Isosorbide Mononitrate combined with Lorazepam

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Myocardial Infarction Other Serious 6/1/2001 80 Female 146 lb 1/30/2006 Lawyer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 7/12/2005 Female 2/28/2006 Consumer United States
Primary
Concomitant
Contusion Hospitalization 3/17/2004 53 Female 190 lb 12/27/2005 Consumer United States
Primary
Concomitant
Renal Failure Acute Required Intervention 8/24/2006 57 Male 290 lb 8/24/2006 Pharmacist United States
Primary
Concomitant
Pruritus Other Serious Female 8/29/2006 United States
Primary
Secondary
Concomitant
Panic Attack Hospitalization 9/3/2006 63 Male 258 lb 10/5/2006 Germany
Primary
Concomitant
Tremor Other Serious 3/1/2006 66 Female 140 lb 11/16/2006 Physician United States
Primary
Concomitant
Melaena Hospitalization 11/7/2006 79 Female 4/9/2007 Physician France
Primary
Secondary
Concomitant
Rash Required Intervention 7/9/2007 47 Female 188 lb 7/18/2007 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 6/20/2007 77 Male 162 lb 8/9/2007 Pharmacist United States
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 68 Female 10/22/2007 United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 12/11/2007 Female 1/24/2008 Physician United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 9/1/2007 Male 114 lb 12/5/2007 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased 1/1/2007 61 Male 175 lb 12/5/2007 Physician United States
Primary
Concomitant
Vomiting 1/30/2008 66 Female 170 lb 3/11/2008 Physician United States
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 87 Male 3/17/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 12/11/2007 Female 3/21/2008 Physician United States
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 87 Male 3/28/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 87 Male 3/27/2008 United Kingdom
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 87 Male 3/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 87 Male 3/31/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 12/11/2007 73 Female 7/29/2008 Consumer France
Primary
Secondary
Concomitant
Productive Cough 2/1/2008 67 Female 8/15/2008 United States
Primary
Concomitant
Angina Pectoris Hospitalization 10/10/2008 Male 11/20/2008 Canada
Primary
Concomitant
Troponin Increased Other Serious 1/1/2003 78 Male 140 lb 1/8/2009 United States
Primary
Concomitant
Troponin Increased Other Serious 1/1/2003 78 Male 140 lb 4/14/2009 United States
Primary
Concomitant
Vision Blurred Other Serious 5/1/2002 47 Female 255 lb 7/23/2009 United States
Primary
Secondary
Concomitant
Type 1 Diabetes Mellitus Other Serious 7/25/2006 59 Male 296 lb 8/12/2009 United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 8/5/2009 53 Female 287 lb 9/5/2009 Pharmacist United States
Primary
Secondary
Concomitant
Unevaluable Event Disability 7/1/2009 75 Female 142 lb 9/8/2009 Physician United States
Primary
Concomitant
Tuberculous Pleurisy Life Threatening 9/9/2007 Male 143 lb 9/22/2009 Physician Thailand
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1999 53 Male 9/23/2009 United States
Primary
Concomitant
Tuberculous Pleurisy Life Threatening 9/9/2007 Male 143 lb 11/3/2009 Physician Thailand
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2009 65 Male 201 lb 11/30/2009 Physician United States
Primary
Concomitant
Myalgia Death 1/1/2009 Male 11/25/2009 Consumer United States
Primary
Concomitant
Sepsis Life Threatening 11/21/2009 Male 161 lb 12/16/2009 Physician India
Primary
Secondary
Concomitant
Sepsis Life Threatening 11/21/2009 Male 161 lb 12/23/2009 Physician India
Primary
Secondary
Concomitant
Sepsis Life Threatening 11/21/2009 Male 161 lb 12/28/2009 Physician India
Primary
Secondary
Concomitant
Sepsis Life Threatening 11/21/2009 Male 161 lb 12/29/2009 Physician India
Primary
Secondary
Concomitant
Myalgia Death 1/1/2009 Male 12/23/2009 Physician United States
Primary
Concomitant
Sepsis Life Threatening 11/21/2009 Male 161 lb 1/6/2010 Physician India
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 56 Male 1/8/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Sputum Discoloured Other Serious 56 Male 1/8/2010 United Kingdom
Primary
Concomitant
Sputum Discoloured Hospitalization 1/1/2009 56 Male 1/14/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2010 88 Female 1/27/2010 Consumer Canada
Primary
Concomitant
Vitrectomy Other Serious 3/1/2006 Male 2/10/2010 Physician United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 Male 3/4/2010 Lawyer United States
Primary
Concomitant
Vomiting Life Threatening 12/14/2007 69 Male 3/4/2010 Lawyer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/21/2009 74 Male 161 lb 4/1/2010 Physician India
Primary
Secondary
Concomitant
Sepsis Life Threatening 11/21/2009 74 Male 161 lb 4/12/2010 Physician India
Primary
Secondary
Concomitant
Sepsis Life Threatening 11/21/2009 74 Male 161 lb 5/20/2010 Physician India
