Isosorbide Mononitrate combined with Levothyroxine Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pancreatitis Acute Other Serious 1/7/2006 74 Male 1/18/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Chronic Life Threatening 12/11/2005 84 Female 88 lb 1/23/2006 Physician Japan
Primary
Concomitant
Pneumonitis Death 6/1/2005 69 Male 1/30/2006 United Kingdom
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United States
Primary
Concomitant
Pneumonitis Death 6/1/2005 69 Male 2/6/2006 United Kingdom
Primary
Concomitant
Myocardial Infarction Other Serious 5/15/2003 76 Female 77 lb 2/21/2006 Lawyer United Kingdom
Primary
Concomitant
Renal Failure Chronic Life Threatening 12/11/2005 84 Female 88 lb 2/13/2006 Physician Japan
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/23/2006 United States
Primary
Concomitant
Vomiting Other Serious 8/1/2001 76 Female 99 lb 2/24/2006 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 8/1/2001 76 Female 99 lb 3/2/2006 Physician United Kingdom
Primary
Concomitant
Factor V Leiden Mutation Hospitalization 2/17/2006 85 Male 187 lb 3/14/2006 Pharmacist United States
Primary
Concomitant
Rash Pruritic Other Serious 1/30/2005 75 Female 165 lb 12/21/2005 Consumer United States
Primary
Concomitant
Osteoarthritis Hospitalization 1/1/2003 60 Female 150 lb 4/4/2006 Lawyer United States
Primary
Concomitant
Myalgia Other Serious 7/22/2005 51 Male 227 lb 4/13/2006 Pharmacist United States
Primary
Concomitant
Hallucination, Visual Hospitalization 10/28/2005 79 Male 148 lb 4/18/2006 Physician Canada
Primary
Concomitant
Fall Other Serious 2/1/2006 92 Male 4/26/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 1/7/2004 50 Female 5/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Fall Other Serious 2/1/2006 92 Male 5/23/2006 Japan
Primary
Secondary
Concomitant
Non-cardiac Chest Pain Hospitalization 2/23/2006 77 Female 6/23/2006 Physician United Kingdom
Primary
Concomitant
Non-cardiac Chest Pain Other Serious 2/23/2006 77 Female 6/27/2006 Physician United Kingdom
Primary
Concomitant
Renal Impairment Disability 4/7/2006 77 Male 128 lb 7/21/2006 Physician Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 5/5/2001 77 Male 7/21/2006 United States
Primary
Concomitant
Multi-organ Failure Other Serious 7/2/2006 77 Female 99 lb 7/21/2006 Physician United Kingdom
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 6/12/2006 55 Female 8/9/2006 United States
Primary
Concomitant
Ischaemic Stroke Life Threatening 5/29/2006 86 Female 8/25/2006 United Kingdom
Primary
Secondary
Concomitant
Pruritus Other Serious Female 8/29/2006 United States
Primary
Secondary
Concomitant
Intracranial Aneurysm Hospitalization 6/21/2006 Male 9/11/2006 Pharmacist United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/13/2006 77 Male 311 lb 10/4/2006 Pharmacist United States
Primary
Concomitant
Nodal Rhythm Hospitalization 9/25/2006 80 Female 10/16/2006 Physician Poland
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 1/1/2005 65 Female 180 lb 11/1/2006 United States
Primary
Concomitant
Fatigue 1/1/2005 81 Female 205 lb 11/13/2006 Consumer United States
Primary
Concomitant
Renal Impairment Disability 4/7/2006 77 Male 128 lb 11/20/2006 Physician Japan
Primary
Concomitant
Lung Infiltration Life Threatening 9/7/2006 Female 12/7/2006 Physician Finland
Primary
Concomitant
Neutropenia Hospitalization 12/4/2006 Female 176 lb 12/5/2006 Pharmacist United States
Primary
Concomitant
Pulmonary Tuberculosis Life Threatening 9/7/2006 Female 12/15/2006 Physician Finland
Primary
Concomitant
Pulmonary Tuberculosis Life Threatening 9/7/2006 Female 12/20/2006 Physician Finland
Primary
Concomitant
Pallor Hospitalization 10/15/2006 84 Female 12/19/2006 United Kingdom
Primary
Secondary
Concomitant
Nausea Other Serious 11/14/2006 71 Female 1/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tremor 1/1/2006 78 Male 233 lb 10/19/2006 United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 12/8/2005 73 Male 1/30/2007 United Kingdom
Primary
Concomitant
Vertigo Other Serious 12/29/2006 83 Female 169 lb 2/9/2007
Primary
Concomitant
Nausea Hospitalization 9/25/2006 80 Female 2/12/2007 Poland
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 12/1/2006 Male 155 lb 3/27/2007 Consumer United States
Primary
Concomitant
Low Density Lipoprotein Decreased Other Serious 62 Male 11/28/2006 United States
Primary
Concomitant
Retinopathy Other Serious 3/1/2006 Female 4/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Liver Disorder Other Serious 1/5/2007 55 Male 4/12/2007 Japan
Primary
Concomitant
Vision Blurred Hospitalization 12/1/2006 Male 155 lb 5/14/2007 Consumer United States
Primary
Concomitant
