Isosorbide Mononitrate combined with Nicorandil

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Skin Ulcer Hospitalization 2/13/2002 Female 1/4/2006 France
Primary
Concomitant
Exercise Test Abnormal Hospitalization 6/7/2005 68 Male 1/5/2006 Physician United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2000 83 Female 99 lb 1/25/2006 United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 6/6/2002 89 Female 141 lb 1/26/2006 United Kingdom
Primary
Concomitant
Nitritoid Crisis Other Serious 8/22/2002 63 Male 2/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Syncope Vasovagal Other Serious 8/22/2002 63 Male 2/8/2006 Other Health Professional
Primary
Concomitant
Gastric Cancer Other Serious 74 Female 2/15/2006 Consumer Japan
Primary
Secondary
Concomitant
Syncope Vasovagal Other Serious 8/22/2002 63 Male 2/24/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 3/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Vasovagal Other Serious 8/22/2002 63 Male 3/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Haemoptysis Other Serious 2/26/2006 72 Male 224 lb 3/28/2006 Consumer United Kingdom
Primary
Concomitant
Skin Exfoliation Other Serious 3/2/2006 61 Male 4/11/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 4/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vertigo Hospitalization 2/1/2006 92 Male 4/11/2006 Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 5/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Fall Other Serious 2/1/2006 92 Male 4/26/2006 Physician Japan
Primary
Secondary
Concomitant
Anosmia Other Serious 1/29/2006 50 Male 35 lb 5/17/2006 Consumer United Kingdom
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 5/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Fall Other Serious 2/1/2006 92 Male 5/23/2006 Japan
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 4/17/2006 71 Female 141 lb 6/1/2006 Physician United Kingdom
Primary
Concomitant
Tardive Dyskinesia Other Serious 2/1/2006 53 Male 154 lb 6/2/2006 Consumer United Kingdom
Primary
Concomitant
Vertigo Hospitalization 73 Male 6/7/2006 Other Health Professional France
Primary
Secondary
Sinus Headache Disability 5/4/2006 79 Male 212 lb 6/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Gastric Cancer Other Serious 74 Female 6/29/2006 Consumer Japan
Primary
Secondary
Concomitant
Hypovolaemia Hospitalization 5/17/2006 Female 6/30/2006 United Kingdom
Primary
Secondary
Concomitant
Tardive Dyskinesia Other Serious 2/1/2006 53 Male 154 lb 7/17/2006 Other Health Professional Japan
Primary
Concomitant
Pneumonia Death 2/21/2006 79 Male 7/24/2006 Physician Japan
Primary
Concomitant
Tardive Dyskinesia Other Serious 2/1/2006 53 Male 154 lb 7/26/2006 Other Health Professional Japan
Primary
Concomitant
Multi-organ Failure Other Serious 7/2/2006 77 Female 99 lb 7/21/2006 Physician United Kingdom
Primary
Concomitant
Blood Urea Increased Hospitalization 66 Female 176 lb 8/10/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Fall Hospitalization Male 8/21/2006 Pharmacist United Kingdom
Primary
Concomitant
Hypovolaemia Hospitalization 5/17/2006 85 Female 8/11/2006 United Kingdom
Primary
Secondary
Concomitant
Hypovolaemia Other Serious 5/17/2006 Female 8/18/2006 Other Health Professional Denmark
Primary
Concomitant
Vomiting Life Threatening 8/10/2006 60 Male 284 lb 9/1/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 8/10/2006 60 Male 271 lb 9/6/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 82 Female 9/7/2006 Denmark
Primary
Concomitant
Steatorrhoea Life Threatening Male 230 lb 9/25/2006 Physician United Kingdom
Primary
Concomitant
Myalgia Other Serious 5/9/2006 79 Male 182 lb 9/19/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 8/11/2006 64 Male 11/2/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 3/4/2004 62 Male 10/6/2006 United States
Primary
Secondary
Concomitant
Urinary Hesitation Other Serious 10/30/2006 57 Male 1/15/2007 Consumer United Kingdom
Primary
Concomitant
Asthma Other Serious 1/21/2007 42 Male 1/31/2007 Consumer United Kingdom
Primary
Concomitant
Sclerosing Encapsulating Peritonitis 10/1/2006 58 Male 165 lb 1/31/2007 Japan
Primary
Secondary
Concomitant
Asthma Other Serious 1/21/2007 42 Male 2/2/2007 Consumer United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 11/13/2006 89 Male 121 lb 2/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 63 Female 3/1/2007 Physician
Primary
Secondary
Concomitant
Vomiting Hospitalization 63 Female 3/6/2007 Physician
Primary
Secondary
Concomitant
Vomiting Hospitalization 63 Female 3/5/2007 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 63 Female 3/20/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Helicobacter Pylori Identification Test Positive Hospitalization 1/1/2007 63 Female 3/13/2007 United Kingdom
