Isosorbide combined with Metformin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Urine Analysis Abnormal Other Serious 10/30/2005 Female 194 lb 1/4/2006 United States
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 3/4/2003 66 Female 238 lb 1/17/2006 Physician United States
Primary
Concomitant
Respiratory Disorder Hospitalization 7/4/2004 64 Female 205 lb 2/13/2006 Lawyer United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2004 79 Female 115 lb 2/21/2006 Lawyer United States
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 3/4/2003 66 Female 238 lb 2/21/2006 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 2/28/2006 86 Female 3/2/2006 Consumer United States
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 3/4/2003 66 Female 238 lb 3/22/2006 Physician United States
Primary
Concomitant
Pneumonia Other Serious 1/1/1999 58 Female 170 lb 3/16/2006 United States
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 3/4/2003 66 Female 238 lb 3/29/2006 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2006 51 Male 278 lb 3/21/2006 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 2/28/2006 86 Female 3/30/2006 Consumer United States
Primary
Concomitant
Tooth Disorder Other Serious 3/1/2006 Female 180 lb 4/6/2006 Consumer United States
Primary
Secondary
Concomitant
Ventricular Hypokinesia Hospitalization 7/30/2003 66 Female 238 lb 4/13/2006 Physician United States
Primary
Concomitant
Respiratory Disorder Other Serious 75 Female 180 lb 4/7/2006 United States
Primary
Secondary
Concomitant
Vascular Occlusion Hospitalization 2/1/2004 63 Male 243 lb 4/28/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2003 84 Female 141 lb 5/1/2006 Lawyer United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2004 79 Female 115 lb 5/1/2006 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 11/3/2001 64 Male 181 lb 5/3/2006 Physician United States
Primary
Secondary
Concomitant
Wound Infection Hospitalization 12/20/2000 58 Female 192 lb 5/8/2006 Physician United States
Primary
Concomitant
Spinal Cord Disorder Other Serious 1/1/2001 58 Male 209 lb 5/16/2006 Physician United States
Primary
Concomitant
High Density Lipoprotein Decreased Other Serious 3/1/2006 Female 180 lb 7/10/2006 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/1/2001 62 Female 8/22/2006 Consumer United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 3/1/2006 Female 160 lb 11/16/2006 Consumer United States
Primary
Concomitant
Skin Cancer Other Serious 3/1/2006 Female 12/8/2006 Physician United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 2/26/2006 Female 12/8/2006 Physician United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 2/13/2007 48 Female 337 lb 5/3/2007 Other Health Professional United States
Primary
Concomitant
Hyperhidrosis Hospitalization 4/27/2008 49 Male 280 lb 8/7/2008 United States
Primary
Concomitant
Overdose Other Serious Male 8/22/2008 United States
Primary
Interacting
Loss Of Consciousness Other Serious 9/29/2008 Male 267 lb 10/16/2008 Consumer United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 84 Male 10/28/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 9/29/2008 84 Male 159 lb 1/26/2009 Physician United States
Primary
Concomitant
Visual Impairment Death 11/12/2008 Male 200 lb 2/11/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/29/2008 84 Male 159 lb 2/23/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 5/21/2009 Female 136 lb 6/24/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 3/18/2009 56 Female 258 lb 7/17/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 76 Male 7/22/2009 Lawyer United States
