Isosorbide combined with Spiriva

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Cardiac Arrest Death 12/19/2005 83 Male 1/5/2006 Physician
Primary
Concomitant
Ventricular Hypertrophy Other Serious 12/19/2005 83 Male 2/1/2006 Physician
Primary
Concomitant
Ventricular Hypertrophy Other Serious 2/1/2001 54 Female 238 lb 2/23/2006 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 2/23/2006 Male 188 lb 2/24/2006 Other Health Professional United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 2/25/2006 Male 88 lb 3/16/2006 Consumer United States
Primary
Concomitant
Wheezing Hospitalization 2/23/2006 67 Male 188 lb 3/20/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Other Serious 1/1/1999 54 Female 238 lb 4/3/2006 Physician United States
Primary
Secondary
Concomitant
Tooth Disorder Other Serious 3/1/2006 Female 180 lb 4/6/2006 Consumer United States
Primary
Secondary
Concomitant
Respiratory Disorder Other Serious 75 Female 180 lb 4/7/2006 United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/23/2006 67 Male 188 lb 4/7/2006 Physician United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 2/23/2006 67 Male 188 lb 4/28/2006 Physician United States
Primary
Secondary
Concomitant
Throat Irritation Hospitalization Male 5/24/2006 Consumer United States
Primary
Concomitant
High Density Lipoprotein Decreased Other Serious 3/1/2006 Female 180 lb 7/10/2006 Consumer United States
Primary
Secondary
Concomitant
Condition Aggravated Hospitalization 2/25/2006 Male 88 lb 11/8/2006 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Hospitalization 10/5/2006 82 Male 11/24/2006 Consumer United States
Primary
Concomitant
Myocardial Ischaemia Other Serious 10/1/2006 82 Male 2/12/2007 Consumer United States
Primary
Concomitant
Toothache Other Serious 12/30/2006 Female 180 lb 3/26/2007 Consumer United States
Primary
Concomitant
Toothache Other Serious 12/30/2006 Female 180 lb 5/4/2007 Consumer United States
Primary
Concomitant
Macular Degeneration Other Serious 1/1/2008 93 Male 8/20/2008 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Hospitalization 1/27/2008 Female 9/29/2008 Consumer
Primary
Concomitant
Fatigue 10/1/2008 75 Male 11/10/2008 Consumer
Primary
Concomitant
Chest Discomfort Hospitalization 1/27/2008 Female 11/11/2008 Consumer
Primary
Concomitant
Hypertension Hospitalization 4/1/2007 Female 11/20/2008 Consumer
Primary
Concomitant
Hospitalisation Hospitalization 1/27/2008 Female 12/5/2008 Consumer
Primary
Concomitant
Hypertension Hospitalization 4/1/2007 Female 12/18/2008 Consumer
Primary
Concomitant
Fatigue 10/1/2008 75 Male 3/5/2009 Consumer
Primary
Concomitant
Sinus Disorder Life Threatening 2/1/2008 Female 3/6/2009 Consumer
Primary
Secondary
Concomitant
Hypertension Hospitalization 4/1/2007 Female 3/25/2009 Consumer
Primary
Concomitant
Sinus Disorder Life Threatening 2/1/2008 Female 3/30/2009 Physician
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Death 1/1/1996 45 Male 4/2/2009 United States
Primary
Concomitant
Varicose Vein Ruptured Hospitalization 1/1/2007 Female 4/13/2009 Consumer
Primary
Concomitant
Visual Impairment 4/1/2008 Female 5/8/2009 Consumer
Primary
Secondary
Concomitant
Productive Cough 5/6/2009 Male 5/13/2009 Consumer
Primary
Concomitant
Productive Cough 5/6/2009 Male 5/22/2009 Consumer
Primary
Concomitant
Product Quality Issue 4/13/2008 65 Female 5/29/2009 Consumer United States
Primary
Concomitant
Sinus Disorder Life Threatening 2/1/2008 Female 6/12/2009 Physician
Primary
Secondary
Concomitant
Sinusitis 5/6/2009 Male 6/17/2009 Consumer
Primary
Concomitant
Visual Impairment 4/1/2008 Female 6/26/2009 Consumer
Primary
Secondary
Concomitant
Renal Neoplasm Hospitalization Female 7/1/2009 Consumer
Primary
Concomitant
Dyspnoea 6/7/2009 76 Female 7/7/2009 Consumer
Primary
Concomitant
Pulmonary Embolism Hospitalization 7/1/2007 76 Female 7/9/2009 Consumer
Primary
Concomitant
Renal Neoplasm Hospitalization 5/1/2009 Female 180 lb 7/20/2009 Physician
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/25/2007 73 Male 229 lb 8/4/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 50 Male 8/31/2009 United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 68 Female 160 lb 8/31/2009 United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 50 Male 9/4/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 76 Male 9/4/2009 Lawyer United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 50 Male 9/10/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 9/15/2009 United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 9/7/2008 53 Male 243 lb 9/14/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 76 Male 9/15/2009 United States
