Isosorbide combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Myocardial Infarction Hospitalization 1/1/2001 69 Female 126 lb 1/19/2006 Lawyer United States
Primary
Concomitant
Hypertension Hospitalization 1/16/2006 Female 1/31/2006 Physician United States
Primary
Concomitant
Supraventricular Extrasystoles Hospitalization 7/31/2000 49 Male 4/24/2006 Lawyer United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 7/31/2000 49 Male 5/8/2006 Physician United States
Primary
Concomitant
Wound Infection Hospitalization 12/20/2000 58 Female 192 lb 5/8/2006 Physician United States
Primary
Concomitant
Throat Irritation Hospitalization Male 5/24/2006 Consumer United States
Primary
Concomitant
Tremor 3/17/2006 67 Male 5/30/2006 Consumer United States
Primary
Concomitant
Nervousness 6/1/2005 69 Female 139 lb 6/8/2006 Consumer United States
Primary
Concomitant
Coronary Artery Stenosis Hospitalization 6/22/2006 47 Male 203 lb 9/20/2006 United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 9/28/2006 82 Male Pharmacist United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Other Serious 75 Female 133 lb 10/10/2006 Pharmacist United States
Primary
Concomitant
Haematuria Hospitalization 10/3/2006 Male 165 lb 10/31/2006 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 10/1/2005 52 Male 11/13/2006 Consumer United States
Primary
Concomitant
Tremor Required Intervention 5/2/2006 65 Female 11/13/2006 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Hospitalization 10/1/2006 82 3/19/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious 3/1/2007 56 Female 207 lb 5/7/2007 United States
Primary
Concomitant
Headache 66 Male 8/15/2008 Consumer United States
Primary
Concomitant
Myositis Hospitalization 10/3/2006 70 Male 9/16/2008 Physician United States
Primary
Concomitant
Death Death 8/1/2008 Female 201 lb 9/23/2008 Physician United States
Primary
Concomitant
Urinary Tract Infection Required Intervention 5/3/2008 57 Male 197 lb 7/17/2008 Consumer United States
Primary
Concomitant
Ulcer Haemorrhage Other Serious 1/1/2008 78 Female 10/31/2008 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 75 Male 205 lb 10/29/2008 United States
Primary
Concomitant
Nausea Hospitalization 1/1/2007 Male 232 lb 11/20/2008 Consumer United States
Primary
Concomitant
Stent Placement Hospitalization 67 Male 12/2/2008 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Death 9/6/2008 Male 12/17/2008 Physician United States
Primary
Concomitant
Hyperkalaemia Hospitalization 75 Female 12/18/2008 Other Health Professional Poland
Primary
Secondary
Stent Placement Hospitalization 10/26/2008 67 Male 12/22/2008 Consumer United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Death 1/1/1996 45 Male 4/2/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 54 Male 4/2/2009 United States
Primary
Concomitant
Oral Herpes Other Serious 2/1/2008 Male 4/10/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 76 Male 5/26/2009 Lawyer United States
Primary
Concomitant
Erythema 5/6/2009 82 Female 185 lb 6/3/2009 Consumer United States
Primary
Concomitant
Muscle Spasms 85 Female 6/19/2009 Consumer United States
Primary
Concomitant
Wheezing Hospitalization 77 Male 6/18/2009 United States
Primary
Concomitant
Renal Function Test Abnormal Disability 1/1/2006 Male 7/6/2009 Consumer United States
Primary
Concomitant
Oropharyngeal Discomfort 1/1/2009 67 Male 6/25/2009 Consumer United States
Primary
Secondary
Concomitant
Erythema 5/6/2009 82 Female 185 lb 7/15/2009 Consumer United States
Primary
Concomitant
Unevaluable Event Death 65 Female 155 lb 7/10/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 76 Male 7/22/2009 Lawyer United States
Primary
Concomitant
Respiratory Failure Hospitalization 80 Female 8/3/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 51 Female 8/3/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 8/4/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 10/25/2007 73 Male 229 lb 8/4/2009 United States
Primary
Concomitant
Visual Impairment Other Serious 2/1/2008 Male 8/17/2009 Consumer United States
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 77 Male 8/25/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Death 73 Female 8/28/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 65 Female 155 lb 8/24/2009 United States
Primary
Concomitant
Vomiting Hospitalization 7/1/2007 48 Male 456 lb 9/1/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 76 Male 9/1/2009 Lawyer United States
