Isosorbide combined with Warfarin Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased Hospitalization 1/11/2006 79 Female 106 lb 3/27/2006 Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Disorder Other Serious 75 Female 180 lb 4/7/2006 United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 1/11/2006 79 Female 106 lb 3/27/2006 Pharmacist United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 2/1/2002 76 Male 196 lb 5/9/2006 Lawyer United States
Primary
Concomitant
Insomnia 11/1/2005 53 Male 155 lb 4/3/2006 Consumer United States
Primary
Concomitant
Dysgeusia 11/20/2005 66 Male 270 lb 4/3/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 4/25/2006 Male 203 lb 4/26/2006 Pharmacist United States
Primary
Concomitant
Thrombosis Life Threatening 6/28/2006 78 Male 230 lb 8/25/2006 Pharmacist United States
Primary
Concomitant
Initial Insomnia 4/1/2005 84 Male 418 lb 10/11/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/1/2006 Female 128 lb 8/17/2006 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 8/1/2006 Female 128 lb 8/17/2006 Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Arrest Other Serious 1/26/2007 37 Female 302 lb 2/1/2007 Consumer United States
Primary
Concomitant
Tremor Other Serious 3/1/2006 66 Male 270 lb 8/17/2006 United States
Primary
Concomitant
Vomiting Other Serious 1/26/2007 37 Female 302 lb 2/14/2007 Consumer United States
Primary
Concomitant
Epistaxis Hospitalization 2/7/2007 74 Male 138 lb 2/12/2007 Pharmacist United States
Primary
Concomitant
Insomnia Male 3/7/2007 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 12/28/2006 55 Male 146 lb 1/3/2007 Pharmacist United States
Primary
Secondary
Concomitant
Blood Glucose Increased Other Serious 1/1/2007 Male 206 lb 3/20/2007 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 2/22/2007 87 Male 133 lb 3/26/2007 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 81 Female 170 lb 11/28/2006 United States
Primary
Concomitant
Glycosylated Haemoglobin Increased Other Serious 1/1/2007 Male 206 lb 4/18/2007 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 5/28/2006 Male 5/7/2007 Physician Australia
Primary
Secondary
Concomitant
Cardiac Pacemaker Malfunction Hospitalization 4/1/2008 77 Male 8/14/2008 United States
Primary
Concomitant
Sinus Headache 4/23/2008 Male 193 lb 8/27/2008 United States
Primary
Concomitant
Stomach Discomfort 6/3/2008 Male 228 lb 8/27/2008 United States
Primary
Concomitant
Flushing 4/1/2008 Male 8/27/2008 United States
Primary
Concomitant
Unevaluable Event 5/23/2008 Female 8/29/2008 United States
Primary
Concomitant
Death Death 8/1/2008 Female 201 lb 9/23/2008 Physician United States
Primary
Concomitant
Fluid Retention Hospitalization 7/28/2008 Female 10/7/2008 Physician United States
Primary
Concomitant
Renal Failure Death 83 Male 10/21/2008 United States
Primary
Concomitant
Fluid Retention Hospitalization 7/28/2008 Female 10/30/2008 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 75 Male 205 lb 10/29/2008 United States
Primary
Concomitant
Weight Decreased Other Serious 9/11/2003 47 Female 260 lb 11/10/2008 United States
Primary
Concomitant
Pain In Extremity 9/1/2008 78 Male 11/14/2008 United States
Primary
Concomitant
Skin Burning Sensation 7/22/2008 Female 11/26/2008 United States
Primary
Concomitant
Paraesthesia 9/5/2008 Male 11/26/2008 United States
Primary
Concomitant
Flushing Male 11/26/2008 United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 9/22/2008 Male 121 lb 12/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Localised Infection 9/4/2008 Female 160 lb 12/12/2008 United States
Primary
Concomitant
Rheumatoid Arthritis 10/21/2008 Female 130 lb 12/12/2008 Consumer United States
Primary
Concomitant
Muscle Spasms 79 Male 220 lb 12/17/2008 United States
Primary
Concomitant
Diverticulitis 5/1/2008 65 Male 185 lb 12/17/2008 United States
Primary
Concomitant
Intermittent Claudication 9/1/2008 78 Male 171 lb 2/16/2009 Physician United States
Primary
Concomitant
Multiple Injuries Death 67 Male 3/12/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 8/12/2003 60 Male 216 lb 4/3/2009 United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 4/19/2006 67 Male 180 lb 5/1/2009 United States
Primary
Concomitant
Supraventricular Extrasystoles Other Serious Male 216 lb 5/15/2009 United Kingdom
Primary
Concomitant
Coagulopathy Hospitalization 4/1/2009 Male 5/14/2009 Pharmacist United States
Primary
Concomitant
Peripheral Ischaemia 9/1/2008 78 Male 171 lb 5/15/2009 Other Health Professional United States
