Isosorbide Mononitrate combined with Lasix

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Respiratory Failure Hospitalization 2/23/2005 Female 121 lb 1/3/2006 Other Health Professional
Primary
Secondary
Concomitant
Interacting
Rectal Polyp Hospitalization 8/14/2005 64 Female 154 lb 12/30/2005 Physician United States
Primary
Concomitant
Muscle Disorder Hospitalization 12/25/2005 71 Male 1/11/2006 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 3/15/2000 56 Male 265 lb 1/19/2006 Physician United States
Primary
Concomitant
Pancreatitis Acute Other Serious 1/7/2006 74 Male 1/18/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Chronic Life Threatening 12/11/2005 84 Female 88 lb 1/23/2006 Physician Japan
Primary
Concomitant
Rectal Polyp Hospitalization 8/14/2005 64 Female 154 lb 1/20/2006 Physician United States
Primary
Concomitant
Rash 5/1/2005 64 Female 324 lb 1/30/2006 Consumer United States
Primary
Secondary
Concomitant
Somnolence Other Serious 79 Male 158 lb 1/31/2006 Physician Japan
Primary
Concomitant
Urine Output Decreased Hospitalization 11/19/2005 Male 208 lb 1/3/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 8/8/2002 59 Male 203 lb 2/13/2006 Physician United States
Primary
Concomitant
Renal Failure Chronic Life Threatening 12/11/2005 84 Female 88 lb 2/13/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 7/12/2005 Female 2/28/2006 Consumer United States
Primary
Concomitant
Mitral Valve Incompetence Other Serious 1/21/2004 77 Female 97 lb 3/3/2006 Physician Japan
Primary
Concomitant
Upper Respiratory Tract Inflammation Hospitalization 4/10/2002 60 Female 112 lb 3/29/2006 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Death 1/1/2005 92 Female 99 lb 3/21/2006 Physician United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 1/1/2001 64 Male 198 lb 3/30/2006 Physician United States
Primary
Concomitant
Haemolysis Other Serious 89 Male 3/23/2006 Pharmacist Japan
Primary
Concomitant
Rhabdomyolysis Other Serious 65 3/31/2006 Pharmacist Japan
Primary
Concomitant
Septic Shock Life Threatening 3/21/2005 76 Male 3/28/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Skin Inflammation Death 4/15/2005 83 Male 3/17/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Therapeutic Response Decreased Hospitalization 1/1/2005 Male 200 lb 4/10/2006 Consumer United States
Primary
Concomitant
Rash Other Serious 2/1/2006 70 Male 4/3/2006 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 2/26/2006 64 Female 195 lb 4/13/2006 Physician United States
Primary
Secondary
Concomitant
Rash Other Serious 2/1/2006 70 Male 4/7/2006 Physician United States
Primary
Concomitant
Hallucination Other Serious 4/4/2006 5/1/2006 Pharmacist Netherlands
Primary
Secondary
Concomitant
Syncope Other Serious 4/1/2006 67 Female 5/11/2006 Consumer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 9/29/2003 Male 5/16/2006 United States
Primary
Secondary
Concomitant
Acute Myocardial Infarction Death 36 Male 6/5/2006 Physician Japan
Primary
Secondary
Liver Disorder Hospitalization 3/8/2004 Female 177 lb 6/5/2006 Physician Japan
Primary
Secondary
Concomitant
Drug Effect Decreased 10/1/2005 63 Male 240 lb 4/3/2006 Consumer United States
Primary
Concomitant
Cholestasis Life Threatening 5/23/2006 77 Male 6/12/2006 Physician Japan
Primary
Concomitant
Weight Increased Hospitalization 4/1/2006 80 Male 6/15/2006 Physician Japan
Primary
Concomitant
Acute Myocardial Infarction Death 5/26/2006 36 Male 7/7/2006 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 3/8/2004 Female 177 lb 7/11/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 7/4/2006 Male 117 lb 7/26/2006 Physician Japan
Primary
Concomitant
