Isosorbide Mononitrate combined with Norvasc

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rectal Polyp Hospitalization 8/14/2005 64 Female 154 lb 12/30/2005 Physician United States
Primary
Concomitant
Subarachnoid Haemorrhage Other Serious 5/9/2002 80 Female 126 lb 1/12/2006 Physician United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 79 Male 1/12/2006 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 1/1/2003 76 Female 201 lb 1/19/2006 Lawyer United States
Primary
Concomitant
Vitamin B12 Deficiency Hospitalization 1/1/2003 76 Female 201 lb 1/23/2006 Physician United States
Primary
Concomitant
Rectal Polyp Hospitalization 8/14/2005 64 Female 154 lb 1/20/2006 Physician United States
Primary
Concomitant
Respiration Abnormal Hospitalization 8/19/2005 Male 2/2/2006 Other Health Professional Sweden
Primary
Concomitant
Cerebral Infarction Hospitalization 7/1/2005 62 Male 2/3/2006 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 8/8/2002 59 Male 203 lb 2/13/2006 Physician United States
Primary
Concomitant
Nasopharyngitis Hospitalization 7/9/1999 77 Female 2/23/2006 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/1997 Male 3/2/2006 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 11/1/2003 89 Female 141 lb 3/3/2006 Physician United States
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 1/1/1999 73 Female 165 lb 3/6/2006 Lawyer United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 2/8/2006 70 Female 3/10/2006 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 2/1/2006 75 Female 3/6/2006 Pharmacist Japan
Primary
Concomitant
Vertebral Artery Stenosis Other Serious 2/1/2001 60 Female 3/14/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 5/25/2001 80 Female 126 lb 3/15/2006 Physician United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 2/1/2006 70 Female 3/15/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 2/1/2006 70 Female 3/15/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 12/8/2003 66 Female 181 lb 3/23/2006 Lawyer United States
Primary
Concomitant
Intestinal Functional Disorder Hospitalization 7/18/2003 79 Female 3/28/2006 Lawyer United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 1/1/2001 64 Male 198 lb 3/30/2006 Physician United States
Primary
Concomitant
Intestinal Functional Disorder Hospitalization 7/18/2003 79 Female 4/3/2006 Lawyer United States
Primary
Concomitant
Tinnitus Hospitalization 2/1/2001 60 Female 161 lb 4/4/2006 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 1/1/2005 Male 200 lb 4/10/2006 Consumer United States
Primary
Concomitant
Xeroderma Hospitalization 1/1/2005 75 Male 155 lb 4/3/2006 Physician United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 2/1/2001 60 Female 161 lb 4/14/2006 Physician United States
Primary
Concomitant
Oedema Peripheral Other Serious 12/8/2003 66 Female 181 lb 4/17/2006 Lawyer United States
Primary
Concomitant
Vitamin B12 Deficiency Hospitalization 1/1/2003 76 Female 201 lb 4/20/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Death 4/24/2004 67 Male 165 lb 4/24/2006 Physician United States
Primary
Concomitant
Vitamin B12 Deficiency Hospitalization 1/1/2003 76 Female 201 lb 4/27/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 5/25/2001 80 Female 126 lb 5/1/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 9/29/2000 60 Female 181 lb 5/3/2006 Physician United States
Primary
Concomitant
Thrombotic Stroke Hospitalization 7/1/2005 62 Male 6/16/2006 Physician Japan
Primary
Concomitant
Cholestasis Life Threatening 5/23/2006 77 Male 6/12/2006 Physician Japan
Primary
Concomitant
Macular Oedema 10/1/2005 74 Male 5/19/2006 Physician United States
Primary
Concomitant
Renal Failure Acute Life Threatening 7/4/2006 Male 117 lb 7/26/2006 Physician Japan
