Isosorbide Mononitrate combined with Metoprolol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Exercise Test Abnormal Hospitalization 6/7/2005 68 Male 1/5/2006 Physician United Kingdom
Primary
Concomitant
Hepatitis Hospitalization 2/9/2005 69 Male 4/4/2005 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 1/1/2003 76 Female 201 lb 1/19/2006 Lawyer United States
Primary
Concomitant
Vitamin B12 Deficiency Hospitalization 1/1/2003 76 Female 201 lb 1/23/2006 Physician United States
Primary
Concomitant
Coronary Artery Thrombosis Other Serious 8/10/2004 50 Male 1/25/2006 Physician Brazil
Primary
Concomitant
Rash 5/1/2005 64 Female 324 lb 1/30/2006 Consumer United States
Primary
Secondary
Concomitant
Dizziness Postural Hospitalization 10/12/2005 Male 144 lb 10/13/2005 Pharmacist United States
Primary
Secondary
Concomitant
Subcutaneous Haematoma Hospitalization 6/15/2005 66 Male 198 lb 2/9/2006 Poland
Primary
Concomitant
Interacting
Pain In Extremity Other Serious 10/14/2005 75 Male 210 lb 1/17/2006 Other Health Professional United States
Primary
Concomitant
Dizziness Other Serious 11/14/2005 75 Male 215 lb 2/7/2006 Other Health Professional United States
Primary
Concomitant
Nasopharyngitis Hospitalization 7/9/1999 77 Female 2/23/2006 Physician United States
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 3/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 10/1/2004 94 Female 103 lb 12/27/2005 Consumer United States
Primary
Concomitant
Intestinal Functional Disorder Hospitalization 7/18/2003 79 Female 3/28/2006 Lawyer United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 1/1/2001 64 Male 198 lb 3/30/2006 Physician United States
Primary
Concomitant
Intestinal Functional Disorder Hospitalization 7/18/2003 79 Female 4/3/2006 Lawyer United States
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 4/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Coronary Artery Disease Hospitalization 1/22/2005 76 Male 185 lb 4/6/2006 Czech Republic
Primary
Secondary
Concomitant
Road Traffic Accident Hospitalization 6/23/2002 72 Male 192 lb 4/20/2006 Lawyer United States
Primary
Concomitant
Vitamin B12 Deficiency Hospitalization 1/1/2003 76 Female 201 lb 4/20/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2003 67 Female 121 lb 4/25/2006 Lawyer United States
Primary
Concomitant
Road Traffic Accident Hospitalization 6/23/2002 72 Male 192 lb 4/26/2006 Physician United States
Primary
Concomitant
Vitamin B12 Deficiency Hospitalization 1/1/2003 76 Female 201 lb 4/27/2006 Physician United States
Primary
Concomitant
Syncope Other Serious 4/1/2006 67 Female 5/11/2006 Consumer United States
Primary
Concomitant
Urinary Tract Infection Enterococcal Life Threatening 12/22/2005 87 Male 5/10/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Enterococcal Life Threatening 12/22/2005 87 Male 5/19/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 7/17/2006 Female 8/1/2006 Physician Australia
Primary
Concomitant
Vitreous Haemorrhage Required Intervention 2/9/2003 84 Male 8/8/2006 Denmark
Primary
Concomitant
Myocardial Infarction Death 8/10/2006 77 Male 9/22/2006 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Back Pain 2/6/2006 63 Male 251 lb 9/27/2006 Other Health Professional United States
Primary
Concomitant
Presyncope Hospitalization 9/8/2006 Male 209 lb 11/4/2006 Pharmacist United States
Primary
Concomitant
Rash Hospitalization 4/28/2007 77 Male 5/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rash Hospitalization 4/28/2007 77 Male 183 lb 6/5/2007 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Other Serious 6/27/2003 Female 228 lb 9/26/2007 Lawyer United States
Primary
Secondary
Concomitant
Hypothyroidism 83 Female 10/1/2007 United States
Primary
