Isosorbide combined with Toprol-XL

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Prostate Cancer Hospitalization 12/29/2000 59 Male 245 lb 1/9/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 5/20/2002 58 Male 154 lb 1/17/2006 Lawyer United States
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 3/4/2003 66 Female 238 lb 1/17/2006 Physician United States
Primary
Concomitant
Tenderness Hospitalization 10/7/2005 75 Female 130 lb 1/6/2006 Other Health Professional United States
Primary
Concomitant
Meniscus Lesion Hospitalization 5/18/2002 58 Male 154 lb 1/20/2006 Physician United States
Primary
Concomitant
Staphylococcal Infection Life Threatening 58 Male 2/15/2006 Consumer United States
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 3/4/2003 66 Female 238 lb 2/21/2006 Physician United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 2/1/2001 54 Female 238 lb 2/23/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 8/1/2001 81 Female 143 lb 3/2/2006 Physician United States
Primary
Concomitant
Ischaemic Stroke Hospitalization 3/20/2003 53 Female 157 lb 3/7/2006 Physician United States
Primary
Concomitant
Sepsis Hospitalization 2/23/2006 Male 188 lb 2/24/2006 Other Health Professional United States
Primary
Concomitant
Vomiting 64 Male 3/7/2006 Consumer United States
Primary
Concomitant
Vomiting 64 Male 3/7/2006 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 3/1/2002 65 Male 3/8/2006 Physician United States
Primary
Concomitant
Ischaemic Stroke Hospitalization 3/20/2003 53 Female 157 lb 3/10/2006 Physician United States
Primary
Concomitant
Ischaemic Stroke Hospitalization 3/20/2003 53 Female 157 lb 3/16/2006 Physician United States
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 3/4/2003 66 Female 238 lb 3/22/2006 Physician United States
Primary
Concomitant
Wheezing Hospitalization 2/23/2006 67 Male 188 lb 3/20/2006 Physician United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 5/28/2001 81 Female 146 lb 3/29/2006 Lawyer United States
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 3/4/2003 66 Female 238 lb 3/29/2006 Physician United States
Primary
Concomitant
Prostate Cancer Hospitalization 12/29/2000 59 Male 245 lb 3/30/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2002 Male 390 lb 4/3/2006 Lawyer United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 1/1/1999 54 Female 238 lb 4/3/2006 Physician United States
Primary
Secondary
Concomitant
Vertebral Injury Other Serious 1/1/2002 Male 390 lb 4/4/2006 Lawyer United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 5/28/2001 81 Female 146 lb 4/4/2006 Physician United States
Primary
Concomitant
Nausea Hospitalization 1/1/2003 56 Female 300 lb 4/4/2006 Lawyer United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 3/27/2002 65 Male 231 lb 4/5/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization Female 183 lb 4/5/2006 Consumer United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 1/27/2003 44 Female 205 lb 4/6/2006 Lawyer United States
Primary
Concomitant
Nausea Hospitalization 1/1/2003 56 Female 300 lb 4/13/2006 Lawyer United States
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 4/11/2006 88 Female 77 lb 4/11/2006 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Hypokinesia Hospitalization 7/30/2003 66 Female 238 lb 4/13/2006 Physician United States
Primary
Concomitant
Somnolence Hospitalization 3/20/2003 53 Female 157 lb 4/14/2006 Physician United States
Primary
Concomitant
Syncope Hospitalization 12/1/1999 Male 280 lb 4/17/2006 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 2/23/2006 67 Male 188 lb 4/7/2006 Physician United States
Primary
Secondary
Concomitant
Heart Rate Decreased Required Intervention 1/1/2000 83 Male 4/11/2006 United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 1/16/2003 53 Female 157 lb 4/24/2006 Physician United States
Primary
Concomitant
Pharmaceutical Product Complaint Hospitalization Female 183 lb 4/26/2006 Consumer United States
Primary
Secondary
Concomitant
Vascular Occlusion Hospitalization 2/1/2004 63 Male 243 lb 4/28/2006 Physician United States
Primary
Concomitant
Neoplasm Malignant Hospitalization 3/22/2003 27 Female 212 lb 5/1/2006 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 4/26/2001 75 Female 150 lb 5/1/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 Male 150 lb 4/25/2006 United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 2/23/2006 67 Male 188 lb 4/28/2006 Physician United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious Female 139 lb 3/2/2006 United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 2/1/2002 76 Male 196 lb 5/9/2006 Lawyer United States
Primary
Concomitant
Vision Blurred Hospitalization 1/16/2003 53 Female 157 lb 5/9/2006 Physician United States
