Isosorbide combined with Metoprolol Tartrate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Nephrolithiasis Other Serious 1/1/2000 49 Male 205 lb 2/21/2006 Lawyer United States
Primary
Concomitant
Vertigo Other Serious 1/1/2000 78 Male 198 lb 2/23/2006 Physician United States
Primary
Concomitant
Nephrolithiasis Other Serious 1/1/2000 49 Male 205 lb 2/28/2006 Physician United States
Primary
Concomitant
Blood Glucose Increased Other Serious 7/1/2005 80 Female 160 lb 3/2/2006 United States
Primary
Concomitant
Vision Blurred Hospitalization 4/29/2006 84 Male 172 lb 5/9/2006 Pharmacist United States
Primary
Secondary
Concomitant
Syncope Hospitalization 5/2/2006 80 Male 222 lb 5/11/2006 Pharmacist United States
Primary
Secondary
Hypotension Hospitalization 2/23/2006 85 Male Pharmacist United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 56 Male 290 lb 6/2/2006 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Hospitalization 7/1/2004 47 Male 6/6/2006 Consumer United States
Primary
Concomitant
Urine Amphetamine Positive 2/9/2006 79 Male 5/5/2006 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 4/25/2006 Male 203 lb 4/26/2006 Pharmacist United States
Primary
Concomitant
Visual Disturbance Hospitalization 9/10/2006 80 Male 212 lb 9/21/2006 Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Disorder Life Threatening 4/20/2005 85 Male 150 lb 9/22/2006 Pharmacist United States
Primary
Concomitant
Hypoglycaemia Hospitalization 8/3/2006 64 Male Pharmacist United States
Primary
Concomitant
Hypoglycaemia Hospitalization 7/26/2006 79 Male Pharmacist United States
Primary
Concomitant
Clostridial Infection Hospitalization 10/5/2006 57 Male 164 lb 10/12/2006 Pharmacist United States
Primary
Concomitant
Respiratory Tract Infection Hospitalization 9/17/2006 48 Female 11/7/2006 Consumer United States
Primary
Concomitant
Tinnitus 11/13/2006 Consumer United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 3/1/2006 Female 160 lb 11/16/2006 Consumer United States
Primary
Concomitant
Respiratory Arrest Other Serious 1/26/2007 37 Female 302 lb 2/1/2007 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/26/2007 37 Female 302 lb 2/14/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious 10/1/2007 Male 8/18/2008 Consumer United States
Primary
Concomitant
Pain Other Serious 1/1/2006 Male 241 lb 8/26/2008 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 10/1/2007 54 Male 190 lb 8/28/2008 Consumer United States
Primary
Concomitant
Pruritus 6/25/2008 Male 8/29/2008 United States
Primary
Concomitant
Supraventricular Tachycardia Other Serious 7/10/2008 71 Male 201 lb 9/4/2008 Consumer United States
Primary
Concomitant
Diarrhoea Other Serious 4/3/2008 65 Female 134 lb 9/19/2008 Consumer United States
Primary
Concomitant
Hot Flush Other Serious 6/18/2008 83 Male 161 lb 9/22/2008 Pharmacist United States
Primary
Concomitant
Feeling Drunk Male 9/24/2008 Consumer United States
Primary
Concomitant
Drug Hypersensitivity Hospitalization 8/1/2008 88 Male 9/25/2008 Pharmacist United States
Primary
Concomitant
Osteoarthritis 62 Female 228 lb 10/7/2008 Consumer United States
Primary
Concomitant
Oropharyngeal Pain 10/29/2007 86 Female 10/7/2008 Consumer United States
Primary
Concomitant
Fluid Retention Hospitalization 7/28/2008 Female 10/7/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2008 Male 174 lb 9/30/2008 Consumer United States
Primary
Concomitant
Renal Failure Death 83 Male 10/21/2008 United States
Primary
Concomitant
Fluid Retention Hospitalization 7/28/2008 Female 10/30/2008 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 69 Female 159 lb 11/11/2008 Consumer United States
Primary
Concomitant
Chest Discomfort Hospitalization 1/27/2008 Female 11/11/2008 Consumer
Primary
Concomitant
Hospitalisation Hospitalization 1/1/2006 Male 155 lb 11/17/2008 Consumer United States
Primary
Concomitant
Pain Other Serious 1/1/2006 Male 241 lb 11/17/2008 Consumer United States
Primary
Concomitant
Lethargy Required Intervention 9/2/2008 77 Male 165 lb 10/15/2008 Pharmacist United States
Primary
Concomitant
Pain In Extremity 9/1/2008 78 Male 11/14/2008 United States
Primary
Concomitant
Skin Burning Sensation 7/22/2008 Female 11/26/2008 United States
Primary
Concomitant
Paraesthesia 9/5/2008 Male 11/26/2008 United States
Primary
Concomitant
Paraesthesia Female 11/26/2008 United States
Primary
Secondary
Concomitant
Headache 10/1/2008 Male 11/26/2008 United States
Primary
Concomitant
Hospitalisation Hospitalization 1/27/2008 Female 12/5/2008 Consumer
Primary
Concomitant
Myocardial Infarction Hospitalization 55 Male 226 lb 12/8/2008 Lawyer United States
Primary
Concomitant