Primary
Secondary
Concomitant
Helicobacter Pylori Identification Test Positive Hospitalization 63 Female 3/15/2007 United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 9/1/2006 46 Male 344 lb 3/27/2007 Physician United Kingdom
Primary
Concomitant
Mouth Ulceration Disability 2/1/2007 4/4/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Myositis Disability 12/1/2006 81 Female 4/6/2007 Consumer United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 1/21/2007 42 Male 4/9/2007 Physician United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Death 11/17/2006 Female 106 lb 4/12/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Death 1/1/2007 77 Female 4/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Retinopathy Other Serious 3/1/2006 Female 4/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sclerosing Encapsulating Peritonitis Hospitalization 8/4/2005 56 Male 165 lb 4/18/2007 Japan
Primary
Secondary
Concomitant
Sclerosing Encapsulating Peritonitis Hospitalization 8/4/2005 56 Male 165 lb 4/18/2007 Japan
Primary
Secondary
Concomitant
Blood Urea Increased Hospitalization 66 Female 176 lb 4/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypotension Other Serious 68 Male 187 lb 5/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Hypotension Other Serious 68 Male 187 lb 5/3/2007 Physician United Kingdom
Primary
Concomitant
Interacting
Angina Pectoris Hospitalization 4/28/2007 62 Female 174 lb 5/11/2007 Consumer United Kingdom
Primary
Concomitant
Retinopathy Other Serious 3/1/2006 Female 5/14/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Diabetic Retinopathy Other Serious 3/1/2006 Female 5/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Wheezing Other Serious 1/1/2007 Male 254 lb 5/17/2007 Physician United Kingdom
Primary
Concomitant
Rash Hospitalization 4/28/2007 77 Male 5/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Angina Pectoris Hospitalization 4/28/2007 62 Female 174 lb 6/4/2007 Consumer United Kingdom
Primary
Concomitant
Rash Hospitalization 4/28/2007 77 Male 183 lb 6/5/2007 Other Health Professional United Kingdom
Primary
Concomitant
Angina Pectoris Hospitalization 4/28/2007 62 Female 174 lb 6/22/2007 Consumer United Kingdom
Primary
Concomitant
Paraesthesia Oral Other Serious 6/15/2007 57 Female 250 lb 7/6/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sinus Tachycardia Life Threatening 63 Male 6/29/2007 Japan
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/21/2007 42 Male 7/27/2007 Physician United Kingdom
Primary
Concomitant
Somnolence Life Threatening 4/18/2007 56 Male 8/1/2007 United Kingdom
Primary
Secondary
Concomitant
Somnolence Life Threatening 4/18/2007 56 Male 8/1/2007 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/11/2007 89 Female 9/14/2007 Other Health Professional France
Primary
Concomitant
Head Injury Hospitalization 6/17/2007 Female 120 lb 10/22/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Sleep Disorder Hospitalization 6/1/2005 62 Male 10/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sleep Disorder Hospitalization 6/1/2005 62 Male 10/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Head Injury Hospitalization 6/17/2007 Female 120 lb 11/13/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Sleep Disorder Hospitalization 6/1/2005 62 Male 11/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Skin Exfoliation Other Serious 10/20/2007 55 Male 181 lb 11/28/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sclerosing Encapsulating Peritonitis Hospitalization 8/1/2005 Male 165 lb 11/29/2007 Japan
Primary
Secondary
Concomitant
Wheezing Other Serious 1/1/2007 Male 254 lb 12/17/2007 Physician United Kingdom
Primary
Concomitant
Tibia Fracture Other Serious 9/7/2007 50 Male 249 lb 12/26/2007 Physician United Kingdom
Primary
Concomitant
Tibia Fracture Other Serious 9/7/2007 50 Male 249 lb 12/27/2007 Physician United Kingdom
Primary
Concomitant
Speech Disorder Other Serious 10/31/2007 Male 196 lb 12/28/2007 Physician United Kingdom
Primary
Concomitant
Ankle Fracture Other Serious 9/8/2007 1/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2005 1/23/2008 Other Health Professional United Kingdom
Primary
Concomitant
Kidney Infection Hospitalization 1/1/2007 Male 1/25/2008 Other Health Professional Australia
Primary
Concomitant