Primary
Concomitant
Vision Blurred Hospitalization 59 Female 7/22/2009 Lawyer United States
Primary
Concomitant
Unevaluable Event Hospitalization 7/1/2007 48 Male 7/28/2009 Consumer United States
Primary
Concomitant
Vomiting Other Serious 3/18/2008 56 Female 258 lb 7/22/2009 United States
Primary
Concomitant
Thirst Other Serious 6/2/2009 Female 140 lb 8/11/2009 Other Health Professional United States
Primary
Concomitant
Social Problem Hospitalization 1/20/2006 73 Male 163 lb 8/4/2009 Other Health Professional United States
Primary
Concomitant
Renal Disorder Death 67 Male 8/3/2009 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 3/18/2008 56 Female 258 lb 8/6/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2005 Male 242 lb 8/12/2009 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 9/17/2009 Consumer United States
Primary
Concomitant
Platelet Count Decreased Other Serious 1/1/2009 Female 185 lb 10/7/2009 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 10/10/2009 United States
Primary
Concomitant
Renal Failure Acute Other Serious 12/8/2007 71 Female 10/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/20/2008 65 Female 10/22/2009 United States
Primary
Concomitant
Renal Failure Hospitalization 8/1/2009 Male 1/4/2010 Physician United States
Primary
Concomitant
Drug Hypersensitivity Other Serious 3/1/2008 56 Female 157 lb 1/4/2010 Lawyer United States
Primary
Concomitant
Coronary Artery Occlusion Other Serious 1/1/2009 Female 155 lb 1/7/2010 Consumer Brazil
Primary
Secondary
Concomitant
Drug Hypersensitivity Other Serious 3/1/2008 56 Female 157 lb 1/21/2010 Lawyer United States
Primary
Concomitant
Renal Failure Other Serious 8/1/2009 Male 1/28/2010 Physician United States
Primary
Concomitant
Muscle Spasms Female 175 lb 1/30/2010 Consumer United States
Primary
Concomitant
Chromaturia Other Serious 80 Female 2/21/2010 Physician United States
Primary
Concomitant
Cystoscopy Other Serious 80 Female 3/18/2010 Physician United States
Primary
Concomitant
Procedural Pain Other Serious 10/1/2009 60 Female 4/21/2010 United States
Primary
Secondary
Pain In Extremity Other Serious 60 Female 4/28/2010 Consumer United States
Primary
Secondary
Pain In Extremity Other Serious Female 4/29/2010 Consumer United States
Primary
Secondary
Cystoscopy Other Serious 80 Female 5/4/2010 Physician United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 3/26/2010 76 Male 143 lb 5/31/2010 Physician Mexico
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 11/29/2007 49 Male 190 lb 6/8/2010 United States
Primary
Concomitant
Dyspnoea Other Serious 1/1/2009 65 Female 6/7/2010 Consumer United States
Primary
Concomitant
Pruritus Female 203 lb 6/16/2010 United States
Primary
Concomitant
Drug Interaction 1/1/2007 60 Male 230 lb 7/13/2010 Consumer United States
Primary
Concomitant
Interacting
Insomnia 4/24/2008 64 Male 230 lb 7/21/2010 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 1/1/2010 82 Female 8/27/2010 Physician United States
Primary
Concomitant
Sunburn 8/1/2008 62 Male 8/27/2010 United States
Primary
Concomitant
Paraesthesia 8/1/2009 62 Male 214 lb 8/27/2010 United States
Primary
Concomitant
Skin Burning Sensation Male 186 lb 8/27/2010 United States
Primary
Concomitant
Sensory Disturbance 1/1/1999 61 Male 190 lb 8/28/2010 United States
Primary
Concomitant
Flushing 12/17/2009 68 Female 8/28/2010 United States
Primary
Concomitant
Blood Glucose Decreased 2/4/2010 67 Male 268 lb 8/28/2010 United States
Primary
Concomitant
