Isovorin combined with Kytril

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Guillain-barre Syndrome Other Serious 9/25/2005 Male 214 lb 2/1/2006 Physician South Africa
Primary
Concomitant
Guillain-barre Syndrome Other Serious 9/25/2005 Male 214 lb 2/16/2006 Physician South Africa
Primary
Concomitant
Guillain-barre Syndrome Other Serious 9/25/2005 Male 214 lb 2/20/2006 Physician South Africa
Primary
Concomitant
Guillain-barre Syndrome Other Serious 9/25/2005 Male 214 lb 2/22/2006 Physician South Africa
Primary
Concomitant
Toxic Skin Eruption Disability 2/6/2006 Female 126 lb 3/24/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 2/21/2006 Male 134 lb 4/24/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 2/8/2007 Female 71 lb 4/6/2007 Other Health Professional Japan
Primary
Concomitant
Thrombocytopenia Life Threatening 2/8/2007 Female 71 lb 4/23/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 4/2/2007 Female 108 lb 4/25/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Subdural Haematoma Other Serious 1/11/2007 71 Male 134 lb 5/7/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 4/2/2007 Female 108 lb 5/23/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Shock Death 5/10/2007 Male 97 lb 6/5/2007 Physician Japan
Primary
Secondary
Concomitant
Subdural Haematoma Other Serious 1/11/2007 71 Male 134 lb 6/6/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 8/31/2006 Male 6/13/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Shock Death 5/10/2007 Male 97 lb 7/6/2007 Physician Japan
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization 6/14/2007 Male 8/7/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Appendicitis Perforated Hospitalization 8/5/2007 Male 9/13/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 8/22/2007 Male 10/3/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 9/3/2007 32 Male 205 lb 10/9/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Intestinal Fistula Life Threatening 9/5/2007 Female 10/10/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Abnormal Hospitalization 9/17/2007 Male 10/11/2007 Consumer United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/12/2007 Male 10/12/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Intestinal Obstruction Death 9/5/2007 Female 10/24/2007 Consumer United Kingdom
Primary
Concomitant
Rash Generalised Other Serious 9/4/2007 Female 10/25/2007 Physician United Kingdom
Primary
Concomitant
Wound Dehiscence Death 9/5/2007 Female 11/13/2007 Consumer United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/12/2007 Male 11/19/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Death Death 10/11/2007 Female 12/5/2007 Physician Japan
Primary
Secondary
Concomitant
Death Death 10/11/2007 Female 12/6/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Death Death 10/11/2007 Female 12/10/2007 Physician Japan
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 8/22/2007 Male 12/12/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 10/11/2007 Female 12/12/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Epistaxis Hospitalization 9/17/2007 Male 12/14/2007 Consumer United Kingdom
Primary
Concomitant
Rash Generalised Other Serious 9/4/2007 Female 12/17/2007 Physician United Kingdom
Primary
Concomitant
Oedema Peripheral Other Serious 11/19/2007 Male 12/18/2007 Consumer United Kingdom
Primary
Concomitant
Anaphylactic Shock Life Threatening 10/15/2007 Male 12/19/2007 Consumer United Kingdom
Primary
Concomitant
Intestinal Obstruction Hospitalization 12/3/2007 40 Female 12/27/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 10/11/2007 Female 1/2/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 11/19/2007 Male 1/4/2008 Consumer United Kingdom
Primary
Concomitant
Respiratory Failure Hospitalization 1/5/2008 Male 1/19/2008 Physician United Kingdom
Primary
Concomitant
Intestinal Obstruction Hospitalization 12/8/2007 40 Female 1/23/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Anaphylactic Shock Life Threatening 10/15/2007 Male 1/29/2008 Consumer United Kingdom
Primary
Concomitant
Neuropathy Peripheral Hospitalization 6/14/2007 Male 2/13/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Death 11/19/2007 Male 134 lb 2/20/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Pyrexia Life Threatening 1/5/2008 Male 2/21/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 8/22/2007 Male 2/25/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Cerebral Haemorrhage Life Threatening 2/15/2008 Male 119 lb 2/27/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/12/2007 Male 3/3/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Death 11/19/2007 Male 134 lb 3/4/2008 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/22/2007 Female 3/7/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 12/21/2007 40 Female 3/7/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Haemorrhage Death 9/28/2007 Male 3/11/2008 Physician Japan
Primary
Secondary
