Isosorbide Mononitrate combined with Lansoprazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Skin Ulcer Hospitalization 2/13/2002 Female 1/4/2006 France
Primary
Concomitant
Coronary Ostial Stenosis Hospitalization 11/21/2005 71 Male 192 lb 1/4/2006 United States
Primary
Secondary
Concomitant
Hepatitis Hospitalization 2/9/2005 69 Male 4/4/2005 Other Health Professional United States
Primary
Secondary
Concomitant
Extrasystoles Other Serious 12/1/2005 Male 1/20/2006 Physician Sweden
Primary
Concomitant
Unevaluable Event Hospitalization 11/1/2005 86 Female 1/17/2006 Other Health Professional Japan
Primary
Concomitant
Urticaria Required Intervention 6/28/2005 Male 168 lb Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 7/7/2005 82 Male 1/26/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonitis Death 6/1/2005 69 Male 1/30/2006 United Kingdom
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United States
Primary
Concomitant
Pneumonitis Death 6/1/2005 69 Male 2/6/2006 United Kingdom
Primary
Concomitant
Pain Other Serious 1/13/2006 44 Male 2/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Other Serious 5/15/2003 76 Female 77 lb 2/21/2006 Lawyer United Kingdom
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/23/2006 United States
Primary
Concomitant
Contusion Hospitalization 3/17/2004 53 Female 190 lb 12/27/2005 Consumer United States
Primary
Concomitant
Skin Discolouration Hospitalization 2/1/2004 42 Female 140 lb 12/27/2005 Consumer United States
Primary
Concomitant
Coronary Artery Occlusion Hospitalization 1/1/2003 67 Female 230 lb 12/27/2005 Other Health Professional United States
Primary
Concomitant
Troponin T Increased Hospitalization 3/2/2005 77 Male 134 lb 3/22/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Condition Aggravated Other Serious 1/1/2006 54 Male 269 lb 3/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pharyngeal Oedema Hospitalization 12/29/2005 66 Male 4/24/2006 Other Health Professional United Kingdom
Primary
Concomitant
Skin Burning Sensation Hospitalization 11/1/2005 77 Female 134 lb 5/3/2006 Physician United Kingdom
Primary
Concomitant
Ventricular Extrasystoles Other Serious 12/1/2005 Male 5/8/2006 Physician Sweden
Primary
Concomitant
Hyponatraemia Hospitalization 2/25/2005 78 Female 176 lb 5/25/2006 Physician Finland
Primary
Concomitant
Ventricular Hypertrophy Other Serious 12/1/2005 Male 6/6/2006 Physician Sweden
Primary
Concomitant
Chest Pain Hospitalization 10/31/2004 89 Female 6/8/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Skin Burning Sensation Hospitalization 11/1/2005 77 Female 134 lb 6/22/2006 Physician United Kingdom
Primary
Concomitant
Pruritus Other Serious 12/1/2001 78 Male 132 lb 6/28/2006 Physician United Kingdom
Primary
Concomitant
Hypertension Hospitalization 4/6/2006 66 Male 7/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Drug Hypersensitivity Hospitalization 4/6/2006 66 Male 7/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Subdural Haemorrhage Death 7/23/2004 Female 143 lb 8/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 6/12/2006 55 Female 8/9/2006 United States
Primary
Concomitant
Renal Failure Other Serious 3/3/2006 78 Male 141 lb 8/11/2006 Other Health Professional Japan
Primary
Concomitant
Ventricular Extrasystoles Other Serious 12/1/2005 Male 8/21/2006 Physician Sweden
Primary
Concomitant
Hypersensitivity Hospitalization 3/31/2006 66 Male 8/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Life Threatening 8/10/2006 60 Male 284 lb 9/1/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 8/10/2006 60 Male 271 lb 9/6/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Vasovagal Hospitalization 7/10/2005 63 Female 234 lb 9/15/2006 Other Health Professional United Kingdom
Primary
Concomitant
Steatorrhoea Life Threatening Male 230 lb 9/25/2006 Physician United Kingdom
Primary
Concomitant
Syncope Vasovagal Hospitalization 7/9/2005 63 Female 234 lb 10/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 12/1/2005 Male 10/12/2006 Physician Sweden
Primary
Concomitant
Vomiting Hospitalization 1/26/2005 76 Female 110 lb 10/18/2006 Physician Japan
Primary
Secondary
Concomitant
Musculoskeletal Disorder Other Serious 12/1/2005 Male 10/30/2006 Other Health Professional Sweden
Primary
Concomitant
Tibia Fracture Hospitalization 1/20/2006 56 Male 194 lb 11/9/2006 Physician United Kingdom
Primary
Concomitant
Breast Cancer Hospitalization 3/1/2006 Female 110 lb 11/18/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/26/2005 76 Female 110 lb 11/17/2006 Physician Japan
Primary
Secondary
Concomitant
Otorrhoea Hospitalization 7/9/2005 Female 234 lb 12/29/2006 Physician United Kingdom
Primary
Concomitant
Feeling Hot Other Serious 12/6/2006 81 Female 1/10/2007 United Kingdom
Primary
Concomitant
Orthostatic Hypotension Other Serious 81 Female 1/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