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 6/3/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/2/2007 69 Male 187 lb 6/7/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2008 61 Male 6/22/2010 Lawyer United States
Primary
Concomitant
Vision Blurred Other Serious 1/4/2008 72 Male 7/13/2010 Lawyer United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 4/25/2007 57 Female 145 lb 7/13/2010 Consumer United States
Primary
Concomitant
Thyroid Function Test Abnormal 2/20/2007 76 Female 101 lb 7/14/2010 Other Health Professional United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Vision Blurred Life Threatening 7/22/2010 54 Female 7/25/2010 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2008 61 Male 187 lb 8/19/2010 Other Health Professional United States
Primary
Concomitant
Sepsis Life Threatening 11/21/2009 74 Male 161 lb 8/26/2010 Physician India
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 11/21/2009 74 Male 161 lb 8/27/2010 Physician India
Primary
Secondary
Concomitant
Sepsis Life Threatening 11/21/2009 74 Male 161 lb 9/2/2010 Physician India
Primary
Secondary
Concomitant
Oesophageal Stenosis Hospitalization Male 9/9/2010 Physician Netherlands
Primary
Concomitant
Vision Blurred Other Serious 1/1/2008 72 Male 214 lb 9/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 12/7/1999 53 Male 9/17/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1999 53 Male 400 lb 9/21/2010 United States
Primary
Concomitant
Vomiting Other Serious 12/14/2007 69 Male 187 lb 10/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Condition Aggravated Other Serious 45 Female 10/12/2010 Physician
Primary
Secondary
Concomitant
Mental Disorder Other Serious 45 Female 10/13/2010 Physician United States
Primary
Secondary
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 10/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea 1/1/2010 64 Female 148 lb 10/28/2010 Physician United States
Primary
Concomitant
Mental Disorder Other Serious 45 Female 10/29/2010 Physician United States
Primary
Secondary
Mental Disorder Other Serious 45 Female 10/29/2010 Physician United States
Primary
Secondary
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 11/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Mental Disorder Hospitalization 45 Female 11/3/2010 Physician United States
Primary
Secondary
Vision Blurred Other Serious 1/1/2008 72 Male 214 lb 11/8/2010 Lawyer United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 9/17/2010 72 Male 180 lb 11/2/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2008 61 Male 187 lb 11/18/2010 Other Health Professional United States
Primary
Concomitant
Aplasia Pure Red Cell Other Serious 10/1/2009 70 Female 11/18/2010 Physician United States
Primary
Secondary
Concomitant
Mental Disorder Other Serious 45 Female 11/24/2010 Physician United States
Primary
Secondary
Mental Disorder Hospitalization 45 Female 11/8/2010 United States
Primary
Secondary
Mental Disorder Hospitalization 45 Female 12/1/2010 Other Health Professional United States
Primary
Secondary
Vomiting Other Serious 1/1/2008 72 Male 214 lb 12/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 9/17/2010 72 Male 180 lb 11/30/2010 United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 11/3/2010 54 Female 183 lb 12/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Screen Negative Hospitalization 12/1/2010 92 Male 1/5/2011 Pharmacist United States
Primary
Concomitant
Staphylococcal Infection Other Serious 11/3/2010 54 Female 183 lb 1/10/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Generalised Other Serious 1/1/2008 72 Male 214 lb 1/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/14/2007 69 Male 187 lb 1/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Depression Other Serious 9/10/2008 54 Male 2/10/2011 Lawyer United States
Primary
Concomitant
Arrhythmia Other Serious 12/1/2007 54 Male 163 lb 4/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Radiotherapy Other Serious 78 Female 157 lb 4/22/2011 Other Health Professional United States
Primary
Concomitant
Dystonia Other Serious 7/1/2009 58 Female 175 lb 5/23/2011 Lawyer United States
Primary
Concomitant
Disturbance In Attention Disability 1/1/2009 70 Female 181 lb 5/24/2011 Physician United States
Primary
Concomitant
Angina Unstable Other Serious Male 6/13/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 5/1/2011 62 Male 250 lb 6/15/2011 Other Health Professional United States
Primary
Concomitant
Haematuria Hospitalization 6/11/2011 55 Female 238 lb 6/17/2011 Pharmacist United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 5/1/2011 62 Male 250 lb 6/22/2011 Consumer United States
Primary
Concomitant
Heart Valve Calcification Disability 78 Female 157 lb 7/18/2011 Consumer United States
Primary
Concomitant
Thrombocytopenia Death 12/1/2007 54 Male 163 lb 7/22/2011 Lawyer United States
Primary
Secondary
Concomitant