Concomitant
Hypersensitivity Hospitalization 1/16/2008 Male 3/13/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 1/12/2008 62 Female 3/14/2008 Physician United Kingdom
Primary
Concomitant
Death Death 2/24/2008 Male 3/19/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 1/17/2008 59 Male 154 lb 3/20/2008 Physician Japan
Primary
Concomitant
Neutrophil Count Decreased Other Serious 7/30/2007 Male 3/21/2008 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 3/6/2008 Male 3/21/2008 Consumer United Kingdom
Primary
Concomitant
Neutrophil Count Decreased Life Threatening 2/26/2008 54 Male 3/24/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/2/2007 Female 101 lb 3/26/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 11/19/2007 Male 3/28/2008 Consumer United Kingdom
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 2/22/2008 Male 157 lb 3/31/2008 Consumer United Kingdom
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 2/22/2008 Male 157 lb 4/3/2008 Consumer United Kingdom
Primary
Concomitant
Interstitial Lung Disease Hospitalization 3/6/2008 Male 4/7/2008 Consumer United Kingdom
Primary
Concomitant
Death Death 10/11/2007 Female 4/8/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Death Death 2/24/2008 Male 4/10/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Cerebral Haemorrhage Life Threatening 2/15/2008 Male 119 lb 4/7/2008 Physician Japan
Primary
Secondary
Concomitant
Cerebral Haemorrhage Life Threatening 2/15/2008 Male 119 lb 4/9/2008 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Artery Thrombosis Other Serious 2/20/2008 73 Male 133 lb 4/14/2008 Physician Japan
Primary
Secondary
Vomiting Other Serious 4/22/2006 Male 130 lb 4/16/2008 Physician Japan
Primary
Secondary
Concomitant
Gastrointestinal Perforation Other Serious 2/13/2008 48 Female 104 lb 4/22/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 7/30/2007 Male 4/23/2008 Physician Japan
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 1/28/2008 Male 165 lb 4/29/2008 Consumer United Kingdom
Primary
Concomitant
Sepsis Death 4/4/2008 Female 101 lb 4/30/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Death 12/6/2007 Male 5/1/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 4/21/2008 62 Female 5/5/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Life Threatening 2/26/2008 54 Male 5/6/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 11/19/2007 Male 5/7/2008 Consumer Japan
Primary
Concomitant
Shock Other Serious 4/1/2008 Female 110 lb 5/16/2008 Consumer Japan
Primary
Secondary
Concomitant
Cerebral Haemorrhage Life Threatening 2/15/2008 Male 119 lb 4/7/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Abnormal Hospitalization 2/5/2008 Male 5/20/2008 Physician Japan
Primary
Secondary
Concomitant
Sneezing Other Serious 3/6/2008 Female 141 lb 5/23/2008 Consumer United Kingdom
Primary
Concomitant
Interstitial Lung Disease Hospitalization 3/10/2008 Male 5/29/2008 Consumer Japan
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 4/4/2008 Female 5/30/2008 Consumer Japan
Primary
Concomitant
Renal Failure Death 12/6/2007 Male 5/30/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Retinal Detachment Hospitalization 5/7/2008 Male 6/4/2008 Consumer Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 3/18/2008 Male 6/5/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/4/2007 Male 6/5/2008 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 3/27/2008 Male 152 lb 6/7/2008 Consumer United Kingdom
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 2/22/2008 Male 157 lb 6/12/2008 Consumer United Kingdom
Primary
Concomitant
Disseminated Intravascular Coagulation Death 12/24/2007 44 Male 6/16/2008 Consumer United Kingdom
Primary
Concomitant
Neutrophil Count Decreased Life Threatening 2/26/2008 54 Male 6/18/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Life Threatening 1/5/2008 Male 6/18/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 4/13/2008 Female 6/21/2008 Consumer United Kingdom
Primary
Concomitant
Peritonitis Life Threatening 4/10/2007 Female 159 lb 6/24/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/22/2007 Female 6/26/2008 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 3/27/2008 Male 152 lb 7/1/2008 Consumer United Kingdom
Primary
Concomitant
Haemorrhage Death 9/28/2007 Male 198 lb 7/1/2008 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 4/7/2008 Female 110 lb 7/2/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Hospitalization 7/30/2007 Male 7/8/2008 Physician Japan
Primary
Secondary
Concomitant
Intestinal Fistula Life Threatening 9/5/2007 Female 7/8/2008 Physician Japan
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 4/13/2008 Female 7/11/2008 Consumer United Kingdom
Primary
Concomitant
Death Death 2/1/2008 Male 7/21/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Hypersensitivity Hospitalization 1/16/2008 Male 7/24/2008 Consumer Japan
Primary
Secondary
Concomitant