Primary
Concomitant
Wheezing Hospitalization 78 Male 9/21/2009 United States
Primary
Concomitant
Spinal Column Stenosis Hospitalization 9/7/2008 53 Male 9/28/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 10/25/2007 68 Male 229 lb 9/24/2009 United States
Primary
Concomitant
Neuropathy Peripheral 1/1/2007 Female 10/6/2009 Consumer
Primary
Concomitant
Weight Increased Hospitalization 9/7/2008 53 Male 243 lb 10/9/2009 United States
Primary
Concomitant
Neuropathy Peripheral 1/1/2007 Female 10/29/2009 Consumer
Primary
Concomitant
Vomiting Other Serious 78 Female 10/27/2009 Lawyer United States
Primary
Concomitant
Wheezing Hospitalization 9/7/2008 53 Male 243 lb 10/27/2009 United States
Primary
Concomitant
Death Death 11/5/2009 Male 11/19/2009 Consumer United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 50 Male 11/18/2009 United States
Primary
Concomitant
Death Death 11/5/2009 Male 12/3/2009 Physician United States
Primary
Concomitant
Injection Site Haematoma Hospitalization 1/1/2005 Male 280 lb 12/1/2009 Consumer United States
Primary
Concomitant
Urinary Retention Hospitalization 61 Male 12/1/2009 United States
Primary
Concomitant
Transplant Failure Hospitalization Female 12/11/2009 Physician United States
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 61 Male 12/10/2009 United States
Primary
Concomitant
Dyspnoea Other Serious 11/8/2009 62 Male 173 lb 12/23/2009 United States
Primary
Concomitant
Urinary Retention Hospitalization 61 Male 12/23/2009 Lawyer United States
Primary
Concomitant
Speech Disorder Life Threatening 10/1/2008 Female 12/31/2009 Consumer
Primary
Concomitant
Hypoacusis 12/31/2009 Male 1/11/2010 Consumer
Primary
Concomitant
Weight Decreased Other Serious 61 Male 236 lb 1/11/2010 United States
Primary
Concomitant
Ageusia 1/7/2010 90 Female 190 lb 1/26/2010 United States
Primary
Concomitant
Vomiting Other Serious 11/11/2005 Female 2/3/2010 Physician United States
Primary
Concomitant
Pneumonia Other Serious 10/1/2009 62 Male 173 lb 2/4/2010 United States
Primary
Concomitant
Vomiting Other Serious 78 Female 1/22/2010 United States
Primary
Concomitant
Ageusia Other Serious 1/7/2010 50 Male 150 lb 2/22/2010 United States
Primary
Secondary
Concomitant
Hepatic Cirrhosis Other Serious 2/22/2010 Male 3/1/2010 Consumer
Primary
Concomitant
Prostatic Specific Antigen Increased 2/18/2010 Male 3/2/2010 Consumer
Primary
Concomitant
Thoracic Vertebral Fracture Hospitalization 65 Female 160 lb 2/22/2010 United States
Primary
Concomitant
Urinary Retention Other Serious 60 Male 236 lb 4/22/2010 Consumer United States
Primary
Secondary
Concomitant
Dyspnoea Other Serious 1/1/2009 65 Female 6/7/2010 Consumer United States
Primary
Concomitant
Death Death 1/26/2010 65 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Dyspnoea Other Serious 1/1/2009 65 Female 7/7/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 6/25/2008 79 Male 7/8/2010 Lawyer United States
Primary
Concomitant
Pain 12/5/2006 74 Female 110 lb 7/8/2010 Consumer United States
Primary
Concomitant
Tinnitus Male 256 lb 7/8/2010 Consumer United States
Primary
Concomitant
Weight Decreased 4/1/2007 55 Female 187 lb 7/13/2010 Other Health Professional United States
Primary
Concomitant
Nausea 7/1/2007 67 Female 160 lb 7/14/2010 Consumer United States
Primary
Concomitant
Insomnia 5/1/2007 56 Male 7/14/2010 Consumer United States
Primary
Concomitant
Muscle Spasms 6/22/2010 78 Male 7/20/2010 Consumer
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious Female 7/21/2010 Consumer United States
Primary
Concomitant
Renal Cyst Life Threatening 61 Female 7/22/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious Male 192 lb 7/30/2010 Consumer United States
Primary
Concomitant
Wheezing Other Serious 74 Female 8/4/2010 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 75 Female 7/26/2010 Consumer United States
Primary
Concomitant
Tachycardia Death 7/23/2010 65 Male 8/9/2010 Physician United States
Primary
Concomitant
Wheezing Other Serious 74 Female 8/26/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/1/2004 75 Male 184 lb 8/27/2010 United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious Female 8/27/2010 Consumer United States
Primary
Concomitant
Pruritus 1/1/2007 Male 8/27/2010 United States
Primary
Concomitant
Vomiting Other Serious 6/25/2008 79 Male 9/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 1/1/2008 88 Male 9/8/2010 Consumer
