Isosorbide Mononitrate combined with Nitroglycerin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Respiratory Failure Hospitalization 2/23/2005 Female 121 lb 1/3/2006 Other Health Professional
Primary
Secondary
Concomitant
Interacting
Exercise Test Abnormal Hospitalization 6/7/2005 68 Male 1/5/2006 Physician United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2000 62 Female 187 lb 1/17/2006 Lawyer United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 11/30/2005 Male 153 lb 1/3/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 8/8/2002 59 Male 203 lb 2/13/2006 Physician United States
Primary
Concomitant
Dizziness Postural Hospitalization 10/12/2005 Male 144 lb 10/13/2005 Pharmacist United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 5/15/2003 76 Female 77 lb 2/21/2006 Lawyer United Kingdom
Primary
Concomitant
Vomiting Other Serious 8/1/2001 76 Female 99 lb 2/24/2006 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 7/12/2005 Female 2/28/2006 Consumer United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 3/14/2004 42 Female 105 lb 2/22/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 8/1/2001 76 Female 99 lb 3/2/2006 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 11/1/2003 89 Female 141 lb 3/3/2006 Physician United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 1/1/2005 76 Female 3/16/2006 Other Health Professional Italy
Primary
Concomitant
Rhabdomyolysis Hospitalization 1/1/2005 76 Female 3/23/2006 Other Health Professional Italy
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 1/1/2002 49 Male 209 lb 3/27/2006 Physician United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Inflammation Hospitalization 4/10/2002 60 Female 112 lb 3/29/2006 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 1/1/2005 76 Female 3/30/2006 Other Health Professional Italy
Primary
Concomitant
Sudden Death Death 1/6/2006 76 Male 172 lb 3/31/2006 Other Health Professional United Kingdom
Primary
Concomitant
Myalgia Other Serious 7/22/2005 51 Male 227 lb 4/13/2006 Pharmacist United States
Primary
Concomitant
Road Traffic Accident Hospitalization 6/23/2002 72 Male 192 lb 4/20/2006 Lawyer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2003 67 Female 121 lb 4/25/2006 Lawyer United States
Primary
Concomitant
Road Traffic Accident Hospitalization 6/23/2002 72 Male 192 lb 4/26/2006 Physician United States
Primary
Concomitant
Palpitations Other Serious 1/6/2006 47 Male 185 lb 3/10/2006 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Hospitalization 7/16/2004 81 Female 4/28/2006 Norway
Primary
Concomitant
Urinary Tract Infection Hospitalization 12/22/2005 87 Male 5/1/2006 Physician United Kingdom
Primary
Concomitant
Ventricular Fibrillation Other Serious 1/6/2006 76 Male 154 lb 5/22/2006 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Enterococcal Life Threatening 12/22/2005 87 Male 5/10/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 1/6/2006 77 Male 154 lb 5/23/2006 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Enterococcal Life Threatening 12/22/2005 87 Male 5/19/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 1/6/2006 76 Male 172 lb 5/26/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Required Intervention 1/11/2006 76 Male 118 lb 5/24/2006 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Life Threatening 12/22/2005 87 Male 5/26/2006 United Kingdom
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 1/6/2006 77 Male 154 lb 6/9/2006 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Enterococcal Life Threatening 12/22/2005 87 Male 6/7/2006 United Kingdom
Primary
Secondary
Concomitant
Hallucination Hospitalization 11/1/2001 74 Male 6/23/2006 Other Health Professional Sweden
Primary
Concomitant
Heart Rate Irregular Hospitalization 5/21/2006 64 Male 224 lb 5/23/2006 Pharmacist United States