Syncope Vasovagal Disability 5/10/2001 63 Male 12/17/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 10/30/2007 Male 2/14/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Epistaxis Life Threatening 1/1/2007 76 Male 186 lb 2/20/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tibia Fracture Hospitalization 9/8/2007 50 Male 249 lb 2/11/2008 United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2005 3/24/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 3/28/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Rhabdomyolysis Life Threatening 77 Female 3/31/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 4/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 4/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 77 Female 4/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Death 4/10/2008 69 Female 207 lb 4/28/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pancreatitis Hospitalization 4/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 82 Female 5/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Disease Progression Death 69 Female 208 lb 5/2/2008 Consumer United Kingdom
Primary
Concomitant
Pancreatitis Hospitalization 82 Female 5/2/2008 United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Other Serious 82 Female 5/6/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/10/2008 75 Male 6/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 75 Male 6/16/2008 United Kingdom
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 4/7/2008 Female 207 lb 6/27/2008 Consumer United Kingdom
Primary
Concomitant
Death Other Serious 80 Female 163 lb 6/30/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pyoderma Gangrenosum Hospitalization 1/10/2008 Female 163 lb 7/3/2008 United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 9/26/2007 Female 163 lb 7/8/2008 Physician United Kingdom
Primary
Concomitant
Multiple Myeloma Other Serious Male 304 lb 8/4/2008 Consumer United Kingdom
Primary
Concomitant
Myocardial Ischaemia Death 1/11/2008 Female 163 lb 8/15/2008 United Kingdom
Primary
Concomitant
Multiple Myeloma Other Serious Male 304 lb 9/5/2008 Consumer United Kingdom
Primary
Concomitant
Jaundice Cholestatic Other Serious 8/11/2008 Female 9/15/2008 Other Health Professional Japan
Primary
Concomitant
Sciatica Other Serious 8/7/2007 74 Female 198 lb 10/10/2008 Physician Australia
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2005 61 Male 10/16/2008 Other Health Professional United Kingdom
Primary
Concomitant
Hypovolaemia Other Serious 5/17/2006 Female 10/22/2008 Denmark
Primary
Concomitant
Ventricular Fibrillation Life Threatening 10/14/2008 Male 95 lb 11/18/2008 Physician Japan
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 10/14/2008 Male 95 lb 12/2/2008 Physician Japan
Primary
Secondary
Concomitant
Rash Pruritic Other Serious 11/29/2008 Male 12/18/2008 Physician United Kingdom
Primary
Concomitant
Throat Tightness Other Serious 12/5/2008 59 Female 179 lb 1/8/2009 Physician United Kingdom
Primary
Concomitant
Cerebrovascular Accident Other Serious 80 Female 163 lb 1/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Other Serious 10/1/2008 Male 152 lb 1/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 7/1/2008 85 Female 117 lb 1/21/2009 Physician United Kingdom
Primary
Concomitant
Jaundice Cholestatic Other Serious 8/11/2008 84 Female 2/10/2009 Other Health Professional Japan
Primary
Concomitant
Myocardial Infarction Other Serious Male 152 lb 2/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 2/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Rhabdomyolysis Hospitalization 77 Female 2/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 77 Female 2/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pemphigoid Other Serious 12/12/2008 Female 3/5/2009 Physician United Kingdom
Primary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 3/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 77 Female 3/2/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 3/2/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 3/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 77 Female 3/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 3/11/2009
Primary
Secondary
Concomitant
Anaphylactic Shock Life Threatening 3/11/2009 71 Male 3/19/2009 Physician Japan
Primary
Concomitant
Rhabdomyolysis Other Serious 77 Female 3/20/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 77 Female 3/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 1/1/2009 77 Female 3/20/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 77 Female 3/23/2009 United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 77 Female 4/7/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 77 Female 4/7/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 7/1/2008 85 Female 117 lb 4/8/2009 Physician United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 77 Female 4/14/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 77 Female 4/15/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 77 Female 4/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting

Drug Data