Isosorbide Mononitrate combined with Ranitidine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hepatitis Hospitalization 2/9/2005 69 Male 4/4/2005 Other Health Professional United States
Primary
Secondary
Concomitant
Parkinsonism Hospitalization 9/5/2005 52 Male 2/6/2006 Germany
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/19/2005 77 Female 115 lb 2/16/2006 Poland
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/19/2005 77 Female 115 lb 2/28/2006 Poland
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Hospitalization 1/1/1999 73 Female 165 lb 3/6/2006 Lawyer United States
Primary
Concomitant
Tinnitus Hospitalization 8/1/2001 78 Female 3/31/2006 Lawyer Poland
Primary
Concomitant
Tinnitus Hospitalization 8/1/2001 78 Female 4/7/2006 Physician Poland
Primary
Concomitant
Hypoglycaemia Hospitalization 3/17/2006 46 Female 4/13/2006 Other Health Professional Netherlands
Primary
Concomitant
Hypoglycaemia Hospitalization 3/17/2006 46 Female 4/17/2006 Other Health Professional Netherlands
Primary
Concomitant
Rhinitis Allergic Hospitalization 4/1/2003 49 Male 218 lb 5/5/2006 Physician United States
Primary
Concomitant
Photosensitivity Reaction Other Serious 9/21/2005 80 Male 5/8/2006 Pharmacist Australia
Primary
Concomitant
Urinary Tract Infection Hospitalization 12/22/2005 87 Male 5/1/2006 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Enterococcal Life Threatening 12/22/2005 87 Male 5/10/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Enterococcal Life Threatening 12/22/2005 87 Male 5/19/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 12/22/2005 87 Male 5/26/2006 United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Enterococcal Life Threatening 12/22/2005 87 Male 6/7/2006 United Kingdom
Primary
Secondary
Concomitant
Hypovolaemia Hospitalization 5/17/2006 Female 6/30/2006 United Kingdom
Primary
Secondary
Concomitant
Bronchitis Hospitalization 10/22/2005 64 Male 7/14/2006 United States
Primary
Secondary
Concomitant
Hypovolaemia Hospitalization 5/17/2006 85 Female 7/31/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Hypovolaemia Hospitalization 5/17/2006 85 Female 8/11/2006 United Kingdom
Primary
Secondary
Concomitant
Hypovolaemia Other Serious 5/17/2006 Female 8/18/2006 Other Health Professional Denmark
Primary
Concomitant
Muscular Weakness Hospitalization 12/1/2005 73 Male 8/28/2006 Physician France
Primary
Concomitant
Vomiting Other Serious 10/21/2006 85 Female 12/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Hypertrophy Death 61 Male 11/30/2006 Austria
Primary
Secondary
Ventricular Hypertrophy Hospitalization Male 12/7/2006 Physician Austria
Primary
Concomitant
Vomiting Other Serious 10/21/2006 85 Female 12/11/2006 Other Health Professional United Kingdom
Primary
Concomitant
Presyncope Hospitalization 9/8/2006 Male 209 lb 11/4/2006 Pharmacist United States
Primary
Concomitant
Hip Fracture Hospitalization 4/8/2006 Female 146 lb 2/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pain In Extremity Other Serious 85 Female 5/15/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 85 Female 5/22/2007 United Kingdom
Primary
Secondary
Concomitant
Somnolence Life Threatening 4/18/2007 56 Male 8/3/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Life Threatening 4/18/2007 56 Male 8/1/2007 United Kingdom
Primary
Secondary
Concomitant
Somnolence Life Threatening 4/18/2007 56 Male 8/1/2007 United Kingdom
Primary
Secondary
Concomitant
Vision Blurred Required Intervention 8/15/2007 68 Male 9/7/2007 United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 75 Female 121 lb 12/18/2007 Norway
Primary
Secondary
Concomitant
Mass 1/1/2008 Female 114 lb 3/15/2008 Consumer United States
Primary
Concomitant