Vomiting Death 12/4/2008 Male 191 lb 12/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Lip Swelling 93 Female 117 lb 12/17/2008 United States
Primary
Concomitant
Diverticulitis 5/1/2008 65 Male 185 lb 12/17/2008 United States
Primary
Concomitant
Vomiting 1/1/2008 58 Female 140 lb 12/17/2008 Consumer United States
Primary
Concomitant
Hyperkalaemia Hospitalization 75 Female 12/18/2008 Other Health Professional Poland
Primary
Secondary
Frequent Bowel Movements 9/2/2008 64 Male 12/10/2008 Consumer United States
Primary
Concomitant
Intermittent Claudication 9/1/2008 78 Male 171 lb 2/16/2009 Physician United States
Primary
Concomitant
Vision Blurred Hospitalization 84 Female 2/25/2009 United States
Primary
Concomitant
Migraine With Aura Other Serious 1/1/2004 Female 250 lb 3/6/2009 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 55 Male 226 lb 3/20/2009 Other Health Professional United States
Primary
Concomitant
Tendon Disorder Other Serious 1/1/2005 72 Female 139 lb 3/26/2009 Physician United States
Primary
Concomitant
Varicose Vein Ruptured Hospitalization 1/1/2007 Female 4/13/2009 Consumer
Primary
Concomitant
Abdominal Discomfort Male 5/4/2009 Physician United States
Primary
Concomitant
Pyrexia 9/26/2007 5/4/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 5/21/2009 Female 136 lb 6/15/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 5/21/2009 Female 136 lb 6/24/2009 Other Health Professional United States
Primary
Concomitant
Unevaluable Event Death 67 Male 6/30/2009 Lawyer United States
Primary
Concomitant
Social Problem Hospitalization 1/20/2006 73 Male 163 lb 8/4/2009 Other Health Professional United States
Primary
Concomitant
Venous Insufficiency Other Serious 3/13/2006 8/17/2009 Consumer United States
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 1/20/2006 73 Male 163 lb 8/14/2009 United States
Primary
Concomitant
Weight Decreased Death 73 Female 8/28/2009 United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 68 Female 160 lb 8/31/2009 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/1/2007 48 Male 456 lb 9/1/2009 United States
Primary
Concomitant
Vision Blurred Hospitalization 59 Female 8/31/2009 United States
Primary
Concomitant
Unevaluable Event Death 68 Male 9/1/2009 Lawyer United States
Primary
Concomitant
Social Problem Hospitalization 1/20/2006 73 Male 163 lb 9/2/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 7/1/2007 48 Male 456 lb 9/4/2009 United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 11/23/2007 66 Male 802 lb 9/3/2009 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 9/3/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 76 Male 9/4/2009 Lawyer United States
Primary
Concomitant
Unevaluable Event Hospitalization 1/20/2006 73 Male 163 lb 9/8/2009 United States
Primary
Concomitant
Ureteric Cancer Hospitalization 66 Male 9/8/2009 United States
Primary
Concomitant
Tinnitus 6/30/2009 Male 168 lb 9/17/2009 Physician
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2002 70 Female 9/21/2009 Consumer United States
Primary
Concomitant
Diabetic Coma Other Serious 8/30/2003 33 Female 113 lb 9/23/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 10/16/2009 Lawyer United States
Primary
Concomitant
Wheezing Hospitalization 66 Male 10/17/2009 United States
Primary
Concomitant
Vomiting Hospitalization 2/20/2008 65 Female 10/26/2009 United States
Primary
Concomitant
Wheezing Other Serious 9/3/2009 59 Female 386 lb 11/3/2009 Consumer United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 9/7/2008 53 Male 243 lb 10/27/2009 United States
Primary
Concomitant
Paralysis Hospitalization 10/27/2009 84 Male 212 lb 11/9/2009 United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 78 Female 11/4/2009 United States
Primary
Concomitant
Flushing Male 11/25/2009 United States
Primary
Concomitant
Pruritus Male 250 lb 11/25/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/27/2009 67 Male 214 lb 12/4/2009 Other Health Professional United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 78 Female 12/1/2009 Lawyer United States
Primary
Concomitant
Wound Secretion Hospitalization Male 12/1/2009 Lawyer United States
Primary
Concomitant
Local Swelling Male 12/9/2009 Consumer United States
Primary
Concomitant
Hypotension Hospitalization 9/1/2009 Female 12/15/2009 Consumer United States
Primary
Concomitant
Venous Insufficiency Other Serious 3/13/2006 12/17/2009 Consumer United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 2/28/2009 78 Male 12/17/2009 United States
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 79 Male 12/11/2009 United States
Primary
Concomitant
Vomiting Hospitalization 79 Male 12/10/2009 United States
Primary
Concomitant