Primary
Concomitant
Tongue Oedema Other Serious 3/15/2006 87 Female 6/21/2006 United States
Primary
Concomitant
Yellow Skin Hospitalization 8/15/2005 72 Male 165 lb 7/25/2006 Japan
Primary
Secondary
Liver Disorder Hospitalization 8/15/2005 72 Male 165 lb 8/2/2006 Physician Japan
Primary
Secondary
Sudden Death Death 7/19/2005 79 Male 8/15/2006 Physician Japan
Primary
Concomitant
Erythema Multiforme Other Serious 1/19/2006 83 Female 8/15/2006 Physician Japan
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 1/10/2006 90 Male 8/11/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Lymphoma Life Threatening 8/1/2006 69 Male 253 lb 8/16/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Life Threatening 7/4/2006 Male 117 lb 8/30/2006 Physician Japan
Primary
Concomitant
Urine Glucose False Positive Other Serious 4/24/2006 65 Male 150 lb 8/28/2006 Other Health Professional Japan
Primary
Concomitant
Drug Interaction Other Serious 7/22/2006 74 Male 9/1/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Drug Interaction Other Serious 7/22/2006 74 Male 9/1/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Sudden Death Death 7/19/2005 79 Male 6/14/2006 Physician Japan
Primary
Concomitant
Dyspnoea Hospitalization 3/7/2005 79 Female 9/15/2006 Consumer Japan
Primary
Concomitant
Myocardial Infarction Death 6/27/2006 65 Male 147 lb 9/14/2006 Other Health Professional United States
Primary
Concomitant
Rash Other Serious 1/19/2006 83 Female 150 lb 10/14/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 9/21/2006 77 Male 130 lb 10/16/2006 Physician Japan
Primary
Concomitant
Renal Failure Acute Life Threatening 9/21/2006 77 Male 130 lb 10/26/2006 Physician Japan
Primary
Concomitant
Renal Failure Acute Life Threatening 7/4/2006 Male 117 lb 11/29/2006 Physician Japan
Primary
Concomitant
Death Death 83 Female 11/22/2006 Consumer United States
Primary
Concomitant
Visual Disturbance Hospitalization Female 1/4/2007 Consumer United States
Primary
Concomitant
Sinus Disorder Hospitalization 1/1/2002 70 Female 8/23/2006 United States
Primary
Concomitant
Pulmonary Oedema Other Serious 1/1/2003 81 Female 2/27/2007 Consumer United States
Primary
Concomitant
Therapeutic Response Unexpected 67 Female 3/7/2007 Consumer United States
Primary
Concomitant
Refusal Of Treatment By Patient Other Serious 1/1/2003 81 Female 100 lb 3/22/2007 Physician United States
Primary
Concomitant
Refusal Of Treatment By Patient Other Serious 1/1/2003 81 Female 100 lb 4/9/2007 Physician United States
Primary
Concomitant
Renal Cell Carcinoma Stage Unspecified Other Serious 1/1/2003 81 Female 100 lb 4/9/2007 Physician United States
Primary
Concomitant
Shoulder Operation Other Serious 1/1/2006 Female 141 lb 4/27/2007 Consumer United States
Primary
Secondary
Concomitant
Therapeutic Response Unexpected 1/1/2007 78 Female 5/17/2007 Other Health Professional United States
Primary
Concomitant
Shoulder Operation Other Serious 1/1/2006 Female 141 lb 6/29/2007 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 8/12/2000 Female 146 lb 7/24/2007 Lawyer United States
Primary
Secondary
Concomitant
Swelling Face Other Serious 6/1/2007 57 Male 7/30/2007 Pharmacist Canada
Primary
Concomitant
Swelling Face Other Serious 6/1/2007 57 Male 8/3/2007 Pharmacist Canada
Primary
Concomitant
Weight Increased Other Serious 7/1/2007 Female 115 lb 9/11/2007 United States
Primary
Secondary
Concomitant
Therapeutic Response Unexpected 1/1/2007 78 Female 8/16/2007 Other Health Professional United States
Primary
Concomitant
Urinary Incontinence Hospitalization 7/19/2007 72 Male 10/5/2007 Consumer United States
Primary
Concomitant
Syncope Hospitalization 3/1/2008 63 Male 4/3/2008 Physician Japan
Primary
Concomitant