Hypoglycaemia Hospitalization 6/8/2007 Female 5/28/2008 Consumer United States
Primary
Secondary
Concomitant
Blood Glucose Increased Other Serious 5/15/2008 Female 140 lb 5/30/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 10/21/2006 85 Female 8/9/2008 United Kingdom
Primary
Concomitant
Hypovolaemia Other Serious 5/17/2006 Female 10/22/2008 Denmark
Primary
Concomitant
Syncope Other Serious 10/4/2008 56 Female 175 lb 11/29/2008 United States
Primary
Concomitant
Flatulence 4/1/2008 78 Female 155 lb 12/17/2008 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 1/1/2003 52 Male 282 lb 1/5/2009 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 71 Male 196 lb 4/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Death 3/27/2009 Male 4/29/2009 Physician United States
Primary
Concomitant
Hypotension Hospitalization 5/19/2009 Male 6/2/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Hyperhidrosis Hospitalization 82 Female 9/30/2009 United Kingdom
Primary
Concomitant
Cardiogenic Shock Death 8/19/2009 57 Male 10/9/2009 Other Health Professional United Kingdom
Primary
Concomitant
Oxygen Saturation Decreased Other Serious 9/17/2009 74 Male 11/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Wheezing Hospitalization 11/27/2006 76 Female 145 lb 1/20/2010 Lawyer United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 Male 3/4/2010 Lawyer United States
Primary
Concomitant
Wheezing Hospitalization 11/27/2006 76 Female 145 lb 3/3/2010 Lawyer United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 6/3/2010 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Hospitalization 4/29/2010 59 Male 6/18/2010 Other Health Professional United Kingdom
Primary
Concomitant
Malaise Other Serious 4/29/2010 59 Male 6/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Sleep Disorder 12/1/2007 54 Male 190 lb 7/21/2010 Consumer United States
Primary
Concomitant
Anxiety 9/28/2010 65 Male 160 lb 10/7/2010 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 10/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 11/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Vertigo Other Serious 9/28/2010 65 Male 160 lb 11/3/2010 Consumer United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 2/21/2008 69 Female 150 lb 12/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 11/11/2010 Male 12/9/2010 Other Health Professional United Kingdom
Primary
Concomitant
Off Label Use Other Serious 11/21/2010 Male 152 lb 12/27/2010 Consumer China
Primary
Concomitant
Sinus Tachycardia Other Serious 2/21/2008 69 Female 150 lb 1/31/2011 Pharmacist United States
Primary
Secondary
Concomitant
Myopathy Hospitalization 2/3/2011 69 Male 2/22/2011 Other Health Professional United Kingdom
Primary
Concomitant
Diarrhoea Hospitalization 12/30/2010 67 Male 164 lb 2/28/2011 Other Health Professional United Kingdom
Primary
Concomitant
Bronchospasm Other Serious 71 Male 2/28/2011 Other Health Professional United Kingdom
Primary
Concomitant
Anaphylactic Reaction Other Serious 71 Male 3/1/2011 Other Health Professional United Kingdom
Primary
Concomitant
Fibrinolysis Life Threatening 71 Male 3/4/2011 Consumer United Kingdom
Primary
Concomitant
Ventricular Fibrillation Life Threatening 71 Male 3/21/2011 Other Health Professional United Kingdom
Primary
Concomitant
Rapid Correction Of Hyponatraemia Life Threatening 12/9/2010 76 Male 3/9/2011 Other Health Professional United Kingdom
Primary
Concomitant
Pain Death 2/19/2007 75 Male 200 lb 4/16/2011 Other Health Professional United States
Primary
Concomitant
Arrhythmia Other Serious 12/1/2007 54 Male 163 lb 4/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Pressure Increased Other Serious 12/1/2009 50 Male 175 lb 4/21/2011 Consumer United States