Gastrointestinal Perforation Life Threatening 12/15/2007 Female 7/29/2008 Physician Japan
Primary
Secondary
Concomitant
Gastrointestinal Perforation Life Threatening 7/18/2008 Male 7/30/2008 Physician Japan
Primary
Secondary
Concomitant
Gastrointestinal Perforation Life Threatening Female 104 lb 8/1/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Small Intestinal Perforation Life Threatening 3/13/2008 Female 8/4/2008 Physician Japan
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 10/18/2007 Male 8/6/2008 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 3/10/2008 Male 8/6/2008 Consumer Japan
Primary
Secondary
Concomitant
Gastrointestinal Perforation Life Threatening 12/15/2007 Female 8/7/2008 Physician Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Hospitalization 9/18/2007 Male 8/12/2008 Consumer Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 3/18/2008 Male 8/12/2008 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Other Serious 7/31/2008 Male 139 lb 8/12/2008 Physician Japan
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Death 12/24/2007 44 Male 8/15/2008 Consumer United Kingdom
Primary
Concomitant
Intestinal Obstruction Hospitalization 12/21/2007 40 Female 8/18/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Sneezing Other Serious 3/6/2008 Female 141 lb 8/19/2008 Consumer Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/5/2008 Female 105 lb 8/22/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Neuropathy Peripheral Disability 12/7/2006 67 Male 112 lb 8/29/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 7/31/2008 Male 139 lb 9/16/2008 Physician Japan
Primary
Secondary
Concomitant
Hypersensitivity Hospitalization 1/16/2008 Male 9/19/2008 Consumer Japan
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 1/1/2008 Male 119 lb 10/21/2008 Physician United Kingdom
Primary
Concomitant
Interstitial Lung Disease Life Threatening 3/27/2008 Male 152 lb 10/31/2008 Consumer United Kingdom
Primary
Concomitant
Nephrotic Syndrome Other Serious 1/1/2008 Male 154 lb 11/6/2008 Physician Japan
Primary
Secondary
Concomitant
Nephrotic Syndrome Other Serious 5/1/2008 Male 154 lb 11/6/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Neutrophil Count Decreased Life Threatening 2/26/2008 54 Male 11/12/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Epistaxis Hospitalization 9/18/2007 Male 11/25/2008 Consumer Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 3/27/2008 Male 152 lb 12/11/2008 Consumer United Kingdom
Primary
Concomitant
Central Nervous System Lesion Other Serious 9/5/2007 Female 12/16/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Life Threatening 9/5/2008 Male 12/17/2008 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Artery Thrombosis Other Serious 10/1/2007 Female 97 lb 12/22/2008 Physician Japan
Primary
Secondary
Concomitant
Central Nervous System Lesion Other Serious 9/5/2007 Female 12/24/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Angina Pectoris Hospitalization 11/27/2008 Male 139 lb 12/24/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Chest Pain Hospitalization 11/27/2008 Male 139 lb 1/6/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Rectal Perforation Life Threatening 6/16/2008 Male 2/3/2009 Physician Japan
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 12/5/2008 Male 139 lb 2/3/2009 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 2/22/2008 Male 157 lb 2/20/2009 Consumer United Kingdom
Primary
Concomitant
Pyrexia Death 12/25/2008 Female 110 lb 2/24/2009 Other Health Professional Japan
Primary
Concomitant
Haemoptysis Life Threatening 9/5/2008 Male 2/24/2009 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Death 12/5/2008 Female 110 lb 3/5/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Venous Thrombosis Hospitalization 8/20/2007 Male 3/16/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Neuropathy Peripheral Disability 7/1/2006 Male 121 lb 3/19/2009 Other Health Professional Japan
Primary
Concomitant
Mental Disorder Hospitalization 3/6/2009 Male 152 lb 3/21/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Nephrotic Syndrome Other Serious 5/1/2008 Male 154 lb 3/26/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Nephrotic Syndrome Other Serious 1/1/2008 Male 154 lb 3/27/2009 Physician Japan
Primary
Secondary
Concomitant
Hypertension Other Serious 12/23/2007 Male 3/31/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Reactive Psychosis Life Threatening 3/6/2009 Male 152 lb 4/2/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Peritonitis Hospitalization 2/22/2009 Male 132 lb 4/8/2009 Physician Japan
Primary
Secondary
Concomitant
Prinzmetal Angina Hospitalization 11/27/2008 Male 139 lb 4/10/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Peritonitis Hospitalization 2/22/2009 Male 132 lb 4/17/2009 Physician Japan
Primary
Secondary
Concomitant
Anaphylactic Reaction Other Serious 4/1/2008 Female 110 lb 4/17/2009 Consumer Japan
Primary
Secondary
Concomitant

Drug Data