Itraconazole combined with Lansoprazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Venoocclusive Disease Life Threatening 11/23/2005 63 Female 121 lb 1/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urticaria Required Intervention 6/28/2005 Male 168 lb Pharmacist United States
Primary
Concomitant
Anaemia Hospitalization 1/24/2006 Male 2/6/2006 Physician Japan
Primary
Concomitant
Anaemia Hospitalization 1/24/2006 Male 2/15/2006 Physician Japan
Primary
Concomitant
Skin Ulcer Other Serious 2/12/2006 61 Female 3/10/2006 Physician Japan
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 2/13/2006 61 Female 3/31/2006 Physician Japan
Primary
Secondary
Concomitant
Nosocomial Infection Other Serious 3/3/2006 68 Male 220 lb 8/15/2006 Physician United Kingdom
Primary
Concomitant
Red Blood Cell Count Decreased Life Threatening 1/31/2006 58 Male 9/19/2006 Japan
Primary
Concomitant
Visual Acuity Reduced Other Serious 62 Male 11/16/2006 Consumer Japan
Primary
Concomitant
Xanthopsia Other Serious 62 Male 12/21/2006
Primary
Concomitant
Xanthopsia Other Serious 62 Male 12/14/2006 Physician Japan
Primary
Concomitant
Headache Other Serious 9/18/2006 Female 234 lb 4/16/2007 Switzerland
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/4/2007 55 Male 189 lb 5/29/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 4/2/2007 63 Male 6/11/2007 Physician Japan
Primary
Concomitant
Transplant Rejection Hospitalization 5/10/2004 38 Male 108 lb 8/2/2007 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 2/24/2007 Female 88 lb 8/22/2007 Physician Japan
Primary
Concomitant
Reperfusion Arrhythmia Other Serious 8/16/2007 72 Female 8/31/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Leukoencephalopathy Other Serious 12/5/2006 70 Female 9/3/2007 Pharmacist Japan
Primary
Secondary
Leukoencephalopathy Hospitalization 12/5/2006 70 Female 9/6/2007 Physician Japan
Primary
Secondary
Concomitant
Leukoencephalopathy Hospitalization 12/5/2006 70 Female 8/28/2007 Physician Japan
Primary
Secondary
Concomitant
Reperfusion Arrhythmia Life Threatening 8/16/2007 72 Female 9/5/2007 Other Health Professional United Kingdom
Primary
Concomitant
Reperfusion Arrhythmia Life Threatening 8/16/2007 72 Female 9/6/2007 United Kingdom
Primary
Secondary
Concomitant
Reperfusion Arrhythmia Other Serious 8/16/2007 72 Female 9/13/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sternal Fracture Hospitalization 5/10/2004 38 Male 108 lb 9/14/2007 Physician Japan
Primary
Secondary
Concomitant
Reperfusion Arrhythmia Other Serious 72 Female 10/5/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Reperfusion Arrhythmia Life Threatening 8/16/2007 72 Female 10/12/2007 United Kingdom
Primary
Secondary
Concomitant
Reperfusion Arrhythmia Other Serious 8/16/2007 72 Female 10/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Transplant Rejection Hospitalization 5/10/2004 38 Male 108 lb 10/24/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatitis B Virus Other Serious 7/5/2007 72 Male 134 lb 10/31/2007 Physician Japan
Primary
Concomitant
Reperfusion Arrhythmia Other Serious 8/16/2007 72 Female 11/5/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 33 Female 11/5/2007 Physician Turkey
Primary
Concomitant
Confusional State Hospitalization 10/25/2007 12/6/2007 Consumer United Kingdom
Primary
Concomitant
Asthma Other Serious 7/5/2007 72 Male 134 lb 12/28/2007 Physician Japan
Primary
Concomitant
Xanthopsia Other Serious 62 Male 1/28/2008 Physician Japan
Primary
Concomitant
Respiratory Failure Death 4/30/2007 76 Male 2/22/2008 Physician Japan
Primary
Concomitant
Respiratory Failure Death 4/30/2007 76 Male 2/26/2008 Physician Japan
Primary
Concomitant
Tinnitus Hospitalization 47 Female 3/7/2008 Pharmacist United States
Primary
Concomitant
Respiratory Failure Other Serious 4/30/2007 76 Male 3/26/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/30/2007 56 Male 137 lb 3/27/2008 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 11/24/2007 63 Male 126 lb 3/27/2008 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 2/20/2007 63 Male 3/31/2008 Physician Japan
Primary
Concomitant
Vomiting Life Threatening 12/6/2007 66 Male 139 lb 4/7/2008 Physician Japan
Primary
Concomitant
Urine Abnormality Life Threatening 9/1/2006 57 Male 4/9/2008 Other Health Professional Japan
Primary
Concomitant
Skin Ulcer Other Serious 2/13/2006 61 Female 4/9/2008 Physician Japan
Primary
Concomitant
Pyrexia Life Threatening 9/1/2006 57 Male 129 lb 4/17/2008 Other Health Professional Japan
Primary
Concomitant
Pyrexia Hospitalization 2/24/2008 Female 5/5/2008 Physician Japan
Primary
Concomitant
Platelet Count Decreased Life Threatening 1/1/2006 57 Male 129 lb 5/6/2008 Other Health Professional Japan
Primary
Concomitant
Respiratory Failure Death 4/30/2007 76 Male 5/8/2008 Other Health Professional Japan
Primary
Concomitant