Concomitant
Tachycardia Other Serious 9/21/2007 Female 10/31/2007 Physician China
Primary
Concomitant
Vertigo Hospitalization 10/25/2007 65 Female 167 lb 11/29/2007 Physician Hungary
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 11/2/2007 Female 12/5/2007 Australia
Primary
Secondary
Concomitant
Hypotension Hospitalization 12/6/2007 66 Female 151 lb 12/18/2007 Physician Hungary
Primary
Secondary
Concomitant
Hip Fracture Hospitalization 1/1/2007 Male 12/26/2007 Consumer Australia
Primary
Concomitant
Pruritus Other Serious 52 Male 12/21/2007 Consumer United Kingdom
Primary
Secondary
Abdominal Wall Abscess Hospitalization 3/29/2007 Female 134 lb 12/28/2007 United Kingdom
Primary
Concomitant
Ankle Fracture Other Serious 9/8/2007 1/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Dyspepsia Other Serious 1/1/2006 77 Female 154 lb 4/8/2008 Consumer Australia
Primary
Secondary
Concomitant
Nausea Hospitalization 86 Male 4/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Hospitalization 86 Male 6/2/2008 Physician United States
Primary
Concomitant
Nausea Hospitalization 86 Male 6/2/2008 Physician United States
Primary
Concomitant
Nausea Hospitalization 86 Male 6/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Hospitalization 86 Male 6/11/2008 Other Health Professional United States
Primary
Secondary
Nausea Hospitalization 86 Male 6/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Stent Placement Hospitalization 79 Male 6/25/2008 Consumer United States
Primary
Concomitant
Acute Coronary Syndrome Hospitalization 4/22/2008 Male 6/27/2008 Netherlands
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 7/8/2008 Female 191 lb 9/4/2008 Other Health Professional United States
Primary
Concomitant
Viral Infection Hospitalization 9/10/2008 Female 226 lb 9/29/2008 Physician Hungary
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 1/1/2001 53 Female 211 lb 12/2/2008 Consumer United States
Primary
Concomitant
Dyspepsia 2/1/2008 69 Female 265 lb 1/5/2009 Consumer United States
Primary
Secondary
Concomitant
Troponin Increased Other Serious 1/1/2003 78 Male 140 lb 1/8/2009 United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 1/1/2001 53 Female 211 lb 1/14/2009 Consumer United States
Primary
Concomitant
Respiratory Distress Congenital Anomaly 12/30/2007 Female 9 lb 1/30/2009 Pharmacist United States
Primary
Secondary
Concomitant
Product Quality Issue Other Serious 1/1/2005 55 Male 170 lb 2/12/2009 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 10/1/2006 79 Male 160 lb 2/6/2009 Consumer United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 53 Female 211 lb 3/2/2009 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 6/1/2003 73 Female 3/16/2009 United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 6/1/2003 73 Female 3/20/2009 United States
Primary
Secondary
Concomitant
Respiratory Distress Congenital Anomaly 12/30/2007 Female 9 lb 3/27/2009 Pharmacist United States
Primary
Secondary
Concomitant
Anaemia Hospitalization 10/25/2007 Female 167 lb 3/30/2009 Physician Hungary
Primary
Secondary
Concomitant
Anaemia Hospitalization 12/6/2007 Female 151 lb 3/30/2009 Physician Hungary
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 8/29/2007 80 Male 5/8/2009 Other Health Professional China
Primary
Concomitant
Respiratory Failure Hospitalization 3/1/2007 66 Female 246 lb 5/8/2009 Consumer United States
Primary
Concomitant
Ventricular Fibrillation Other Serious 8/29/2007 80 Male 5/18/2009 Other Health Professional China
Primary
Concomitant
Flushing 4/25/2009 Male 214 lb 5/27/2009 United States
Primary
Concomitant
Neck Pain Hospitalization 6/12/2009 61 6/19/2009 Physician Philippines
Primary
Secondary
Concomitant