Primary
Concomitant
Death Death Male 238 lb 9/9/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 6/1/2004 75 Male 184 lb 9/20/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/1/2004 75 Male 184 lb 10/1/2010 United States
Primary
Secondary
Concomitant
Productive Cough Other Serious 1/1/2008 88 Male 10/4/2010 Consumer
Primary
Concomitant
Wheezing Other Serious 74 Female 10/5/2010 Consumer United States
Primary
Secondary
Concomitant
Coronary Artery Disease Death Male 238 lb 10/12/2010 Other Health Professional United States
Primary
Concomitant
Fluid Imbalance 73 Female 250 lb 10/13/2010 Consumer United States
Primary
Concomitant
Transplant Failure Hospitalization Female 273 lb 10/14/2010 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 1/1/2009 81 Female 10/14/2010 Consumer
Primary
Concomitant
Therapeutic Response Decreased Other Serious Female 10/20/2010 Consumer United States
Primary
Concomitant
Vision Blurred Hospitalization 1/1/2009 81 Female 10/20/2010 Consumer
Primary
Concomitant
Weight Decreased Other Serious Male 192 lb 10/29/2010 Other Health Professional United States
Primary
Concomitant
Pollakiuria Other Serious 10/28/2010 67 Female 169 lb 11/2/2010 Consumer United States
Primary
Concomitant
Death Other Serious Female 254 lb 2/23/2011 Other Health Professional United States
Primary
Concomitant
Leukoplakia Other Serious 1/1/2010 67 Male 192 lb 2/24/2011 Consumer United States
Primary
Concomitant
Leukoplakia Other Serious 1/1/2010 67 Male 192 lb 3/3/2011 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 5/10/2011 74 Female 5/31/2011 Pharmacist United States
Primary
Concomitant
Peripheral Ischaemia Hospitalization 1/1/2011 74 Female 6/7/2011 Physician United States
Primary
Concomitant
Vascular Graft Occlusion Disability 1/1/2011 73 Female 6/14/2011 Physician United States
Primary
Concomitant
Dyspnoea 69 Male 6/21/2011 Consumer United States
Primary
Concomitant
Rash Hospitalization 6/1/2011 72 Male 209 lb 7/8/2011 Physician United States
Primary
Secondary
Concomitant
Insomnia Other Serious 9/1/2011 47 Male 204 lb 9/9/2011 Consumer United States
Primary
Concomitant
Insomnia Other Serious 9/1/2011 47 Male 204 lb 9/13/2011 Consumer United States
Primary
Concomitant
Breath Sounds Abnormal Hospitalization 66 Male 161 lb 6/25/2012 Consumer United States
Primary
Concomitant
Chest X-ray Abnormal Other Serious 61 Female 160 lb 7/2/2012 Consumer United States
Primary
Concomitant
Back Pain Male 7/10/2012 Consumer United States
Primary
Concomitant
Dyspnoea 6/29/2012 86 Female 7/12/2012 Consumer United States
Primary
Concomitant
Implantable Defibrillator Insertion Life Threatening 1/1/2007 65 Female 152 lb 7/17/2012 Consumer United States
Primary
Secondary
Concomitant
Incorrect Route Of Drug Administration 7/10/2012 69 Female 7/19/2012 Consumer United States
Primary
Concomitant
Dyspnoea Hospitalization 6/1/2012 85 Male 7/24/2012 Consumer United States
Primary
Concomitant
Dizziness 7/20/2012 81 Male 7/27/2012 Consumer United States
Primary
Concomitant
Constipation 7/13/2012 64 Female 8/2/2012 Consumer United States
Primary
Concomitant
Death Death Female 8/10/2012 Other Health Professional United States
Primary
Concomitant
Cough 8/6/2012 83 Female 8/17/2012 Consumer United States
Primary
Concomitant
Dyspnoea 7/27/2012 77 Female 8/17/2012 Consumer United States
Primary
Concomitant
Incorrect Route Of Drug Administration 8/14/2012 88 Male 8/20/2012 Consumer United States
Primary
Concomitant
Feeling Abnormal 8/22/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Fatigue 7/13/2012 64 Female 110 lb 8/27/2012 Physician United States
Primary
Concomitant
Ventricular Tachycardia Death 3/17/2009 67 Female 273 lb 9/5/2012 Consumer Us
Primary
Secondary
Concomitant
Scar Pain Other Serious 1/2010 Female 107 lb 11/1/2012 Consumer Country Not Specified
Primary
Concomitant
Sepsis Death 11/12/2009 67 Female 273 lb 9/12/2012 Physician Us
Primary
Secondary
Concomitant
Tremor 69 Male 190 lb 10/10/2012 Us
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 2010 62 Female 277 lb 9/4/2012 Consumer Us
Primary
Secondary
Concomitant
Product Quality Issue 7/27/2012 77 Female 156 lb 9/7/2012 Physician Us
Primary
Concomitant
Tongue Disorder 9/2/2012 59 Male 150 lb 9/14/2012 Consumer Us
Primary
Concomitant
Pallor Hospitalization 9/1/2012 72 Female 10/4/2012 Physician Us
Primary
Concomitant
Volvulus Hospitalization 10/5/2012 81 Female 154 lb 10/31/2012 Consumer Us
Primary
Concomitant
Scab 4/2012 Female 201 lb 11/22/2012 Consumer Us
Primary
Concomitant

Drug Data