Primary
Concomitant
Tachycardia 2/2/2006 Male 180 lb 8/4/2006 Physician United States
Primary
Concomitant
Ischaemic Stroke Life Threatening 5/29/2006 86 Female 8/25/2006 United Kingdom
Primary
Secondary
Concomitant
Angina Pectoris Other Serious 71 Male 8/25/2006 United Kingdom
Primary
Concomitant
Vascular Dementia Hospitalization 7/6/2006 74 Male 170 lb 9/15/2006 Physician Netherlands
Primary
Concomitant
Myocardial Infarction Death 8/10/2006 77 Male 9/22/2006 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Skin Oedema Hospitalization 76 Male 9/21/2006 Physician United Kingdom
Primary
Concomitant
Myocardial Infarction Death 8/10/2006 77 Male 10/18/2006 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Vomiting Required Intervention 8/7/2006 88 Male 169 lb 9/20/2006 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Required Intervention 8/23/2006 85 Male 160 lb 10/10/2006 Other Health Professional United States
Primary
Concomitant
Vascular Dementia Hospitalization 7/6/2006 74 Male 170 lb 10/17/2006 Physician Netherlands
Primary
Concomitant
Hypotension Hospitalization 7/12/2006 76 Male 118 lb 8/8/2006 Pharmacist United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 8/10/2006 75 Male 231 lb 11/21/2006 Pharmacist United States
Primary
Secondary
Concomitant
Visual Disturbance Hospitalization Female 1/4/2007 Consumer United States
Primary
Concomitant
Haemolytic Anaemia Hospitalization 9/21/2006 Male 150 lb 10/19/2006 Pharmacist United States
Primary
Concomitant
Myalgia Other Serious 11/20/2006 61 Male 170 lb 11/20/2006 Pharmacist United States
Primary
Concomitant
Rash Other Serious 8/23/2006 52 Male 329 lb 10/13/2006 Pharmacist United States
Primary
Concomitant
Rash Generalised Hospitalization 11/27/2006 Male 216 lb 12/22/2006 Pharmacist United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 11/13/2006 89 Male 121 lb 2/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vascular Dementia Hospitalization 7/6/2006 Male 170 lb 2/15/2007 Netherlands
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 9/13/2006 75 Male 231 lb 2/12/2007 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/25/2007 48 Male 214 lb 3/7/2007 Physician United States
Primary
Concomitant
Renal Failure Chronic Other Serious 3/12/2007 Male 190 lb 3/27/2007 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 3/15/2007 84 Female 3/30/2007 Physician United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 3/23/2007 72 Male 4/10/2007 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/25/2007 48 Male 214 lb 4/3/2007 Physician United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 3/23/2007 72 Male 4/16/2007 United Kingdom
Primary
Concomitant
Delirium Other Serious 3/13/2007 70 Male 169 lb 3/28/2007 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/25/2007 48 Male 214 lb 4/25/2007 Physician United States
Primary
Concomitant
Melaena Hospitalization 3/26/2007 77 Male 5/8/2007 Pharmacist United States
Primary
Secondary
Concomitant
Rash Hospitalization 4/28/2007 77 Male 5/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rash Hospitalization 4/28/2007 77 Male 183 lb 6/5/2007 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Tachycardia Hospitalization 5/23/2007 72 Male 6/4/2007 United Kingdom
Primary
Concomitant
Wound Dehiscence Hospitalization 6/4/2007 Male 170 lb 6/7/2007 United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 11/22/2006 50 Male 6/25/2007 Other Health Professional United States
Primary
Concomitant
Therapeutic Product Ineffective Hospitalization 78 Male 198 lb 7/16/2007
Primary
Secondary
Rash Required Intervention 7/9/2007 47 Female 188 lb 7/18/2007 Pharmacist United States
Primary
Concomitant
Pancytopenia Required Intervention 2/20/2007 80 Male 131 lb 6/20/2007 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 53 Female 297 lb 8/13/2007 Consumer United States
