician Japan
Primary
Concomitant
Sternal Fracture Hospitalization 5/10/2004 38 Male 108 lb 9/14/2007 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 4/2/2007 71 Male 141 lb 10/10/2007 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 2/23/2007 63 Male 10/22/2007 Physician Japan
Primary
Concomitant
Transplant Rejection Hospitalization 5/10/2004 38 Male 108 lb 10/24/2007 Physician Japan
Primary
Secondary
Concomitant
Myalgia Required Intervention 2/18/2008 83 Male 169 lb 2/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Other Serious 4/2/2007 71 Male 141 lb 3/19/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 12/6/2007 66 Male 139 lb 4/7/2008 Physician Japan
Primary
Concomitant
Urine Abnormality Life Threatening 9/1/2006 57 Male 4/9/2008 Other Health Professional Japan
Primary
Concomitant
Skin Ulcer Other Serious 2/13/2006 61 Female 4/9/2008 Physician Japan
Primary
Concomitant
Pyrexia Life Threatening 9/1/2006 57 Male 129 lb 4/17/2008 Other Health Professional Japan
Primary
Concomitant
Upper Respiratory Tract Inflammation Other Serious 10/9/2007 56 Male 137 lb 4/24/2008 Physician Japan
Primary
Concomitant
Platelet Count Decreased Life Threatening 1/1/2006 57 Male 129 lb 5/6/2008 Other Health Professional Japan
Primary
Concomitant
Weight Decreased Hospitalization 3/13/2008 47 Male 141 lb 5/14/2008 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 8/1/2007 66 Male 5/19/2008 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Increased Death 1/31/2008 67 Male 126 lb 5/30/2008 Physician Japan
Primary
Concomitant
Sepsis Other Serious 8/1/2007 66 Male 6/10/2008 Other Health Professional Japan
Primary
Concomitant
Upper Respiratory Tract Inflammation Other Serious 9/11/2007 56 Male 137 lb 6/24/2008 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 3/5/2004 38 Male 108 lb 7/11/2008 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 6/27/2008 70 Male 139 lb 8/7/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/23/2008 71 Male 132 lb 8/14/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 7/9/2007 66 Male 139 lb 9/29/2008 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 5/12/2008 71 Male 132 lb 10/7/2008 Physician Japan
Primary
Secondary
Concomitant
Lung Disorder Life Threatening 5/15/2008 Male 112 lb 12/29/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 7/9/2007 66 Male 139 lb 12/23/2008 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 5/12/2008 71 Male 132 lb 12/22/2008 Physician Japan
Primary
Secondary
Concomitant
Rash Vesicular Other Serious 10/2/2007 74 Male 117 lb 12/30/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/12/2008 71 Male 132 lb 1/2/2009 Physician Japan
Primary
Secondary
Concomitant
Right Ventricular Failure Hospitalization 7/27/2008 Male 4/2/2009 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 9/26/2007 74 Male 117 lb 5/15/2009 Physician Japan
Primary
Secondary
Concomitant
Serum Ferritin Increased Other Serious 2/21/2008 59 Female 6/17/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Serum Ferritin Increased Other Serious 2/21/2008 59 Female 6/29/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Serum Ferritin Increased Other Serious 2/21/2008 59 Female 7/10/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 7/9/2007 66 Male 139 lb 7/10/2009 Physician Japan
Primary
Concomitant
Right Ventricular Failure Hospitalization 7/3/2008 Male 7/21/2009 Physician Japan
Primary
Concomitant
Neutrophil Count Decreased 11/21/2008 77 Female 8/12/2009 Japan
Primary
Secondary
Concomitant
Subileus Other Serious 9/11/2007 56 Male 137 lb 8/24/2009 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 6/11/2008 22 Female 9/24/2009 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 3/12/2007 70 Male 157 lb 10/12/2009 Physician Japan
Primary
Concomitant
Upper Respiratory Tract Inflammation Other Serious 9/11/2007 56 Male 137 lb 10/22/2009 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening Male 11/25/2009 Physician Japan
Primary
Concomitant
Neutrophil Count Decreased Other Serious 11/21/2008 77 Female 12/4/2009 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening Male 12/18/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 9/17/2009 73 Female 95 lb 12/15/2009 Physician Japan
Primary
Concomitant
Respiratory Failure Hospitalization 12/16/2008 73 Male 117 lb 3/24/2010 Physician Japan
Primary
Concomitant
