Isosorbide Mononitrate combined with Plavix

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Syncope Other Serious 5/16/2000 52 Female 201 lb 1/4/2006 Physician United States
Primary
Concomitant
Rectal Polyp Hospitalization 8/14/2005 64 Female 154 lb 12/30/2005 Physician United States
Primary
Concomitant
Muscle Disorder Hospitalization 12/25/2005 71 Male 1/11/2006 Consumer United States
Primary
Concomitant
Pericarditis Other Serious 1/1/2005 Male 237 lb 1/11/2006 Physician United States
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Other Serious 5/9/2002 80 Female 126 lb 1/12/2006 Physician United States
Primary
Concomitant
Speech Disorder Other Serious 12/12/2005 Female 176 lb 1/12/2006 Physician China
Primary
Concomitant
Visual Acuity Reduced Other Serious 79 Male 1/12/2006 Consumer United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 3/15/2000 56 Male 265 lb 1/19/2006 Physician United States
Primary
Concomitant
Rectal Polyp Hospitalization 8/14/2005 64 Female 154 lb 1/20/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Other Serious 6/1/2001 80 Female 146 lb 1/30/2006 Lawyer United States
Primary
Concomitant
Rash 5/1/2005 64 Female 324 lb 1/30/2006 Consumer United States
Primary
Secondary
Concomitant
Ischaemic Stroke Hospitalization 9/1/2004 77 Female 190 lb 2/16/2006 Physician United States
Primary
Concomitant
Nasopharyngitis Hospitalization 7/9/1999 77 Female 2/23/2006 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/1997 Male 3/2/2006 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2000 57 Female 150 lb 3/3/2006 Lawyer United States
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 1/1/1999 73 Female 165 lb 3/6/2006 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 11/1/2003 77 Male 3/1/2006 France
Primary
Concomitant
Weight Decreased Other Serious 5/25/2001 80 Female 126 lb 3/15/2006 Physician United States
Primary
Concomitant
Contusion Hospitalization 3/17/2004 53 Female 190 lb 12/27/2005 Consumer United States
Primary
Concomitant
Skin Discolouration Hospitalization 2/1/2004 42 Female 140 lb 12/27/2005 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 10/1/2004 94 Female 103 lb 12/27/2005 Consumer United States
Primary
Concomitant
Coronary Artery Occlusion Hospitalization 1/1/2003 67 Female 230 lb 12/27/2005 Other Health Professional United States
Primary
Concomitant
Sepsis Hospitalization 10/26/2004 79 Male 175 lb 12/29/2005 Consumer United States
Primary
Secondary
Concomitant
Traumatic Intracranial Haemorrhage Death 10/1/2005 95 Male 12/27/2005 United States
Primary
Concomitant
Nausea Other Serious 9/1/2005 76 Male 173 lb 12/27/2005 Consumer United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 10/1/2005 79 Male 210 lb 12/27/2005 Consumer United States
Primary
Concomitant
Haemorrhage Other Serious 5/1/2004 Female 12/21/2005 Consumer United States
Primary
Concomitant
Swelling Face Other Serious 3/20/2005 72 Male 278 lb 12/21/2005 Consumer United States
Primary
Concomitant
Rash Pruritic Other Serious 1/30/2005 75 Female 165 lb 12/21/2005 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 7/1/2004 80 Male 190 lb 12/21/2005 Physician United States
Primary
Concomitant
Coronary Artery Disease Death 12/1/2003 72 Male 3/28/2006 Physician United States
Primary
Concomitant
Intestinal Functional Disorder Hospitalization 7/18/2003 79 Female 3/28/2006 Lawyer United States
Primary
Concomitant
Intestinal Functional Disorder Hospitalization 7/18/2003 79 Female 4/3/2006 Lawyer United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 3/11/2006 72 Male 4/12/2006 Consumer United States
Primary
Concomitant
Road Traffic Accident Hospitalization 6/23/2002 72 Male 192 lb 4/20/2006 Lawyer United States
Primary
Concomitant
Road Traffic Accident Hospitalization 6/23/2002 72 Male 192 lb 4/26/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 5/25/2001 80 Female 126 lb 5/1/2006 Physician United States