Renal Impairment Disability 4/7/2006 77 Male 128 lb 7/21/2006 Physician Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 5/5/2001 77 Male 7/21/2006 United States
Primary
Concomitant
Hypotension Hospitalization 6/1/2006 Male 7/27/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Interacting
Tongue Oedema Other Serious 3/15/2006 87 Female 6/21/2006 United States
Primary
Concomitant
Tachycardia 2/2/2006 Male 180 lb 8/4/2006 Physician United States
Primary
Concomitant
Pancytopenia Hospitalization 6/30/2006 Male 8/3/2006 Other Health Professional Japan
Primary
Concomitant
Pulmonary Hypertension Other Serious 6/22/2006 45 Male 203 lb 8/9/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Erythema Multiforme Other Serious 1/19/2006 83 Female 8/15/2006 Physician Japan
Primary
Secondary
Concomitant
Lymphoma Life Threatening 8/1/2006 69 Male 253 lb 8/16/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Life Threatening 7/4/2006 Male 117 lb 8/30/2006 Physician Japan
Primary
Concomitant
Disseminated Intravascular Coagulation Life Threatening 7/16/2006 73 Male 121 lb 9/8/2006 Physician Japan
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Life Threatening 7/16/2006 73 Male 121 lb 9/14/2006 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 5/1/2006 45 Male 203 lb 9/14/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Sudden Death Death Male 9/14/2006 Physician Japan
Primary
Concomitant
Dyspnoea Hospitalization 3/7/2005 79 Female 9/15/2006 Consumer Japan
Primary
Concomitant
Visual Field Defect Other Serious 6/1/2006 58 Male 9/20/2006 Japan
Primary
Concomitant
Tongue Oedema Other Serious 62 Male 9/28/2006 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2006 62 Male 224 lb 9/29/2006 Physician United States
Primary
Concomitant
Rash Other Serious 1/19/2006 83 Female 150 lb 10/14/2006 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 8/23/2006 48 Male 168 lb 10/27/2006 Physician Japan
Primary
Concomitant
Staphylococcal Infection Other Serious 8/23/2006 48 Male 168 lb 11/9/2006 Physician Japan
Primary
Concomitant
Sudden Death Hospitalization 7/4/2005 Male 11/13/2006 Physician Japan
Primary
Concomitant
Sleep Disorder Hospitalization 3/1/2006 Male 11/20/2006 Consumer United States
Primary
Secondary
Concomitant
Tremor Other Serious Female 11/22/2006 Pharmacist Japan
Primary
Concomitant
Tremor Other Serious 81 Female 11/29/2006 Pharmacist Japan
Primary
Concomitant
Tremor Other Serious 3/1/2006 66 Female 140 lb 11/16/2006 Physician United States
Primary
Concomitant
Renal Failure Acute Life Threatening 7/4/2006 Male 117 lb 11/29/2006 Physician Japan
Primary
Concomitant
Renal Impairment Disability 4/7/2006 77 Male 128 lb 11/20/2006 Physician Japan
Primary
Concomitant
Staphylococcal Infection Other Serious 8/23/2006 Male 168 lb 12/5/2006 Physician Japan
Primary
Concomitant
Tremor Other Serious 81 Female 1/3/2007 Pharmacist Japan
Primary
Concomitant
Tremor 1/1/2006 78 Male 233 lb 10/19/2006 United States
Primary
Concomitant
Syncope Other Serious 71 Male 1/17/2007 Pharmacist United States
Primary
Concomitant
Pharmaceutical Product Complaint 2/1/2007 56 Female 320 lb 2/23/2007 Other Health Professional United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/8/2007 56 Female 320 lb 3/2/2007 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/8/2007 56 Female 320 lb 3/12/2007 Consumer United States
Primary
Concomitant
Renal Disorder Hospitalization 2/16/2007 51 Female 3/12/2007 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/25/2007 48 Male 214 lb 3/7/2007 Physician United States
Primary
Concomitant
Syncope Other Serious 12/31/2006 71 Male 3/13/2007 Physician United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/8/2007 56 Female 320 lb 3/28/2007 Consumer United States
Primary