Hypertensive Crisis Hospitalization 6/12/2009 61 6/26/2009 Physician Philippines
Primary
Secondary
Concomitant
Social Problem Death 82 Female 7/22/2009 Lawyer United States
Primary
Concomitant
Myocardial Ischaemia Hospitalization 9/1/2005 70 Female 204 lb 8/11/2009 Physician United States
Primary
Concomitant
Suicide Attempt Hospitalization 7/13/2009 82 Female 8/11/2009 Germany
Primary
Secondary
Pruritus 10/15/2008 Male 8/22/2009 United States
Primary
Concomitant
Tinnitus Death 80 Female 8/21/2009 Lawyer United States
Primary
Concomitant
Renal Impairment Other Serious 6/23/2009 70 Male 165 lb 9/10/2009 Physician United States
Primary
Secondary
Concomitant
Interacting
Head Injury Life Threatening 6/23/2009 Female 179 lb 6/23/2009 Pharmacist United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 9/8/2009 66 Female 229 lb 10/1/2009 Pharmacist United States
Primary
Secondary
Concomitant
Vitamin D Deficiency Hospitalization 72 Female 9/23/2009 United States
Primary
Concomitant
Acute Coronary Syndrome Hospitalization 4/22/2008 55 10/8/2009 Physician Netherlands
Primary
Concomitant
Respiratory Failure Hospitalization 9/6/2009 57 Female 283 lb 10/7/2009 Other Health Professional United States
Primary
Concomitant
Nausea Other Serious 86 Male 10/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pain In Extremity 7/20/2009 Male 10/16/2009 Other Health Professional United States
Primary
Concomitant
Visual Impairment Other Serious 82 Female 10/18/2009 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 1/1/2001 Female 110 lb 10/20/2009 Consumer United States
Primary
Concomitant
Nausea Hospitalization 86 Male 10/17/2009 Other Health Professional United States
Primary
Secondary
Vomiting Other Serious 82 Female 10/26/2009 United States
Primary
Concomitant
Pneumonia Other Serious 10/15/2009 Female 117 lb 11/9/2009 Sweden
Primary
Concomitant
Stress Ulcer Hospitalization 7/14/2009 53 Male 11/10/2009 China
Primary
Secondary
Concomitant
Stress Ulcer Hospitalization 7/14/2009 53 Male 11/10/2009 China
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 64 Male 11/18/2009 United States
Primary
Concomitant
Vomiting Other Serious 82 Female 11/16/2009 United States
Primary
Concomitant
Myocardial Ischaemia Hospitalization 9/1/2005 70 Female 204 lb 12/1/2009 Consumer United States
Primary
Concomitant
Myalgia Death 1/1/2009 Male 11/25/2009 Consumer United States
Primary
Concomitant
Stress Ulcer Hospitalization 7/14/2008 53 Male 12/17/2009 China
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 7/14/2008 53 Male 12/17/2009 China
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 7/14/2008 53 Male 1/4/2010 China
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 7/13/2008 53 Male 1/7/2010 China
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 64 Male 1/8/2010 United States
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 1/25/2010 Consumer United States
Primary
Concomitant
Paraesthesia Oral Hospitalization 57 Male 1/26/2010 Norway
Primary
Concomitant
Vascular Graft Other Serious 1/1/1996 Male 206 lb 1/29/2010 Consumer United States
Primary
Secondary
Concomitant
Wound Infection Hospitalization 82 Female 167 lb 2/5/2010 United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/20/2010 Male 206 lb 3/23/2010 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2009 Female 170 lb 3/31/2010 Consumer United States
Primary
Concomitant
Vascular Graft Other Serious 1/1/1996 69 Male 206 lb 4/13/2010 Consumer United States
Primary
Secondary
Concomitant
Death Death 4/15/2010 73 Male 4/26/2010 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 3/1/2009 72 Male 189 lb 4/27/2010 Consumer United States
Primary
Concomitant
Malaise Other Serious 1/8/2010 65 Male 4/23/2010 Physician Sweden
