Isosorbide Mononitrate combined with Nexium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rectal Polyp Hospitalization 8/14/2005 64 Female 154 lb 12/30/2005 Physician United States
Primary
Concomitant
Muscle Disorder Hospitalization 12/25/2005 71 Male 1/11/2006 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2005 70 Female 1/10/2006 Pharmacist Netherlands
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 2/1/2004 Female 128 lb 1/24/2006 Physician United States
Primary
Concomitant
Rectal Polyp Hospitalization 8/14/2005 64 Female 154 lb 1/20/2006 Physician United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 2/1/2004 Female 128 lb 2/10/2006 Physician United States
Primary
Concomitant
Nightmare Disability 8/1/2005 69 Male 2/20/2006 Pharmacist United Kingdom
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 2/1/2004 Female 128 lb 3/3/2006 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2005 70 Female 2/27/2006 Pharmacist Netherlands
Primary
Secondary
Concomitant
Ventricular Hypertrophy Hospitalization 6/1/2000 66 Female 157 lb 3/31/2006 Physician United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 3/11/2006 72 Male 4/12/2006 Consumer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 9/29/2003 Male 5/16/2006 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/1/2005 57 Female 7/19/2006 Consumer United States
Primary
Concomitant
Tongue Oedema Other Serious 62 Male 9/28/2006 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2006 62 Male 224 lb 9/29/2006 Physician United States
Primary
Concomitant
Injection Site Pain 5/1/2006 Female 12/20/2006 Pharmacist United States
Primary
Concomitant
Tremor Hospitalization 11/1/2006 70 Male 3/8/2007 Consumer United States
Primary
Concomitant
Renal Disorder Hospitalization 2/16/2007 51 Female 3/12/2007 Consumer United States
Primary
Concomitant
Tremor Hospitalization 11/1/2006 70 Male 4/27/2007 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 1/27/2007 56 Male 110 lb 4/18/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 2/16/2007 51 Female 4/27/2007 Consumer United States
Primary
Concomitant
Small Cell Lung Cancer Stage Unspecified Other Serious 6/15/2007 73 Female 6/28/2007 Pharmacist United States
Primary
Concomitant
Tremor Other Serious 1/1/2006 71 Female 7/20/2007 Consumer United States
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 1/4/2006 82 Female 9/4/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Muscle Spasticity Other Serious 1/1/2007 Female 177 lb 9/10/2007 United States
Primary
Secondary
Concomitant
Rash 5/23/2007 Female 9/26/2007 Consumer United States
Primary
Concomitant
Mental Status Changes Hospitalization 7/28/2007 56 Female 9/28/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Depressed Mood 4/23/2007 Female 12/13/2007 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Decreased Other Serious 11/1/2007 Female 295 lb 1/29/2008 Physician United States
Primary
Concomitant
Interacting
Mental Status Changes Hospitalization 7/28/2007 56 Female 1/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Hospitalization 56 Female 2/7/2008 Other Health Professional United States
Primary
Concomitant
Interacting
Mental Status Changes Hospitalization 2/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 56 Female 2/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 66 Male 4/4/2008 Consumer United States
Primary
Concomitant
Mental Status Changes Hospitalization 56 Female 4/7/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 8/29/2007 Male 5/12/2008 Consumer United States
Primary
Concomitant
Skin Laceration Hospitalization 5/1/2008 76 Male 195 lb 5/20/2008 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 8/1/2007 Male 6/13/2008 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 5/1/2008 76 Male 195 lb 9/3/2008 United States
Primary
Secondary
Concomitant
Syncope Hospitalization 1/1/2008 85 Female 10/7/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 5/1/2008 76 Male 195 lb 10/6/2008 United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 1/1/2001 53 Female 211 lb 12/2/2008 Consumer United States
Primary
Concomitant
Hypertension Other Serious 11/10/2008 44 Male 11/25/2008 Consumer United States
Primary
Concomitant
Speech Disorder Hospitalization 11/19/2008 76 Male 178 lb 12/16/2008 Consumer United States
Primary
Concomitant
Tremor Hospitalization 10/28/2008 75 Female 156 lb 12/22/2008 Consumer United States
Primary
Concomitant
Troponin Increased Other Serious 10/1/2008 Female 154 lb 12/29/2008 Consumer Ireland
Primary
Concomitant
Product Quality Issue Other Serious 1/1/2007 86 Female 12/30/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 10/1/2008 47 Female 134 lb 12/30/2008 Consumer United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 1/1/2001 53 Female 211 lb 1/14/2009 Consumer United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 4/1/2008 56 Female 1/15/2009 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 5/1/2007 72 Male 210 lb 1/21/2009 Consumer United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 53 Female 211 lb 1/28/2009 Other Health Professional United States