Respiratory Failure Hospitalization 12/16/2008 73 Male 117 lb 4/13/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/12/2007 70 Male 157 lb 4/14/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 3/12/2007 70 Male 157 lb 6/10/2010 Physician Japan
Primary
Concomitant
Sudden Death Other Serious 11/14/2008 76 Female 154 lb 6/23/2010 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 6/27/2008 70 Male 139 lb 6/24/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 11/1/2009 74 Male 7/6/2010 Physician Japan
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 9/15/2010 64 Male 192 lb 11/11/2010 Other Health Professional United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 9/15/2010 64 Male 192 lb 12/6/2010 Other Health Professional United States
Primary
Concomitant
Upper Respiratory Tract Inflammation Other Serious 9/11/2007 56 Male 137 lb 11/24/2010 Physician Japan
Primary
Concomitant
Renal Failure Other Serious 12/1/2009 78 Female 99 lb 12/15/2010 Pharmacist United States
Primary
Secondary
Concomitant
Diarrhoea Death 3/3/2011 93 Male 6/2/2011 Physician Japan
Primary
Secondary
Concomitant
C-reactive Protein Increased Hospitalization 12/1/2010 90 Male 6/7/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Level Increased Hospitalization 7/13/2009 65 Male 176 lb 5/27/2011 Physician Japan
Primary
Secondary
Concomitant
Hyperglycaemia Life Threatening 3/30/2011 72 Female 6/15/2011 Other Health Professional Japan
Primary
Concomitant
Herpes Zoster Death 5/2/2011 63 Male 161 lb 6/16/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Blood Glucose Increased Life Threatening 12/30/2009 72 Male 6/17/2011 Physician Japan
Primary
Secondary
Concomitant
Fluid Retention Life Threatening 3/30/2011 72 Female 6/27/2011 Physician Japan
Primary
Concomitant
Pneumonia Death 3/18/2011 71 Male 6/28/2011 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/1/2010 90 Male 6/28/2011 Japan
Primary
Secondary
Concomitant
Hypertransaminasaemia Other Serious 5/2/2011 36 Male 6/28/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Bronchopneumonia Death 3/3/2011 93 Male 6/29/2011 Physician Japan
Primary
Secondary
Concomitant
Sepsis Disability 3/19/2011 75 Male 6/29/2011 Other Health Professional Japan
Primary
Concomitant
Blood Urea Increased Hospitalization 11/15/2008 52 Male 139 lb 7/4/2011 Physician Japan
Primary
Concomitant
Hypokalaemia Other Serious 3/30/2011 72 Female 7/8/2011 Physician Japan
Primary
Concomitant
Pneumonia Life Threatening 3/18/2011 71 Male 7/12/2011 Physician Japan
Primary
Concomitant
Graft Versus Host Disease Other Serious 3/30/2009 52 Male 139 lb 7/13/2011 Physician Japan
Primary
Concomitant
Diarrhoea Death 11/6/2010 72 Male 123 lb 7/14/2011 Physician Japan
Primary
Concomitant
Renal Impairment Death 3/18/2011 71 Male 7/21/2011 Physician Japan
Primary
Concomitant
Pruritus Other Serious 1/1/2006 67 Male 140 lb 7/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 3/14/2005 76 Male 110 lb 8/1/2011 Physician Japan
Primary
Concomitant
Low Cardiac Output Syndrome Death 67 Female 187 lb 7/18/2011 Physician United States
Primary
Concomitant
Delirium Other Serious 5/2/2011 76 Female 8/5/2011 Physician Japan
Primary
Secondary
Concomitant
Hypernatraemia Life Threatening 3/30/2011 72 Female 8/18/2011 Physician Japan
Primary
Concomitant
Sensory Disturbance Death 11/10/2008 76 Female 126 lb 8/24/2011 Physician Japan
Primary
Concomitant
Ataxia Hospitalization 7/17/2011 79 Female 8/30/2011 Other Health Professional Japan
Primary
Concomitant
Engraftment Syndrome Other Serious 3/15/2011 49 Male 9/6/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Death 8/3/2010 79 Male 139 lb 9/7/2011 Physician Japan
Primary
Secondary
Concomitant
Dizziness Other Serious 8/1/2011 83 Female 9/9/2011 Physician Japan
Primary
Concomitant
Sudden Death Death 11/10/2008 76 Female 126 lb 9/14/2011 Physician Japan
Primary
Concomitant
Agranulocytosis Other Serious 7/1/2011 71 Male 119 lb 9/19/2011 Other Health Professional Japan
Primary
Concomitant
Haemorrhagic Cerebral Infarction Death 3/18/2011 75 Male 9/19/2011 Other Health Professional Japan
Primary
Concomitant
Somnolence Hospitalization 3/30/2009 59 Male 9/27/2011 Physician Japan
Primary
Concomitant
Dysarthria Other Serious 8/1/2011 83 Female 9/30/2011 Physician Japan
Primary
Concomitant
Neoplasm Malignant Death 11/6/2010 72 Male 123 lb 10/4/2011 Physician Japan
Primary
Concomitant