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 12/1/2007 79 Male 205 lb 4/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 4/15/2010 73 Male 5/4/2010 Physician United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2009 83 Female 170 lb 5/6/2010 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/9/2010 70 Female 5/21/2010 Physician Netherlands
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 12/1/2007 79 Male 205 lb 5/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis In Device Hospitalization 11/1/2009 72 Female 5/27/2010 Consumer Russian Federation
Primary
Concomitant
Sinus Bradycardia Life Threatening 4/13/2010 63 Male 154 lb 6/17/2010 Other Health Professional United Kingdom
Primary
Concomitant
Transplant Rejection Other Serious 9/23/2008 53 Male 247 lb 6/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 53 Female 211 lb 7/7/2010 Other Health Professional United States
Primary
Concomitant
Drug Effect Decreased Life Threatening 6/11/2010 78 Female 168 lb 7/2/2010 Other Health Professional United States
Primary
Concomitant
Nightmare 3/19/2007 70 Female 149 lb 7/12/2010 Consumer United States
Primary
Concomitant
Heart Rate Increased 10/19/2007 45 Male 216 lb 7/16/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 6/15/2010 56 Male 220 lb 7/15/2010 Physician United States
Primary
Secondary
Concomitant
Acute Coronary Syndrome Hospitalization 4/22/2008 55 Male 8/4/2010 Physician Netherlands
Primary
Concomitant
Haemoglobin Decreased Other Serious Male 8/26/2010 Consumer United States
Primary
Concomitant
Flushing 4/1/2008 67 Female 158 lb 8/28/2010 United States
Primary
Concomitant
Flushing 10/22/2009 65 Male 210 lb 8/28/2010 United States
Primary
Concomitant
Hypertension Other Serious 8/21/2010 90 Male 192 lb 8/30/2010 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2009 83 Female 170 lb 9/16/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 2/6/2008 51 Male 163 lb 9/21/2010 Other Health Professional United States
Primary
Concomitant
Stent Placement Hospitalization 8/1/2009 83 Male 9/21/2010 Consumer United States
Primary
Concomitant
Sinus Bradycardia Life Threatening 4/13/2010 63 Male 154 lb 9/30/2010 Other Health Professional United Kingdom
Primary
Concomitant
Death Death 9/1/2010 78 Male 194 lb 10/20/2010 Physician Australia
Primary
Secondary
Concomitant
Eyelid Oedema Other Serious 78 Female 10/25/2010 Pharmacist Canada
Primary
Concomitant
Death Death 10/25/2010 Physician United States
Primary
Concomitant
Pneumonia Life Threatening 9/1/2010 78 Male 194 lb 10/27/2010 Physician Australia
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 2/10/2004 60 Female 141 lb 11/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Life Threatening 9/1/2010 78 Male 194 lb 11/3/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 9/29/2010 11/5/2010 Pharmacist United States
Primary
Concomitant
Pain In Extremity 9/10/2010 57 Female 220 lb 11/9/2010 Consumer United States
Primary
Concomitant
Pneumonia Life Threatening 9/28/2010 78 Male 194 lb 11/10/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 10/1/2009 70 Female 11/18/2010 Physician United States
Primary
Secondary
Concomitant
Thrombophlebitis Superficial Hospitalization 63 Male 146 lb 11/13/2010 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 9/1/2010 78 Female 236 lb 11/23/2010 Pharmacist Canada
Primary
Concomitant
Thrombosis Hospitalization 63 146 lb 11/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Fall Other Serious 12/3/2010 59 Male 289 lb 12/9/2010 Consumer United States
Primary
Concomitant
Renal Failure Female 194 lb 11/22/2010 United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2009 83 Female 170 lb 5/6/2010 Consumer United States
Primary
Concomitant

Drug Data