Isosorbide Mononitrate combined with Pravastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pain In Extremity Other Serious 10/14/2005 75 Male 210 lb 1/17/2006 Other Health Professional United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 2/1/2006 75 Female 3/6/2006 Pharmacist Japan
Primary
Concomitant
Odynophagia Hospitalization 1/15/2006 71 Male 3/10/2006 Physician Japan
Primary
Secondary
Respiratory Failure Life Threatening 12/13/2005 74 Male 84 lb 3/10/2006 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 2/1/2006 70 Female 3/15/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 2/1/2006 70 Female 3/15/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Angioneurotic Oedema Hospitalization 1/15/2006 71 Male 3/17/2006 Physician Japan
Primary
Secondary
White Blood Cell Count Increased Hospitalization 1/15/2006 71 Male 4/3/2006 Physician Japan
Primary
Secondary
Vertigo Hospitalization 73 Male 6/7/2006 Other Health Professional France
Primary
Secondary
Pancytopenia Hospitalization 6/30/2006 Male 8/3/2006 Other Health Professional Japan
Primary
Concomitant
Fall Hospitalization Male 8/21/2006 Pharmacist United Kingdom
Primary
Concomitant
Nervous System Disorder Other Serious 6/14/2006 Female 108 lb 9/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vascular Dementia Hospitalization 7/6/2006 74 Male 170 lb 9/15/2006 Physician Netherlands
Primary
Concomitant
Nervous System Disorder Other Serious 6/14/2006 Female 108 lb 10/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vascular Dementia Hospitalization 7/6/2006 74 Male 170 lb 10/17/2006 Physician Netherlands
Primary
Concomitant
Hallucination Hospitalization 9/30/2006 65 Male 128 lb 12/13/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/3/2004 63 Female 1/22/2007 United Kingdom
Primary
Concomitant
Vascular Dementia Hospitalization 7/6/2006 Male 170 lb 2/15/2007 Netherlands
Primary
Concomitant
Therapeutic Response Unexpected 67 Female 3/7/2007 Consumer United States
Primary
Concomitant
Liver Disorder Other Serious 1/5/2007 55 Male 4/12/2007 Japan
Primary
Concomitant
Visual Acuity Reduced 3/1/2006 80 Male 138 lb 2/22/2007 United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/3/2004 Female 154 lb 5/29/2007 Physician United Kingdom
Primary
Concomitant
Cerebellar Ataxia Other Serious 6/14/2006 Female 108 lb 7/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Skin Hypertrophy Other Serious 70 Male 6/29/2007 Other Health Professional Greece
Primary
Concomitant
Mental Status Changes Hospitalization 7/28/2007 56 Female 9/28/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Cholelithiasis Hospitalization 5/22/2007 Female 110 lb 11/19/2007 United Kingdom
Primary
Concomitant
Ventricular Tachycardia Death 3/5/2007 88 Female 156 lb 12/7/2007 Pharmacist United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 12/6/2007 66 Female 151 lb 12/18/2007 Physician Hungary
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 7/28/2007 56 Female 1/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Gynaecomastia Other Serious 2/4/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Cerebral Infarction Disability 7/28/2007 74 Female 137 lb 1/24/2008 Physician Japan
Primary
Concomitant
Pharmaceutical Product Complaint Hospitalization 56 Female 2/7/2008 Other Health Professional United States
Primary
Concomitant
Interacting
Mental Status Changes Hospitalization 2/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 56 Female 2/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Impairment Disability 7/28/2007 74 Female 137 lb 2/27/2008 Physician Japan
Primary
Concomitant
Mental Status Changes Hospitalization 56 Female 4/7/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Hospitalization Female 150 lb 4/14/2008 United States
Primary
Concomitant