Hypokalaemia Other Serious 6/9/2011 82 Male 49 lb 10/11/2011 Physician Japan
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 6/9/2011 82 Male 49 lb 10/20/2011 Physician Japan
Primary
Concomitant
Cardiac Arrest Hospitalization 65 Male 11/1/2011 Other Health Professional Greece
Primary
Concomitant
Interacting
Lymphocyte Count Decreased Hospitalization 8/4/2011 70 Female 11/29/2011 Other Health Professional Japan
Primary
Concomitant
Pneumonia Hospitalization 5/9/2011 77 Male 97 lb 12/6/2011 Physician Japan
Primary
Concomitant
Renal Failure Disability 4/18/2008 70 Female 12/9/2011 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 12/1/2010 90 Male 12/21/2011 Japan
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Other Serious 1/29/2010 52 Male 12/15/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Feeling Abnormal Other Serious 10/22/2011 79 Female 110 lb 1/25/2012 Physician Japan
Primary
Concomitant
Panic Reaction Other Serious 10/22/2011 79 Female 110 lb 1/31/2012 Physician Japan
Primary
Concomitant
Skin Ulcer Death 1/1/2011 68 Male 130 lb 2/13/2012 Other Health Professional Japan
Primary
Concomitant
Drug Interaction Other Serious 83 Female 2/22/2012 Pharmacist Japan
Primary
Interacting
Renal Failure Disability 2/6/2012 48 Male 2/28/2012 Other Health Professional Japan
Primary
Concomitant
Panic Reaction Other Serious 10/22/2011 79 Female 110 lb 2/28/2012 Pharmacist Japan
Primary
Concomitant
Blood Calcium Decreased Other Serious 6/23/2011 65 Male 116 lb 3/14/2012 Physician Japan
Primary
Secondary
Concomitant
Hepatic Failure Other Serious 6/27/2011 71 Male 119 lb 3/14/2012 Physician Japan
Primary
Concomitant
Condition Aggravated Other Serious 2/2/2012 83 Female 3/14/2012 Pharmacist Japan
Primary
Interacting
Renal Failure Acute Hospitalization 7/23/2011 58 Male 4/10/2012 Other Health Professional Japan
Primary
Concomitant
Febrile Neutropenia Life Threatening 5/11/2011 79 Male 139 lb 4/20/2012 Physician Japan
Primary
Concomitant
Oedema Other Serious 5/23/2011 71 Female 5/7/2012 Physician Japan
Primary
Secondary
Concomitant
Drug Interaction Other Serious Female 75 lb 5/11/2012 Pharmacist Japan
Primary
Interacting
Platelet Count Decreased Death 1/1/2012 84 Male 181 lb 5/15/2012 Physician Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 7/23/2011 58 Male 132 lb 6/6/2012 Other Health Professional Japan
Primary
Concomitant
Atypical Mycobacterial Infection Other Serious 6/23/2011 65 Male 116 lb 6/8/2012 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 1/13/2012 84 Male 181 lb 6/15/2012 Physician Japan
Primary
Concomitant
Pneumonia Other Serious 1/13/2012 84 Male 181 lb 6/19/2012 Physician Japan
Primary
Concomitant
Palpitations Life Threatening 6/15/2011 58 Male 132 lb 6/20/2012 Other Health Professional Japan
Primary
Concomitant
Dementia Other Serious Female 75 lb 6/21/2012 Pharmacist Japan
Primary
Interacting
Neutrophil Count Decreased Other Serious 2/17/2012 75 Male 108 lb 7/5/2012 Other Health Professional Japan
Primary
Concomitant
Pyrexia Other Serious 5/23/2011 71 Female 7/9/2012 Physician Japan
Primary
Secondary
Concomitant
Disease Progression Death 1/1/2012 73 Male 7/12/2012 Physician Japan
Primary
Concomitant
Myelodysplastic Syndrome Death 1/1/2012 73 Male 7/17/2012 Physician Japan
Primary
Concomitant
Pneumonia Other Serious 10/1/2011 69 Female 86 lb 8/10/2012 Physician Japan
Primary
Concomitant
Ventricular Fibrillation Life Threatening 1/29/1998 57 Female 154 lb 8/14/2012 Physician Belgium
Primary
Concomitant
Hypomagnesaemia Life Threatening 1/29/1998 57 Female 154 lb 8/14/2012 Physician Belgium
Primary
Concomitant
Blood Calcium Decreased Other Serious 6/23/2011 65 Male 116 lb 8/16/2012 Physician Japan
Primary
Secondary
Concomitant
Bronchospasm Other Serious 3/31/2009 76 Female 8/17/2012 Consumer Japan
Primary
Concomitant
Hyponatraemia Other Serious 88 Female 8/20/2012 Pharmacist Japan
Primary
Concomitant
Ulcer Other Serious 10/17/2007 58 Male 154 lb 2/24/2013 Physician Jp
Primary
Secondary
Concomitant
Sepsis Death 11/18/2009 74 Male 6/26/2013 Consumer Jp
Primary
Secondary
Concomitant
Pneumonia Other Serious 6/23/2011 65 Male 116 lb 10/26/2012 Physician Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/10/2012 75 Male 123 lb 4/30/2013 Physician Jp
Primary
Concomitant
Pulmonary Toxicity Hospitalization 1/2013 51 Female 277 lb 6/24/2013 Other Health Professional Us
Primary
Concomitant

Drug Data