Primary
Concomitant
Rhinitis Allergic Hospitalization 4/1/2003 49 Male 218 lb 5/5/2006 Physician United States
Primary
Concomitant
Dizziness Hospitalization 2/23/2006 89 Male 5/9/2006 Other Health Professional Ireland
Primary
Secondary
Concomitant
Drug Effect Decreased 10/1/2005 63 Male 240 lb 4/3/2006 Consumer United States
Primary
Concomitant
Respiratory Arrest Hospitalization 5/12/2006 Female 175 lb 6/8/2006 Consumer
Primary
Concomitant
Haematochezia Hospitalization 4/9/2005 Male 134 lb 6/28/2006 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Macular Oedema 10/1/2005 74 Male 5/19/2006 Physician United States
Primary
Concomitant
Haematochezia Hospitalization 4/7/2005 Male 134 lb 7/17/2006 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/1/2005 57 Female 7/19/2006 Consumer United States
Primary
Concomitant
Pericarditis Other Serious 1/1/2005 Male 237 lb 8/25/2006 Physician United States
Primary
Secondary
Concomitant
Pyelonephritis Hospitalization 7/20/2006 81 Female 93 lb 8/29/2006 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 7/20/2006 81 Female 93 lb 9/12/2006 Physician Japan
Primary
Concomitant
Myocardial Infarction Death 6/27/2006 65 Male 147 lb 9/14/2006 Other Health Professional United States
Primary
Concomitant
Speech Disorder Other Serious 12/12/2005 Female 176 lb 10/2/2006 Physician China
Primary
Concomitant
Tongue Oedema Other Serious 62 Male 9/28/2006 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2006 62 Male 224 lb 9/29/2006 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 7/20/2006 81 Female 93 lb 10/17/2006 Physician Japan
Primary
Concomitant
Sleep Disorder Other Serious 8/21/2006 61 Female 10/11/2006 United States
Primary
Secondary
Concomitant
Pyelonephritis Hospitalization 7/20/2006 81 Female 93 lb 10/25/2006 Physician Japan
Primary
Concomitant
Sleep Disorder Hospitalization 3/1/2006 Male 11/20/2006 Consumer United States
Primary
Secondary
Concomitant
Death Death 10/17/2006 71 Male 11/17/2006 Other Health Professional United States
Primary
Concomitant
Melaena Other Serious 3/15/1999 72 Male 169 lb 11/17/2006 Consumer United States
Primary
Secondary
Concomitant
Injection Site Pain 5/1/2006 Female 12/20/2006 Pharmacist United States
Primary
Concomitant
Transaminases Increased Other Serious 11/9/2006 Female 108 lb 1/3/2007 Physician Japan
Primary
Concomitant
Tremor 1/1/2006 78 Male 233 lb 10/19/2006 United States
Primary
Concomitant
Pericardial Effusion Hospitalization 1/1/2006 Male 165 lb 1/17/2007 Consumer United States
Primary
Concomitant
Tremor Hospitalization 11/1/2006 70 Male 3/8/2007 Consumer United States
Primary
Concomitant
Renal Disorder Hospitalization 2/16/2007 51 Female 3/12/2007 Consumer United States
Primary
Concomitant
Renal Failure Chronic Other Serious 3/12/2007 Male 190 lb 3/27/2007 Consumer United States
Primary
Concomitant
Fatigue 1/1/2006 83 Male 210 lb 11/7/2006 Physician United States
Primary
Concomitant
Low Density Lipoprotein Decreased Other Serious 62 Male 11/28/2006 United States
Primary
Concomitant
Sepsis Other Serious 1/1/2001 Male 4/5/2007 Consumer United States
Primary
Secondary
Concomitant
Dyspepsia Hospitalization 3/26/2007 Female 198 lb 4/5/2007 United States
Primary
Secondary
Concomitant
Vomiting Death 1/1/2007 77 Female 4/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tremor Hospitalization 11/1/2006 70 Male 4/27/2007 Consumer United States
Primary
Concomitant
Renal Disorder Hospitalization 2/16/2007 51 Female 4/27/2007 Consumer United States
Primary
Concomitant
Rhabdomyolysis Other Serious 8/28/2006 72 Male 2/21/2007 United States
Primary
Concomitant
Drug Ineffective Hospitalization 3/4/2006 56 Female 120 lb 12/13/2006 Pharmacist United States
Primary
Concomitant
