Isosorbide Mononitrate combined with Toprol-XL

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Visual Acuity Reduced Other Serious 79 Male 1/12/2006 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 1/1/2000 62 Female 187 lb 1/17/2006 Lawyer United States
Primary
Concomitant
Middle Insomnia 6/1/2005 58 Male 250 lb 1/5/2006 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2000 57 Female 150 lb 3/3/2006 Lawyer United States
Primary
Concomitant
Sick Sinus Syndrome Other Serious 1/1/2001 64 Male 209 lb 3/16/2006 Physician United States
Primary
Concomitant
Sick Sinus Syndrome Other Serious 1/1/2001 64 Male 209 lb 3/21/2006 Physician United States
Primary
Concomitant
Oedema Peripheral Other Serious 12/8/2003 66 Female 181 lb 3/23/2006 Lawyer United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 1/1/2002 49 Male 209 lb 3/27/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Hospitalization 6/1/2000 66 Female 157 lb 3/31/2006 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 1/1/2005 Male 200 lb 4/10/2006 Consumer United States
Primary
Concomitant
Oedema Peripheral Other Serious 12/8/2003 66 Female 181 lb 4/17/2006 Lawyer United States
Primary
Concomitant
Sick Sinus Syndrome Other Serious 1/1/2001 64 Male 209 lb 4/17/2006 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 2/26/2006 64 Female 195 lb 4/13/2006 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Death 4/24/2004 67 Male 165 lb 4/24/2006 Physician United States
Primary
Concomitant
Tachycardia Hospitalization 69 Female 198 lb 4/20/2006 Other Health Professional United States
Primary
Concomitant
Alopecia 1/1/2006 85 Female 2/17/2006 Consumer United States
Primary
Concomitant
Sick Sinus Syndrome Other Serious 1/1/2001 64 Male 209 lb 5/11/2006 Physician United States
Primary
Concomitant
Respiratory Arrest Hospitalization 5/12/2006 Female 175 lb 6/8/2006 Consumer
Primary
Concomitant
Myalgia Other Serious Female 135 lb 6/7/2006 United States
Primary
Secondary
Concomitant
Macular Oedema 10/1/2005 74 Male 5/19/2006 Physician United States
Primary
Concomitant
Unevaluable Event 1/1/2006 85 Female 5/24/2006 Consumer United States
Primary
Concomitant
Tongue Oedema Other Serious 3/15/2006 87 Female 6/21/2006 United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 7/24/2006 72 Male 185 lb 7/25/2006 Other Health Professional United States
Primary
Concomitant
Syncope Hospitalization 5/1/2006 75 Male 7/25/2006 United States
Primary
Secondary
Concomitant
Periorbital Oedema 5/1/2006 72 Male 143 lb 8/29/2006 Consumer United States
Primary
Concomitant
Tongue Oedema Other Serious 62 Male 9/28/2006 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2006 62 Male 224 lb 9/29/2006 Physician United States
Primary
Concomitant
Sleep Disorder Hospitalization 3/1/2006 Male 11/20/2006 Consumer United States
Primary
Secondary
Concomitant
Swelling 12/1/2005 77 Male 12/28/2006 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2005 51 Female 198 lb 9/12/2006 United States
Primary
Concomitant
Pain In Extremity 1/1/2006 66 Female 162 lb 10/24/2006 Pharmacist United States
Primary
Concomitant
Pharmaceutical Product Complaint 2/1/2007 56 Female 320 lb 2/23/2007 Other Health Professional United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/8/2007 56 Female 320 lb 3/2/2007 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/8/2007 56 Female 320 lb 3/12/2007 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/8/2007 56 Female 320 lb 3/28/2007 Consumer United States
Primary
Concomitant
Visual Acuity Reduced 3/1/2006 80 Male 138 lb 2/22/2007 United States
Primary
Concomitant
Suicidal Ideation 10/27/2006 41 Male 2/28/2007 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral Hospitalization 4/26/2006 78 Male 3/9/2007 Consumer United States
Primary
Concomitant
Lung Neoplasm Hospitalization 3/27/2007 Male 205 lb 6/18/2007 Physician United States
Primary
Secondary
Concomitant
Urine Flow Decreased Other Serious 5/1/2006 59 Female 4/26/2007 United States
Primary
Concomitant
Myocardial Infarction Other Serious 8/12/2000 Female 146 lb 7/24/2007 Lawyer United States
Primary
Secondary
Concomitant
Myocardial Infarction Death 6/25/2007 Male 118 lb 8/1/2007 Other Health Professional United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 6/10/2007 52 Male 8/31/2007 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 10/8/2006 78 Female 9/7/2007 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 57 Female 147 lb 9/12/2007 Consumer United States
Primary
Concomitant
Pain In Jaw Other Serious 7/1/2006 66 Female 162 lb 9/12/2007 Physician United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 7/28/2007 56 Female 9/28/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Headache 8/12/2007 79 Male 10/24/2007 Consumer United States
Primary
Concomitant
