Isosorbide Mononitrate combined with Metoprolol Tartrate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hyponatraemia Hospitalization 7/13/2001 Female 1/4/2006 Finland
Primary
Concomitant
Stent Occlusion Hospitalization 7/25/2005 64 Male 183 lb 1/12/2006 Poland
Primary
Secondary
Concomitant
Dizziness Postural Hospitalization 10/19/2005 Male 207 lb 12/2/2005 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/6/2006 59 Male 128 lb 2/23/2006 Physician Germany
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 8/1/2003 Male 3/3/2006 Consumer Australia
Primary
Secondary
Concomitant
Traumatic Intracranial Haemorrhage Death 10/1/2005 95 Male 12/27/2005 United States
Primary
Concomitant
Swelling Face Other Serious 3/20/2005 72 Male 278 lb 12/21/2005 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 2/6/2006 59 Male 128 lb 3/30/2006 Physician Germany
Primary
Secondary
Concomitant
Sepsis Hospitalization 2/6/2006 59 Male 128 lb 4/5/2006 Physician Germany
Primary
Secondary
Concomitant
Myalgia Other Serious 7/22/2005 51 Male 227 lb 4/13/2006 Pharmacist United States
Primary
Concomitant
Vitreous Haemorrhage Other Serious 2/9/2003 84 Male 4/20/2006 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/6/2006 59 Male 128 lb 4/18/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Surgery Hospitalization 2/1/2003 55 Male 4/27/2006 Physician Norway
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 7/16/2004 81 Female 4/28/2006 Norway
Primary
Concomitant
Myocardial Infarction Hospitalization 8/20/2003 72 Female 5/1/2006 Norway
Primary
Concomitant
Treatment Noncompliance Hospitalization 2/26/2006 Male 258 lb 5/2/2006 Pharmacist United States
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 2/27/2006 Male 258 lb 5/2/2006 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 7/30/2005 66 Male 203 lb 5/3/2006 Other Health Professional Hungary
Primary
Secondary
Concomitant
Syncope Required Intervention 12/1/2005 77 Female 12/2/2005 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 12/22/2005 87 Male 5/1/2006 Physician United Kingdom
Primary
Concomitant
Dizziness Hospitalization 2/23/2006 89 Male 5/9/2006 Other Health Professional Ireland
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 8/1/2005 70 Female 122 lb 1/13/2006 Physician United States
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 5/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Large Intestinal Ulcer Other Serious 4/5/2006 50 Male 218 lb 4/7/2006 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Life Threatening 12/22/2005 87 Male 5/26/2006 United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Enterococcal Life Threatening 12/22/2005 87 Male 6/7/2006 United Kingdom
Primary
Secondary
Concomitant
Hallucination Hospitalization 11/1/2001 74 Male 6/23/2006 Other Health Professional Sweden
Primary
Concomitant
Epilepsy Hospitalization 5/19/2006 58 Female 6/28/2006 Physician Austria
Primary
Concomitant
Weight Increased Hospitalization 4/13/2006 67 Male 6/29/2006 Physician United States
Primary
Secondary
Concomitant
Tongue Biting Hospitalization 5/19/2006 58 Female 6/28/2006 Physician Austria
Primary
Concomitant
Heart Rate Irregular Hospitalization 5/21/2006 64 Male 224 lb 5/23/2006 Pharmacist United States
Primary
Concomitant
Tongue Biting Hospitalization 5/19/2006 58 Female 7/27/2006 Physician Australia
Primary
Concomitant
Aplasia Pure Red Cell Other Serious 7/17/2006 Female 8/9/2006 Physician Australia
Primary
Concomitant
Coronary Artery Disease Hospitalization 6/19/2001 72 Male 159 lb 8/15/2006 France
Primary
Concomitant
Syncope Hospitalization 7/26/2006 64 Male 205 lb 8/17/2006 Consumer United States
Primary
Secondary
Concomitant
Eyelid Function Disorder Other Serious 82 Female 145 lb 8/15/2006 Physician United States