Coronary Artery Occlusion Other Serious 1/1/2004 59 Male 205 lb 12/13/2006 Consumer United States
Primary
Concomitant
Diverticulum Intestinal Haemorrhagic Hospitalization 2/28/2006 80 Male 12/13/2006 Physician United States
Primary
Concomitant
Medication Residue Other Serious 3/29/2005 75 Male 12/13/2006 Consumer United States
Primary
Secondary
Concomitant
Syncope Hospitalization 5/1/2006 82 Male 140 lb 12/13/2006 United States
Primary
Concomitant
Proteinuria Other Serious 5/26/2006 70 Male 190 lb 12/13/2006 Physician United States
Primary
Concomitant
Contusion Hospitalization 8/7/2006 89 Female 123 lb 12/13/2006 Consumer United States
Primary
Concomitant
Suicidal Ideation 10/27/2006 41 Male 2/28/2007 Other Health Professional United States
Primary
Concomitant
Pericardial Effusion Hospitalization 1/1/2006 Male 165 lb 6/26/2007 Consumer United States
Primary
Concomitant
Hypoglycaemia Other Serious 12/4/2006 58 Male 201 lb 4/26/2007 Physician United States
Primary
Concomitant
Treatment Noncompliance Other Serious 6/20/2007 65 Male 7/3/2007 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 8/12/2000 Female 146 lb 7/24/2007 Lawyer United States
Primary
Secondary
Concomitant
Tremor Other Serious 1/1/2006 71 Female 7/20/2007 Consumer United States
Primary
Secondary
Concomitant
Haemoptysis Other Serious 5/1/2007 Male 276 lb 7/25/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Death 6/25/2007 Male 118 lb 8/1/2007 Other Health Professional United States
Primary
Concomitant
Hypotension Hospitalization 7/6/2007 50 Male 8/16/2007 Physician Philippines
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2006 53 Female 297 lb 8/13/2007 Consumer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 6/1/2005 42 Male 8/23/2007 Physician Spain
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 6/1/2005 42 Male 8/30/2007 Physician Spain
Primary
Secondary
Concomitant
Hypotension Hospitalization 7/6/2007 50 Male 9/4/2007 Other Health Professional Philippines
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 10/8/2006 78 Female 9/7/2007 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 57 Female 147 lb 9/12/2007 Consumer United States
Primary
Concomitant
Pain In Jaw Other Serious 7/1/2006 66 Female 162 lb 9/12/2007 Physician United States
Primary
Secondary
Concomitant
Nausea Hospitalization 7/1/2007 79 Female 9/6/2007 Consumer United States
Primary
Secondary
Concomitant
Hypothyroidism 83 Female 10/1/2007 United States
Primary
Concomitant
Mental Status Changes Hospitalization 7/28/2007 56 Female 9/28/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Reflux Oesophagitis Hospitalization 9/10/2007 67 Male 174 lb 10/3/2007 Physician Malaysia
Primary
Secondary
Concomitant
Angina Unstable Hospitalization 5/12/2006 65 Male 8/6/2007 Physician United States
Primary
Concomitant
Reflux Oesophagitis Hospitalization 9/10/2007 67 Male 174 lb 10/11/2007 Physician Malaysia
Primary
Secondary
Concomitant
Thrombosis Hospitalization 1/1/2001 Male 155 lb 10/19/2007 Consumer United States
Primary
Secondary
Concomitant
Headache 8/12/2007 79 Male 10/24/2007 Consumer United States
Primary
Concomitant
Hypersensitivity Other Serious 62 Male 10/2/2007 United States
Primary
Secondary
Concomitant
Orthostatic Hypotension 73 Male 11/13/2007 Consumer United States
Primary
Concomitant
Throat Irritation 7/1/2006 58 Female 11/14/2007 Consumer United States
Primary
Concomitant
Tremor 10/30/2007 76 Male 11/21/2007 Consumer United States
Primary
Secondary
Concomitant
Tremor Other Serious 3/27/2002 44 Female 250 lb 11/26/2007 Physician United States
Primary
Concomitant
Weight Decreased 5/8/2007 76 Male 11/16/2007 Other Health Professional United States
Primary
Concomitant
Pain In Extremity 75 Male 11/16/2007 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Death 6/25/2007 Male 118 lb 1/16/2008 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 12/11/2007 Female 1/24/2008 Physician United States