Urticaria 11/1/2009 68 Male 8/28/2010 United States
Primary
Concomitant
Flushing 3/1/2010 61 Female 179 lb 8/29/2010 United States
Primary
Concomitant
Insomnia 5/19/2010 71 Male 175 lb 8/29/2010 Consumer United States
Primary
Concomitant
Generalised Erythema 5/24/2010 46 Female 203 lb 8/29/2010 Consumer United States
Primary
Concomitant
Abnormal Dreams Male 8/29/2010 Consumer United States
Primary
Concomitant
Encephalopathy Hospitalization 7/7/2008 76 Female 286 lb 8/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Supraventricular Extrasystoles Other Serious 8/3/2006 73 Male 9/1/2010 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 67 Male 220 lb 9/9/2010 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Death 7/15/2010 59 Male 202 lb 8/30/2010 Physician United States
Primary
Concomitant
Pharyngeal Oedema Other Serious 3/1/2008 50 Male 328 lb 9/15/2010 Physician United States
Primary
Concomitant
Pancreatitis Acute Other Serious 7/10/2010 58 Female 236 lb 9/23/2010 Physician United States
Primary
Concomitant
Oropharyngeal Pain 8/12/2010 80 Female 9/23/2010 Consumer
Primary
Concomitant
Death Other Serious 5/25/2010 76 Female 241 lb 10/1/2010 Other Health Professional United States
Primary
Concomitant
Myalgia 9/1/2010 86 Male 210 lb 10/13/2010 Consumer United States
Primary
Secondary
Concomitant
Myalgia 9/1/2010 86 Male 210 lb 10/22/2010 Consumer United States
Primary
Secondary
Concomitant
Sinus Disorder 12/1/2010 80 Male 165 lb 12/24/2010 Consumer United States
Primary
Concomitant
Headache Hospitalization 1/1/2010 83 Female 1/6/2011 Other Health Professional United States
Primary
Concomitant
Chest Discomfort Hospitalization 76 Male 3/2/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting 5/26/2011 58 Female 191 lb 5/30/2011 Consumer United States
Primary
Concomitant
Oscillopsia 6/9/2011 77 Female 6/16/2011 Consumer United States
Primary
Concomitant
Disturbance In Attention Hospitalization 4/1/2011 Male 6/24/2011 Consumer United Kingdom
Primary
Concomitant
Amnesia Hospitalization 4/1/2011 Male 7/26/2011 Physician United Kingdom
Primary
Concomitant
Vision Blurred 6/9/2011 77 Female 7/25/2011 Consumer United States
Primary
Concomitant
Disturbance In Attention Hospitalization 4/1/2011 53 Male 205 lb 8/23/2011 Physician United Kingdom
Primary
Concomitant
Hyperhidrosis Hospitalization 4/1/2011 53 Male 205 lb 8/29/2011 Physician United Kingdom
Primary
Concomitant
Pollakiuria 2/6/2012 72 Female 146 lb 3/1/2012 Physician United States
Primary
Concomitant
Sensation Of Pressure Other Serious Female 156 lb 3/22/2013 Consumer Us
Primary
Concomitant
Ventricular Fibrillation Life Threatening 6/26/2009 71 Male 139 lb 8/16/2013 Consumer Us
Primary
Concomitant
Unevaluable Event Other Serious 8/2003 71 Female 170 lb 12/13/2012 Other Health Professional Us
Primary
Concomitant
Transient Ischaemic Attack Hospitalization Female 135 lb 10/19/2012 Lawyer Us
Primary
Concomitant
Dyspnoea Hospitalization 2010 62 Female 277 lb 9/4/2012 Consumer Us
Primary
Secondary
Concomitant
Respiratory Tract Infection Other Serious 6/12/2012 74 Male 8/28/2013 Pharmacist Us
Primary
Secondary
Concomitant
Death Death 7/9/2012 56 Female 11/14/2012 Other Health Professional Us
Primary
Concomitant
Pruritus Death 9/2010 Male 290 lb 8/30/2012 Consumer Country Not Specified
Primary
Concomitant
Nausea 6/8/2012 9/13/2012 Consumer Us
Primary
Concomitant
Syncope Other Serious 69 Male 227 lb 10/12/2012 Physician Nl
Primary
Concomitant
Peripheral Artery Stenosis Hospitalization 2008 Male 219 lb 9/25/2012 Consumer Country Not Specified
Primary
Concomitant