Primary
Concomitant
Blood Glucose Increased Hospitalization 7/17/2007 83 Male 8/17/2007 Consumer United States
Primary
Concomitant
Death Hospitalization 7/30/2007 Male 8/24/2007 Physician United States
Primary
Concomitant
Postinfarction Angina Death Male 158 lb 8/30/2007 Physician Canada
Primary
Concomitant
Muscle Spasticity Other Serious 1/1/2007 Female 177 lb 9/10/2007 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2006 57 Female 147 lb 9/12/2007 Consumer United States
Primary
Concomitant
Pain In Jaw Other Serious 7/1/2006 66 Female 162 lb 9/12/2007 Physician United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 7/28/2007 56 Female 9/28/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Angina Unstable Hospitalization 5/12/2006 65 Male 8/6/2007 Physician United States
Primary
Concomitant
Muscle Spasms Other Serious 1/1/2006 75 Female 192 lb 10/5/2007 Other Health Professional United States
Primary
Concomitant
Pneumonia Other Serious 5/2/2007 Female 10/8/2007 United States
Primary
Concomitant
Breath Odour 7/1/2007 Male 8/6/2007 Pharmacist United States
Primary
Concomitant
Ventricular Extrasystoles Life Threatening 7/18/2007 47 Female 126 lb 10/26/2007 Physician United States
Primary
Secondary
Concomitant
Nausea Life Threatening 7/18/2007 47 Female 11/6/2007 United States
Primary
Secondary
Concomitant
Malaise Life Threatening 7/26/2007 78 Male 11/19/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Syncope Other Serious 11/30/2007 76 Female 154 lb 12/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Malaise Hospitalization 9/8/2007 75 Female 12/17/2007 United Kingdom
Primary
Concomitant
International Normalised Ratio Decreased Other Serious 11/1/2007 Female 295 lb 1/29/2008 Physician United States
Primary
Concomitant
Interacting
Mental Status Changes Hospitalization 7/28/2007 56 Female 1/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Osteoarthritis Other Serious 12/1/2007 Female 2/6/2008 Physician United States
Primary
Concomitant
Pharmaceutical Product Complaint Hospitalization 56 Female 2/7/2008 Other Health Professional United States
Primary
Concomitant
Interacting
Mental Status Changes Hospitalization 2/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 56 Female 2/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Vasovagal Hospitalization 9/8/2007 75 Female 3/7/2008 United Kingdom
Primary
Concomitant
Renal Mass Hospitalization 2/15/2008 Male 228 lb 3/18/2008 United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 56 Female 4/7/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Parkinson's Disease Other Serious Male 230 lb 4/21/2008 Consumer United States
Primary
Concomitant
Amyotrophic Lateral Sclerosis Other Serious 3/1/2007 68 Male 4/24/2008 Other Health Professional Sweden
Primary
Concomitant
Nausea Hospitalization 86 Male 4/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 3/16/2002 45 Male 302 lb 4/29/2008 Consumer United States
Primary
Concomitant
Urinary Retention Other Serious 2/1/2008 Female 137 lb 4/30/2008 Consumer United States
Primary
Concomitant
Acute Myocardial Infarction Life Threatening 1/30/2007 88 Female 141 lb 5/12/2008 Physician United Kingdom
Primary
Concomitant
Coronary Artery Occlusion Hospitalization 4/1/2008 73 Female 5/15/2008 Consumer United States
Primary
Secondary
Concomitant
Nausea Other Serious 5/30/2008 Other Health Professional United States
Primary
Secondary
Blood Glucose Increased Other Serious 5/15/2008 Female 140 lb 5/30/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious Female 3/27/2008 Consumer United States
Primary
Concomitant
Nausea Hospitalization 86 Male 6/2/2008 Physician United States
Primary
Concomitant
Nausea Hospitalization 86 Male 6/2/2008 Physician United States
Primary
Concomitant