Coronary Artery Occlusion Hospitalization 4/1/2008 73 Female 5/15/2008 Consumer United States
Primary
Secondary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Hospitalization Female 150 lb 5/22/2008 United States
Primary
Concomitant
Acute Coronary Syndrome Hospitalization 4/22/2008 Male 6/27/2008 Netherlands
Primary
Concomitant
Haematuria Other Serious 6/3/2003 Male 7/7/2008 Other Health Professional Sweden
Primary
Concomitant
Interacting
Withdrawal Syndrome Other Serious 9/22/2008 82 Female 11/24/2008 Physician Germany
Primary
Secondary
Concomitant
Restlessness Hospitalization 11/5/2008 74 Male 215 lb 12/8/2008 Consumer United States
Primary
Concomitant
Troponin Increased Other Serious 10/1/2008 Female 154 lb 12/29/2008 Consumer Ireland
Primary
Concomitant
Product Quality Issue Hospitalization 10/1/2008 47 Female 134 lb 12/30/2008 Consumer United States
Primary
Concomitant
Malignant Neoplasm Progression Hospitalization 6/24/2008 76 Male 119 lb 1/12/2009 Physician Japan
Primary
Concomitant
Product Quality Issue Hospitalization 11/26/2008 76 Female 215 lb 1/22/2009 Consumer United States
Primary
Concomitant
Mental Status Changes 56 Female 8/20/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Product Quality Issue Hospitalization 5/1/2008 74 Female 2/20/2009 Consumer United States
Primary
Concomitant
Muscular Weakness Hospitalization 6/24/2008 76 Male 119 lb 3/20/2009 Physician Japan
Primary
Concomitant
Anaemia Hospitalization 12/6/2007 Female 151 lb 3/30/2009 Physician Hungary
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 9/22/2008 82 5/12/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Pulmonary Congestion Other Serious 65 Male 154 lb 6/17/2009 Portugal
Primary
Concomitant
Pulmonary Congestion Other Serious 65 Male 157 lb 6/25/2009 Physician Portugal
Primary
Concomitant
Vision Blurred Other Serious 5/1/2002 47 Female 255 lb 7/23/2009 United States
Primary
Secondary
Concomitant
Toxic Skin Eruption Other Serious 6/1/2009 Male 8/12/2009 Portugal
Primary
Concomitant
Incorrect Storage Of Drug Hospitalization 1/1/2009 Female 128 lb 8/6/2009 Consumer United States
Primary
Concomitant
Sudden Cardiac Death Death 79 Male 8/18/2009 Germany
Primary
Concomitant
Toxic Skin Eruption Other Serious 6/1/2009 Male 8/28/2009 Portugal
Primary
Concomitant
Troponin Increased Other Serious 10/1/2008 Female 154 lb 10/12/2009 Consumer Ireland
Primary
Concomitant
Acute Coronary Syndrome Hospitalization 4/22/2008 55 10/8/2009 Physician Netherlands
Primary
Concomitant
Scar Hospitalization 6/24/2009 Female 128 lb 10/9/2009 Consumer United States
Primary
Concomitant
Oxygen Saturation Decreased Other Serious 9/17/2009 74 Male 11/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Violence-related Symptom Other Serious 10/3/2009 79 Male 11/18/2009 United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Other Serious 10/30/2009 80 Female 147 lb 12/8/2009 Other Health Professional United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 64 Male 12/1/2009 Lawyer United States
Primary
Concomitant
Weight Decreased 9/1/2009 58 Male 12/11/2009 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 64 Male 1/8/2010 United States
Primary
Concomitant
Poor Quality Drug Administered Other Serious 1/1/2010 Male 1/22/2010 Consumer United States
Primary
Concomitant
Rhabdomyolysis Other Serious 1/1/2008 2/5/2010 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 4/1/2008 85 Female 117 lb 2/8/2010
Primary
Concomitant
Poor Quality Drug Administered Hospitalization 1/1/2010 Male 2/16/2010 Physician United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2007 58 Male 137 lb 3/4/2010 Lawyer United States
Primary
Concomitant
Renal Failure Acute Other Serious 12/26/2007 79 Male 3/16/2010 Lawyer United States
Primary
Concomitant
Acute Coronary Syndrome Hospitalization 4/22/2008 55 Male 4/20/2010 Physician Netherlands