Vision Blurred Hospitalization Female 10/3/2012 Consumer Us
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/5/2012 69 Female 11/20/2012 Us
Primary
Concomitant
Haemorrhage Subcutaneous 8/14/2012 70 Male 3/14/2013 Physician Kr
Primary
Secondary
Concomitant
Intervertebral Disc Protrusion Other Serious 8/2011 64 Female 181 lb 3/11/2013 Physician Us
Primary
Secondary
Concomitant
Myocardial Ischaemia Hospitalization Male 159 lb 10/31/2012 Physician Za
Primary
Concomitant
Rash Papular 7/6/2012 63 Male 155 lb 11/2/2012 Consumer Us
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious Male 195 lb 11/26/2012 Consumer Country Not Specified
Primary
Concomitant
Pneumonia Hospitalization Male 12/4/2012 Physician Us
Primary
Concomitant
Pyrexia Hospitalization 8/11/2012 65 Male 12/10/2012 Physician Mx
Primary
Concomitant
Food Allergy Female 12/17/2012 Consumer Us
Primary
Secondary
Concomitant
Odynophagia Male 240 lb 12/20/2012 Consumer Us
Primary
Concomitant
Hepatic Cirrhosis Other Serious Female 190 lb 10/31/2012 Consumer Us
Primary
Concomitant
Tachycardia Hospitalization 12/5/2012 76 Female 12/28/2012 Other Health Professional Us
Primary
Concomitant
Pain In Extremity 64 Female 1/8/2013 Consumer Us
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 11/2012 74 Female 215 lb 1/24/2013 Consumer Us
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 12/18/2012 72 Male 2/18/2013 Consumer Co
Primary
Concomitant
Rhinorrhoea Male 215 lb 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Macular Degeneration Other Serious Female 2/14/2013 Physician Us
Primary
Secondary
Concomitant
Skin Burning Sensation 9/23/2011 Male 300 lb 2/25/2013 Consumer Us
Primary
Concomitant
Stent Malfunction Hospitalization Male 3/6/2013 Consumer Us
Primary
Concomitant
Nausea Other Serious 1/2013 52 Male 271 lb 4/1/2013 Consumer Us
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process 2013 Female 3/12/2013 Physician Us
Primary
Concomitant
Arthropathy Hospitalization 4/2001 63 Male 200 lb 4/5/2013 Consumer Us
Primary
Concomitant
Pancreatitis Relapsing Other Serious 12/11/2007 46 Male 242 lb 5/27/2013 Consumer Us
Primary
Concomitant
Vein Disorder Hospitalization 1/26/2006 68 Male 200 lb 3/21/2013 Consumer Us
Primary
Concomitant
Neuropathy Peripheral Other Serious 2013 77 Female 155 lb 5/1/2013 Consumer Us
Primary
Concomitant
Palpitations 3/27/2013 Female 4/16/2013 Us
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 1/2004 67 Male 220 lb 4/16/2013 Physician Us
Primary
Concomitant
Myocardial Infarction Hospitalization 10/4/2007 63 Male 201 lb 4/30/2013 Consumer Us
Primary
Concomitant
Stent Malfunction Hospitalization 10/22/2011 71 Female 5/20/2013 Consumer Us
Primary
Concomitant
Nausea Other Serious 1/2013 52 Male 271 lb 5/25/2013 Consumer Us
Primary
Secondary
Concomitant
Vomiting Other Serious Female 5/30/2013 Consumer Us
Primary
Concomitant
Renal Failure Acute Other Serious 2/19/2013 64 Male 302 lb 7/12/2013 Physician Us
Primary
Concomitant
Sexual Dysfunction Other Serious 2006 64 Male 182 lb 7/22/2013 Other Health Professional Gb
Primary
Concomitant
Sexual Dysfunction Other Serious 2006 64 Male 182 lb 7/23/2013 Other Health Professional Gb
Primary
Concomitant
Sexual Dysfunction Disability 2006 64 Male 182 lb 7/24/2013 Consumer Gb
Primary
Concomitant
Sexual Dysfunction Other Serious 2006 64 Male 182 lb 7/26/2013 Consumer Gb
Primary
Concomitant
Blood Glucose Fluctuation 10/12/2012 66 Female 7/29/2013 Pharmacist Us
Primary
Concomitant
Skin Burning Sensation Female 183 lb 7/30/2013 Consumer Country Not Specified
Primary
Concomitant

Drug Data