Death Death 4/26/2008 56 Male 208 lb 5/19/2008 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/30/2007 56 Male 137 lb 5/19/2008 Physician Japan
Primary
Concomitant
Death Death 56 Male 208 lb 5/20/2008 United Kingdom
Primary
Concomitant
Sepsis Other Serious 8/1/2007 66 Male 5/19/2008 Other Health Professional Japan
Primary
Concomitant
Septic Shock Death 5/1/2008 60 Male 123 lb 5/30/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 9/21/2007 25 Male 112 lb 6/4/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/30/2007 56 Male 137 lb 6/10/2008 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 11/24/2007 63 Male 126 lb 6/11/2008 Physician Japan
Primary
Concomitant
Sepsis Other Serious 8/1/2007 66 Male 6/10/2008 Other Health Professional Japan
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 11/24/2007 63 Male 126 lb 6/18/2008 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 9/21/2007 25 Male 112 lb 6/19/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/21/2007 25 Male 112 lb 6/27/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 1/12/2008 42 Male 134 lb 7/11/2008 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 3/5/2004 38 Male 108 lb 7/11/2008 Physician Japan
Primary
Secondary
Concomitant
Shock Death 4/18/2008 60 Male 123 lb 7/23/2008 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 9/21/2007 25 Male 112 lb 7/28/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/30/2007 56 Male 137 lb 8/18/2008 Physician Japan
Primary
Concomitant
Vomiting Other Serious 7/9/2007 66 Male 139 lb 9/29/2008 Physician Japan
Primary
Concomitant
Weight Increased Other Serious 1/12/2008 42 Male 134 lb 10/24/2008 Physician Japan
Primary
Secondary
Concomitant
Pancytopenia Death 10/22/2008 65 11/14/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 7/9/2007 66 Male 139 lb 12/23/2008 Physician Japan
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 1/15/2009 63 Female 143 lb 2/11/2009 United Kingdom
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 1/5/2009 74 Male 139 lb 3/19/2009 Physician Japan
Primary
Concomitant
Serum Ferritin Increased Other Serious 2/21/2008 59 Female 6/17/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 1/5/2009 74 Male 139 lb 6/26/2009 Physician Japan
Primary
Concomitant
Serum Ferritin Increased Other Serious 2/21/2008 59 Female 6/29/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Serum Ferritin Increased Other Serious 2/21/2008 59 Female 7/10/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 7/9/2007 66 Male 139 lb 7/10/2009 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization Male 7/31/2009 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/23/2007 60 Female 108 lb 8/21/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/23/2007 60 Female 108 lb 9/11/2009 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 6/11/2008 22 Female 9/24/2009 Physician Japan
Primary
Secondary
Concomitant
Sudden Death Other Serious 10/22/2008 65 9/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 8/11/2009 38 Female 134 lb 9/21/2009 Physician Japan
Primary
Concomitant
Eosinophil Count Increased Hospitalization 8/4/2009 88 Male 10/12/2009
Primary
Concomitant
Pruritus Hospitalization 8/4/2009 88 Male 10/16/2009
Primary
Concomitant
Staphylococcal Sepsis Hospitalization 5/8/2009 71 Male 137 lb 10/23/2009 Physician Japan
Primary
Concomitant
Pancytopenia Other Serious 7/31/2009 74 Male 134 lb 11/2/2009 Physician Japan
Primary
Secondary
Concomitant
Pruritus Hospitalization 8/4/2009 88 Male 11/11/2009
Primary
Concomitant
Guillain-barre Syndrome Death 10/23/2009 78 Female 11/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Skin Exfoliation Hospitalization 8/4/2009 88 Male 12/7/2009 Japan
Primary
Concomitant
Reperfusion Arrhythmia Other Serious 8/16/2007 72 Male 12/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Bradycardia Life Threatening 8/16/2007 72 Female 12/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 6/1/2009 Male 12/22/2009 Physician United States
Primary
Concomitant
Multi-organ Failure Death 10/1/2009 52 Male 12/22/2009 Physician Japan
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 67 Female 1/28/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
No Therapeutic Response Death 10/1/2009 52 Male 132 lb 1/29/2010 Physician Japan
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 67 Female 2/25/2010 Other Health Professional Italy
Primary
Secondary
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 67 Female 3/1/2010 Italy
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/10/2009 Female 104 lb 3/4/2010 Physician Japan
Primary
Concomitant
Tremor Other Serious 67 Male 3/24/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tremor Other Serious 77 Male 3/25/2010 Other Health Professional United Kingdom
Primary
Concomitant
Hepatic Function Abnormal Life Threatening 6/28/2009 Male 3/30/2010 Physician Japan
Primary
Concomitant