Primary
Concomitant
Unevaluable Event Hospitalization 90 Female 9/2/2009 United States
Primary
Concomitant
Vitamin B12 Decreased Hospitalization 80 Female 9/3/2009 United States
Primary
Concomitant
Urosepsis Death 91 Female 9/4/2009 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 7/1/2007 48 Male 456 lb 9/4/2009 United States
Primary
Concomitant
Surgery Hospitalization 90 Female 9/4/2009 Lawyer United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 5/27/2005 58 Male 195 lb 9/4/2009 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 76 Male 9/4/2009 Lawyer United States
Primary
Concomitant
Stent Placement Hospitalization 10/26/2008 67 Male 9/14/2009 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 82 Female 9/10/2009 United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 9/7/2008 53 Male 243 lb 9/14/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 76 Male 9/15/2009 United States
Primary
Concomitant
Renal Failure Hospitalization Female 9/16/2009 United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 90 Female 9/16/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 9/17/2009 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 64 Female 155 lb 9/17/2009 United States
Primary
Concomitant
Wheezing Hospitalization 78 Male 9/21/2009 United States
Primary
Concomitant
Vomiting Other Serious 4/17/2009 Male 168 lb 10/2/2009 United States
Primary
Secondary
Concomitant
Vomiting Death 86 Female 9/23/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 9/23/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 64 Female 155 lb 9/24/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 51 Female 9/25/2009 United States
Primary
Concomitant
Spinal Column Stenosis Hospitalization 9/7/2008 53 Male 9/28/2009 United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 5/27/2005 58 Male 195 lb 9/28/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 10/25/2007 68 Male 229 lb 9/24/2009 United States
Primary
Concomitant
Malaise Female 155 lb 10/12/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 5/14/2002 60 Female 210 lb 10/15/2009 United States
Primary
Concomitant
Pain In Extremity Hospitalization 10/7/2009 Male 208 lb 10/12/2009 Other Health Professional United States
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 64 Female 10/12/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 10/10/2009 United States
Primary
Concomitant
Vitamin B12 Decreased Hospitalization 80 Female 10/9/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 51 Female 10/9/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 9/7/2008 53 Male 243 lb 10/9/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 10/16/2009 Lawyer United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 5/27/2005 58 Male 195 lb 10/17/2009 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 64 Female 10/26/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 90 Female 10/26/2009 United States
Primary
Concomitant
Wheezing Hospitalization 9/7/2008 53 Male 243 lb 10/27/2009 United States
Primary
Concomitant
Paralysis Hospitalization 10/27/2009 84 Male 212 lb 11/9/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 72 Male 11/4/2009 United States
Primary
Concomitant
Paraesthesia Hospitalization 5/27/2005 58 Male 195 lb 11/4/2009 United States
Primary
Concomitant
Weight Decreased Death 73 Female 11/5/2009 United States
Primary
Concomitant
Drug Ineffective 10/1/2008 67 Male 11/11/2009 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 90 Female 11/18/2009 United States
Primary
Concomitant
Photodermatosis Hospitalization 72 Male 11/18/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 5/14/2002 60 Female 210 lb 11/26/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 46 Female 11/18/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 63 Female 11/18/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 64 Female 155 lb 11/20/2009 United States
Primary
Concomitant
Injection Site Haematoma Hospitalization 1/1/2005 Male 280 lb 12/1/2009 Consumer United States
Primary
Concomitant
Wound Secretion Hospitalization Male 12/1/2009 Lawyer United States
Primary
Concomitant
Photodermatosis Hospitalization 72 Male 12/1/2009 United States
Primary
Concomitant
Urinary Retention Hospitalization 61 Male 12/10/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 79 Male 12/11/2009 United States
Primary
Concomitant
Photodermatosis Hospitalization 57 Male 12/10/2009 United States