Primary
Concomitant
Skin Induration Death 10/1/2002 77 Female 187 lb 5/26/2009 Physician United States
Primary
Concomitant
Skin Induration Death 10/1/2002 77 Female 187 lb 5/26/2009 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 59 Male 215 lb 6/1/2009 United States
Primary
Concomitant
Subcutaneous Nodule Death 10/1/2002 77 Female 187 lb 6/17/2009 Physician United States
Primary
Concomitant
Unevaluable Event Death 67 Male 6/30/2009 Lawyer United States
Primary
Concomitant
Renal Function Test Abnormal Disability 1/1/2006 Male 7/6/2009 Consumer United States
Primary
Concomitant
Unevaluable Event Hospitalization 7/1/2007 48 Male 7/28/2009 Consumer United States
Primary
Concomitant
Renal Disorder Death 67 Male 8/3/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 7/1/2007 48 Male 456 lb 9/1/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 90 Female 9/2/2009 United States
Primary
Concomitant
Unevaluable Event Death 68 Male 9/1/2009 Lawyer United States
Primary
Concomitant
Wheezing Hospitalization 78 Male 9/21/2009 United States
Primary
Concomitant
Vomiting Death 86 Female 9/23/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 9/23/2009 United States
Primary
Concomitant
Weight Increased Other Serious 55 Male 215 lb 9/28/2009 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 4/23/2007 54 Female 258 lb 9/24/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 10/10/2009 United States
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 8/4/2009 84 Female 10/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 55 Male 215 lb 10/17/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 10/16/2009 Lawyer United States
Primary
Concomitant
Hyperhidrosis Hospitalization 8/28/2009 67 Male 123 lb 8/31/2009 Pharmacist United States
Primary
Concomitant
Prothrombin Time Prolonged Death 68 Male 10/26/2009 United States
Primary
Concomitant
Weight Increased Other Serious 55 Male 215 lb 11/4/2009 United States
Primary
Concomitant
Waist Circumference Increased Hospitalization 72 Male 256 lb 11/16/2009 United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 90 Female 11/18/2009 United States
Primary
Concomitant
Unevaluable Event Death 72 Female 11/18/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 61 Female 11/17/2009 Lawyer United States
Primary
Concomitant
Surgery Hospitalization 81 Female 11/18/2009 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 4/23/2007 54 Female 258 lb 11/18/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 64 Female 155 lb 11/20/2009 United States
Primary
Concomitant
Ventricular Fibrillation Death 82 Male 11/17/2009 Lawyer United States
Primary
Concomitant
Pain Death 68 Male 11/24/2009 United States
Primary
Concomitant
Weight Increased Other Serious 55 Male 215 lb 11/24/2009 Consumer United States
Primary
Concomitant
Pancreatitis Hospitalization 6/29/2007 Male 11/30/2009 Physician United States
Primary
Concomitant
Wound Complication Other Serious 1/1/2000 Female 12/1/2009 Physician United States
Primary
Concomitant
Urinary Retention Hospitalization 61 Male 12/1/2009 United States
Primary
Concomitant
Wound Secretion Hospitalization Male 12/1/2009 Lawyer United States
Primary
Concomitant
Wheezing Other Serious 1/1/2007 74 Male 231 lb 12/17/2009 Other Health Professional United States
Primary
Concomitant
Pain In Extremity 72 Female 221 lb 12/22/2009 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 55 Male 215 lb 12/23/2009 Lawyer United States
Primary
Concomitant
Urinary Retention Hospitalization 61 Male 12/23/2009 Lawyer United States
Primary
Concomitant
Occult Blood Positive Other Serious 12/22/2009 73 Female 1/11/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 61 Male 236 lb 1/11/2010 United States
Primary
Concomitant
Vomiting Hospitalization 81 Female 1/14/2010 United States
Primary
Concomitant
Urticaria 65 Male 208 lb 1/8/2010 United States
Primary
Concomitant
Occult Blood Positive Other Serious 12/22/2009 73 Female 1/27/2010 Consumer United States
Primary
Secondary
Concomitant
Occult Blood Positive Other Serious 12/22/2009 73 Female 178 lb 1/29/2010 Physician United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 79 Male 1/23/2010 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 Male 250 lb 2/12/2010 Other Health Professional United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 72 Male 256 lb 2/5/2010 United States
Primary
Concomitant
Weight Increased Hospitalization Male 2/5/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 10/1/2007 57 Male 2/25/2010 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 81 Female 2/19/2010 United States