Primary
Concomitant
Syncope Hospitalization 11/1/2005 79 Female 5/10/2006 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization Female 183 lb 5/10/2006 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 1/1/2002 48 Male 201 lb 5/12/2006 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 4/26/2001 75 Female 150 lb 5/17/2006 Physician United States
Primary
Concomitant
Pain Of Skin 2/8/2006 62 Male 4/24/2006 United States
Primary
Concomitant
Respiratory Failure Other Serious 2/5/2004 70 Female 6/26/2006 United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 3/20/2006 59 Female 223 lb 5/23/2006 Physician United States
Primary
Concomitant
Pruritus 4/4/2006 58 Female 238 lb 6/30/2006 Consumer United States
Primary
Concomitant
Thirst Other Serious 6/25/2006 69 Male 7/10/2006 Consumer United States
Primary
Concomitant
Psychotic Disorder Other Serious 74 Female 7/13/2006 Consumer United States
Primary
Secondary
Concomitant
Jugular Vein Thrombosis Other Serious 4/9/2006 62 Female 138 lb 9/18/2006 United States
Primary
Concomitant
Somnolence 3/1/2006 96 Female 7/31/2006 Consumer United States
Primary
Concomitant
Thirst Other Serious 6/25/2006 69 Male 10/24/2006 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Hospitalization 4/1/2006 Female 10/30/2006 Physician United States
Primary
Concomitant
Blood Pressure Increased 10/25/2005 56 Female 10/30/2006 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 6/22/2006 75 Female 10/30/2006 Consumer United States
Primary
Concomitant
Thrombocytopenia Life Threatening 12/1/2005 83 Male 185 lb 11/7/2006 Physician United States
Primary
Concomitant
Sinusitis Other Serious 12/1/2005 Male 12/5/2006 Consumer United States
Primary
Concomitant
Initial Insomnia 7/6/2006 45 Male 148 lb 10/11/2006 Consumer United States
Primary
Concomitant
Thirst Other Serious 6/25/2006 69 Male 1/8/2007 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Hospitalization Female 183 lb 1/26/2007 Consumer United States
Primary
Secondary
Concomitant
Myalgia Other Serious 11/1/2004 65 Female 6/14/2005 United States
Primary
Concomitant
Groin Pain Other Serious 48 Male 210 lb 11/17/2005 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2001 41 Female 245 lb 3/5/2007 Consumer United States
Primary
Concomitant
Insomnia Male 3/7/2007 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Hospitalization 10/1/2006 82 3/19/2007 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2001 41 Female 245 lb 3/21/2007 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 81 Female 170 lb 11/28/2006 United States
Primary
Concomitant
Hypersomnia 10/19/2006 53 Female 205 lb 1/12/2007 Consumer United States
Primary
Concomitant
Therapeutic Response Unexpected 3/1/2006 62 Male 4/27/2007 Consumer United States
Primary
Secondary
Concomitant
Intraocular Pressure Increased Other Serious 2/3/2007 Female 5/1/2007 Consumer United States
Primary
Secondary
Concomitant
Cerebral Haemorrhage Required Intervention 5/6/2007 Female 270 lb 5/18/2007 Pharmacist United States
Primary
Concomitant
Refusal Of Treatment By Patient Other Serious 10/1/2003 Female 6/4/2007 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 6/1/2007 88 Female 119 lb 8/31/2007 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Death 5/21/2008 79 Female 243 lb 8/20/2008 Consumer United States
Primary
Concomitant
Pain Other Serious 1/1/2006 Male 241 lb 8/26/2008 Consumer United States
Primary
Concomitant
Myocardial Ischaemia Hospitalization 55 Male 230 lb 8/27/2008 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 4/1/2008 59 Male 351 lb 8/29/2008 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 4/1/2008 59 Male 351 lb 9/18/2008 Consumer United States
Primary
Concomitant
Encephalopathy Hospitalization 8/7/2008 Female 10/3/2008 United States
Primary
Secondary
Concomitant
Death Death 9/29/2008 50 Male 10/13/2008 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 9/29/2008 Male 10/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 84 Male 10/28/2008 Consumer United States
Primary
Concomitant
Encephalopathy Hospitalization 8/7/2008 Female 10/31/2008 United States
Primary
Secondary
Concomitant
Visual Impairment Hospitalization 86 Female 10/29/2008 United States
Primary
Concomitant
Weight Decreased Other Serious 9/11/2003 47 Female 260 lb 11/10/2008 United States
Primary
Concomitant
Pain Other Serious 1/1/2006 Male 241 lb 11/17/2008 Consumer United States
Primary
Concomitant
Encephalopathy Hospitalization 8/7/2008 Female 286 lb 11/18/2008 United States
Primary
Secondary
Concomitant
Drug Ineffective 1/28/2008 55 Male 11/14/2008 United States
Primary
Concomitant
Muscle Spasms 79 Male 220 lb 12/17/2008 United States
Primary
Concomitant