Delirium Hospitalization 10/22/2006 80 Male 1/27/2007 Physician Turkey
Primary
Concomitant
Otorrhoea Hospitalization 7/7/2005 Female 234 lb 2/2/2007 Physician United Kingdom
Primary
Concomitant
Myocardial Infarction Life Threatening 12/4/2006 59 Male 189 lb 2/16/2007 United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 12/4/2006 59 Male 189 lb 2/27/2007 United Kingdom
Primary
Secondary
Concomitant
Synovitis Other Serious 12/1/2005 Male 2/28/2007 Physician Sweden
Primary
Concomitant
Musculoskeletal Disorder Other Serious 12/1/2005 Male 2/28/2007 Physician Sweden
Primary
Concomitant
International Normalised Ratio Increased Other Serious 9/1/2006 46 Male 344 lb 3/27/2007 Physician United Kingdom
Primary
Concomitant
Myocardial Infarction Life Threatening 12/4/2006 59 Male 189 lb 3/29/2007 United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 12/4/2006 59 Male 189 lb 3/30/2007 United Kingdom
Primary
Secondary
Concomitant
Hypocoagulable State Hospitalization 9/29/2006 63 Female 75 lb 3/15/2007 Physician Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis Death 11/17/2006 Female 106 lb 4/12/2007 Other Health Professional United Kingdom
Primary
Concomitant
Oral Intake Reduced Other Serious 1/27/2007 Male 4/27/2007 Consumer United Kingdom
Primary
Concomitant
Oral Intake Reduced Other Serious 1/27/2007 Male 5/4/2007 United Kingdom
Primary
Concomitant
Renal Impairment Other Serious 1/27/2007 Male 5/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Infective Exacerbation Of Chronic Obstructive Airways Disease Hospitalization 11/1/2006 Female 146 lb 5/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Life Threatening 64 Male 207 lb 6/5/2007 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Life Threatening 1/1/2006 64 Male 5/31/2007 United Kingdom
Primary
Concomitant
Hypoaesthesia Other Serious 10/6/2006 Male 181 lb 7/16/2007 Consumer United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 80 Female 7/26/2007 Physician United Kingdom
Primary
Concomitant
Hypoaesthesia Other Serious 10/6/2006 Male 181 lb 7/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Synovitis Other Serious 12/1/2005 Male 8/13/2007 Physician Sweden
Primary
Concomitant
Rhabdomyolysis Hospitalization 7/13/2007 80 Female 8/14/2007 Physician United Kingdom
Primary
Concomitant
Mouth Ulceration Disability 5/8/2007 89 Female 9/10/2007 Other Health Professional United Kingdom
Primary
Concomitant
Incorrect Dose Administered Other Serious 7/30/2007 76 Female 88 lb 10/16/2007 Physician Japan
Primary
Secondary
Concomitant
Cholecystitis Acute Death 7/1/2007 75 Female 108 lb 11/5/2007 Physician Japan
Primary
Concomitant
Nausea Other Serious 2/27/2007 62 Male 11/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Application Site Dermatitis Other Serious 10/12/2007 87 Female 11/29/2007 Physician United Kingdom
Primary
Concomitant
Chest Pain Other Serious 9/15/2007 Female 73 lb 1/22/2008 United Kingdom
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2005 1/23/2008 Other Health Professional United Kingdom
Primary
Concomitant
Myoclonus Death 10/1/2007 92 Female 2/11/2008 Other Health Professional Spain
Primary
Concomitant
Tremor Hospitalization 1/1/2007 81 Male 2/12/2008 Other Health Professional France
Primary
Concomitant
Rhabdomyolysis Hospitalization 1/1/2007 79 Male 2/13/2008 Other Health Professional Israel
Primary
Concomitant
Sinus Congestion 1/17/2008 Female 3/15/2008 United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2005 3/24/2008 Other Health Professional United Kingdom
Primary
Concomitant
Mental Status Changes Required Intervention 2/17/2008 80 Female 141 lb 2/18/2008 Pharmacist United States
Primary
Secondary
Concomitant
Constipation Hospitalization 3/23/2008 70 Male 4/10/2008 Physician Sweden
Primary
Concomitant
Constipation Hospitalization 3/23/2008 70 Male 4/18/2008 Physician Sweden
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 4/18/2008 United States
Primary
Concomitant
Myocardial Ischaemia Life Threatening 8/30/2005 Male 139 lb 4/22/2008 United States
Primary
Concomitant
Pancreatitis Hospitalization 4/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 4/30/2008 United States
Primary
Concomitant
Pancreatitis Hospitalization 82 Female 5/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 82 Female 5/2/2008 United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 82 Female 5/2/2008 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 3/31/2008 80 Male 4/17/2008 United Kingdom
Primary
Concomitant
Pancreatitis Other Serious 82 Female 5/6/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 5/9/2008 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 5/15/2008 United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization 3/23/2008 70 Male 5/20/2008 Physician Sweden
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 88 Male 5/21/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 5/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Constipation Hospitalization 3/23/2008 70 Male 5/23/2008 Physician Sweden