Primary
Concomitant
Product Quality Issue Hospitalization 5/1/2008 87 Female 161 lb 1/23/2009 Consumer United States
Primary
Concomitant
Mental Status Changes 56 Female 8/20/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 53 Female 211 lb 2/16/2009 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2004 77 Female 241 lb 2/23/2009 Consumer United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 53 Female 211 lb 3/2/2009 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 2/18/2009 67 Female 187 lb 3/9/2009 Other Health Professional United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 2/18/2009 67 Female 188 lb 3/4/2009 Other Health Professional United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 2/18/2009 67 Female 188 lb 3/4/2009 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 2/18/2009 67 Female 185 lb 3/10/2009 Other Health Professional United States
Primary
Concomitant
Road Traffic Accident Hospitalization 5/10/2008 Female 176 lb 3/25/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 8/7/2008 Male 165 lb 3/26/2009 Other Health Professional United States
Primary
Concomitant
Osteoarthritis Other Serious 11/1/2008 Male 4/8/2009 Physician United States
Primary
Concomitant
Osteoarthritis Other Serious 11/1/2008 Male 196 lb 4/10/2009 Physician United States
Primary
Concomitant
Osteoarthritis Other Serious 11/1/2008 Male 196 lb 4/22/2009 Physician United States
Primary
Concomitant
Osteoarthritis Other Serious 11/1/2008 Male 181 lb 4/28/2009 Physician United States
Primary
Concomitant
Haemoglobin Decreased 3/23/2009 Female 5/4/2009 Consumer United States
Primary
Concomitant
Osteoarthritis Other Serious 11/1/2008 Male 181 lb 5/21/2009 Physician United States
Primary
Concomitant
Myocardial Infarction Death 1/29/2009 77 Male 5/21/2009 Consumer United States
Primary
Concomitant
Neck Pain Hospitalization 6/12/2009 61 6/19/2009 Physician Philippines
Primary
Secondary
Concomitant
Hypertensive Crisis Hospitalization 6/12/2009 61 6/26/2009 Physician Philippines
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/22/2000 45 Male 266 lb 7/10/2009 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 4/1/2008 Male 165 lb 7/17/2009 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Decreased 10/22/2008 82 Female 161 lb 7/22/2009 Consumer United States
Primary
Concomitant
Hyperglycaemic Hyperosmolar Nonketotic Syndrome Other Serious 4/5/2004 60 Female 180 lb 7/22/2009 United States
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 7/1/2008 59 Male 7/23/2009 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased 10/22/2008 82 Female 161 lb 7/22/2009 Consumer United States
Primary
Concomitant
Vertigo Hospitalization 80 Male 8/14/2009 Lawyer United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 1/1/2001 53 Female 211 lb 9/21/2009 Other Health Professional United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 3/10/1998 54 Male 209 lb 9/23/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 9/9/2009 75 Male 199 lb 9/16/2009 Physician United States
Primary
Secondary
Concomitant
Troponin Increased Other Serious 10/1/2008 Female 154 lb 10/12/2009 Consumer Ireland
Primary
Concomitant
Unevaluable Event Hospitalization 11/6/2009 Female 12/10/2009 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 12/24/2006 61 Male 224 lb 1/20/2010 Lawyer United States
Primary
Concomitant
Wheezing Hospitalization 11/27/2006 76 Female 145 lb 1/20/2010 Lawyer United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 1/1/1978 61 Male 224 lb 1/26/2010 Lawyer United States
Primary
Concomitant
Reflux Gastritis Other Serious 9/8/2006 Male 290 lb 2/9/2010 Physician United States
Primary
Concomitant
Vertigo Hospitalization 79 Male 142 lb 1/27/2010 Lawyer United States
Primary
Concomitant
Wound Infection Hospitalization 82 Female 167 lb 2/5/2010 United States
Primary
Concomitant
Wound Infection Hospitalization 82 Female 167 lb 2/5/2010 United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 Male 3/4/2010 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 10/14/2008 77 Female 3/3/2010 Consumer United States
Primary
Concomitant
Wheezing Hospitalization 11/27/2006 76 Female 145 lb 3/3/2010 Lawyer United States
Primary
Concomitant
Wound Infection Hospitalization 82 Female 167 lb 3/9/2010 Lawyer United States
Primary
Concomitant
Constipation 2/1/2009 48 Female 200 lb 5/5/2010 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 79 Male 142 lb 5/26/2010 Lawyer United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 6/3/2010 Other Health Professional United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious Female 176 lb 6/23/2010 Physician United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 53 Female 211 lb 7/7/2010 Other Health Professional United States