Nausea Hospitalization 86 Male 6/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Hospitalization 86 Male 6/11/2008 Other Health Professional United States
Primary
Secondary
Nausea Hospitalization 86 Male 6/12/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Hospitalization 86 Male 6/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Stent Placement Hospitalization 79 Male 6/25/2008 Consumer United States
Primary
Concomitant
Nausea Hospitalization 86 Male 6/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 8/30/2005 Male 139 lb 6/27/2008 United States
Primary
Concomitant
Acute Coronary Syndrome Hospitalization 4/22/2008 Male 6/27/2008 Netherlands
Primary
Concomitant
Death Other Serious 80 Female 163 lb 6/30/2008 Other Health Professional United Kingdom
Primary
Concomitant
Nausea Hospitalization 86 Male 7/21/2008 United States
Primary
Secondary
Concomitant
Nausea Hospitalization 86 Male 7/23/2008 Other Health Professional United States
Primary
Secondary
Cerebrovascular Accident Hospitalization 5/25/2007 80 Male 7/29/2008 Physician United States
Primary
Concomitant
International Normalised Ratio Fluctuation 81 Female 172 lb 7/29/2008 Consumer United States
Primary
Secondary
Concomitant
Multiple Myeloma Other Serious Male 304 lb 8/4/2008 Consumer United Kingdom
Primary
Concomitant
Red Blood Cell Sedimentation Rate Increased Other Serious 6/1/2008 75 Male 161 lb 8/8/2008 Other Health Professional United Kingdom
Primary
Concomitant
No Adverse Event 2/15/2008 Male 228 lb 8/11/2008 United States
Primary
Concomitant
Renal Failure Other Serious 1/1/1998 Male 8/15/2008 United States
Primary
Secondary
Concomitant
Myocardial Ischaemia Death 1/11/2008 Female 163 lb 8/15/2008 United Kingdom
Primary
Concomitant
Somnolence Hospitalization 6/1/2008 Female 8/15/2008 Other Health Professional France
Primary
Concomitant
Weight Decreased 12/1/2007 62 Female 132 lb 7/7/2008 Consumer United States
Primary
Concomitant
Blood Pressure Decreased Other Serious 7/30/2008 68 Male 190 lb 8/25/2008 Other Health Professional United Kingdom
Primary
Concomitant
Flushing 4/19/2008 Male 200 lb 8/27/2008 Consumer United States
Primary
Concomitant
Rash Macular 7/11/2008 Female 8/29/2008 United States
Primary
Concomitant
Upper Limb Fracture Hospitalization 5/26/2008 Female 99 lb 9/3/2008 United Kingdom
Primary
Concomitant
Multiple Myeloma Other Serious Male 304 lb 9/5/2008 Consumer United Kingdom
Primary
Concomitant
Blood Pressure Decreased Other Serious 7/30/2008 68 Male 190 lb 9/8/2008 Other Health Professional United Kingdom
Primary
Concomitant
Blood Pressure Decreased Other Serious 7/30/2008 68 Male 190 lb 9/8/2008 Other Health Professional United Kingdom
Primary
Concomitant
Chest Pain Hospitalization 1/1/2008 Female 9/8/2008 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 9/17/2008 Lawyer United States
Primary
Concomitant
Nausea Hospitalization 86 Male 6/2/2008 Physician United States
Primary
Concomitant
Sciatica Other Serious 8/7/2007 74 Female 198 lb 10/10/2008 Physician Australia
Primary
Concomitant
Myocardial Infarction Other Serious 3/16/2002 45 Male 302 lb 10/14/2008 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2005 61 Male 10/16/2008 Other Health Professional United Kingdom
Primary
Concomitant
Lethargy Other Serious 4/18/2005 Male 10/17/2008 Physician United States
Primary
Concomitant
Neoplasm Malignant Other Serious 1/1/2008 10/24/2008 Physician United States
Primary
Concomitant
Lethargy Other Serious 4/18/2005 Male 10/24/2008 Consumer United States
Primary
Concomitant
Rash Erythematous Female 11/26/2008 United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 1/1/2001 53 Female 211 lb 12/2/2008 Consumer United States
Primary
Concomitant
Renal Impairment Life Threatening 86 Male 12/2/2008 Physician United States
Primary
Secondary
Concomitant

Drug Data