Tremor Other Serious 67 Male 4/1/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachycardia Life Threatening 3/3/2010 45 Female 240 lb 3/26/2010 Consumer United Kingdom
Primary
Concomitant
Tremor Other Serious 77 Male 4/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Tremor Other Serious 67 Male 4/26/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/1/2009 Male 5/5/2010 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 4/6/2010 39 Male 143 lb 5/25/2010 Consumer Japan
Primary
Concomitant
Visual Impairment Disability 3/11/2009 48 Female 84 lb 4/29/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 4/6/2010 39 Male 143 lb 6/11/2010 Consumer Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 3/23/2007 60 Female 108 lb 6/23/2010 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 56 Male 7/15/2010 Other Health Professional Japan
Primary
Secondary
Interacting
Stem Cell Transplant Other Serious 3/11/2009 48 Female 84 lb 7/19/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 1/1/2008 78 Male 117 lb 8/2/2010 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 56 Male 8/27/2010 Other Health Professional Japan
Primary
Concomitant
Interacting
White Blood Cell Count Decreased Other Serious 5/30/2007 58 Male 163 lb 9/7/2010 Physician Japan
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Other Serious 3/3/2010 76 Male 131 lb 9/20/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 6/10/2009 74 Female 104 lb 9/24/2010 Physician Japan
Primary
Concomitant
Weight Increased Other Serious 1/17/2010 Male 168 lb 11/22/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 6/12/2010 12/1/2010 Consumer Japan
Primary
Concomitant
Platelet Destruction Increased Other Serious 7/27/2009 74 Male 134 lb 11/8/2010 Physician Japan
Primary
Concomitant
Visual Impairment Other Serious 3/11/2009 48 Female 84 lb 11/8/2010 Physician Japan
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 3/3/2010 76 Male 131 lb 12/9/2010 Physician Japan
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 1/1/2010 76 Male 131 lb 12/28/2010 Physician Japan
Primary
Concomitant
Sepsis Hospitalization 4/19/2010 76 Male 121 lb 1/3/2011 Physician Japan
Primary
Concomitant
Blood Bilirubin Increased Other Serious 5/7/2010 37 Male 152 lb 1/5/2011 Physician Japan
Primary
Concomitant
Therapeutic Response Decreased Other Serious 7/1/2009 48 Female 115 lb 1/6/2011 Physician Japan
Primary
Concomitant
Cytomegalovirus Test Positive Death 5/1/2010 54 Female 119 lb 1/10/2011 Physician Japan
Primary
Concomitant
Alanine Aminotransferase Increased Hospitalization 9/26/2010 67 Female 97 lb 1/10/2011 Physician Japan
Primary
Concomitant
Febrile Neutropenia Hospitalization 10/29/2009 53 Female 159 lb 1/10/2011 Physician Japan
Primary
Concomitant
Blood Pressure Increased Other Serious 8/9/2009 48 Female 115 lb 1/10/2011 Physician Japan
Primary
Secondary
Concomitant
Cytomegalovirus Test Positive Hospitalization 5/1/2010 54 Female 119 lb 1/11/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Death 10/26/2009 59 Male 121 lb 1/11/2011 Physician Japan
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 8/12/2009 43 Female 134 lb 1/10/2011 Physician Japan
Primary
Concomitant
Disorientation Death 4/13/2009 52 Male 117 lb 1/10/2011 Physician Japan
Primary
Concomitant
Visual Impairment Hospitalization 72 Male 207 lb 1/28/2011 Other Health Professional United Kingdom
Primary
Concomitant
Bronchopulmonary Aspergillosis Death 1/1/2010 77 Female 2/7/2011 Consumer Japan
Primary
Concomitant
Interstitial Lung Disease Death 1/1/2010 77 Female 2/14/2011 Physician Japan
Primary
Secondary
Concomitant
Haemorrhage Death 1/1/2010 77 Female 2/17/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 7/8/2009 45 Male 1/26/2011 Consumer United States
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Skin Hospitalization 37 Female 115 lb 3/16/2011 Physician Japan
Primary
Concomitant
Eosinophilic Pneumonia Hospitalization 9/9/2009 36 Female 115 lb 4/6/2011 Physician Japan
Primary
Secondary
Concomitant
Rib Fracture Hospitalization 1/1/2010 77 Female 5/4/2011 Consumer Japan
Primary
Secondary
Concomitant
Pulmonary Infarction Other Serious 11/26/2010 62 Female 5/20/2011 Physician Japan
Primary
Concomitant
Neutropenic Sepsis Death 5/10/2011 50 Male 5/20/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Disorder Life Threatening 7/25/2010 60 Female 93 lb 5/24/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 12/3/2010 67 Female 85 lb 5/24/2011 Physician Japan
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 5/10/2011 50 Male 5/28/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Death 10/26/2009 59 Male 121 lb 5/31/2011 Physician Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Death 11/24/2010 80 Female 84 lb 6/1/2011 Physician Japan
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 11/24/2010 80 Female 84 lb 6/6/2011 Physician Japan
Primary
Secondary
Concomitant

Drug Data