Primary
Concomitant
Dystonia Other Serious 7/1/2009 58 Female 175 lb 5/23/2011 Lawyer United States
Primary
Concomitant
Death Death 82 Male 6/15/2011 Physician United Kingdom
Primary
Concomitant
Renal Impairment Hospitalization 88 Male 6/15/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Chorea Disability 1/1/2003 61 Female 6/22/2011 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 4/17/2011 85 Male 7/8/2011 Consumer Switzerland
Primary
Concomitant
Diabetic Vascular Disorder Other Serious 6/2/2004 68 Female 287 lb 7/12/2011 Physician United States
Primary
Concomitant
Renal Failure Chronic Other Serious 11/1/2009 64 Male 230 lb 7/13/2011 Physician United States
Primary
Concomitant
Thrombocytopenia Death 12/1/2007 54 Male 163 lb 7/22/2011 Lawyer United States
Primary
Secondary
Concomitant
Cardiac Output Decreased Other Serious 12/1/2007 54 Male 163 lb 7/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Death 9/25/2010 76 Male 123 lb 7/29/2011 Physician Serbia
Primary
Concomitant
Abnormal Behaviour Hospitalization 67 Female 7/28/2011 Physician United States
Primary
Concomitant
Cerebrovascular Accident Death 9/25/2010 76 Male 123 lb 8/2/2011 Physician Serbia
Primary
Concomitant
Myocardial Infarction Life Threatening 4/17/2011 85 Male 8/25/2011 Other Health Professional Switzerland
Primary
Concomitant
Sepsis Death Female 9/21/2011 Other Health Professional United Kingdom
Primary
Concomitant
Cholelithiasis Death 12/1/2007 54 Male 163 lb 11/16/2011 Lawyer United States
Primary
Secondary
Concomitant
Epistaxis 10/30/2011 84 Male 11/17/2011 Consumer United States
Primary
Concomitant
Cerebral Haematoma Other Serious 6/5/2011 78 Male 11/29/2011 Physician Spain
Primary
Concomitant
Interacting
Atrial Fibrillation Hospitalization 6/5/2011 78 Male 12/7/2011 Physician Spain
Primary
Concomitant
Interacting
Renal Failure Acute Hospitalization 11/9/2011 75 Female 134 lb 12/8/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 11/9/2011 75 Female 134 lb 12/12/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 11/9/2011 75 Female 134 lb 12/15/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 11/9/2011 75 Female 134 lb 12/15/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 11/9/2011 75 Female 134 lb 12/15/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Atrial Flutter Other Serious 1/9/2008 61 Female 193 lb 12/8/2011 Lawyer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 11/9/2011 75 Female 134 lb 12/16/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 6/8/2011 84 Male 143 lb 12/27/2011 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 11/9/2011 75 Female 134 lb 12/28/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 6/8/2011 84 Male 143 lb 12/29/2011 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Contusion 10/30/2011 84 Male 1/12/2012 Consumer United States
Primary
Concomitant
Oesophageal Ulcer Hospitalization 73 Female 119 lb 1/23/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Ineffective 12/1/2010 68 Male 1/27/2012 Consumer United States
Primary
Concomitant
Anaemia Other Serious 1/1/2009 72 Male 2/7/2012 Consumer Brazil
Primary
Concomitant
Myalgia 56 Female 175 lb 12/20/2011 Consumer United States
Primary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 2/8/2012 61 Male 278 lb 3/1/2012 Physician Japan
Primary
Secondary
Concomitant
Rib Fracture Death 1/1/2008 61 Female 3/15/2012 Lawyer United States
Primary
Concomitant
Fracture Death 1/1/2008 61 Female 5/10/2012 United States
Primary
Concomitant
Osteoporosis Hospitalization 1/1/2008 61 Female 5/21/2012 United States
Primary
Concomitant
Upper Limb Fracture Death 1/4/2006 61 Female 6/8/2012 Lawyer United States
Primary
Concomitant