Primary
Concomitant
Myocardial Ischaemia Hospitalization 3/6/2008 80 Male 5/20/2008 United Kingdom
Primary
Concomitant
Rash Hospitalization 3/6/2008 67 Male 5/14/2008 Physician Ireland
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 88 Male 5/27/2008 Other Health Professional France
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 88 Male 5/22/2008 United Kingdom
Primary
Secondary
Concomitant
Left Ventricular Dysfunction Hospitalization 1/1/2004 80 Male 5/23/2008 United Kingdom
Primary
Concomitant
Cardiac Failure Congestive Other Serious 9/5/2007 81 Male 6/11/2008 Japan
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 88 Male 6/9/2008
Primary
Secondary
Concomitant
Vomiting Other Serious 3/2/2008 Female 242 lb 6/18/2008 Physician United Kingdom
Primary
Concomitant
Suicide Attempt Other Serious 1/1/2005 Male 6/17/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Cardiomegaly Other Serious 9/11/2007 81 Male 6/27/2008 Japan
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 8/30/2005 Male 139 lb 6/27/2008 United States
Primary
Concomitant
Cardiomegaly Other Serious 9/11/2007 81 Male 7/17/2008 Japan
Primary
Secondary
Concomitant
Constipation Hospitalization 3/1/2008 70 Male 7/21/2008 Physician Sweden
Primary
Concomitant
Myocardial Infarction Hospitalization 12/21/2005 82 Female 7/28/2008 Physician Japan
Primary
Concomitant
Cardiomegaly Other Serious 9/11/2007 81 Male 8/6/2008 Japan
Primary
Secondary
Concomitant
Pain Hospitalization 7/2/2008 59 Male 8/8/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Tremor Hospitalization 1/1/2007 81 Male 9/23/2008 Other Health Professional France
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2005 61 Male 10/16/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Life Threatening 7/1/2008 Male 245 lb 10/18/2008 Physician United Kingdom
Primary
Concomitant
Hypertriglyceridaemia Other Serious 10/6/2008 70 Male 10/30/2008 Physician Japan
Primary
Concomitant
Hypertriglyceridaemia Other Serious 10/6/2008 70 Male 11/4/2008 Physician Japan
Primary
Concomitant
Hypertriglyceridaemia 10/6/2008 70 Male 11/11/2008 Physician Japan
Primary
Concomitant
Syncope Other Serious 10/22/2008 71 Male 11/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 10/22/2008 71 Male 11/17/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 10/22/2008 71 Male 11/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 10/22/2008 71 Male 11/26/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pain Hospitalization 7/2/2008 59 Male 12/1/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Syncope 10/22/2008 71 Male 12/9/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haemoglobin Decreased 9/1/2008 Female 250 lb 12/12/2008 United States
Primary
Secondary
Concomitant
Troponin Increased Other Serious 1/1/2003 78 Male 140 lb 1/8/2009 United States
Primary
Concomitant
Throat Tightness Other Serious 12/5/2008 59 Female 179 lb 1/8/2009 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Fungal Hospitalization 6/14/2008 88 Female 1/13/2009 Consumer Portugal
Primary
Concomitant
Myocardial Infarction Other Serious 10/1/2008 Male 152 lb 1/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Other Serious Male 152 lb 2/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Unevaluable Event Hospitalization 9/1/2004 Female 179 lb 2/13/2009 Physician United Kingdom
Primary
Concomitant
Speech Disorder Hospitalization 86 Female 2/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Serratia Infection Hospitalization 9/1/2004 Female 179 lb 2/23/2009 Physician United Kingdom
Primary
Concomitant
Tardive Dyskinesia Other Serious 86 Female 2/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Speech Disorder Hospitalization 86 Female 2/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tardive Dyskinesia Other Serious 86 Female 2/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Tardive Dyskinesia Disability 1/23/2009 86 Female 2/20/2009 United Kingdom
Primary
Concomitant
Speech Disorder Hospitalization 86 Female 3/2/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Swollen Tongue Life Threatening 1/4/2009 88 Female 3/3/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Other Serious 1/30/2009 86 Female 3/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Other Serious 1/30/2009 86 Female 3/18/2009 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 1/30/2009 86 Female 3/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 1/30/2009 86 Female 3/22/2009 United Kingdom
Primary
Secondary
Concomitant
Troponin Increased Other Serious 1/1/2003 78 Male 140 lb 4/14/2009 United States
Primary
Concomitant
Constipation Hospitalization 3/1/2008 Male 4/22/2009 Physician Sweden
Primary
Secondary
Concomitant
Nephropathy Other Serious 66 Male 4/23/2009 Physician United Kingdom
Primary
Concomitant

Drug Data