Isosorbide Mononitrate combined with Lantus

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tachycardia Death 11/17/2005 77 Female 1/3/2006 Other Health Professional Netherlands
Primary
Concomitant
Rectal Polyp Hospitalization 8/14/2005 64 Female 154 lb 12/30/2005 Physician United States
Primary
Concomitant
Pericarditis Other Serious 1/1/2005 Male 237 lb 1/11/2006 Physician United States
Primary
Secondary
Concomitant
Rectal Polyp Hospitalization 8/14/2005 64 Female 154 lb 1/20/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/23/2006 United States
Primary
Concomitant
Skin Discolouration Hospitalization 2/1/2004 42 Female 140 lb 12/27/2005 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 2/26/2006 64 Female 195 lb 4/13/2006 Physician United States
Primary
Secondary
Concomitant
Skin Burning Sensation Hospitalization 11/1/2005 77 Female 134 lb 5/3/2006 Physician United Kingdom
Primary
Concomitant
Skin Burning Sensation Hospitalization 11/1/2005 77 Female 134 lb 6/22/2006 Physician United Kingdom
Primary
Concomitant
Cardiac Failure Death 3/9/2006 Male 6/20/2006 Physician Netherlands
Primary
Concomitant
Macular Oedema 10/1/2005 74 Male 5/19/2006 Physician United States
Primary
Concomitant
Hypoglycaemia Hospitalization 7/5/2005 69 Male 5/8/2006 United States
Primary
Secondary
Concomitant
Syncope Hospitalization 5/1/2006 75 Male 7/25/2006 United States
Primary
Secondary
Concomitant
Pericarditis Other Serious 1/1/2005 Male 237 lb 8/25/2006 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Other Serious 5/29/2006 69 Male 195 lb 8/29/2006 Physician United States
Primary
Secondary
Concomitant
Tongue Oedema Other Serious 62 Male 9/28/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 3/9/2006 60 Male 9/27/2006 Netherlands
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 62 Male 224 lb 9/29/2006 Physician United States
Primary
Concomitant
Pancreatitis Other Serious 5/29/2006 69 Male 195 lb 10/5/2006 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Other Serious 5/29/2006 69 Male 195 lb 10/20/2006 Physician United States
Primary
Secondary
Concomitant
Tremor Other Serious 3/1/2006 66 Female 140 lb 11/16/2006 Physician United States
Primary
Concomitant
Injection Site Pain 5/1/2006 Female 12/20/2006 Pharmacist United States
Primary
Concomitant
Tremor 1/1/2006 78 Male 233 lb 10/19/2006 United States
Primary
Concomitant
Asthma Other Serious 1/21/2007 42 Male 1/31/2007 Consumer United Kingdom
Primary
Concomitant
Asthma Other Serious 1/21/2007 42 Male 2/2/2007 Consumer United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/25/2007 48 Male 214 lb 3/7/2007 Physician United States
Primary
Concomitant
Vision Blurred Hospitalization 12/1/2006 Male 155 lb 3/27/2007 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 1/21/2007 42 Male 4/9/2007 Physician United Kingdom
Primary
Concomitant
Vision Blurred Other Serious 73 Female 4/12/2007 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/25/2007 48 Male 214 lb 4/3/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/25/2007 48 Male 214 lb 4/25/2007 Physician United States
Primary
Concomitant
Vision Blurred Hospitalization 12/1/2006 Male 155 lb 5/14/2007 Consumer United States
Primary
Concomitant
Suicidal Ideation 10/27/2006 41 Male 2/28/2007 Other Health Professional United States
Primary
Concomitant
Urine Flow Decreased Other Serious 5/1/2006 59 Female 4/26/2007 United States
Primary
Concomitant
Hypoglycaemia Other Serious 12/4/2006 58 Male 201 lb 4/26/2007 Physician United States
Primary
Concomitant
Paraesthesia Oral Other Serious 6/15/2007 57 Female 250 lb 7/6/2007 Other Health Professional United Kingdom
Primary
Concomitant
Haemoptysis Other Serious 5/1/2007 Male 276 lb 7/25/2007 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 1/21/2007 42 Male 7/27/2007 Physician United Kingdom
Primary
Concomitant
Hypersensitivity Other Serious 62 Male 10/2/2007 United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/30/2006 60 Female 11/10/2007 Pharmacist United States
Primary
Concomitant
Wheezing Other Serious 1/1/2007 Male 254 lb 12/17/2007 Physician United Kingdom
Primary
Concomitant
International Normalised Ratio Decreased Other Serious 11/1/2007 Female 295 lb 1/29/2008 Physician United States
Primary
Concomitant
Interacting
Rash Hospitalization 3/6/2008 67 Male 5/14/2008 Physician Ireland
Primary
Concomitant
Ankle Fracture 4/4/2008 Female 185 lb 6/12/2008 United States
Primary
Concomitant
Vision Blurred 12/1/2007 78 Female 145 lb 6/19/2008 United States
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 6/16/2008 75 Male 8/6/2008 Other Health Professional Croatia (Local Name: Hrvatska)
Primary
Secondary
Concomitant
Jaundice Cholestatic Hospitalization 3/23/2008 47 Male 328 lb 8/13/2008 Pharmacist United States
Primary
Concomitant
Insomnia 5/1/2008 74 Female 5/21/2008 Other Health Professional United States
Primary
Concomitant
Syncope Other Serious 9/11/2008 Male 154 lb 9/17/2008 Physician Brazil
Primary
Concomitant