Primary
Concomitant
Bronchitis 12/1/2006 60 Female 130 lb 7/9/2010 Consumer United States
Primary
Concomitant
Mental Status Changes Hospitalization 7/28/2007 56 Female 7/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Hospitalization 10/14/2002 41 Female 165 lb 7/26/2010 Lawyer United States
Primary
Secondary
Concomitant
Muscle Spasms 10/6/2009 64 Female 182 lb 8/27/2010 United States
Primary
Concomitant
Flushing 10/22/2009 65 Male 210 lb 8/28/2010 United States
Primary
Concomitant
Oesophageal Stenosis Hospitalization Male 9/9/2010 Physician Netherlands
Primary
Concomitant
Vomiting Other Serious 2/6/2008 51 Male 163 lb 9/21/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Other Serious 6/26/2010 58 Female 176 lb 10/7/2010 Physician United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 10/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/21/2010 85 Male 215 lb 10/27/2010 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 8/21/2010 85 Male 215 lb 10/29/2010 Physician United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 11/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 9/29/2010 11/5/2010 Pharmacist United States
Primary
Concomitant
Squamous Cell Carcinoma Hospitalization 8/21/2010 85 Male 215 lb 11/12/2010 Physician United States
Primary
Concomitant
Constipation 2/1/2009 48 Female 200 lb 11/12/2010 Consumer United States
Primary
Concomitant
Headache Other Serious 4/19/2010 70 Female 154 lb 11/16/2010 Physician Netherlands
Primary
Concomitant
Unresponsive To Stimuli Other Serious 2/21/2008 69 Female 150 lb 12/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Female 194 lb 11/22/2010 United States
Primary
Concomitant
Vomiting Other Serious 6/26/2010 58 Female 176 lb 12/16/2010 Physician United States
Primary
Concomitant
Headache 4/19/2010 70 Female 154 lb 12/20/2010 Physician Netherlands
Primary
Concomitant
Vomiting Other Serious 12/2/2007 50 Female 134 lb 12/7/2010 Lawyer United States
Primary
Concomitant
Sinus Tachycardia Other Serious 2/21/2008 69 Female 150 lb 1/31/2011 Pharmacist United States
Primary
Secondary
Concomitant
Pain Other Serious 12/2/2007 50 Female 134 lb 2/8/2011 Lawyer United States
Primary
Concomitant
Haemorrhage Hospitalization 87 Male 4/7/2011 United States
Primary
Concomitant
Skin Exfoliation Other Serious 4/1/2011 51 Male 210 lb 4/18/2011 Consumer United States
Primary
Concomitant
Arrhythmia Other Serious 12/1/2007 54 Male 163 lb 4/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hypoaesthesia Facial Hospitalization 12/2/2007 50 Female 61 lb 4/18/2011 Lawyer United States
Primary
Concomitant
Fear Other Serious 1/27/2003 64 Male 310 lb 4/29/2011 Other Health Professional United States
Primary
Concomitant
Nausea 4/8/2011 76 Male 220 lb 5/16/2011 Consumer United States
Primary
Concomitant
Pollakiuria Hospitalization 10/14/2008 77 Female 4/29/2011 Consumer United States
Primary
Concomitant
Dystonia Other Serious 7/1/2009 58 Female 175 lb 5/23/2011 Lawyer United States
Primary
Concomitant
Renal Injury Other Serious 2/10/2005 83 Male 194 lb 6/10/2011 Other Health Professional United States
Primary
Concomitant
Abdominal Discomfort Hospitalization 12/1/2010 81 Female 6/13/2011 Consumer United States
Primary
Concomitant
Haematuria Hospitalization 6/11/2011 55 Female 238 lb 6/17/2011 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Death Male 190 lb 6/24/2011 Consumer United States
Primary
Concomitant
Chorea Disability 1/1/2003 61 Female 6/22/2011 Physician United States
Primary
Concomitant
Renal Failure Death Male 190 lb 7/5/2011 Consumer United States
Primary
Concomitant
Neck Pain Other Serious 65 Female 178 lb 7/5/2011 Lawyer United States
Primary
Concomitant
Renal Failure Chronic Other Serious 11/1/2009 64 Male 230 lb 7/13/2011 Physician United States
Primary
Concomitant
Thrombocytopenia Death 12/1/2007 54 Male 163 lb 7/22/2011 Lawyer United States
Primary
Secondary
Concomitant
Cardiac Output Decreased Other Serious 12/1/2007 54 Male 163 lb 7/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Prothrombin Level Decreased 73 Female 7/25/2011 Consumer United States
Primary
Concomitant
Skin Burning Sensation Male 190 lb 8/5/2011 Consumer United States
Primary
Concomitant
Arrhythmia Hospitalization Male 8/10/2011 Pharmacist United States
Primary
Concomitant
Blood Potassium Decreased Other Serious 9/1/2011 90 Male 9/16/2011 Pharmacist United States
Primary
Concomitant
Pain Death 1/27/2003 70 Male 311 lb 9/28/2011 Consumer United States
Primary
Concomitant
Arthritis Hospitalization 5/26/2011 65 Female 231 lb 10/15/2011 United States
Primary
Secondary
Concomitant
Back Pain Other Serious 3/1/2008 54 Male 10/21/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Hypersensitivity Other Serious 12/7/2009 48 Male 11/10/2011 Other Health Professional United States
Primary
Concomitant

Drug Data