Primary
Concomitant
Renal Failure Acute Other Serious 12/1/2007 79 Male 205 lb 4/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Life Threatening 1/9/2010 70 Female 5/10/2010 Netherlands
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 1/9/2010 70 Female 5/21/2010 Physician Netherlands
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 12/1/2007 79 Male 205 lb 5/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2007 58 Male 137 lb 5/28/2010 Physician United States
Primary
Secondary
Concomitant
Tongue Discolouration Hospitalization 5/3/2010 74 Female 121 lb 6/30/2010 Consumer United States
Primary
Concomitant
Confusional State Hospitalization 7/6/2006 74 Male 170 lb 7/5/2010 Physician Netherlands
Primary
Concomitant
Mental Status Changes Hospitalization 7/28/2007 56 Female 7/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Other Serious 2/18/2008 66 Female 227 lb 7/16/2010 Physician United Kingdom
Primary
Concomitant
Acute Coronary Syndrome Hospitalization 4/22/2008 55 Male 8/4/2010 Physician Netherlands
Primary
Concomitant
Wheezing Other Serious 2/18/2008 66 Female 227 lb 8/17/2010 Physician United Kingdom
Primary
Concomitant
Paraesthesia Other Serious 1/1/2010 75 Female 8/29/2010 Consumer United States
Primary
Concomitant
Torsade De Pointes Life Threatening 82 Male 165 lb 8/30/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Interacting
Drug Hypersensitivity Other Serious 5/14/2010 46 Male 250 lb 8/31/2010 Physician United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2007 58 Male 137 lb 10/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Abnormal Dreams Other Serious 69 Male 11/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Abnormal Dreams Other Serious 69 Male 11/23/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Abnormal Dreams Other Serious 69 Male 11/23/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Abnormal Dreams Other Serious 69 Male 11/23/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Abnormal Dreams Other Serious 69 Male 11/23/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Abnormal Dreams Other Serious 11/26/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Abnormal Dreams Other Serious 69 Male 11/26/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Disability 1/1/2010 87 Female 119 lb 12/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Other Serious 2/21/2008 69 Female 150 lb 12/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Abnormal Dreams Other Serious 69 Male 11/19/2010 United Kingdom
Primary
Secondary
Abnormal Dreams Other Serious 69 Male 11/19/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Abnormal Dreams Other Serious 69 Male 11/18/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Abnormal Dreams Other Serious 69 Male 11/24/2010 United Kingdom
Primary
Secondary
Concomitant
Abnormal Dreams Other Serious 69 Male 11/23/2010 United Kingdom
Primary
Secondary
Concomitant
Abnormal Dreams Other Serious 69 Male 11/29/2010 Other Health Professional
Primary
Secondary
Concomitant
Myalgia Female 12/16/2010 Consumer United States
Primary
Concomitant
Hypertension Other Serious 10/22/2010 60 Male 414 lb 12/17/2010 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased 58 Male 12/21/2010 Consumer United States
Primary
Concomitant
Rib Fracture Other Serious 8/6/2010 81 Female 1/5/2011 Consumer United States
Primary
Concomitant
Oedema Peripheral Other Serious 1/1/2010 87 Female 119 lb 1/26/2011 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Oedema Hospitalization 1/7/2011 60 Female 180 lb 1/21/2011 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Other Serious Male 161 lb 1/28/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Sinus Tachycardia Other Serious 2/21/2008 69 Female 150 lb 1/31/2011 Pharmacist United States