Cardiac Output Decreased Other Serious 12/1/2007 54 Male 163 lb 7/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Oedema Other Serious Male 8/4/2011 Physician United States
Primary
Concomitant
Intervertebral Disc Degeneration Other Serious Male 8/8/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Hospitalization 6/1/2011 78 Female 157 lb 8/9/2011 United States
Primary
Concomitant
Acute Myocardial Infarction Other Serious 8/17/2011 Other Health Professional United States
Primary
Concomitant
Arteriospasm Coronary Other Serious 8/19/2011 Other Health Professional United States
Primary
Concomitant
Arteriospasm Coronary Other Serious 8/22/2011 Physician United States
Primary
Secondary
Concomitant
Scoliosis Disability 1/1/2007 72 Female 220 lb 8/22/2011 Lawyer United States
Primary
Concomitant
Arteriospasm Coronary Other Serious 47 Female 9/17/2011 Physician United States
Primary
Secondary
Concomitant
Chest Pain Other Serious 47 Female 9/21/2011 Other Health Professional United States
Primary
Concomitant
Subendocardial Ischaemia Other Serious 9/26/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Multiple Myeloma Death Female 211 lb 9/26/2011 Physician United States
Primary
Secondary
Concomitant
Hyperparathyroidism Hospitalization Male 10/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Electrocardiogram St-t Change Other Serious Male 10/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 9/22/2011 73 Female 10/19/2011 Physician United States
Primary
Concomitant
Constipation Hospitalization 5/5/2009 56 Male 10/24/2011 Physician United States
Primary
Secondary
Concomitant
Dyspepsia Hospitalization 7/24/2007 69 Female 133 lb 10/24/2011 Consumer United States
Primary
Secondary
Concomitant
Anaemia Life Threatening 69 Male 187 lb 10/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Blister Other Serious 10/19/2011 65 Female 136 lb 11/7/2011 Other Health Professional United Kingdom
Primary
Concomitant
Blister Other Serious 10/19/2011 65 Female 136 lb 11/2/2011 United Kingdom
Primary
Concomitant
Pneumonia Other Serious 9/2/2011 74 Male 177 lb 11/15/2011 Physician United States
Primary
Concomitant
Cholelithiasis Death 12/1/2007 54 Male 163 lb 11/16/2011 Lawyer United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 62 Male 11/17/2011 Consumer United States
Primary
Concomitant
Hyponatraemia Hospitalization 10/12/2011 72 Female 171 lb 11/28/2011 Other Health Professional Netherlands
Primary
Concomitant
Skin Haemorrhage Other Serious 49 Male 1/5/2012 Pharmacist United States
Primary
Concomitant
Neuralgia Hospitalization 7/24/2007 73 Female 133 lb 1/17/2012 United States
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 11/18/2011 77 Female 1/18/2012 Physician Italy
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/1/2009 56 Male 1/23/2012 Consumer United States
Primary
Secondary
Concomitant
Sputum Discoloured Hospitalization 1/1/2009 56 Male 1/23/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cyanosis Hospitalization 1/1/2009 56 Male 2/6/2012 Consumer United States
Primary
Secondary
Concomitant
Cholelithiasis Hospitalization 1/29/2012 82 Female 1/31/2012 United States
Primary
Concomitant
Drug Ineffective Other Serious 11/18/2011 77 Female 2/14/2012 Physician Italy
Primary
Secondary
Concomitant
Lymphocyte Count Decreased Other Serious 5/5/2009 56 Male 2/15/2012 Consumer United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Death Female 3/1/2012 Physician United States
Primary
Concomitant
Mental Status Changes Death 9/2/2011 74 Male 177 lb 3/2/2012 Physician United States
Primary
Concomitant
Erythrodermic Psoriasis Hospitalization 8/21/2011 64 Female 129 lb 4/6/2012 Other Health Professional United Kingdom
Primary
Concomitant
Skin Tightness Other Serious 3/3/2012 86 Female 143 lb 4/19/2012 Other Health Professional United Kingdom
Primary
Concomitant
Somatic Delusion Hospitalization 8/21/2011 64 Female 129 lb 5/11/2012 Other Health Professional United Kingdom
Primary
Concomitant
Neoplasm Malignant Death Male 5/14/2012 Consumer United States
Primary
Concomitant
Neutrophil Count Increased Other Serious 5/5/2009 56 Male 5/15/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 9/15/2011 88 Female 5/18/2012 Pharmacist Spain
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 1/28/2010 75 Male 5/25/2012 Physician Thailand
Primary
Concomitant
Gastrooesophageal Reflux Disease Other Serious 65 Male 116 lb 6/5/2012 Consumer United States
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 47 Female 6/22/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 5/16/2012 65 Female 6/27/2012 Consumer United States
Primary
Secondary
Loss Of Consciousness Hospitalization 5/16/2012 65 Female 6/27/2012 Consumer United States
Primary
Secondary
Loss Of Consciousness Hospitalization Female 6/28/2012 Consumer United States
Primary
Secondary
Diarrhoea Other Serious 4/1/2012 56 Female 7/12/2012 Consumer United States
Primary
Concomitant
Osteomyelitis Hospitalization 5/5/2009 56 Male 7/19/2012 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data