Back Pain Other Serious 6/8/2012 67 Female 138 lb 6/14/2012 Consumer United States
Primary
Concomitant
Haemorrhoids 3/11/2012 54 Male 220 lb 6/19/2012 Consumer
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 2/2/2004 61 Female 6/25/2012 Lawyer United States
Primary
Concomitant
Dizziness Hospitalization 3/25/2010 47 Male 203 lb 6/25/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Type 1 Diabetes Mellitus Hospitalization 2/2/2004 61 Female 6/28/2012 United States
Primary
Concomitant
Dizziness Hospitalization 3/25/2010 47 Male 6/21/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Angina Pectoris 1/1/2011 7/31/2012 Physician United States
Primary
Concomitant
Paraesthesia 1/1/2010 56 Male 285 lb 8/3/2012 Consumer United States
Primary
Concomitant
Hallucination Death 65 Female 8/24/2012 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Granuloma Other Serious 1/2012 Male 157 lb 9/12/2012 Physician Us
Primary
Concomitant
Kidney Transplant Rejection Other Serious 12/30/2011 53 Female 141 lb 12/14/2012 Pharmacist Us
Primary
Concomitant
Hypoglycaemia Hospitalization 5/23/2012 60 Male 12/27/2012 Consumer Us
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 5/8/2012 85 Male 155 lb 9/13/2012 Other Health Professional Gb
Primary
Concomitant
Stress Other Serious 66 Male 199 lb 8/2/2013 Us
Primary
Secondary
Concomitant
Oral Candidiasis Other Serious 9/2012 Male 295 lb 11/16/2012 Consumer Country Not Specified
Primary
Concomitant
Chest Pain Hospitalization 85 Male 220 lb 11/19/2012 Other Health Professional Us
Primary
Concomitant
Diaphragmatic Hernia Hospitalization 85 Male 215 lb 11/19/2012 Other Health Professional Us
Primary
Concomitant
Prostatic Disorder Hospitalization 85 Male 219 lb 11/19/2012 Other Health Professional Us
Primary
Concomitant
Nasal Disorder Hospitalization 85 Male 214 lb 11/19/2012 Other Health Professional Us
Primary
Concomitant
Dyspnoea Hospitalization 86 Male 218 lb 11/19/2012 Other Health Professional Us
Primary
Concomitant
Prostatic Disorder Hospitalization 86 Male 225 lb 11/22/2012 Other Health Professional Us
Primary
Concomitant
Weight Fluctuation Other Serious 11/2012 Male 217 lb 12/19/2012 Consumer Us
Primary
Concomitant
Restless Legs Syndrome Hospitalization Female 12/27/2012 Pharmacist Gb
Primary
Concomitant
Restless Legs Syndrome Hospitalization 74 Female 5/29/2013 Pharmacist Gb
Primary
Concomitant
Subdural Haematoma Hospitalization 12/8/2012 62 Female 1/3/2013 Consumer Us
Primary
Concomitant
Restless Legs Syndrome Hospitalization 74 Female 12/21/2012 Other Health Professional Dk
Primary
Concomitant
Restless Legs Syndrome Hospitalization 74 Female 1/9/2013 Pharmacist Gb
Primary
Concomitant
Haemorrhage Other Serious 2/9/2013 79 Female 3/29/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Protein C Decreased Other Serious 2/9/2013 78 Female 4/3/2013 Other Health Professional Us
Primary
Concomitant
Interacting
Uveitis Disability 4/2/2013 63 Male 159 lb 4/30/2013 Physician Gb
Primary
Concomitant
Neutropenic Sepsis Hospitalization 4/22/2013 77 Male 162 lb 6/10/2013 Physician Gb
Primary
Secondary
Concomitant
Infection Hospitalization 10/5/2012 78 Male 162 lb 5/1/2013 Physician Gb
Primary
Secondary
Concomitant
Weight Increased Other Serious 11/2009 66 Female 206 lb 7/25/2013 Consumer Us
Primary
Secondary
Concomitant
Nasal Congestion Other Serious 4/30/2013 64 Male 151 lb 5/22/2013 Physician Gb
Primary
Concomitant
Nasal Congestion Other Serious 4/30/2013 64 Male 151 lb 5/17/2013 Other Health Professional Gb
Primary
Concomitant
Nasal Congestion Other Serious 4/30/2013 64 Male 151 lb 5/21/2013 Physician Gb
Primary
Concomitant
Nasal Congestion Other Serious 4/30/2013 64 Male 150 lb 5/22/2013 Other Health Professional Gb
Primary
Concomitant

Drug Data