White Blood Cells Urine Positive Hospitalization 10/2/2008 Female 10/22/2008 Pharmacist United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 1/1/2001 53 Female 211 lb 12/2/2008 Consumer United States
Primary
Concomitant
Pleural Effusion Other Serious 10/2/2008 82 Female 12/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Chronic Life Threatening 5/13/2008 Female 241 lb 12/16/2008 Pharmacist United States
Primary
Concomitant
Wheezing Other Serious 5/1/2008 88 Female 191 lb 12/16/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 12/1/2008 72 Male 198 lb 12/22/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Other Serious 1/1/2007 57 Male 248 lb 12/22/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 1/1/2008 80 Male 12/22/2008 Consumer United States
Primary
Concomitant
Dyspnoea Other Serious 10/25/2008 75 Female 118 lb 12/29/2008 Physician United Kingdom
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 1/1/2001 53 Female 211 lb 1/14/2009 Consumer United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 4/1/2008 56 Female 1/15/2009 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 12/1/2008 72 Male 198 lb 1/21/2009 Consumer United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 53 Female 211 lb 1/28/2009 Other Health Professional United States
Primary
Concomitant
Diverticulitis Hospitalization 1/1/2009 Female 2/10/2009 Consumer United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 53 Female 211 lb 2/16/2009 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/31/2009 44 Female 117 lb 2/17/2009 Consumer Brazil
Primary
Secondary
Concomitant
Product Quality Issue Other Serious 10/25/2008 75 Female 118 lb 2/25/2009 Physician United Kingdom
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 53 Female 211 lb 3/2/2009 Other Health Professional United States
Primary
Concomitant
Ischaemic Hepatitis Other Serious 10/12/2008 82 Female 167 lb 2/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Hospitalization 3/3/2008 58 Male 3/30/2009 Consumer United States
Primary
Secondary
Concomitant
Product Quality Issue Other Serious 10/25/2008 75 Female 118 lb 4/29/2009 Other Health Professional United Kingdom
Primary
Concomitant
Percutaneous Coronary Intervention Hospitalization 3/23/2009 Male 6/2/2009 Consumer United States
Primary
Secondary
Concomitant
Percutaneous Coronary Intervention Hospitalization 3/23/2009 Male 6/9/2009 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 3/23/2009 Male 6/16/2009 Consumer United States
Primary
Secondary
Concomitant
Road Traffic Accident Other Serious 5/12/2009 Male 179 lb 6/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wrong Drug Administered Hospitalization 4/1/2009 Male 6/24/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 1/1/2007 Female 200 lb 6/29/2009 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 5/1/2009 Male 173 lb 7/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2008 55 Male 210 lb 7/9/2009 Consumer United States
Primary
Secondary
Concomitant
Hyperglycaemic Hyperosmolar Nonketotic Syndrome Other Serious 4/5/2004 60 Female 180 lb 7/22/2009 United States
Primary
Secondary
Concomitant
Road Traffic Accident Other Serious 5/1/2009 Male 173 lb 8/25/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Macular Degeneration Other Serious 1/1/2002 Female 8/21/2009 Physician United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 1/1/2001 53 Female 211 lb 9/21/2009 Other Health Professional United States
Primary
Concomitant
Tremor Other Serious 64 Female 9/21/2009 Consumer Brazil
Primary
Secondary
Concomitant
Head Injury Life Threatening 6/23/2009 Female 179 lb 6/23/2009 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2000 Male 290 lb 9/24/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2000 Male 290 lb 10/13/2009 Consumer United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 64 Male 11/18/2009 United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 64 Male 12/1/2009 Lawyer United States
Primary
Concomitant
Peritonitis Bacterial Other Serious 6/20/2009 Male 173 lb 11/3/2009 Other Health Professional United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 64 Male 1/8/2010 United States
Primary
Concomitant
Poor Quality Drug Administered Other Serious 1/1/2010 Male 1/22/2010 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 12/24/2006 61 Male 224 lb 1/20/2010 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 2/1/2007 74 Female 144 lb 1/20/2010 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 11/24/2009 64 Male 1/21/2010 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 1/1/1978 61 Male 224 lb 1/26/2010 Lawyer United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 6/10/2009 50 Male 2/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 8/10/2007 66 Female 2/10/2010 Other Health Professional United States
Primary
Concomitant
Vertigo Hospitalization 79 Male 142 lb 1/27/2010 Lawyer United States
Primary
Concomitant
Fluid Overload Hospitalization 1/15/2010 67 Female 2/5/2010 Consumer United States
Primary
Concomitant
Poor Quality Drug Administered Hospitalization 1/1/2010 Male 2/16/2010 Physician United States
Primary
Concomitant
