Isosorbide Mononitrate combined with Zetia

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Visual Acuity Reduced Other Serious 79 Male 1/12/2006 Consumer United States
Primary
Secondary
Concomitant
Pancreatitis Acute Other Serious 1/7/2006 74 Male 1/18/2006 Other Health Professional United States
Primary
Concomitant
Sudden Death Death 1/6/2006 76 Male 172 lb 3/31/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rectal Haemorrhage Hospitalization 12/9/2005 76 Female 183 lb 4/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 1/7/2004 50 Female 5/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Fibrillation Other Serious 1/6/2006 76 Male 154 lb 5/22/2006 Physician United Kingdom
Primary
Concomitant
Ventricular Fibrillation Other Serious 1/6/2006 77 Male 154 lb 5/23/2006 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 7/10/2005 54 Female 5/24/2006 Pharmacist Australia
Primary
Secondary
Concomitant
Sudden Death Death 1/6/2006 76 Male 172 lb 5/26/2006 Other Health Professional United Kingdom
Primary
Concomitant
Drug Effect Decreased 10/1/2005 63 Male 240 lb 4/3/2006 Consumer United States
Primary
Concomitant
Ventricular Fibrillation Other Serious 1/6/2006 77 Male 154 lb 6/9/2006 Physician United Kingdom
Primary
Concomitant
Tachycardia 2/2/2006 Male 180 lb 8/4/2006 Physician United States
Primary
Concomitant
Swelling Other Serious 5/15/2006 68 Female 126 lb 9/1/2006 Physician United States
Primary
Concomitant
Serum Sickness Other Serious 5/15/2006 68 Female 126 lb 9/13/2006 Physician United States
Primary
Concomitant
Erysipelas Hospitalization 8/27/2006 63 Male 207 lb 9/27/2006 Physician Austria
Primary
Concomitant
Tongue Oedema Other Serious 62 Male 9/28/2006 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2006 62 Male 224 lb 9/29/2006 Physician United States
Primary
Concomitant
Shoulder Operation Other Serious 1/1/2006 Female 141 lb 4/27/2007 Consumer United States
Primary
Secondary
Concomitant
Blood Urea Increased Hospitalization 66 Female 176 lb 4/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 1/27/2007 56 Male 110 lb 4/18/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Shoulder Operation Other Serious 1/1/2006 Female 141 lb 6/29/2007 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2006 Male 162 lb 7/11/2007 Other Health Professional United States
Primary
Concomitant
Interacting
Vision Blurred Other Serious 1/1/2006 Male 162 lb 8/21/2007 Other Health Professional United States
Primary
Concomitant
Interacting
Rhabdomyolysis Hospitalization 6/1/2005 42 Male 8/23/2007 Physician Spain
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 6/1/2005 42 Male 8/30/2007 Physician Spain
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 7/1/2006 66 Female 162 lb 9/12/2007 Physician United States
Primary
Secondary
Concomitant
Lichen Planus Other Serious 3/1/2007 68 Female 9/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hypothyroidism 83 Female 10/1/2007 United States
Primary
Concomitant
Angina Unstable Hospitalization 5/12/2006 65 Male 8/6/2007 Physician United States
Primary
Concomitant
Muscle Spasms Other Serious 1/1/2006 75 Female 192 lb 10/5/2007 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 8/6/2007 50 Male 10/19/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 8/6/2007 50 Male 10/23/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 8/6/2007 50 Male 10/25/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Hypersensitivity Other Serious 62 Male 10/2/2007 United States
Primary
Secondary
Concomitant
Drug Ineffective 57 Male 11/13/2007 Consumer United States
Primary
Concomitant
Tremor 10/30/2007 76 Male 11/21/2007 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Decreased Other Serious 11/1/2007 Female 295 lb 1/29/2008 Physician United States
Primary
Concomitant
Interacting
Rhabdomyolysis Hospitalization 8/6/2007 50 Male 3/7/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Syncope Vasovagal Hospitalization 9/8/2007 75 Female 3/7/2008 United Kingdom
Primary
Concomitant
Parkinson's Disease Other Serious Male 230 lb 4/21/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/14/2004 50 Female 5/9/2008 United Kingdom
Primary
Secondary
Concomitant
Coronary Artery Occlusion Hospitalization 4/1/2008 73 Female 5/15/2008 Consumer United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 6/1/2005 42 Male 5/23/2008 Physician Spain
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 6/1/2005 42 Male 6/3/2008 Physician Spain
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 6/1/2006 53 Male 217 lb 6/18/2008 Other Health Professional United States
Primary
Concomitant
Vitamin D Decreased Other Serious 6/1/2008 Female 7/10/2008 Other Health Professional United States
Primary
Concomitant
Red Blood Cell Sedimentation Rate Increased Other Serious 6/1/2008 75 Male 161 lb 8/8/2008 Other Health Professional United Kingdom
Primary
Concomitant
Vitamin D Decreased Other Serious 6/1/2008 Female 148 lb 8/26/2008 Other Health Professional United States