Primary
Concomitant
Syncope Hospitalization 7/26/2006 64 Male 205 lb 9/6/2006 Consumer United States
Primary
Secondary
Concomitant
Haemoglobin Increased Other Serious 7/17/2006 Female 9/7/2006 Physician Australia
Primary
Concomitant
Rash Required Intervention 5/13/2006 47 Female 242 lb 5/23/2006 Pharmacist United States
Primary
Concomitant
Ill-defined Disorder Hospitalization 7/7/2006 82 Male 192 lb 10/4/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Hospitalization 78 Male 99 lb 10/10/2006 Consumer United States
Primary
Concomitant
Myocardial Infarction Death 8/10/2006 77 Male 10/18/2006 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Vascular Dementia Hospitalization 7/6/2006 74 Male 170 lb 10/17/2006 Physician Netherlands
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 9/27/2006 Male 10/23/2006 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 3/1/2006 Female 162 lb 10/27/2006 Physician United States
Primary
Concomitant
Hypotension Hospitalization 9/9/2006 64 Male 265 lb 9/29/2006 Pharmacist United States
Primary
Secondary
Renal Failure Acute Other Serious 74 Female 150 lb 11/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Haematoma Other Serious 68 Male 164 lb 11/10/2006 Other Health Professional New Zealand
Primary
Concomitant
Renal Failure Acute Other Serious 74 Female 150 lb 11/9/2006 United Kingdom
Primary
Concomitant
Completed Suicide Death 82 12/18/2006 United States
Primary
Secondary
Myocardial Ischaemia Hospitalization 9/28/2006 68 Female 115 lb 1/4/2007 Other Health Professional Poland
Primary
Secondary
Concomitant
Presyncope Hospitalization 9/8/2006 Male 209 lb 11/4/2006 Pharmacist United States
Primary
Concomitant
Myalgia Other Serious 11/20/2006 61 Male 170 lb 11/20/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 11/24/2006 69 Male 154 lb 1/29/2007 Romania
Primary
Secondary
Concomitant
Fatigue 1/1/2006 83 Male 210 lb 11/7/2006 Physician United States
Primary
Concomitant
Shock Other Serious 11/26/2006 70 Male 3/28/2007 Other Health Professional Sweden
Primary
Concomitant
Delirium Other Serious 3/13/2007 70 Male 169 lb 3/28/2007 Pharmacist United States
Primary
Concomitant
Venous Insufficiency Other Serious 1/1/2006 60 Male 4/27/2007 Physician United Kingdom
Primary
Concomitant
Hallucination Hospitalization 1/2/2007 60 Male 5/9/2007 Pharmacist United States
Primary
Concomitant
Sudden Death Death 1/1/2007 77 154 lb 5/7/2007 Other Health Professional United Kingdom
Primary
Concomitant
Treatment Noncompliance Other Serious 6/20/2007 65 Male 7/3/2007 Consumer United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 72 Male 159 lb 7/19/2007 Other Health Professional United States
Primary
Concomitant
Interacting
Pancytopenia Required Intervention 2/20/2007 80 Male 131 lb 6/20/2007 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 6/20/2007 77 Male 162 lb 8/9/2007 Pharmacist United States
Primary
Secondary
Concomitant
Dermatitis Exfoliative Other Serious 58 Male 9/13/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 72 Male 159 lb 9/25/2007 Pharmacist United States
Primary
Secondary
Concomitant
Angina Unstable Hospitalization 5/12/2006 65 Male 8/6/2007 Physician United States
Primary
Concomitant
Vertigo Hospitalization 10/25/2007 65 Female 167 lb 11/7/2007 Physician Hungary
Primary
Secondary
Concomitant
Tachycardia Other Serious 9/21/2007 Female 11/9/2007 Physician China
Primary
Concomitant
Pyrexia Hospitalization 11/2/2007 11/19/2007 Australia
Primary
Secondary
Concomitant
Arrhythmia Hospitalization 7/17/2007 77 Female 159 lb 11/29/2007 Greece
Primary
Concomitant
Vaginal Haemorrhage 9/3/2007 65 Female 11/16/2007 United States
Primary
Concomitant
Tibia Fracture Other Serious 9/7/2007 50 Male 249 lb 12/26/2007 Physician United Kingdom
Primary