Encephalopathy Hospitalization 7/7/2008 Female 286 lb 12/22/2008 Physician United States
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2006 Male 241 lb 12/22/2008 Consumer United States
Primary
Concomitant
Encephalopathy Hospitalization 7/7/2008 Female 286 lb 1/5/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/29/2008 84 Male 159 lb 1/26/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 9/29/2008 84 Male 159 lb 2/23/2009 Physician United States
Primary
Concomitant
Multiple Injuries Death 67 Male 3/12/2009 United States
Primary
Concomitant
Tardive Dyskinesia Other Serious 8/10/2000 57 Male 344 lb 4/3/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Chronic Death 27 Male 4/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 4/1/2009 Female 146 lb 4/8/2009 Physician United States
Primary
Concomitant
Renal Failure Chronic Death 27 Male 4/9/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Swelling Face Hospitalization 3/28/2009 63 Female 4/9/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 2/1/2006 57 Male 4/13/2009 Lawyer United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 4/19/2006 67 Male 180 lb 5/1/2009 United States
Primary
Concomitant
Pyrexia Hospitalization 3/1/2009 59 Male 5/14/2009 Other Health Professional United States
Primary
Concomitant
Erythema 5/6/2009 82 Female 185 lb 6/3/2009 Consumer United States
Primary
Concomitant
Purple Glove Syndrome Hospitalization 11/3/2008 78 Female 161 lb 6/4/2009 Pharmacist United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 6/5/2009 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 5/1/2008 79 Female 4/6/2009 Consumer United States
Primary
Concomitant
Hot Flush 80 Female 132 lb 6/17/2009 United States
Primary
Concomitant
Erythema 5/6/2009 82 Female 185 lb 7/15/2009 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/17/2007 57 Male 7/22/2009 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 1/17/2007 57 Male 7/31/2009 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 1/17/2007 57 Male 8/4/2009 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 3/18/2008 56 Female 258 lb 7/22/2009 United States
Primary
Concomitant
Vomiting Hospitalization 85 Female 8/3/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 3/18/2008 56 Female 258 lb 8/6/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 10/25/2007 73 Male 229 lb 8/4/2009 United States
Primary
Concomitant
Vomiting Hospitalization 7/1/2007 48 Male 456 lb 9/1/2009 United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/17/2007 57 Male 9/8/2009 Consumer United States
Primary
Secondary
Concomitant
Unevaluable Event Death 68 Male 9/1/2009 Lawyer United States
Primary
Concomitant
Thyroxine Free Increased Other Serious 4/23/2007 54 Female 258 lb 9/2/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 7/1/2007 48 Male 456 lb 9/4/2009 United States
Primary
Concomitant
Weight Increased Other Serious 4/23/2007 54 Female 258 lb 9/3/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 9/3/2009 United States
Primary
Concomitant
Ureteric Cancer Hospitalization 66 Male 9/8/2009 United States
Primary
Concomitant
Tinnitus 6/30/2009 Male 168 lb 9/17/2009 Physician
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 9/15/2009 United States
Primary
Concomitant
Vitreous Haemorrhage Hospitalization 2/20/2008 65 Female 180 lb 9/15/2009 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 3/1/2007 60 Female 9/23/2009 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Hospitalization 7/26/2009 70 Female 239 lb 9/17/2009 Pharmacist United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 9/17/2009 Consumer United States
Primary
Concomitant
Respiratory Disorder Death 68 Male 9/18/2009 United States
Primary
Concomitant
Renal Disorder Other Serious 1/1/2009 159 lb 10/2/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 9/23/2009 United States
Primary
Concomitant
Vomiting Hospitalization 2/20/2008 62 Female 180 lb 9/28/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 10/25/2007 68 Male 229 lb 9/24/2009 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 4/23/2007 54 Female 258 lb 9/24/2009 United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/17/2007 57 Male 10/7/2009 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 1/17/2007 57 Male 10/7/2009 Consumer United States
Primary
Secondary
Concomitant
Ketoacidosis Hospitalization 11/1/2002 65 Male 200 lb 10/13/2009 Physician United States
Primary
Concomitant
Ill-defined Disorder Disability Female 215 lb 10/16/2009 Other Health Professional United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 10/10/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 10/16/2009 Lawyer United States
Primary
Concomitant
Wheezing Hospitalization 66 Male 10/17/2009 United States
Primary
Concomitant

Drug Data