Primary
Concomitant
Medication Error 10/21/2009 69 Female 184 lb 12/22/2009 Consumer United States
Primary
Concomitant
Joint Swelling 91 Female 126 lb 12/22/2009 Consumer United States
Primary
Concomitant
Tremor Other Serious 12/1/2009 Male 12/23/2009 Consumer United States
Primary
Concomitant
Urinary Retention Hospitalization 61 Male 12/23/2009 Lawyer United States
Primary
Concomitant
Skin Ulcer Other Serious 9/1/2006 79 Male 152 lb 1/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Unevaluable Event Death 74 Male 179 lb 1/13/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 61 Male 236 lb 1/11/2010 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 55 Female 1/13/2010 Consumer United States
Primary
Concomitant
Skin Ulcer Other Serious 9/1/2006 79 Male 152 lb 1/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 79 Male 1/23/2010 Lawyer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 9/8/2009 Male 1/22/2010 Other Health Professional United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 72 Male 256 lb 2/5/2010 United States
Primary
Concomitant
Weight Increased Hospitalization Male 2/5/2010 Lawyer United States
Primary
Concomitant
Weight Increased Hospitalization Male 2/5/2010 Lawyer United States
Primary
Concomitant
Waist Circumference Increased Hospitalization 72 Male 256 lb 2/5/2010 United States
Primary
Concomitant
Hepatic Cirrhosis Other Serious 2/22/2010 Male 3/1/2010 Consumer
Primary
Concomitant
Urinary Retention Other Serious 60 Male 236 lb 4/22/2010 Consumer United States
Primary
Secondary
Concomitant
Vitamin B12 Decreased Hospitalization 80 Female 5/6/2010 United States
Primary
Concomitant
Cardiac Failure Hospitalization 5/19/2010 82 Male 147 lb 6/8/2010 Physician United States
Primary
Concomitant
Vertebrobasilar Insufficiency Other Serious 80 Male 150 lb 6/4/2010 United States
Primary
Concomitant
Cardiac Failure Hospitalization 5/19/2010 82 Male 147 lb 6/22/2010 Physician United States
Primary
Concomitant
Drug Ineffective Male 6/29/2010 Other Health Professional United States
Primary
Concomitant
Cardiac Failure Hospitalization 5/19/2010 82 Male 147 lb 6/30/2010 Physician United States
Primary
Concomitant
Liver Function Test Abnormal Hospitalization Female 7/1/2010 Physician United States
Primary
Concomitant
Skin Ulcer Other Serious 9/1/2006 79 Male 152 lb 7/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Hospitalization 55 Female 6/25/2010 United States
Primary
Concomitant
Liver Function Test Abnormal Hospitalization Female 7/7/2010 Physician United States
Primary
Concomitant
Nausea 5/1/2007 52 Male 301 lb 7/13/2010 Consumer United States
Primary
Concomitant
Respiratory Tract Irritation 67 Male 7/14/2010 Consumer United States
Primary
Secondary
Concomitant
Nausea 9/18/2007 63 Male 360 lb 7/15/2010 Consumer United States
Primary
Secondary
Concomitant
Lung Disorder Other Serious 9/1/2007 75 Male 235 lb 7/16/2010 Other Health Professional United States
Primary
Concomitant
Skin Ulcer Other Serious 9/1/2006 79 Male 152 lb 7/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 86 Female 7/26/2010 United States
Primary
Concomitant
Skin Ulcer Other Serious 9/1/2006 79 Male 152 lb 8/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 9/1/2006 79 Male 152 lb 8/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Palpitations 6/20/2010 75 Female 205 lb 8/29/2010 Consumer United States
Primary
Concomitant
Pharyngeal Oedema Other Serious 3/1/2008 50 Male 328 lb 9/15/2010 Physician United States
Primary
Concomitant
Oropharyngeal Pain 8/12/2010 80 Female 9/23/2010 Consumer
Primary
Concomitant
Malaise Female 155 lb 10/13/2010 United States
Primary
Concomitant
Vision Blurred Hospitalization 1/1/2009 81 Female 10/14/2010 Consumer
Primary
Concomitant
Vision Blurred Hospitalization 1/1/2009 81 Female 10/20/2010 Consumer
Primary
Concomitant
Drug Ineffective Hospitalization 5/1/2011 79 Male 6/3/2011 Pharmacist United States
Primary
Concomitant
Dyspnoea 69 Male 6/21/2011 Consumer United States
Primary
Concomitant
Chest Pain Hospitalization 5/1/2011 79 Male 9/21/2011 Pharmacist United States
Primary
Concomitant
Upper Limb Fracture Hospitalization 10/1/2011 74 Female 165 lb 1/18/2012 Consumer United States
Primary
Concomitant
Insomnia Other Serious 1/1/2012 61 Male 229 lb 6/5/2012 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 3/1/2010 78 Female 171 lb 11/9/2010 Other Health Professional United States
Primary
Concomitant

Drug Data