Hypersensitivity Other Serious 62 Male 10/2/2007 United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/30/2006 60 Female 11/10/2007 Pharmacist United States
Primary
Concomitant
Lung Infiltration Hospitalization 3/27/2007 Male 205 lb 11/20/2007 Physician United States
Primary
Secondary
Concomitant
Alopecia 79 Male 1/14/2008 Consumer United States
Primary
Concomitant
Myocardial Infarction Death 6/25/2007 Male 118 lb 1/16/2008 Other Health Professional United States
Primary
Concomitant
Mental Status Changes Hospitalization 7/28/2007 56 Female 1/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Hospitalization 56 Female 2/7/2008 Other Health Professional United States
Primary
Concomitant
Interacting
Mental Status Changes Hospitalization 2/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 56 Female 2/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased 3/1/2007 69 Male 292 lb 1/10/2008 Consumer United States
Primary
Concomitant
Renal Mass Hospitalization 2/15/2008 Male 228 lb 3/18/2008 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 80 Female 99 lb 3/28/2008 Consumer United States
Primary
Concomitant
Mental Status Changes Hospitalization 56 Female 4/7/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Prostatic Specific Antigen Increased Other Serious 5/11/2004 Male 198 lb 4/16/2008 Consumer United States
Primary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Hospitalization Female 150 lb 4/14/2008 United States
Primary
Concomitant
Urinary Retention Other Serious 2/1/2008 Female 137 lb 4/30/2008 Consumer United States
Primary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Hospitalization Female 150 lb 5/22/2008 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious Female 3/27/2008 Consumer United States
Primary
Concomitant
No Adverse Event 2/15/2008 Male 228 lb 8/11/2008 United States
Primary
Concomitant
Dyspnoea Other Serious 10/1/2007 56 Female 185 lb 8/29/2008 United States
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 9/17/2008 Lawyer United States
Primary
Concomitant
Lethargy Other Serious 4/18/2005 Male 10/17/2008 Physician United States
Primary
Concomitant
Lethargy Other Serious 4/18/2005 Male 10/24/2008 Consumer United States
Primary
Concomitant
Dysgeusia 9/1/2008 68 Female 10/24/2008 Consumer
Primary
Concomitant
Dysgeusia 9/1/2008 68 Female 11/17/2008 Consumer
Primary
Concomitant
Product Quality Issue Other Serious 1/1/2008 50 Female 155 lb 12/9/2008 Consumer United States
Primary
Concomitant
Syncope Hospitalization 4/1/2008 87 Female 100 lb 12/15/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 4/1/2008 73 Male 232 lb 12/17/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 10/1/2008 59 Male 285 lb 12/17/2008 Consumer United States
Primary
Concomitant
Renal Function Test Abnormal Other Serious 10/5/2008 55 Male 12/19/2008 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 8/1/2008 90 Female 140 lb 12/19/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 1/1/2007 64 Male 12/19/2008 Consumer United States
Primary
Concomitant
Tracheal Stenosis Required Intervention 10/4/2008 83 Male 215 lb 12/22/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 7/24/2008 73 Female 148 lb 12/23/2008 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 11/12/2008 81 Female 175 lb 12/30/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 5/8/2008 83 Male 220 lb 12/30/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Other Serious 1/1/2007 86 Female 12/30/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 10/29/2006 76 Female 12/30/2008 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 5/1/2007 72 Male 210 lb 1/21/2009 Consumer United States
Primary
Concomitant
Mental Status Changes 56 Female 8/20/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 2/18/2009 67 Female 187 lb 3/9/2009 Other Health Professional United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 2/18/2009 67 Female 188 lb 3/4/2009 Other Health Professional United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 2/18/2009 67 Female 188 lb 3/4/2009 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 2/18/2009 67 Female 185 lb 3/10/2009 Other Health Professional United States
Primary
Concomitant
Osteoarthritis Other Serious 11/1/2008 Male 4/8/2009 Physician United States
Primary
Concomitant
Osteoarthritis Other Serious 11/1/2008 Male 196 lb 4/10/2009 Physician United States
Primary
Concomitant
Osteoarthritis Other Serious 11/1/2008 Male 196 lb 4/22/2009 Physician United States
Primary
Concomitant
Osteoarthritis Other Serious 11/1/2008 Male 181 lb 4/28/2009 Physician United States
Primary
Concomitant
Osteoarthritis Other Serious 11/1/2008 Male 181 lb 5/21/2009 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/22/2000 45 Male 266 lb 7/10/2009 United States
Primary
Concomitant
Presyncope Hospitalization 3/21/2009 Male 8/31/2009 United States
Primary
Secondary