Primary
Secondary
Concomitant
Death Death 11/6/2010 72 Male 289 lb 2/15/2011 Physician United States
Primary
Concomitant
Gastrointestinal Perforation Hospitalization 7/14/2010 73 Male 249 lb 2/15/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Potassium Decreased Other Serious 3/1/2008 81 Male 207 lb 2/28/2011 Other Health Professional United States
Primary
Concomitant
Pain Death 7/27/2010 Female 3/4/2011 Other Health Professional China
Primary
Concomitant
Chest Pain Hospitalization 4/1/2010 80 Female 106 lb 3/13/2011 Consumer Netherlands
Primary
Concomitant
Vomiting Life Threatening 1/11/2011 76 Male 3/9/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 1/13/2011 76 Male 3/9/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Vomiting Life Threatening 1/11/2011 76 Male 4/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/13/2011 76 Male 4/4/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Neutropenia Hospitalization 12/1/2010 81 Male 4/15/2011 Physician Greece
Primary
Secondary
Concomitant
Fatigue Hospitalization 1/9/2011 81 Male 4/18/2011 Physician Greece
Primary
Secondary
Concomitant
Confusional State Other Serious 11/1/2007 58 Male 137 lb 4/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Dizziness Hospitalization 61 Male 3/31/2011 Consumer United States
Primary
Concomitant
Depression Death 69 Female 4/20/2011 Other Health Professional Netherlands
Primary
Secondary
Radiotherapy Other Serious 78 Female 157 lb 4/22/2011 Other Health Professional United States
Primary
Concomitant
Hypotension Other Serious 8/20/2010 73 Male 4/28/2011 Other Health Professional Ireland
Primary
Secondary
Concomitant
Diarrhoea Death 7/28/2010 82 Female 5/6/2011 Other Health Professional China
Primary
Concomitant
Diarrhoea Death 7/28/2010 82 Female 5/10/2011 Other Health Professional China
Primary
Concomitant
Dyspnoea Hospitalization 4/1/2010 80 Female 106 lb 5/25/2011 Consumer Netherlands
Primary
Concomitant
Anaemia Other Serious Male 183 lb 5/27/2011 Other Health Professional United States
Primary
Concomitant
Blood Glucose Increased Other Serious 8/1/2010 80 Female 165 lb 6/14/2011 Consumer United States
Primary
Secondary
Concomitant
Stent Placement Other Serious 1/11/2011 54 Male 132 lb 6/17/2011 Consumer Mexico
Primary
Secondary
Haematuria Hospitalization 6/11/2011 55 Female 238 lb 6/17/2011 Pharmacist United States
Primary
Secondary
Concomitant
Heart Valve Calcification Disability 78 Female 157 lb 7/18/2011 Consumer United States
Primary
Concomitant
Disability Hospitalization 1/1/2008 49 Male 7/26/2011 Lawyer United States
Primary
Concomitant
Syncope Hospitalization 6/1/2011 78 Female 157 lb 8/9/2011 United States
Primary
Concomitant
International Normalised Ratio Increased Death 79 Male 8/11/2011 Physician United States
Primary
Concomitant
Death Hospitalization 69 Male 8/19/2011 Lawyer United States
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 10/6/2009 69 Male 8/26/2011 Physician United States
Primary
Secondary
Concomitant
Nausea Other Serious Male 8/30/2011 United States
Primary
Concomitant
Interacting
Lung Neoplasm Hospitalization 7/5/2011 79 Male 208 lb 9/2/2011 Physician United States
Primary
Concomitant
Malaise Other Serious Male 9/2/2011 Consumer United States
Primary
Concomitant
Interacting
Cardiac Disorder Other Serious Male 9/14/2011 Physician United States
Primary
Concomitant
Interacting
Cough Hospitalization 83 Male 9/29/2011 Physician Canada
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 4/2/2010 89 Female 10/10/2011 Other Health Professional United States
Primary
Concomitant
Anaemia Other Serious 11/1/2007 58 Male 137 lb 10/17/2011 Lawyer United States
Primary
Secondary
Concomitant
Drug Intolerance Other Serious 8/1/2011 84 Male 145 lb 10/21/2011 Physician United States
Primary
Concomitant

Drug Data