Primary
Secondary
Concomitant
Kidney Infection Hospitalization 1/1/2007 Male 1/25/2008 Other Health Professional Australia
Primary
Concomitant
Mental Status Changes Hospitalization 7/28/2007 56 Female 1/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Osteoarthritis Other Serious 12/1/2007 Female 2/6/2008 Physician United States
Primary
Concomitant
Cerebral Haemorrhage Hospitalization 1/31/2003 82 Male 11/30/2007 Consumer United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Hospitalization 56 Female 2/7/2008 Other Health Professional United States
Primary
Concomitant
Interacting
Cough Other Serious 1/12/2007 57 Male 223 lb 11/29/2007 Consumer United States
Primary
Concomitant
Haematoma Hospitalization 1/1/2006 79 Female 167 lb 11/29/2007 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 12/1/2006 57 Female 220 lb 11/29/2007 Consumer United States
Primary
Concomitant
Small Intestinal Haemorrhage Other Serious 10/1/2006 83 Male 11/29/2007 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2003 60 Male 290 lb 11/29/2007 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 9/1/2007 Male 114 lb 12/5/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2006 73 Male 120 lb 12/3/2007 Consumer United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 2/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hypotension Other Serious 7/6/2007 50 Male 2/15/2008 Physician Philippines
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 56 Female 2/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Epistaxis Life Threatening 1/1/2007 76 Male 186 lb 2/20/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Blood Glucose Increased Hospitalization 1/14/2008 72 Female 143 lb 2/22/2008 Consumer Turkey
Primary
Concomitant
Death Death 8/14/2007 68 Male 112 lb 2/25/2008 Physician United States
Primary
Concomitant
Rhabdomyolysis Other Serious 8/9/2006 72 Male 158 lb 2/21/2008 Pharmacist United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 12/11/2007 Female 3/21/2008 Physician United States
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 66 Male 4/4/2008 Consumer United States
Primary
Concomitant
Mental Status Changes Hospitalization 56 Female 4/7/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Hospitalization Female 150 lb 4/14/2008 United States
Primary
Concomitant
Hypotension Other Serious 7/6/2007 Male 4/21/2008 Philippines
Primary
Secondary
Concomitant
Tremor Hospitalization 4/25/2008 Female 113 lb 4/28/2008 Pharmacist United States
Primary
Concomitant
Urinary Retention Other Serious 2/1/2008 Female 137 lb 4/30/2008 Consumer United States
Primary
Concomitant
Coronary Artery Occlusion Hospitalization 4/1/2008 73 Female 5/15/2008 Consumer United States
Primary
Secondary
Concomitant
Blood Glucose Increased Other Serious 5/15/2008 Female 140 lb 5/30/2008 Consumer United States
Primary
Concomitant
Skin Laceration Hospitalization 5/1/2008 76 Male 195 lb 5/20/2008 United States
Primary
Secondary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Hospitalization Female 150 lb 5/22/2008 United States
Primary
Concomitant
Tremor Hospitalization 4/20/2008 Female 112 lb 6/9/2008 Pharmacist United States
Primary
Concomitant
Tendon Rupture Hospitalization 3/1/2008 75 Male 165 lb 6/17/2008 Pharmacist China
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 6/1/2006 53 Male 217 lb 6/18/2008 Other Health Professional United States
Primary
Concomitant
Vision Blurred 12/1/2007 78 Female 145 lb 6/19/2008 United States
Primary
Concomitant
Tendon Rupture Hospitalization 3/1/2008 75 Male 165 lb 6/23/2008 Pharmacist China
Primary
Concomitant
Therapeutic Response Unexpected 1/1/2008 72 Male 5/6/2008 United States
Primary
Concomitant
Pancytopenia Disability 5/6/2008 Female 7/24/2008 Physician Finland
Primary
Concomitant

Drug Data