Muscle Injury Other Serious 3/20/2008 74 Female 4/2/2008 Consumer United States
Primary
Concomitant
Syncope Hospitalization 3/14/2008 65 Male 4/15/2008 Physician Japan
Primary
Concomitant
Syncope Hospitalization 3/14/2008 64 Male 4/18/2008 Physician Japan
Primary
Concomitant
Muscle Injury Other Serious 3/20/2008 74 Female 152 lb 5/2/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious Female 3/27/2008 Consumer United States
Primary
Concomitant
Weight Decreased 12/1/2007 62 Female 132 lb 7/7/2008 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 7/1/2008 54 Female 145 lb 12/4/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 6/1/2008 76 Female 125 lb 12/10/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 10/25/2008 46 Female 180 lb 12/15/2008 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 8/4/2008 77 Female 155 lb 12/18/2008 Consumer United States
Primary
Concomitant
Dyspepsia 2/1/2008 69 Female 265 lb 1/5/2009 Consumer United States
Primary
Secondary
Concomitant
Product Quality Issue Hospitalization 10/3/2008 75 Female 1/6/2009 Consumer United States
Primary
Concomitant
Rib Fracture Death 4/1/2008 84 Female 119 lb 2/3/2009 Consumer United States
Primary
Concomitant
Product Quality Issue Death 9/11/2008 67 Male 2/23/2009 Consumer United States
Primary
Concomitant
Drug Interaction Hospitalization 7/29/2007 80 Male 4/8/2009 Other Health Professional France
Primary
Concomitant
Interacting
Dry Mouth 2/1/2009 Male 4/22/2009 Consumer
Primary
Concomitant
Renal Failure Death 1/12/2008 69 Female 139 lb 5/15/2009 Physician Japan
Primary
Concomitant
Renal Failure Death 1/12/2008 69 Female 139 lb 6/1/2009 Physician Japan
Primary
Concomitant
Procedural Complication 6/20/2009 71 Male 7/2/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Pericarditis 6/20/2009 71 Male 7/23/2009 Japan
Primary
Concomitant
Procedural Complication Life Threatening 6/19/2009 71 Male 8/21/2009 Japan
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 3/10/1998 54 Male 209 lb 9/23/2009 United States
Primary
Concomitant
Hot Flush 4/1/2009 Male 10/8/2009 United States
Primary
Concomitant
Skin Discolouration Hospitalization 10/1/2009 Male 200 lb 11/19/2009 Consumer United States
Primary
Concomitant
Yellow Skin Hospitalization 10/1/2009 Male 200 lb 11/20/2009 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 64 Male 11/18/2009 United States
Primary
Concomitant
Toxic Skin Eruption Other Serious 9/4/2009 50 12/2/2009 Physician Japan
Primary
Concomitant
Visual Acuity Reduced Other Serious 64 Male 12/1/2009 Lawyer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 6/4/2009 87 Male 12/14/2009 Physician Switzerland
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 11/1/2008 77 Male 260 lb 12/10/2009 United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 64 Male 1/8/2010 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 65 Male 1/12/2010 United States
Primary
Concomitant
Weight Increased Hospitalization 11/1/2008 51 Male 210 lb 1/20/2010 Consumer United States
Primary
Concomitant
Vascular Graft Other Serious 1/1/1996 Male 206 lb 1/29/2010 Consumer United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 6/4/2009 Male 2/4/2010 Physician Switzerland
Primary
Concomitant
Vascular Graft Other Serious 1/1/1996 69 Male 206 lb 4/13/2010 Consumer United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 8/24/2007 Female 4/22/2010 United States
Primary
Concomitant
Spinal Column Stenosis Disability 1/11/2010 60 Male 4/22/2010 Other Health Professional Japan
Primary
Concomitant
Visual Acuity Reduced Other Serious 6/4/2009 87 Male 6/1/2010 Physician Switzerland
Primary
Concomitant
Stent Placement Other Serious 12/14/2007 82 Male 130 lb 6/14/2010 Physician Japan
Primary