Concomitant
Syncope Other Serious 12/31/2006 71 Male 4/2/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/25/2007 48 Male 214 lb 4/3/2007 Physician United States
Primary
Concomitant
Renal Disorder Hospitalization 2/16/2007 51 Female 4/27/2007 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/25/2007 48 Male 214 lb 4/25/2007 Physician United States
Primary
Concomitant
Visual Acuity Reduced 3/1/2006 80 Male 138 lb 2/22/2007 United States
Primary
Concomitant
Cerebral Haemorrhage Hospitalization 5/10/2007 63 Male 119 lb 6/1/2007 Physician Japan
Primary
Concomitant
Cerebral Haemorrhage Hospitalization 5/10/2007 63 Male 119 lb 6/8/2007 Physician Japan
Primary
Concomitant
Therapeutic Response Unexpected 1/1/2007 78 Female 5/17/2007 Other Health Professional United States
Primary
Concomitant
Hyperthyroidism Other Serious 1/1/2007 83 Female 6/20/2007 Other Health Professional France
Primary
Concomitant
Brain Stem Haemorrhage Hospitalization 5/10/2007 63 Male 119 lb 7/10/2007 Physician Japan
Primary
Concomitant
Tremor Other Serious 1/1/2006 71 Female 7/20/2007 Consumer United States
Primary
Secondary
Concomitant
Swelling Face Other Serious 6/1/2007 57 Male 7/30/2007 Pharmacist Canada
Primary
Concomitant
Myocardial Infarction Death 6/25/2007 Male 118 lb 8/1/2007 Other Health Professional United States
Primary
Concomitant
Swelling Face Other Serious 6/1/2007 57 Male 8/3/2007 Pharmacist Canada
Primary
Concomitant
Staphylococcal Infection Hospitalization 6/10/2007 52 Male 8/31/2007 Physician United States
Primary
Secondary
Concomitant
Muscle Spasticity Other Serious 1/1/2007 Female 177 lb 9/10/2007 United States
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 7/1/2006 66 Female 162 lb 9/12/2007 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Unexpected 1/1/2007 78 Female 8/16/2007 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 8/30/2006 60 Female 11/10/2007 Pharmacist United States
Primary
Concomitant
Arrhythmia Hospitalization 7/17/2007 77 Female 159 lb 11/29/2007 Greece
Primary
Concomitant
Weight Decreased 5/8/2007 76 Male 11/16/2007 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Death 6/25/2007 Male 118 lb 1/16/2008 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 12/11/2007 Female 1/24/2008 Physician United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Death 8/1/2002 68 Male 201 lb 2/1/2008 United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 12/11/2007 Female 3/21/2008 Physician United States
Primary
Secondary
Concomitant
Constipation Hospitalization 3/23/2008 70 Male 4/10/2008 Physician Sweden
Primary
Concomitant
Constipation Hospitalization 3/23/2008 70 Male 4/18/2008 Physician Sweden
Primary
Concomitant
Haemoglobin Decreased Hospitalization 3/23/2008 70 Male 5/20/2008 Physician Sweden
Primary
Concomitant
Constipation Hospitalization 3/23/2008 70 Male 5/23/2008 Physician Sweden
Primary
Concomitant
Skin Laceration Hospitalization 5/1/2008 76 Male 195 lb 5/20/2008 United States
Primary
Secondary
Concomitant
Constipation Hospitalization 3/1/2008 70 Male 7/21/2008 Physician Sweden
Primary
Concomitant
Sepsis Hospitalization 7/16/2008 70 Female 143 lb 7/31/2008 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 12/11/2007 73 Female 7/29/2008 Consumer France
Primary
Secondary
Concomitant
International Normalised Ratio Fluctuation 81 Female 172 lb 7/29/2008 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 12/21/2005 82 Female 7/28/2008 Physician Japan
Primary
Concomitant
No Adverse Event 65 Female 7/31/2008 Pharmacist United States
Primary
Concomitant
Pericarditis Hospitalization 7/29/2008 Female 8/14/2008 Pharmacist United States
Primary
Concomitant
Sepsis Hospitalization 7/16/2008 70 Female 143 lb 8/19/2008 Other Health Professional United States