Somnolence 1/1/2009 74 Male 190 lb 12/22/2009 Consumer United States
Primary
Concomitant
Peripheral Coldness 1/1/2009 76 Male 217 lb 12/22/2009 Consumer United States
Primary
Concomitant
Muscle Spasms 1/1/2009 68 Male 140 lb 12/22/2009 Physician United States
Primary
Concomitant
Musculoskeletal Discomfort Hospitalization 11/17/2009 Female 110 lb 12/28/2009 United States
Primary
Concomitant
Ventricular Fibrillation Other Serious 6/26/2009 72 Male 139 lb 12/28/2009 United States
Primary
Concomitant
Myocardial Infarction Death 74 Male 12/23/2009 Lawyer United States
Primary
Concomitant
Occult Blood Positive Other Serious 12/22/2009 73 Female 1/4/2010 Consumer United States
Primary
Secondary
Concomitant
Venous Occlusion Other Serious 12/1/2008 Male 180 lb 1/12/2010 Consumer United States
Primary
Concomitant
Dyspnoea Death 84 Male 139 lb 1/26/2010 Consumer United States
Primary
Concomitant
Multiple Injuries Death Male 1/15/2010 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 64 Female 1/20/2010 United States
Primary
Concomitant
Vomiting Hospitalization 79 Male 1/21/2010 United States
Primary
Concomitant
Ageusia 1/7/2010 90 Female 190 lb 1/26/2010 United States
Primary
Concomitant
Weight Increased Hospitalization 11/1/2009 87 Male 2/2/2010 Consumer United States
Primary
Concomitant
Wound Infection Hospitalization 73 Male 1/22/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 79 Male 1/23/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 78 Female 1/22/2010 United States
Primary
Concomitant
Product Quality Issue Other Serious 72 Female 189 lb 2/15/2010 Consumer United States
Primary
Concomitant
Occult Blood Positive Other Serious 12/22/2009 73 Female 178 lb 2/16/2010 Physician United States
Primary
Secondary
Concomitant
Flushing 10/25/2009 Male 205 lb 2/16/2010 United States
Primary
Concomitant
Hepatic Failure Hospitalization Female 2/18/2010 Consumer United States
Primary
Concomitant
Post Procedural Myocardial Infarction Hospitalization 6/18/2009 65 Female 2/4/2010 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 1/17/2010 84 Male 139 lb 2/22/2010 Physician United States
Primary
Concomitant
Weight Increased Hospitalization Male 2/5/2010 Lawyer United States
Primary
Concomitant
Ageusia Other Serious 1/7/2010 50 Male 150 lb 2/22/2010 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 81 Female 2/19/2010 United States
Primary
Concomitant
Tremor Hospitalization 2/1/2010 Male 278 lb 3/4/2010 Consumer United States
Primary
Concomitant
Thoracic Vertebral Fracture Hospitalization 65 Female 160 lb 2/22/2010 United States
Primary
Concomitant
Product Quality Issue Other Serious 12/22/2009 73 Female 178 lb 3/16/2010 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious Female 148 lb 3/16/2010 Physician United States
Primary
Concomitant
Pain In Extremity Other Serious Female 4/29/2010 Consumer United States
Primary
Secondary
Colitis Ischaemic Hospitalization 4/1/2010 81 Female 127 lb 5/7/2010 Physician United States
Primary
Concomitant
Poisoning Other Serious 60 Female 4/30/2010 Consumer United States
Primary
Secondary
Post Procedural Infection Hospitalization 4/1/2010 79 Male 199 lb 5/17/2010 Consumer United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization Female 158 lb 5/17/2010 Physician United States
Primary
Concomitant
Fatigue 5/1/2010 50 Female 5/17/2010 United States
Primary
Concomitant
Nausea Other Serious 1/21/2010 71 Male 224 lb 5/19/2010 United States
Primary
Concomitant
Ventricular Fibrillation Other Serious 62 Male 5/25/2010 United States
Primary
Concomitant
Skin Tightness Other Serious 1/1/2004 59 Female 269 lb 6/7/2010 Lawyer United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 11/29/2007 49 Male 190 lb 6/8/2010 United States
Primary
Concomitant
Skin Tightness Other Serious 1/1/2004 59 Female 269 lb 6/10/2010 Lawyer United States
Primary
Secondary
Concomitant
Tremor Hospitalization 2/1/2010 54 Male 278 lb 6/11/2010 Physician United States
Primary
Concomitant
Somnolence Other Serious Female 6/21/2010 Consumer United States
Primary
Concomitant
Skin Tightness Other Serious 1/1/2004 59 Female 269 lb 6/23/2010 Lawyer United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 9/1/2006 79 Male 152 lb 7/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Rhinorrhoea Other Serious 2/29/2008 87 Female 105 lb 7/29/2010 Other Health Professional United States
Primary
Concomitant
Tinnitus 6/1/2008 84 Female 110 lb 7/29/2010 Consumer United States
Primary
Concomitant
Pruritus 1/1/2006 52 Male 205 lb 7/31/2010 Consumer United States
Primary
Secondary
Concomitant
Neuropathy Peripheral 1/2/2002 77 Male 196 lb 7/31/2010 Consumer United States
Primary
Secondary
Concomitant

Drug Data