Concomitant
Tibia Fracture Other Serious 9/7/2007 50 Male 249 lb 12/27/2007 Physician United Kingdom
Primary
Concomitant
Tibia Fracture Other Serious 9/8/2007 50 Male 249 lb 1/16/2008 Consumer United Kingdom
Primary
Concomitant
Cough Other Serious 1/12/2007 57 Male 223 lb 11/29/2007 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 12/1/2006 57 Female 220 lb 11/29/2007 Consumer United States
Primary
Concomitant
Hypotension Other Serious 7/6/2007 50 Male 2/15/2008 Physician Philippines
Primary
Secondary
Concomitant
Tibia Fracture Hospitalization 9/8/2007 50 Male 249 lb 2/11/2008 United States
Primary
Concomitant
Death Death 8/14/2007 68 Male 112 lb 2/25/2008 Physician United States
Primary
Concomitant
Urinary Tract Infection 88 Female 103 lb 3/10/2008 United States
Primary
Concomitant
Sinus Congestion 1/17/2008 Female 3/15/2008 United States
Primary
Concomitant
Mass 1/1/2008 Female 114 lb 3/15/2008 Consumer United States
Primary
Concomitant
Seizure Anoxic Hospitalization 12/4/2007 87 Male 3/18/2008 Other Health Professional Sweden
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 5/31/2007 3/11/2008 Other Health Professional United States
Primary
Concomitant
Mental Status Changes Required Intervention 2/17/2008 80 Female 141 lb 2/18/2008 Pharmacist United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 1/17/2007 Male 197 lb 3/28/2008 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization Female 103 lb 3/10/2008 Consumer United States
Primary
Concomitant
Constipation Hospitalization 3/23/2008 70 Male 4/10/2008 Physician Sweden
Primary
Concomitant
Constipation Hospitalization 3/23/2008 70 Male 4/18/2008 Physician Sweden
Primary
Concomitant
Cardiomyopathy Hospitalization 68 Female 4/18/2008 Physician Czech Republic
Primary
Secondary
Concomitant
Hypotension Other Serious 7/6/2007 Male 4/21/2008 Philippines
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 3/16/2002 45 Male 302 lb 4/29/2008 Consumer United States
Primary
Concomitant
Cardio-respiratory Arrest Death 12/15/2003 Male 231 lb 5/13/2008 Poland
Primary
Concomitant
Haemoglobin Decreased Hospitalization 3/23/2008 70 Male 5/20/2008 Physician Sweden
Primary
Concomitant
Constipation Hospitalization 3/23/2008 70 Male 5/23/2008 Physician Sweden
Primary
Concomitant
Blood Glucose Increased Other Serious 5/15/2008 Female 140 lb 5/30/2008 Consumer United States
Primary
Concomitant
Drug Level Increased 4/25/2008 Female 235 lb 5/30/2008 Other Health Professional United States
Primary
Concomitant
Oral Discomfort 4/15/2008 Female 138 lb 6/12/2008 Consumer United States
Primary
Concomitant
Oral Intake Reduced Hospitalization 86 Male 6/22/2008 United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 86 Male 6/22/2008 United States
Primary
Secondary
Nausea Hospitalization 86 Male 6/22/2008 United States
Primary
Secondary
Concomitant
Haematuria Other Serious 6/3/2003 Male 7/7/2008 Other Health Professional Sweden
Primary
Concomitant
Interacting
Febrile Neutropenia Hospitalization 5/26/2008 60 Male 210 lb 7/8/2008 United States
Primary
Secondary
Concomitant
Constipation Hospitalization 3/1/2008 70 Male 7/21/2008 Physician Sweden
Primary
Concomitant
Nausea Hospitalization 86 Male 7/21/2008 United States
Primary
Secondary
Concomitant
Nausea Hospitalization 86 Male 7/23/2008 Other Health Professional United States
Primary
Secondary
Cerebrovascular Accident Hospitalization 5/25/2007 80 Male 7/29/2008 Physician United States
Primary
Concomitant
Thirst 5/8/2008 61 Female 202 lb 7/7/2008 Consumer United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 5/26/2008 60 Male 209 lb 8/19/2008 United States
Primary
Secondary
Concomitant
Weight Decreased 12/1/2007 62 Female 132 lb 7/7/2008 Consumer United States
Primary
Concomitant