Primary
Concomitant
Wheezing Other Serious 1/1/2007 74 Male 231 lb 3/2/2010 Other Health Professional United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 12/30/2009 69 Female 4/27/2010 Other Health Professional United States
Primary
Concomitant
Urinary Retention Other Serious 60 Male 236 lb 4/22/2010 Consumer United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2008 90 Female 90 lb 4/29/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious Male 5/13/2010 United States
Primary
Concomitant
Hip Fracture Other Serious 1/1/2008 90 Female 90 lb 5/20/2010 United States
Primary
Secondary
Concomitant
Death Death 1/26/2010 65 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious Male 202 lb 7/1/2010 United States
Primary
Concomitant
Liver Function Test Abnormal Hospitalization Female 7/1/2010 Physician United States
Primary
Concomitant
Nausea 7/1/2007 67 Female 160 lb 7/14/2010 Consumer United States
Primary
Concomitant
Vomiting 4/29/2007 57 Female 417 lb 7/15/2010 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 2/22/2008 84 Female 7/21/2010 Lawyer United States
Primary
Concomitant
Insomnia 4/24/2008 64 Male 230 lb 7/21/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/11/2006 69 Male 202 lb 7/22/2010 United States
Primary
Concomitant
Sinus Bradycardia Other Serious 73 Female 88 lb 7/22/2010
Primary
Secondary
Feeling Abnormal 2/18/2009 70 Female 8/3/2010 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 86 Female 7/26/2010 United States
Primary
Concomitant
Thrombosis Other Serious 1/1/2010 62 Male 8/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea 4/25/2010 74 Female 150 lb 8/29/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 54 Male 250 lb 8/30/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/11/2006 69 Male 202 lb 8/28/2010 United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/16/2007 78 Female 130 lb 9/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pharyngeal Oedema Other Serious 3/1/2008 50 Male 328 lb 9/15/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/17/2008 78 Female 9/16/2010 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 2/22/2008 84 Female 9/17/2010 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious Male 9/23/2010 United States
Primary
Concomitant
Ventricular Arrhythmia Other Serious 3/24/2008 81 Male 10/7/2010 Consumer United States
Primary
Concomitant
Pharyngeal Oedema Other Serious 2/1/2010 73 Male 10/18/2010 Other Health Professional United States
Primary
Concomitant
Visual Impairment Other Serious 11/25/2010 Female 101 lb 12/2/2010 Consumer United States
Primary
Secondary
Concomitant
Peripheral Ischaemia Death 1/30/2011 81 Female 117 lb 6/3/2011 Other Health Professional Switzerland
Primary
Concomitant
Dyspnoea Other Serious 82 Male 5/23/2011 Consumer United States
Primary
Concomitant
Peripheral Ischaemia Other Serious 1/30/2011 81 Female 117 lb 6/8/2011 Physician United Kingdom
Primary
Concomitant
Tachycardia Hospitalization 82 Male 5/26/2011 Lawyer United States
Primary
Concomitant
Oesophagitis Hospitalization 7/23/2009 70 Female 6/17/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dysgeusia 10/1/2011 81 Male 145 lb 10/21/2011 Consumer United States
Primary
Concomitant
Drug Ineffective 10/1/2011 81 Male 145 lb 11/29/2011 Consumer United States
Primary
Concomitant
Drug Ineffective 10/1/2011 81 Male 145 lb 12/12/2011 Consumer United States
Primary
Concomitant
Muscular Weakness Disability 70 Male 185 lb 6/25/2012 Consumer United States
Primary
Concomitant
Glaucoma Other Serious 84 Male 7/2/2012 Consumer United States
Primary
Concomitant
Chest X-ray Abnormal Other Serious 61 Female 160 lb 7/2/2012 Consumer United States
Primary
Concomitant
Condition Aggravated Other Serious 84 Male 7/3/2012 Consumer United States
Primary
Concomitant
Back Pain Male 7/10/2012 Consumer United States
Primary
Concomitant
Myopathy Hospitalization 80 Male 7/19/2012 Other Health Professional Italy
Primary
Concomitant
Interacting
Glaucoma Other Serious 84 Male 146 lb 7/25/2012 Consumer United States
Primary
Concomitant
Blood Glucose Increased Male 282 lb 8/3/2012 Consumer United States
Primary
Concomitant
Arthralgia Other Serious 1/1/2011 83 Male 209 lb 8/6/2012 Physician Japan
Primary
Concomitant
Ocular Hyperaemia Other Serious 84 Male 146 lb 8/10/2012 Physician United States
Primary
Concomitant
Anaphylactic Reaction Other Serious Female 8/23/2012 Consumer United States
Primary
Concomitant

Drug Data