Retinopathy Other Serious 3/1/2006 Female 5/14/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Diabetic Retinopathy Other Serious 3/1/2006 Female 5/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 84 Female 181 lb 5/14/2007 Other Health Professional United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 5/24/2007 Female 119 lb 6/8/2007 Other Health Professional United States
Primary
Concomitant
Septic Shock Hospitalization 6/13/2007 Female 6/29/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Septic Shock Hospitalization 6/13/2007 Female 7/11/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 6/7/2007 89 Female 7/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 6/7/2007 89 Female 7/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Orthostatic Hypotension Hospitalization 6/7/2007 89 Female 7/27/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 89 Female 7/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 6/7/2007 89 Female 7/18/2007 United Kingdom
Primary
Secondary
Concomitant
Normochromic Normocytic Anaemia Other Serious 75 8/8/2007 Physician United Kingdom
Primary
Concomitant
Myocardial Infarction Life Threatening 6/14/2007 73 Female 168 lb 8/15/2007 Physician United Kingdom
Primary
Concomitant
Drug Interaction Death 82 Female 8/16/2007 Sweden
Primary
Concomitant
Interacting
Drug Interaction Death 77 Female 8/16/2007 Sweden
Primary
Concomitant
Interacting
Myocardial Infarction Life Threatening 6/14/2007 73 Female 168 lb 8/22/2007 Physician United Kingdom
Primary
Concomitant
Normochromic Normocytic Anaemia Other Serious 7/26/2007 75 Female 119 lb 8/23/2007 Physician United Kingdom
Primary
Concomitant
Lichen Planus Other Serious 3/1/2007 68 Female 9/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Muscle Spasms Hospitalization 8/15/2007 83 Female 10/12/2007 Consumer United Kingdom
Primary
Concomitant
Head Injury Hospitalization 6/17/2007 Female 120 lb 10/22/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Hypnagogic Hallucination Other Serious 12/1/2005 66 Male 11/1/2007 Other Health Professional United Kingdom
Primary
Concomitant
Head Injury Hospitalization 6/17/2007 Female 120 lb 11/13/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Cholelithiasis Hospitalization 5/22/2007 Female 110 lb 11/19/2007 United Kingdom
Primary
Concomitant
Muscle Spasms Hospitalization 8/15/2007 83 Female 11/21/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 68 Female 10/22/2007 United States
Primary
Secondary
Concomitant
Application Site Dermatitis Other Serious 10/12/2007 87 Female 11/29/2007 Physician United Kingdom
Primary
Concomitant
Palpitations Other Serious 9/1/2007 56 Female 12/5/2007 Consumer Australia
Primary
Concomitant
Ventricular Tachycardia Death 3/5/2007 88 Female 156 lb 12/7/2007 Pharmacist United States
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 54 Male 12/17/2007 Australia
Primary
Secondary
Concomitant
Abdominal Wall Abscess Hospitalization 3/29/2007 Female 134 lb 12/28/2007 United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2006 73 Male 120 lb 12/3/2007 Consumer United States
Primary
Secondary
Concomitant
Rash Pruritic Disability 2/1/2008 71 Female 143 lb 2/29/2008 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting 1/30/2008 66 Female 170 lb 3/11/2008 Physician United States
Primary
Concomitant
Mass 1/1/2008 Female 114 lb 3/15/2008 Consumer United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 3/28/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Rhabdomyolysis Life Threatening 77 Female 3/31/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 4/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 4/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 3/28/2008 United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 77 Female 3/29/2008 United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 77 Female 4/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Constipation Hospitalization 3/23/2008 70 Male 4/10/2008 Physician Sweden
Primary
Concomitant
Constipation Hospitalization 3/23/2008 70 Male 4/18/2008 Physician Sweden
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 4/18/2008 United States
Primary
Concomitant
Myocardial Ischaemia Life Threatening 8/30/2005 Male 139 lb 4/22/2008 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 4/30/2008 United States
Primary
Concomitant
Bradycardia Hospitalization 11/29/2007 Female 196 lb 5/8/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 5/9/2008 United States
Primary
Concomitant
Vomiting Other Serious 1/14/2004 50 Female 5/9/2008 United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 5/15/2008 United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization 3/23/2008 70 Male 5/20/2008 Physician Sweden