Pancreatitis Acute Other Serious 6/27/2009 69 Male 9/8/2009 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 3/10/1998 54 Male 209 lb 9/23/2009 United States
Primary
Concomitant
Pancreatitis Acute Other Serious 6/27/2009 69 Male 9/28/2009 Physician United States
Primary
Concomitant
Vomiting Other Serious 8/24/2007 66 Female 11/2/2009 Lawyer United States
Primary
Concomitant
Skin Discolouration Hospitalization 10/1/2009 Male 200 lb 11/19/2009 Consumer United States
Primary
Concomitant
Yellow Skin Hospitalization 10/1/2009 Male 200 lb 11/20/2009 Consumer United States
Primary
Concomitant
Visual Impairment Other Serious 65 Male 11/17/2009 United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 64 Male 11/18/2009 United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 10/30/2009 80 Female 147 lb 12/8/2009 Other Health Professional United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 64 Male 12/1/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 67 Female 138 lb 1/14/2010 United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 64 Male 1/8/2010 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 65 Male 1/12/2010 United States
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 1/25/2010 Consumer United States
Primary
Concomitant
Wheezing Hospitalization 11/27/2006 76 Female 145 lb 1/20/2010 Lawyer United States
Primary
Concomitant
Chills Hospitalization 11/1/2009 83 Female 138 lb 2/3/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 67 Female 138 lb 2/1/2010 United States
Primary
Secondary
Concomitant
Reflux Gastritis Other Serious 9/8/2006 Male 290 lb 2/9/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 8/10/2007 66 Female 2/10/2010 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 11/1/2007 73 Male 152 lb 2/10/2010 Lawyer United States
Primary
Concomitant
Pancreatitis Acute Other Serious 6/27/2009 69 Male 2/11/2010 Physician United States
Primary
Concomitant
Pancreatitis Acute Other Serious 6/27/2009 69 Male 3/2/2010 Physician United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 Male 3/4/2010 Lawyer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2007 58 Male 137 lb 3/4/2010 Lawyer United States
Primary
Concomitant
Wheezing Hospitalization 11/27/2006 76 Female 145 lb 3/3/2010 Lawyer United States
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 4/16/2010 Other Health Professional United States
Primary
Concomitant
Renal Cyst Hospitalization 7/31/2008 70 Male 164 lb 5/5/2010 Physician United States
Primary
Secondary
Concomitant
Pancreatic Neoplasm Hospitalization 7/31/2008 70 Male 164 lb 5/13/2010 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 3/1/2008 68 Female 5/24/2010 Lawyer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2007 58 Male 137 lb 5/28/2010 Physician United States
Primary
Secondary
Concomitant
Pancreatic Neoplasm Hospitalization 7/31/2008 70 Male 164 lb 6/3/2010 Physician United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 6/3/2010 Other Health Professional United States
Primary
Concomitant
Pancreatic Neoplasm Hospitalization 7/31/2008 70 Male 164 lb 6/24/2010 Physician United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 7/26/2009 70 Female 239 lb 6/16/2010 Pharmacist United States
Primary
Concomitant
Flatulence 2/1/2007 66 Male 148 lb 7/9/2010 Consumer United States
Primary
Concomitant
International Normalised Ratio Abnormal 3/15/2007 75 Male 210 lb 7/12/2010 Consumer United States
Primary
Secondary
Concomitant
Nausea 2/21/2007 65 Female 168 lb 7/12/2010 Other Health Professional United States
Primary
Concomitant
Visual Impairment Other Serious 4/25/2007 57 Female 145 lb 7/13/2010 Consumer United States
Primary
Concomitant
Insomnia 7/14/2007 75 Male 150 lb 7/14/2010 Consumer United States
Primary
Concomitant
Mental Status Changes Hospitalization 7/28/2007 56 Female 7/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Other Serious 11/7/2007 56 Male 328 lb 7/17/2010 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Supraventricular Tachycardia Other Serious 2/1/2008 68 Female 115 lb 7/22/2010 Lawyer United States
Primary
Concomitant
Pancreatic Neoplasm Hospitalization 7/31/2008 70 Male 164 lb 8/31/2010 Physician United States
Primary
Secondary
Concomitant
Pancreatic Neoplasm Hospitalization 7/31/2008 70 Male 164 lb 9/2/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/1/2007 52 Male 176 lb 9/2/2010 Other Health Professional United States
Primary
Concomitant
Off Label Use 1/1/2010 80 Female 9/10/2010 Pharmacist United States
Primary
Concomitant
Nausea 4/1/2010 63 Female 174 lb 9/16/2010 Consumer United States
Primary
Secondary
Concomitant
Proteus Infection Hospitalization 7/31/2008 70 Male 164 lb 9/21/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/6/2008 51 Male 163 lb 9/21/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 5/25/2007 66 Female 9/21/2010 Other Health Professional United States
Primary
Concomitant

Drug Data