Primary
Concomitant
Dyspnoea Other Serious 10/1/2007 56 Female 185 lb 8/29/2008 United States
Primary
Concomitant
Sick Sinus Syndrome Hospitalization 10/6/2006 74 Male 9/25/2008 Consumer United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 8/6/2007 50 Male 9/29/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 1/1/2008 74 Female 179 lb 9/29/2008 Consumer United States
Primary
Secondary
Concomitant
Hypertriglyceridaemia Other Serious 10/6/2008 70 Male 10/30/2008 Physician Japan
Primary
Concomitant
Hypertriglyceridaemia Other Serious 10/6/2008 70 Male 11/4/2008 Physician Japan
Primary
Concomitant
Pulmonary Oedema Hospitalization 1/1/2008 74 Female 179 lb 11/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hypertriglyceridaemia 10/6/2008 70 Male 11/11/2008 Physician Japan
Primary
Concomitant
Rhabdomyolysis Other Serious 10/21/2008 72 Female 11/13/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Product Quality Issue Hospitalization 6/20/2008 Female 11/26/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Other Serious 11/1/2008 66 Female 165 lb 12/3/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 4/1/2008 73 Male 232 lb 12/17/2008 Consumer United States
Primary
Concomitant
Pulmonary Oedema Other Serious 1/1/2008 74 Female 179 lb 12/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Product Quality Issue Other Serious 1/1/2007 57 Male 248 lb 12/22/2008 Consumer United States
Primary
Concomitant
Eye Swelling Other Serious 8/6/2007 66 Male 179 lb 12/31/2008 Physician Austria
Primary
Secondary
Concomitant
Product Quality Issue Hospitalization 10/1/2008 47 Female 134 lb 12/30/2008 Consumer United States
Primary
Concomitant
Dyspepsia 2/1/2008 69 Female 265 lb 1/5/2009 Consumer United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 5/1/2007 72 Male 210 lb 1/21/2009 Consumer United States
Primary
Concomitant
Product Quality Issue Death 9/11/2008 67 Male 2/23/2009 Consumer United States
Primary
Concomitant
Headache 2/12/2009 Male 173 lb 3/5/2009 Physician United States
Primary
Concomitant
Product Quality Issue Hospitalization 6/1/2008 63 Male 3/12/2009 Consumer United States
Primary
Concomitant
Cerebral Infarction Hospitalization 7/13/2008 85 Female 4/3/2009 Japan
Primary
Concomitant
Pulmonary Congestion Disability 1/1/2008 79 Female 165 lb 4/16/2009 Physician United States
Primary
Concomitant
Pulmonary Congestion Disability 1/1/2008 79 Female 165 lb 4/21/2009 Physician United States
Primary
Concomitant
Retinal Detachment Other Serious 10/1/2008 Female 202 lb 6/10/2009 Consumer United States
Primary
Concomitant
Renal Impairment Other Serious 6/9/2009 62 Male 8/28/2009 Physician Japan
Primary
Concomitant
Weight Increased Hospitalization 4/1/2009 Female 9/17/2009 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 3/10/1998 54 Male 209 lb 9/23/2009 United States
Primary
Concomitant
Cerebral Infarction Hospitalization 7/13/2008 85 Female 9/16/2009 Japan
Primary
Concomitant
Visual Impairment Other Serious 82 Female 10/18/2009 United States
Primary
Concomitant
Vomiting Other Serious 8/24/2007 66 Female 11/2/2009 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 82 Female 10/26/2009 United States
Primary
Concomitant
Visual Impairment Other Serious 65 Male 11/17/2009 United States
Primary
Concomitant
Vomiting Other Serious 82 Female 11/16/2009 United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious Female 141 lb 12/4/2009 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious Female 141 lb 12/8/2009 Physician United States
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 7/13/2009 85 Female 12/23/2009 Physician Japan
Primary
Concomitant
Peripheral Arterial Occlusive Disease Hospitalization 5/22/2008 68 Female 1/14/2010 Physician Germany
Primary
Concomitant
Ventricular Tachycardia Other Serious 65 Male 1/12/2010 United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 12/24/2006 61 Male 224 lb 1/20/2010 Lawyer United States
Primary
Concomitant
Visual Impairment Other Serious 82 Female 1/21/2010 United States
Primary
Concomitant
Polycythaemia Vera Life Threatening 1/1/2002 Female 135 lb 1/22/2010 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 1/1/1978 61 Male 224 lb 1/26/2010 Lawyer United States
Primary
Concomitant
Chills Hospitalization 11/1/2009 83 Female 138 lb 2/3/2010 Physician United States
Primary
Secondary
Concomitant
Reflux Gastritis Other Serious 9/8/2006 Male 290 lb 2/9/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 8/10/2007 66 Female 2/10/2010 Other Health Professional United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 Male 3/4/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 2/1/2008 44 Male 179 lb 5/3/2010 Lawyer United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 6/3/2010 Other Health Professional United States
Primary
Concomitant