Concomitant
Tobacco User 10/1/2006 53 Male 178 lb 7/8/2010 Consumer United States
Primary
Concomitant
Flatulence 2/1/2007 66 Male 148 lb 7/9/2010 Consumer United States
Primary
Concomitant
Nausea 2/21/2007 65 Female 168 lb 7/12/2010 Other Health Professional United States
Primary
Concomitant
Nightmare 3/19/2007 70 Female 149 lb 7/12/2010 Consumer United States
Primary
Concomitant
Insomnia 7/14/2007 75 Male 150 lb 7/14/2010 Consumer United States
Primary
Concomitant
Malaise Other Serious 9/1/2007 67 Male 7/15/2010 Other Health Professional United States
Primary
Concomitant
Stent Placement Other Serious 12/14/2007 82 Male 130 lb 8/4/2010 Physician Japan
Primary
Concomitant
Pharyngeal Oedema Other Serious Female 10/19/2010 United States
Primary
Concomitant
Skin Ulcer Other Serious 10/23/2007 63 Female 141 lb 10/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 2/10/2004 60 Female 141 lb 11/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatitis Cholestatic Hospitalization 7/12/2010 82 Male 163 lb 11/12/2010 Physician Spain
Primary
Interacting
Hepatitis Cholestatic Hospitalization 7/12/2010 82 Male 11/22/2010 Other Health Professional Spain
Primary
Secondary
Drug Interaction Hospitalization 7/1/2010 82 Male 11/17/2010 Physician Spain
Primary
Secondary
Myalgia Female 12/16/2010 Consumer United States
Primary
Concomitant
Pain Other Serious 12/2/2007 50 Female 134 lb 2/8/2011 Lawyer United States
Primary
Concomitant
Confusional State Other Serious 11/18/2008 63 Female 130 lb 3/18/2011 Physician United States
Primary
Concomitant
Alopecia Other Serious 3/1/2006 66 Female 216 lb 4/7/2011 Consumer United States
Primary
Concomitant
Death Death 4/1/2003 56 Female 198 lb 4/7/2011 Lawyer United States
Primary
Concomitant
Flank Pain Hospitalization 68 Female 4/15/2011 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 4/9/2011 77 Female 93 lb 4/12/2011 Pharmacist United States
Primary
Concomitant
Pain Death 2/19/2007 75 Male 200 lb 4/16/2011 Other Health Professional United States
Primary
Concomitant
Dizziness Hospitalization 61 Male 3/31/2011 Consumer United States
Primary
Concomitant
Headache Other Serious 81 Female 4/25/2011 United States
Primary
Secondary
Concomitant
Unevaluable Event Death 67 Female 4/25/2011 Other Health Professional United States
Primary
Concomitant
Abdominal Pain Hospitalization 68 Female 4/29/2011 Physician United States
Primary
Concomitant
Renal Failure Death 4/1/2003 57 Female 198 lb 5/19/2011 Lawyer United States
Primary
Concomitant
Clostridium Difficile Colitis Hospitalization 1/31/2011 90 Female 123 lb 5/24/2011 Pharmacist Germany
Primary
Secondary
Concomitant
Fear Other Serious 3/10/2006 58 Male 301 lb 5/25/2011 Consumer United States
Primary
Concomitant
Angina Pectoris Hospitalization 8/4/2010 71 Male 134 lb 5/27/2011 Consumer Switzerland
Primary
Secondary
Concomitant
Dystonia Other Serious 7/1/2009 58 Female 175 lb 5/23/2011 Lawyer United States
Primary
Concomitant
Nerve Injury Other Serious 4/1/2009 59 Female 6/3/2011 Lawyer United States
Primary
Concomitant
Clostridium Difficile Colitis Death 1/31/2011 90 Female 123 lb 6/7/2011 Pharmacist Germany
Primary
Secondary
Concomitant
Renal Injury Other Serious 10/9/2005 67 Female 170 lb 6/7/2011 Other Health Professional United States
Primary
Concomitant
Renal Injury Other Serious 2/10/2005 83 Male 194 lb 6/10/2011 Other Health Professional United States
Primary
Concomitant
Rash Macular Other Serious 3/1/2006 66 Female 220 lb 6/28/2011 Consumer United States
Primary
Concomitant
Anhedonia Other Serious 1/1/2006 78 Male 300 lb 6/30/2011 Other Health Professional United States
Primary
Concomitant
Chorea Disability 1/1/2003 61 Female 6/22/2011 Physician United States
Primary
Concomitant

Drug Data