Wound Infection Staphylococcal Hospitalization 5/22/2008 48 Male 8/27/2008 Sweden
Primary
Concomitant
Swelling Face 5/12/2008 Female 249 lb 8/27/2008 Other Health Professional United States
Primary
Concomitant
Upper Limb Fracture Hospitalization 5/26/2008 Female 99 lb 9/3/2008 United Kingdom
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 7/8/2008 Female 191 lb 9/5/2008 Other Health Professional United States
Primary
Concomitant
Injection Site Nodule 8/27/2008 Female 327 lb 9/13/2008 United States
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 9/17/2008 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 9/10/2008 Female 226 lb 9/22/2008 Physician Hungary
Primary
Secondary
Concomitant
Nausea Hospitalization 86 Male 6/2/2008 Physician United States
Primary
Concomitant
Sick Sinus Syndrome Hospitalization 10/6/2006 74 Male 9/25/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/10/2008 Female 9/25/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Viral Infection Hospitalization 9/10/2008 Female 10/3/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 3/16/2002 45 Male 302 lb 10/14/2008 Consumer United States
Primary
Concomitant
Vitreous Haemorrhage Required Intervention 2/9/2003 84 Male 10/22/2008 Denmark
Primary
Concomitant
Respiratory Distress Hospitalization 10/12/2008 Female 10/31/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Viral Pharyngitis Hospitalization 10/12/2008 Female 11/7/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 10/21/2008 82 Female 216 lb 11/6/2008 Physician Sweden
Primary
Concomitant
Tendon Rupture Hospitalization 9/11/2008 Male 11/14/2008 Pharmacist United States
Primary
Concomitant
Pain In Extremity Male 11/26/2008 United States
Primary
Concomitant
Rash Erythematous Female 11/26/2008 United States
Primary
Concomitant
Melanosis Coli Other Serious 71 Male 11/27/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Hospitalization 8/25/2008 65 Female 11/11/2008 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/1/2008 Female 11/25/2008 Consumer United States
Primary
Concomitant
Vascular Pseudoaneurysm Hospitalization 11/8/2008 82 Male 146 lb 11/21/2008 United States
Primary
Secondary
Concomitant
Product Quality Issue Hospitalization 9/1/2008 85 Female 142 lb 11/25/2008 Consumer United States
Primary
Concomitant
Renal Impairment Life Threatening 86 Male 12/2/2008 Physician United States
Primary
Secondary
Concomitant
Product Quality Issue Other Serious 11/1/2008 66 Female 165 lb 12/3/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 3/4/2008 79 Female 12/8/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Death 11/21/2008 86 Male 180 lb 12/15/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 4/25/2007 53 Male 147 lb 12/16/2008 Consumer United States
Primary
Concomitant
Haemoglobin Abnormal Other Serious 4/11/2007 Male 12/22/2008 Philippines
Primary
Concomitant
Product Quality Issue Hospitalization 10/1/2008 40 Male 12/17/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Other Serious 2/28/2008 83 Female 12/19/2008 Consumer United States
Primary
Concomitant
Tremor Hospitalization 10/28/2008 75 Female 156 lb 12/22/2008 Consumer United States
Primary
Concomitant
Renal Failure Death 1/1/2006 79 Female 12/22/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Other Serious 1/1/2007 57 Male 248 lb 12/22/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 5/7/2008 71 Female 106 lb 12/22/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Other Serious 1/1/2003 79 Female 180 lb 12/23/2008 Consumer United States
Primary
Secondary
Concomitant
Product Quality Issue Hospitalization 11/1/2008 54 Male 174 lb 12/30/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 10/1/2008 47 Female 134 lb 12/30/2008 Consumer United States
Primary
Concomitant

Drug Data