Primary
Concomitant
Stevens-johnson Syndrome Life Threatening 8/1/2008 81 Male 8/25/2008 Italy
Primary
Secondary
Concomitant
Weight Increased Hospitalization 5/1/2008 76 Male 195 lb 9/3/2008 United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 9/17/2008 Lawyer United States
Primary
Concomitant
Stevens-johnson Syndrome Life Threatening 8/1/2008 81 Male 9/11/2008 Italy
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/16/2008 70 Female 143 lb 9/18/2008 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 5/1/2008 76 Male 195 lb 10/6/2008 United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/16/2008 70 Female 143 lb 11/4/2008 Other Health Professional United States
Primary
Concomitant
Drug Ineffective 6/4/2008 86 Female 11/13/2008 Consumer United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 1/1/2001 53 Female 211 lb 12/2/2008 Consumer United States
Primary
Concomitant
Syncope Other Serious 10/4/2008 56 Female 175 lb 11/29/2008 United States
Primary
Concomitant
Product Quality Issue Other Serious 11/1/2008 66 Female 165 lb 12/3/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 1/1/2008 69 Female 12/9/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Other Serious 1/1/2008 50 Female 155 lb 12/9/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 1/1/2008 70 Male 180 lb 12/9/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 9/1/2008 78 Female 225 lb 12/12/2008 Consumer United States
Primary
Concomitant
Hodgkin's Disease Hospitalization 9/23/2005 Male 144 lb 12/19/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/1/2008 89 Female 141 lb 12/18/2008 Consumer United States
Primary
Concomitant
Renal Function Test Abnormal Other Serious 10/5/2008 55 Male 12/19/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Other Serious 1/1/2007 57 Male 248 lb 12/22/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 5/1/2008 67 Male 254 lb 12/22/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 5/7/2008 71 Female 106 lb 12/22/2008 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 8/6/2008 84 Male 160 lb 12/23/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 9/1/2008 58 Female 12/23/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Other Serious 1/1/2007 86 Female 12/30/2008 Consumer United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 1/1/2001 53 Female 211 lb 1/14/2009 Consumer United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 53 Female 211 lb 1/28/2009 Other Health Professional United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 53 Female 211 lb 2/16/2009 Other Health Professional United States
Primary
Concomitant
Hypotension Other Serious 2/9/2008 76 Male 205 lb 2/20/2009 Lawyer United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 53 Female 211 lb 3/2/2009 Other Health Professional United States
Primary
Concomitant
Syncope Hospitalization 11/1/2008 40 Female 2/23/2009 Consumer United States
Primary
Concomitant
Hypotension Other Serious 2/9/2008 76 Male 205 lb 3/6/2009 Lawyer United States
Primary
Secondary
Concomitant
Ocular Toxicity 12/26/2005 73 Male 3/25/2009 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 6/1/2008 63 Male 3/12/2009 Consumer United States
Primary
Concomitant
Acute Myocardial Infarction Death 3/16/2007 74 Male 4/8/2009 Other Health Professional Greece
Primary
Secondary
Concomitant
Constipation Hospitalization 3/1/2008 Male 4/22/2009 Physician Sweden
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 2/9/2008 76 Male 205 lb 4/23/2009 Lawyer United States
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 2/9/2008 76 Male 205 lb 4/24/2009 Lawyer United States
Primary
Secondary
Concomitant

Drug Data