Tongue Discolouration Hospitalization 5/3/2010 74 Female 121 lb 6/30/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 2/1/2008 44 Male 179 lb 7/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tobacco User 1/1/2006 56 Male 260 lb 7/8/2010 Consumer United States
Primary
Concomitant
Sepsis Death 67 Male 7/8/2010 Philippines
Primary
Concomitant
Malaise Other Serious 9/1/2007 67 Male 7/15/2010 Other Health Professional United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Myalgia Other Serious 70 Female 7/22/2010 Pharmacist United States
Primary
Secondary
Vomiting Hospitalization 11/1/2008 8/3/2010 Other Health Professional Algeria
Primary
Secondary
Concomitant
Visual Impairment Other Serious 1/1/2010 64 Male 300 lb 8/16/2010 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 67 Male 8/17/2010 Philippines
Primary
Concomitant
Off Label Use 1/1/2010 80 Female 9/10/2010 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 5/25/2007 66 Female 9/21/2010 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2007 58 Male 137 lb 10/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 10/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 11/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2008 44 Male 179 lb 12/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Cyanosis Death 2/1/2008 67 Male 192 lb 3/4/2011 Other Health Professional United States
Primary
Concomitant
Tremor Disability 3/16/2011 60 Male 179 lb 4/5/2011 Other Health Professional United Kingdom
Primary
Concomitant
Renal Injury Other Serious Male 4/12/2011 Consumer United States
Primary
Concomitant
Confusional State Other Serious 11/1/2007 58 Male 137 lb 4/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Flushing Disability 3/16/2011 60 Male 179 lb 4/18/2011 Other Health Professional United Kingdom
Primary
Concomitant
Arrhythmia Other Serious 12/1/2007 54 Male 163 lb 4/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Dizziness Hospitalization 61 Male 3/31/2011 Consumer United States
Primary
Concomitant
Anhedonia Other Serious 51 Male 195 lb 5/25/2011 Consumer United States
Primary
Concomitant
Injury Other Serious 51 Male 195 lb 6/1/2011 Other Health Professional United States
Primary
Concomitant
Angina Unstable Other Serious Male 6/13/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 7/11/2003 51 Male 195 lb 6/15/2011 Consumer United States
Primary
Concomitant
Renal Injury Other Serious 7/11/2003 51 Male 195 lb 6/30/2011 Other Health Professional United States
Primary
Concomitant
Neck Pain Other Serious 65 Female 178 lb 7/5/2011 Lawyer United States
Primary
Concomitant
Thrombocytopenia Death 12/1/2007 54 Male 163 lb 7/22/2011 Lawyer United States
Primary
Secondary
Concomitant
Cardiac Output Decreased Other Serious 12/1/2007 54 Male 163 lb 7/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Abdominal Pain Upper 83 Female 7/25/2011 Consumer United States
Primary
Concomitant
Intervertebral Disc Degeneration Other Serious Male 8/8/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Asthenia 1/1/2010 75 Male 261 lb 8/19/2011 Consumer United States
Primary
Concomitant
Bladder Cancer Life Threatening 6/16/2010 55 Male 8/15/2011 Other Health Professional Japan
Primary
Concomitant
Death Hospitalization 69 Male 8/19/2011 Lawyer United States
Primary
Concomitant
Nausea Other Serious Male 8/30/2011 United States
Primary
Concomitant
Interacting
Malaise Other Serious Male 9/2/2011 Consumer United States
Primary
Concomitant
Interacting
Cardiac Disorder Other Serious Male 9/14/2011 Physician United States
Primary
Concomitant
Interacting
Hyperparathyroidism Hospitalization Male 10/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Potassium Increased Hospitalization 9/14/2010 75 Female 10/10/2011 Physician Japan
Primary
Concomitant
Anaemia Other Serious 11/1/2007 58 Male 137 lb 10/17/2011 Lawyer United States
Primary
Secondary
Concomitant
Electrocardiogram St-t Change Other Serious Male 10/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Constipation Hospitalization 5/5/2009 56 Male 10/24/2011 Physician United States
Primary
Secondary
Concomitant
Cholelithiasis Death 12/1/2007 54 Male 163 lb 11/16/2011 Lawyer United States
Primary
Secondary
Concomitant
Cardiac Disorder 2/5/2010 81 Male 239 lb 12/19/2011 Other Health Professional United States
Primary
Concomitant
Pruritus Generalised Other Serious Female 12/27/2011 Consumer United States
Primary
Secondary
Concomitant
Pruritus Generalised Other Serious Female 12/27/2011 Physician United States
Primary
Secondary
Concomitant
Clumsiness Other Serious 4/9/2011 66 Male 1/3/2012 Consumer United States
Primary
Secondary
Concomitant
Drug Dose Omission Other Serious 72 Female 160 lb 1/5/2012 United States
Primary
Secondary
Concomitant
Drug Dose Omission 10/1/2010 59 Male 254 lb 1/27/2012 Consumer United States
Primary
Concomitant
Iron Deficiency Anaemia Hospitalization 9/14/2010 75 Female 1/31/2012 Physician Japan
Primary
Concomitant
Lymphocyte Count Decreased Other Serious 5/5/2009 56 Male 2/15/2012 Consumer United States
Primary
Secondary
Concomitant

Drug Data