Hypoglycaemic Unconsciousness Other Serious 1/1/2010 73 Female 3/2/2010 Consumer United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2007 58 Male 137 lb 3/4/2010 Lawyer United States
Primary
Concomitant
Vomiting Life Threatening 12/14/2007 69 Male 3/4/2010 Lawyer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/1/2007 74 Female 144 lb 3/3/2010 Lawyer United States
Primary
Concomitant
Death Death 2/1/2009 Female 3/18/2010 United States
Primary
Concomitant
Vomiting Hospitalization 1/23/2010 58 Male 266 lb 4/1/2010 Physician United Kingdom
Primary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2007 58 Male 137 lb 5/28/2010 Physician United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 5/7/2010 75 Male 6/2/2010 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 79 Male 142 lb 5/26/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 1/2/2007 69 Male 187 lb 6/7/2010 Lawyer United States
Primary
Secondary
Concomitant
Tongue Discolouration Hospitalization 5/3/2010 74 Female 121 lb 6/30/2010 Consumer United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 53 Female 211 lb 7/7/2010 Other Health Professional United States
Primary
Concomitant
Skin Discolouration Other Serious 1/1/2008 51 Male 247 lb 7/27/2010 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 8/1/2007 52 Male 176 lb 9/2/2010 Other Health Professional United States
Primary
Concomitant
Schizophrenia Other Serious 8/1/2010 52 Male 229 lb 9/15/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 5/25/2007 66 Female 9/21/2010 Other Health Professional United States
Primary
Concomitant
Skin Discolouration Other Serious 1/1/2008 51 Male 247 lb 9/22/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 9/29/2010 55 Female 10/5/2010 Other Health Professional Italy
Primary
Concomitant
Renal Failure Other Serious 6/26/2010 58 Female 176 lb 10/7/2010 Physician United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2007 58 Male 137 lb 10/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Schizophrenia Other Serious 1/1/2010 51 Male 242 lb 10/7/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 12/14/2007 69 Male 187 lb 10/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Upper-airway Cough Syndrome Female 10/13/2010 Consumer United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 9/29/2010 55 Female 10/15/2010 Other Health Professional Italy
Primary
Concomitant
Skin Exfoliation Life Threatening 9/1/2010 52 Male 10/19/2010 Physician China
Primary
Secondary
Pneumonia Life Threatening 9/1/2010 78 Male 194 lb 10/27/2010 Physician Australia
Primary
Secondary
Concomitant
Skin Exfoliation Life Threatening 9/1/2010 52 Male 10/28/2010 Physician China
Primary
Secondary
Nausea Other Serious 8/1/2007 52 Male 176 lb 10/28/2010 Other Health Professional United States
Primary
Concomitant
Pneumonia Life Threatening 9/1/2010 78 Male 194 lb 11/3/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 4/15/2010 55 Female 11/5/2010 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Life Threatening 9/28/2010 78 Male 194 lb 11/10/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 4/15/2010 55 Female 11/23/2010 Consumer United States
Primary
Concomitant
Fluid Overload Hospitalization 1/15/2010 67 Female 3/1/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 6/26/2010 58 Female 176 lb 12/16/2010 Physician United States
Primary
Concomitant
Malaise Hospitalization 8/1/2007 52 Male 176 lb 1/6/2011 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 12/14/2007 69 Male 187 lb 1/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrointestinal Perforation Hospitalization 7/14/2010 73 Male 249 lb 2/15/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cyanosis Death 2/1/2008 67 Male 192 lb 3/4/2011 Other Health Professional United States
Primary
Concomitant
Confusional State Other Serious 11/18/2008 63 Female 130 lb 3/18/2011 Physician United States
Primary
Concomitant
Agitation Hospitalization 2/1/2011 83 Male 3/28/2011 Consumer United States
Primary
Secondary
Concomitant
Hallucination Hospitalization 2/1/2011 83 Male 3/29/2011 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Death 10/1/2006 70 Male 290 lb 3/29/2011 Other Health Professional United States
Primary
Concomitant
Anxiety Death 10/1/2006 70 Male 290 lb 3/29/2011 Consumer United States
Primary
Concomitant
Periodontal Disease Other Serious 2/8/2005 65 Male 258 lb 4/13/2011 Physician United States
Primary
Secondary
Concomitant
Confusional State Other Serious 11/1/2007 58 Male 137 lb 4/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Haematochezia Hospitalization 2/1/2011 81 Male 4/20/2011 Consumer United States
Primary
Concomitant
Blood Pressure Increased Other Serious 12/1/2009 50 Male 175 lb 4/21/2011 Consumer United States
Primary
Concomitant
Cough Hospitalization 7/1/2010 75 Female 176 lb 4/27/2011 Physician United Kingdom
Primary
Concomitant
Death Other Serious 2/13/2008 69 Female 165 lb 5/12/2011 Physician United States
Primary
Concomitant
Cough Hospitalization 7/28/2009 75 Female 176 lb 5/20/2011 Consumer United Kingdom
Primary
Concomitant

Drug Data