Primary
Concomitant
Constipation Hospitalization 3/23/2008 70 Male 5/23/2008 Physician Sweden
Primary
Concomitant
Bradycardia Hospitalization 11/29/2007 Female 196 lb 6/4/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 1/14/2004 50 Female 6/18/2008 United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 8/30/2005 Male 139 lb 6/27/2008 United States
Primary
Concomitant
Constipation Hospitalization 3/1/2008 70 Male 7/21/2008 Physician Sweden
Primary
Concomitant
Nausea Hospitalization 1/2/2008 Female 7/23/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Other Serious 6/16/2008 75 Male 8/6/2008 Other Health Professional Croatia (Local Name: Hrvatska)
Primary
Secondary
Concomitant
Retinal Injury Other Serious 4/1/2008 80 Female 8/6/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Macular 7/11/2008 Female 8/29/2008 United States
Primary
Concomitant
Speech Disorder Other Serious 7/19/2008 60 Female 9/1/2008 Portugal
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 9/17/2008 Lawyer United States
Primary
Concomitant
Palpitations Other Serious 64 Female 9/19/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Sciatica Other Serious 8/7/2007 74 Female 198 lb 10/10/2008 Physician Australia
Primary
Concomitant
Withdrawal Syndrome Other Serious 9/22/2008 82 Female 11/24/2008 Physician Germany
Primary
Secondary
Concomitant
Melanosis Coli Other Serious 71 Male 11/27/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hypomagnesaemia Other Serious Female 12/5/2008 Physician United Kingdom
Primary
Concomitant
Product Quality Issue 9/17/2008 Male 225 lb 12/12/2008 United States
Primary
Concomitant
Catheter Site Infection 10/12/2008 Female 169 lb 12/12/2008 United States
Primary
Concomitant
Haemoglobin Decreased 9/1/2008 Female 250 lb 12/12/2008 United States
Primary
Secondary
Concomitant
Product Quality Issue Hospitalization 1/1/2008 63 Male 12/9/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 6/1/2008 76 Female 125 lb 12/10/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Death 5/1/2008 65 Male 225 lb 12/15/2008 Consumer United States
Primary
Concomitant
Upper Limb Fracture Hospitalization 1/1/2006 77 Female 12/16/2008 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 8/4/2008 77 Female 155 lb 12/18/2008 Consumer United States
Primary
Concomitant
Syncope Hospitalization 1/1/2008 79 Female 12/22/2008 Consumer United States
Primary
Concomitant
Vascular Graft Hospitalization 10/24/2008 72 Male 227 lb 12/30/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Other Serious 10/1/2008 67 Male 205 lb 1/30/2009 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 9/1/2007 77 Female 140 lb 1/29/2009 Consumer United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 2/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Rhabdomyolysis Hospitalization 77 Female 2/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 77 Female 2/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tardive Dyskinesia Other Serious 86 Female 2/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Tardive Dyskinesia Other Serious 86 Female 2/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Flushing 11/19/2008 Female 2/24/2009 United States
Primary
Concomitant
Product Quality Issue Other Serious 10/25/2008 75 Female 118 lb 2/25/2009 Physician United Kingdom
Primary
Concomitant
Tardive Dyskinesia Disability 1/23/2009 86 Female 2/20/2009 United Kingdom
Primary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 2/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 11/1/2008 40 Female 2/23/2009 Consumer United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 3/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 3/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 77 Female 3/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 77 Female 3/23/2009 United Kingdom
Primary
Secondary
Concomitant
Sensation Of Pressure Hospitalization 6/1/2008 64 Female 153 lb 3/13/2009 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 11/1/2008 70 Male 3/20/2009 Consumer United States
Primary
Concomitant
Hemiparesis Hospitalization 7/8/2008 Male 206 lb 3/31/2009 Physician United States
Primary
Concomitant
Rhabdomyolysis Other Serious 77 Female 4/7/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 77 Female 4/7/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 77 Female 4/14/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 77 Female 4/15/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 77 Female 4/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Urinary Tract Infection Hospitalization 77 Female 4/10/2009 Physician United Kingdom
Primary
Secondary
Concomitant

Drug Data